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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Unipro UGENE
 
Resource Report
Resource Website
100+ mentions
Unipro UGENE (RRID:SCR_005579) UGENE software toolkit, software resource A multiplatform open-source software to assist molecular biologists without much expertise in bioinformatics to manage, analyze and visualize their data. UGENE integrates widely used bioinformatics tools within a common user interface. The toolkit supports multiple biological data formats and allows the retrieval of data from remote data sources. It provides visualization modules for biological objects such as annotated genome sequences, Next Generation Sequencing (NGS) assembly data, multiple sequence alignments, phylogenetic trees and 3D structures. Most of the integrated algorithms are tuned for maximum performance by the usage of multithreading and special processor instructions. UGENE includes a visual environment for creating reusable workflows that can be launched on local resources or in a High Performance Computing (HPC) environment. UGENE is written in C++ using the Qt framework. The built-in plugin system and structured UGENE API make it possible to extend the toolkit with new functionality. c++, windows, mac os, linux, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22368248
DOI:10.1093/bioinformatics/bts091
GNU General Public License, v2, Acknowledgement requested OMICS_01022, biotools:ugene https://bio.tools/ugene, https://sources.debian.org/src/ugene/ SCR_005579 2026-08-02 09:04:16 170
NGSUtils
 
Resource Report
Resource Website
10+ mentions
NGSUtils (RRID:SCR_001236) NGSUtils software toolkit, software resource A suite of software tools for analyzing and manipulating next-generation sequencing datasets, such as FASTQ, BED and BAM format files. These tools provide a stable and modular platform for data management and analysis. mac os x, linux, next-generation sequencing, illumia, solid, 454, ion torrent, pac bio, sequencing, dna resequcing, rna resequcing, chip-seq, clip-seq, targeted resequencing, agilent exome capture, pcr targeting, dna, rna, mapping pipeline, python, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Indiana University School of Medicine; Indiana; USA
PMID:23314324 Free, Available for download, Freely available biotools:ngsutils, OMICS_02104 https://bio.tools/ngsutils SCR_001236 NGSUtils - Tools for next-generation sequencing analysis 2026-08-02 09:03:04 38
enviPick
 
Resource Report
Resource Website
1+ mentions
enviPick (RRID:SCR_003059) web site, software resource Software for sequential partitioning, clustering and peak detection of centroided LC-MS mass spectrometry data (.mzXML). Interactive result and raw data plot. standalone software, mac os x, unix/linux, windows, r is listed by: OMICtools
has parent organization: CRAN
Free, Available for download, Freely available OMICS_05010 https://rdrr.io/cran/enviPick/ SCR_003059 enviPick: Peak picking for high resolution mass spectrometry data 2026-08-02 09:03:32 2
khmer
 
Resource Report
Resource Website
10+ mentions
khmer (RRID:SCR_001156) software toolkit, software resource Software library and suite of command line tools for working with DNA sequence that takes a k-mer-centric approach to sequence analysis. It is primarily aimed at short-read sequencing data such as that produced by the Illumina platform. dna sequence, short-read, sequencing, dna, illumina, sequence analysis, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NHGRI R01HG007513 PMID:26535114
DOI:10.12688/f1000research.6924.1
Free, Available for download, Freely available SciRes_000166, OMICS_02560, biotools:khmer https://github.com/dib-lab/khmer, https://bio.tools/khmer, https://sources.debian.org/src/khmer/ https://github.com/ged-lab/khmer, http://ged.msu.edu/papers/2012-diginorm/ SCR_001156 khmer project, khmer - k-mer counting & filtering FTW, khmer - k-mer counting and filtering FTW, khmer: k-mer counting filtering and graph traversal FTW 2026-08-02 09:03:00 25
Illuminate
 
Resource Report
Resource Website
1+ mentions
Illuminate (RRID:SCR_000178) Illuminate software toolkit, software resource Python module and utilities to parse the metrics binaries output by Illumina sequencers, and provides usable data in the form of python dictionaries and dataframes. Intended to emulate the output of Illumina SAV, it allows you to print sequencing run metrics to the command line as well as work with the data programmatically. illumina, python is listed by: OMICtools Free, Available for download, Freely available OMICS_02102 SCR_000178 Illuminate - Analytics toolkit for Illumina sequencer metrics 2026-08-02 09:02:48 1
pRESTO
 
Resource Report
Resource Website
50+ mentions
pRESTO (RRID:SCR_001782) pRESTO software toolkit, software resource Software toolkit for processing raw reads from high-throughput sequencing of lymphocyte repertoires. lymphocyte, high throughput sequencing, processing, raw reads, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Yale School of Medicine; Connecticut; USA
EMD/Merck/Serono ;
United States-Israel Binational Science Foundation 2009046;
NCRR RR19895;
NLM T15 LM07056;
NIAAA U19AI089992;
NIAAA U19AI050864
PMID:24618469 Free, Freely available SCR_001782 REpertoire Sequencing TOolkit 2026-08-02 09:03:16 70
Apache Hadoop
 
Resource Report
Resource Website
50+ mentions
Apache Hadoop (RRID:SCR_011879) Hadoop software toolkit, software resource Software library providing a framework that allows for the distributed processing of large data sets across clusters of computers using simple programming models. It is designed to scale up from single servers to thousands of machines, each offering local computation and storage. Rather than rely on hardware to deliver high-availability, the library itself is designed to detect and handle failures at the application layer, so delivering a highly-available service on top of a cluster of computers, each of which may be prone to failures. The project includes these modules: * Hadoop Common: The common utilities that support the other Hadoop modules. * Hadoop Distributed File System (HDFS): A distributed file system that provides high-throughput access to application data. * Hadoop YARN: A framework for job scheduling and cluster resource management. * Hadoop MapReduce: A YARN-based system for parallel processing of large data sets. computing is listed by: OMICtools
has parent organization: Apache Software Foundation
Open unspecified license OMICS_01210 SCR_011879 2026-08-02 09:06:04 57
ALEA
 
Resource Report
Resource Website
50+ mentions
ALEA (RRID:SCR_006417) ALEA software toolkit, software resource A computational software toolbox for allele-specific (AS) epigenomics analysis. It incorporates allelic variation data within existing resources, allowing for the identification of significant associations between epigenetic modifications and specific allelic variants in human and mouse cells. It provides a customizable pipeline of command line tools for AS analysis of next-generation sequencing data (ChIP-seq, RNA-seq, etc.) that takes the raw sequencing data and produces separate allelic tracks ready to be viewed on genome browsers. ALEA takes advantage of the available genomic resources for human (The 1000 Genomes Project Consortium) and mouse (The Mouse Genome Project) to reconstruct diploid in-silico genomes for human or hybrid mice under study. Then, for each accompanying ChIP-seq or RNA-seq dataset, it generates two Wiggle track format (WIG) files from short reads aligned differentially to each haplotype. allele, epigenomics, analysis, chip-seq, rna-seq, allelic variation, next-generation sequencing is listed by: OMICtools
has parent organization: BC Cancer Agency
PMID:24371156 Academic Free License OMICS_02193 SCR_006417 2026-08-02 09:04:54 95
RDKit: Open-Source Cheminformatics Software
 
Resource Report
Resource Website
100+ mentions
RDKit: Open-Source Cheminformatics Software (RRID:SCR_014274) software toolkit, software resource An open-source cheminformatics and machine-learning toolkit that is useable from Java or Python. It includes a collection of standard cheminformatics functionality for molecule I/O, substructure searching, chemical reactions, coordinate generation (2D or 3D), fingerprinting, etc., as well as a high-performance database cartridge for working with molecules using the PostgreSQL database. Documentation is available on the main website. cheminformatics, machine learning, software toolkit, open source, python, c++, FASEB list is listed by: Debian
is listed by: OMICtools
Open source, Acknowledgement requested OMICS_14853 https://github.com/rdkit https://sourceforge.net/projects/rdkit/ https://sources.debian.org/src/python3-rdkit/ SCR_014274 RDKit, RDKit Open-Source Cheminformatics and Machine Learning 2026-08-02 09:06:30 465
Tangram
 
Resource Report
Resource Website
50+ mentions
Tangram (RRID:SCR_006152) software toolkit, software resource A C / C++ command line toolbox for structural variation (SV) detection that reports mobile element insertions (MEI). It takes advantage of both read-pair and split-read algorithms and is extremely fast and memory-efficient. Powered by the Bamtools API, it can call SV events on multiple BAM files (a population) simutaneously to increase the sensitivity on low-coverage dataset. standalone software, c, c++ is listed by: OMICtools PMID:25228379 MIT License OMICS_05785 SCR_006152 2026-08-02 09:04:29 61
Computational Genomics Analysis Tools
 
Resource Report
Resource Website
10+ mentions
Computational Genomics Analysis Tools (RRID:SCR_006390) CGAT software toolkit, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 3, 2023. A collection of tools for the computational genomicist written in the python language to assist in the analysis of genome scale data from a range of standard file formats. The toolkit enables filtering, comparison, conversion, summarization and annotation of genomic intervals, gene sets and sequences. The tools can both be run from the Unix command line and installed into visual workflow builders, such as Galaxy. Please note that the tools are part of a larger code base also including genomics and NGS pipelines. Everyone who uses parts of the CGAT code collection is encouraged to contribute. Contributions can take many forms: bugreports, bugfixes, new scripts and pipelines, documentation, tests, etc. All contributions are welcome. computational genomics, genomics, command-line, next-generation sequencing, python, pipeline, functional enrichment, clustering, metagenomic, contig, variant, analysis, filter, compare, conversion, summarization, annotation is listed by: OMICtools
is related to: Galaxy
has parent organization: University of Oxford; Oxford; United Kingdom
PMID:24395753 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02209 SCR_006390 Computational Genomics Analysis Toolkit, CGAT - Computational Genomics Analysis Tools 2026-08-02 09:04:36 28
Cluster
 
Resource Report
Resource Website
5000+ mentions
Cluster (RRID:SCR_013505) Cluster software toolkit, software resource Software R package. Methods for Cluster analysis. Performs variety of types of cluster analysis and other types of processing on large microarray datasets. Cluster analysis, processing on large microarray datasets is listed by: OMICtools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of California at Berkeley; Berkeley; USA
PMID:14871861 Free, Available for download, Freely available OMICS_01571 http://www.eisenlab.org/eisen/?page_id=42, https://sources.debian.org/src/cluster3/ SCR_013505 Cluster 3.0 2026-08-02 09:06:17 5669
Ghemical
 
Resource Report
Resource Website
10+ mentions
Ghemical (RRID:SCR_014899) software toolkit, software resource Molecular modelling software package with 3D-visualization tools. It supports methods based on both molecular mechanics and quantum mechanics (using MOPAC7, and MPQC for QM). It contains geometry optimization (for MM and QM) and molecular dynamics (for MM) algorithms. molecular modeling, 3d visualization, molecular mechanics, quantum mechanics, geometry organization, molecular dynamics is listed by: Debian
is listed by: OMICtools
Available for download OMICS_21304 https://sources.debian.org/src/ghemical/ https://www.uku.fi/~thassine/projects/ghemical SCR_014899 2026-08-02 09:06:41 18
Fastaq
 
Resource Report
Resource Website
10+ mentions
Fastaq (RRID:SCR_016091) software toolkit, software resource Software application for diverse collection of scripts that perform useful and common FASTA/FASTQ manipulation tasks, such as filtering, merging, splitting, sorting, trimming, search/replace, etc. Input and output files can be gzipped (format is automatically detected) and individual Fastaq commands can be piped together. diverse, script, collect, filter, merge, split, sort, trim, search, replace, file, single-letter code, nucleotide, sequence, peptide, amino acid, text-based, format is listed by: Debian
is listed by: OMICtools
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
Free, Available for download, Freely available OMICS_19987 https://sources.debian.org/src/fastaq/ SCR_016091 2026-08-02 09:07:11 25
Fastqtl
 
Resource Report
Resource Website
100+ mentions
Fastqtl (RRID:SCR_016093) Fastqtl software toolkit, software resource Software for mapping of molecular phenotypes that implements a new permutation scheme to accurately and rapidly correct for multiple-testing at both the genotype and phenotype levels in large-scale datasets. It is used to discover quantitative trait loci, multi-dimensional genomic datasets combining DNA-seq and ChiP-/RNA-seq. molecular, phenotype, multiply, testing, genotype, correct, genomic dataset, trait, loci, cis, quantitative, multi dimensional is listed by: Debian
is listed by: OMICtools
has parent organization: SIB Swiss Institute of Bioinformatics
European Commission SYSCOL FP7;
European Research Council ;
Louis Jeantet Foundation ;
Swiss National Science Foundation ;
SystemsX ;
NIH-NIMH (GTEx) ;
Helse Sør Øst
PMID:26708335 Free, Available for download OMICS_10934 https://sources.debian.org/src/fastqtl/ SCR_016093 Fastqtl: Fast quantitative trait loci 2026-08-02 09:07:14 127
Harvest-tools
 
Resource Report
Resource Website
1+ mentions
Harvest-tools (RRID:SCR_016132) software toolkit, software resource Software tools archiving and postprocessing for reference-compressed genomic multi-alignments. It is used for creating and interfacing with Gingr files, which are archives that the Harvest Suite uses to store reference-compressed multi-alignments, phylogenetic trees, filtered variants and annotations. archiving, postprocessing, reference, compressed, genomic, multialignment, create, interface, Gingr, file, phylogentic, tree, annotation, bioinformatic, format is listed by: Debian
is listed by: OMICtools
Department of Homeland Security Science and Technology Directorate PMID:25410596 Free, Available for download, Freely available OMICS_08468 https://github.com/marbl/harvest-tools, https://sources.debian.org/src/harvest-tools/ SCR_016132 2026-08-02 09:07:15 4
FastTree
 
Resource Report
Resource Website
5000+ mentions
FastTree (RRID:SCR_015501) software resource, source code Source code that infers approximately-maximum-likelihood phylogenetic trees from alignments of nucleotide or protein sequences. It uses the Jukes-Cantor or generalized time-reversible (GTR) models of nucleotide evolution and the JTT, WAG, or LG models of amino acid evolution. phylogenetic tree, phylogenetic tree creation, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is related to: VeryFastTree
PMID:19377059
DOI:10.1371/journal.pone.0009490
biotools:fasttree, OMICS_14703 https://bio.tools/fasttree, https://sources.debian.org/src/fasttree/ SCR_015501 2026-08-03 09:35:59 5774
phytools
 
Resource Report
Resource Website
500+ mentions
phytools (RRID:SCR_015502) software resource, source code Software R package for phylogenetic comparative biology. The package contains various functions for phylogenetic analysis of comparative data from species. r package, phylogenetic comparison, phylogenetic analysis is listed by: Debian
is listed by: OMICtools
is hosted by: GitHub
DOI:10.1111/j.2041-210X.2011.00169.x Available for download, Acknowledgement requested OMICS_12499 https://github.com/liamrevell/phytools, https://sources.debian.org/src/r-cran-phytools/ SCR_015502 2026-08-03 09:36:10 645
Sequence Search and Alignment by Hashing Algorithm
 
Resource Report
Resource Website
1+ mentions
Sequence Search and Alignment by Hashing Algorithm (RRID:SCR_000544) SSAHA2 software resource, source code A program designed for the efficient mapping of sequence reads onto genomic references. The software is capable of reading most sequencing platforms and giving a range of outputs are supported. sequence, genomic, analysis, search, alignment, algorithm, mapping, bio.tools is listed by: OMICtools
is listed by: bio.tools
is related to: SMALT
has parent organization: Wellcome Trust Sanger Institute; Hinxton; United Kingdom
PMID:11591649 THIS RESOURCE IS NO LONGER IN SERVICE biotools:ssaha2, OMICS_00690, nlx_93831 https://bio.tools/ssaha2 SCR_000544 ssaha2, ssaha, Sequence Search and Alignment by Hashing Algorithm 2026-08-03 09:31:04 6
DecGPU
 
Resource Report
Resource Website
1+ mentions
DecGPU (RRID:SCR_000585) software resource Software tool as parallel and distributed error correction algorithm for high-throughput short reads using CUDA and MPI parallel programming models. k-mer based corrector, k-mer spectrum, illumina short read, multistage workflow, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21447171 Free, Available for download, Freely available biotools:decgpu, OMICS_01101, SCR_011850, OMICS_01060 http://musket.sourceforge.net/homepage.htm#latest, https://bio.tools/decgpu SCR_000585 Distributed short read Error Correction on GPUs 2026-08-03 09:31:06 5

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