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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | ||||||||||||||
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Autosomal Recessive Polycystic Kidney Disease Mutation Database Resource Report Resource Website 10+ mentions |
Autosomal Recessive Polycystic Kidney Disease Mutation Database (RRID:SCR_002290) | data or information resource, data repository, database, service resource, storage service resource | Catalog of all changes detected in PKHD1 (Polycystic Kidney and Hepatic Disease 1) in a locus specific database. Investigators are invited to submit their novel data to this database. These data should be meaningful for clinical practice as well as of relevance for the reader interested in molecular aspects of polycystic kidney disease (PKD). There are also some links and information for ARPKD patients and their parents. Autosomal recessive polycystic kidney disease (ARPKD/PKHD1) is an important cause of renal-related and liver-related morbidity and mortality in childhood. This study reports mutation screening in 90 ARPKD patients and identifies mutations in 110 alleles making up a detection rate of 61%. Thirty-four of the detected mutations have not been reported previously. Two underlying mutations in 40 patients and one mutation in 30 cases are disclosed, and no mutation was detected on the remaining chromosomes. Mutations were found to be scattered throughout the gene without evidence of clustering at specific sites. PKHD1 mutation analysis is a powerful tool to establish the molecular cause of ARPKD in a given family. Direct identification of mutations allows an unequivocal diagnosis and accurate genetic counseling even in families displaying diagnostic challenges. | clinical, gene, genetic, mutation, protein, recessive, renal | has parent organization: RWTH Aachen University; Aachen; Germany | Autosomal recessive polycystic kidney disease, Polycystic kidney disease | PMID:16199545 PMID:11919560 |
Permission required, Terms of use | nif-0000-21038 | http://www.humgen.rwth-aachen.de/index.asp?subform=database.html&nav=database_nav.html | SCR_002290 | SciCrunch Registry | Mutation Database Autosomal Recessive Polycystic Kidney Disease (ARPKD/PKHD1) | 2026-11-07 11:54:36 | 14 | |||||
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GEISHA - Gallus Expression in Situ Hybridization Analysis: A Chicken Embryo Gene Expression Database Resource Report Resource Website 1+ mentions |
GEISHA - Gallus Expression in Situ Hybridization Analysis: A Chicken Embryo Gene Expression Database (RRID:SCR_007440) | GEISHA | atlas, data or information resource, data repository, database, experimental protocol, narrative resource, service resource, storage service resource | Online repository for chicken in situ hybridization information. This site presents whole mount in situ hybridization images and corresponding probe and genomic information for genes expressed in chicken embryos in Hamburger Hamilton stages 1-25 (0.5-5 days). The GEISHA project began in 1998 to investigate using high throughput whole mount in situ hybridization to identify novel, differentially expressed genes in chicken embryos. An initial expression screen of approximately 900 genes demonstrated feasibility of the approach, and also highlighted the need for a centralized repository of in situ hybridization expression data. Objectives: The goals of the GEISHA project are to obtain whole mount in situ hybridization expression information for all differentially expressed genes in the chicken embryo between HH stages 1-25, to integrate expression data with the chicken genome browsers, and to offer this information through a user-friendly graphical user interface. In situ hybridization images are obtained from three sources: 1. In house high throughput in situ hybridization screening: cDNAs obtained from several embryonic cDNA libraries or from EST repositories are screened for expression using high throughput in situ hybridization approaches. 2. Literature curation: Agreements with journals permit posting of published in situ hybridization images and related information on the GEISHA site. 3. Unpublished in situ hybridization information from other laboratories: laboratories generally publish only a small fraction of their in situ hybridization data. High quality images for which probe identity can be verified are welcome additions to GEISHA. | expression data, expression pattern, gene, gene expression, genome, chicken, chicken embryo, genomic, in situ hybridization, mapping, microarray, microrna, model organism, oligo, probe, stage, image, molecular neuroanatomy resource, embryo, embryonic chicken | has parent organization: University of Arizona; Arizona; USA | NIH ; NICHD R01HD044767 |
nif-0000-01251, r3d100012509 | https://doi.org/10.17616/R3RB6B | SCR_007440 | SciCrunch Registry | Gallus Expression in Situ Hybridization Analysis, GEISHA - Gallus Expression in Situ Hybridization Analysis | 2026-11-07 11:56:14 | 2 | ||||||
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Protein Mutant Database Resource Report Resource Website 1+ mentions |
Protein Mutant Database (RRID:SCR_007878) | PMD | data or information resource, data repository, database, service resource, storage service resource | It provides information on natural and artificial mutants, including random and site-directed ones, for all proteins except members of the globin and immunoglobulin families. The PMD is based on literature, and each entry in the database corresponds to one article which may describe one, several or a number of protein mutants. Each database entry is identified by a serial number and is defined as either natural or artificial, depending on the type of the mutation. For each entry the following are recorded : JOURNAL, TITLE, CROSS-REFERENCE, PROTEIN, N-TERMINAL, CHANGE, FUNCTION, STRUCTURE, STABILITY, etc. CROSS-REFERENCE indicates the code names of the protein given in other databases such as Protein Identification Resources (2). N-TERMINAL shows the N-terminal sequence of five amino acids which may help to show the unambiguous numbering of th e sequence. CHANGE indicates the position and kind of mutations, such as amino acid substitution, insertion and deletion, denoted with a specific notation. Any functional or structural features (FUNCTION, STRUCTURE, STABILITY,etc) observed in the mutant are described immediately after ''CHANGE''. Relative differences in activity and/or stability, in comparison with the wild-type protein, are indicated with symbols (- -),(-),(=),(+) or (+ +). Complete loss of activity is denoted as (0). Data Submission A data submission system was newly prepared in the PMD. We welcome the authors of articles published in academic journals to submit their own mutant data to the PMD. After checking the contents, we will register the data with a unique accession number. | amino acid, artificial, deletion, insertion, mutant, natural, protein, sequence, substitution |
is related to: PredictSNP has parent organization: National Institute of Genetics; Shizuoka; Japan |
SCR_007878 | SciCrunch Registry | Protein Mutant Database | 2026-11-07 11:56:26 | 4 | |||||||||
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BovMap Database Resource Report Resource Website 1+ mentions |
BovMap Database (RRID:SCR_008145) | BovMap | data or information resource, data repository, database, service resource, storage service resource | THIS RESOURCE IS NO LONGER IN SERVICE, documented August 22, 2016. Database containing information on the cattle genome comprising loci list, phenes list, homology query, cattle maps, gene list, and chromosome homology. The objective of BovMap is to develop a set of anchored loci for the cattle genome map. In total, 58 clones were hybridized with chromosomes and identified loci on 22 of the 31 different bovine chromosomes. Three clones contained satellite DNA. Two or more markers were placed on 12 chromosomes. Sequencing of the microsatellites and flanking regions was performed directly from 43 cosmids, as previously reported. Primers were developed for 39 markers and used to describe the polymorphism associated with the corresponding loci. Users are also allowed to summit their own data for Bovmap. An integrated cytogenetic and meiotic map of the bovine genome has also been developed around the Bovmap database. One objective that Bovmap uses as the mapping strategy for the bovine genome uses large insert clones as a tool for physical mapping and as a source of highly polymorphic microsatellites for genetic typing. | genetic, bovine, cattle, chromosome, clone, cosmid, cow, cytogenetic, dna, genome, homology, locus, meiotic, phene, polymorphism, sequence, map, gene | has parent organization: INRA - French National Institute for Agricultural Research; Paris; France | European Union | THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-20968 | SCR_008145 | SciCrunch Registry | 2026-11-07 11:56:26 | 2 | |||||||
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eagle-i research resource ontology Resource Report Resource Website 1+ mentions |
eagle-i research resource ontology (RRID:SCR_008784) | ERO | controlled vocabulary, data or information resource, data repository, database, ontology, service resource, software application, software resource, source code, storage service resource | Ontology that models research resources such as instruments, protocols, reagents, animal models and biospecimens. It has been developed in the context of the eagle-i project (http://eagle-i.net/) and consists of over 3451 classes of which over 1200 were created within the ERO namespace, while the rest come from existent ontologies such as the Ontology for Biomedical Investigation (OBI), the uber-anatomy ontology (Uberon), VIVO, the Ontology for Clinical Research (OCRe), the Sequence Ontology (SO), the Software Ontology (SWO) and we include terms from the NCBI Taxonomy as well. The main ontology can be browsed in OntoBee. All purls resolve to OntoBee. | research, resource, biomedical, owl |
is listed by: BioPortal is related to: Ontobee is related to: CTSA ShareCenter has parent organization: Eagle I has parent organization: Google Code |
ARRA ; NCRR U24RR029825 |
New BSD License | nlx_144312 | SCR_008784 | SciCrunch Registry | 2026-11-07 11:56:38 | 1 | |||||||
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BrainPeps Resource Report Resource Website 1+ mentions |
BrainPeps (RRID:SCR_008851) | Brainpeps | data or information resource, data repository, database, service resource, storage service resource | Database of blood-brain barrier properties of peptides including structure, method, responses, physicochemical properties and related literature. The database is linked to a manuscript entitled Brainpeps: the blood-brain barrier peptide database, in which the BBB methods and responses are clarified and correlated to each other. Data may be submitted for addition to the database. | peptide, intravenous injection, efflux study, immortal cell line, brain slice, ultracentrifugation, bui method, capillary depletion, iam-hplc, indicator diffusion, bmec, shake flask, non-cerebral cell line, in vitro equilibrium dialysis, microdialysis, imaging techniques, quantitative autoradiography, antinociception, hplc, in situ brain perfusion, (co)-culture, mbua, ultrafiltration, cisternal puncture, bei method, gibbs adsorption isotherm, pampa, blood-brain barrier, brain, permeability, distribution, data set |
is listed by: 3DVC has parent organization: Ghent University; Ghent; Belgium |
Institute for the Promotion of Innovation through Science and Technology in Flanders IWT-Vlaanderen 73402 | PMID:22205159 | Acknowledgement requested, The community can contribute to this resource | nlx_149082 | SCR_008851 | SciCrunch Registry | Brain Peps | 2026-11-07 11:56:37 | 2 | |||||
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TOPSAN Resource Report Resource Website 10+ mentions |
TOPSAN (RRID:SCR_005758) | TOPSAN | data or information resource, data repository, database, image collection, service resource, storage service resource | Collect, share, and distribute information about protein three-dimensional structures. It serves as a portal for the scientific community to learn about protein structures solved by SG centers, and also to contribute their expertise in annotating protein function. The premise of the TOPSAN project is that, no matter how much any individual knows about a particular protein, there are other members of the scientific community who know more about certain aspects of the same protein, and that the collective analyses from experts will be far more informative than any local group, let alone individual, could contribute. They believe that, if the members of the biological community are given the opportunity, authorship incentives, and an easy way to contribute their knowledge to the structure annotation, they would do so. Therefore, borrowing elements from successful, distributed, collaborative projects, such as Wikipedia (the free encyclopedia anyone can edit) and from other open source software development projects, TOPSAN will be a broad, collaborative effort to annotate protein structures, initially, those determined at the JCSG. They believe that the annotation of proteins solved by structural genomics consortia offers a unique opportunity to challenge the extant paradigm of how biological data is collected and distributed, and to connect structural genomics and structural biology to the entire biological research community. TOPSAN is designed to be scalable, modular and extensible. Furthermore, it is intended to be immediately useful in a simplistic way and will accommodate incremental improvements to functionality as usage becomes more sophisticated. Their annotation pages will offer the end user a combination of automatically generated as well as expert-curated annotations of protein structures. They will use available technology to increase the speed and granularity of the exchange of scientific ideas, and use incentive mechanisms that will encourage collaborative participation. | protein, structure, 3d, protein structure, protein function, annotate, crowd sourcing, image, annotation, genomics, collaboration |
has parent organization: Sanford Burnham Prebys Medical Discovery Institute has parent organization: University of California at San Diego; California; USA |
NIGMS U54 GM074898; NIGMS P20 GM076221 |
PMID:20961957 PMID:20716366 PMID:20944203 PMID:20961957 |
Creative Commons Attribution v3 License, The community can contribute to this resource | nlx_149221 | SCR_005758 | SciCrunch Registry | he Open Protein Structure Annotation Network, TOPSAN Project, TOPSAN - The Open Protein Structure Annotation Network | 2026-11-07 11:55:40 | 10 | |||||
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Crystallography Open Database (COD) Resource Report Resource Website 10+ mentions |
Crystallography Open Database (COD) (RRID:SCR_005874) | COD | data or information resource, data repository, database, service resource, storage service resource | Database of crystal structures of organic, inorganic, metal-organic compounds and minerals, excluding biopolymers. It currently contains ~291204 entries (July 2014) in crystallographic information file format, with nearly full coverage of the International Union of Crystallography publications, and is growing in size and quality. Deposit your data: An interface allows you to upload, validate and edit CIF files before submitting them for deposition. | inorganic, metal-organic, organic, molecule, structure, small molecule, compound, mineral, crystal structure, crystallography, polymorphism, crystal, organic compound |
is recommended by: NIDDK Information Network (dkNET) is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is listed by: re3data.org has parent organization: Vilnius University; Vilnius; Lithuania |
Research Council of Lithuania contract MIP-124/2010 | PMID:22070882 PMID:22477773 |
Public domain, The community can contribute to this resource, Acknowledgement requested | r3d100010213, nlx_149430 | https://doi.org/10.17616/R37S31 | SCR_005874 | SciCrunch Registry | COD - Crystallography Open Database, Crystallography Open Database, Crystallography Open Database (COD), COD | 2026-11-07 11:56:08 | 23 | ||||
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UMD-BRCA1/ BRCA2 databases Resource Report Resource Website 10+ mentions |
UMD-BRCA1/ BRCA2 databases (RRID:SCR_006128) | UMD-BRCA1/ BRCA2 databases | data or information resource, data repository, database, service resource, storage service resource | The UMD-BRCA1/BRCA2 databases have been set up in a joined national effort through the network of 16 diagnostic laboratories to provide up-to-date information about mutations of the BRCA1 and BRCA2 genes identified in patients with breast and/or ovarian cancer. These databases currently contain published and unpublished information about the BRCA1/BRCA2 mutations reported in French diagnostic laboratories. This database includes 28 references and 5530 mutations (1440 different mutations and 786 protein variants) The databases of BRCA1 and BRCA2 mutations were built using the Universal Mutation Database tool. For each mutation, information is provided at several levels: * at the gene level: exon and codon number, wild type and mutant codon, mutation event, mutation name and, * at the protein level: wild type and mutant amino acid, binding domain, affected domain. If you want to submit a mutation, please contact R. Lidereau., S. Caputo. or E. Rouleau. | cancer, gene, mutation, exon, codon, wild type, mutant, mutation, protein, amino acid, binding domain, affected domain, brca1, brca2, variant, polymorphism, unclassified variant, unknown variant, female, woman, bio.tools |
is listed by: Debian is listed by: bio.tools has parent organization: National Institute of Health and Medical Research; Rennes; France |
Breast cancer, Ovarian cancer | French National Cancer Institute ; European Union FP7/2007-2013; Association dAide a la Recherche Cancerologique de Saint Cloud |
PMID:22144684 | The UMD- BRCA1 Locus Specific Databases constitute the intellectual property of the curators of the database. Any unauthorized copying, Storage or distribution of this material without written permission from the curators would lead to copyright infringement with possible ensuing litigation. | biotools:brca_share, nlx_151608 | https://bio.tools/brca_share | SCR_006128 | SciCrunch Registry | UMD-BRCA1 mutations database, UMD-BRCA1 / BRCA2 databases, UMD-BRCA1/BRCA2 databases | 2026-11-07 11:56:11 | 26 | |||
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Antibody Registry Resource Report Resource Website 100+ mentions |
Antibody Registry (RRID:SCR_006397) | data or information resource, data repository, database, service resource, storage service resource | Public registry of antibodies with unique identifiers for commercial and non-commercial antibody reagents to give researchers a way to universally identify antibodies used in publications. The registry contains antibody product information organized according to genes, species, reagent types (antibodies, recombinant proteins, ELISA, siRNA, cDNA clones). Data is provided in many formats so that authors of biological papers, text mining tools and funding agencies can quickly and accurately identify the antibody reagents they and their colleagues used. The Antibody Registry allows any user to submit a new antibody or set of antibodies to the registry via a web form, or via a spreadsheet upload. | RIN, Resource Information Network, antibody, reagent, unique identifiers, RRID Community Authority, |
is used by: Resource Identification Portal is used by: NIF Data Federation is used by: NIDDK Information Network (dkNET) is listed by: OMICtools is listed by: FORCE11 is listed by: re3data.org is listed by: Resource Information Network is related to: Novus Biologicals is related to: DOMEO is related to: Journal of Comparative Neurology Antibody database is related to: Integrated Manually Extracted Annotation has parent organization: Neuroscience Information Framework |
NIDA ; NIH Blueprint for Neuroscience Research ; U.S. Department of Health and Human Services HHSN27120080035C |
Creative Commons Attribution License, The community can contribute to this resource | biodbcore-000182, nif-0000-07730, OMICS_01768, r3d100010408 | https://doi.org/10.17616/R3XG7N | SCR_006397 | SciCrunch Registry | AntibodyRegistry, AB Registry, The Antibody Registry, ABRegistry | 2026-11-07 11:55:52 | 111 | ||||||
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FlyBase Resource Report Resource Website 1000+ mentions |
FlyBase (RRID:SCR_006549) | FB | data or information resource, data repository, database, organism-related portal, portal, service resource, storage service resource, topical portal | Database of Drosophila genetic and genomic information with information about stock collections and fly genetic tools. Gene Ontology (GO) terms are used to describe three attributes of wild-type gene products: their molecular function, the biological processes in which they play a role, and their subcellular location. Additionally, FlyBase accepts data submissions. FlyBase can be searched for genes, alleles, aberrations and other genetic objects, phenotypes, sequences, stocks, images and movies, controlled terms, and Drosophila researchers using the tools available from the "Tools" drop-down menu in the Navigation bar. | RIN, Resource Information Network, mutant, gene, genome, blast, genotype, phenotype, allele, sequence, stock, image, movie, controlled term, video resource, image collection, life-cycle, genome, expression, rna-seq, genetics, drosophilidae, bio.tools, FASEB list, RRID Community Authority |
is used by: NIF Data Federation is used by: Resource Identification Portal is used by: PhenoGO is used by: Integrated Animals is used by: Drososhare is recommended by: NIDDK Information Network (dkNET) is recommended by: National Library of Medicine is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is listed by: re3data.org is listed by: OMICtools is listed by: bio.tools is listed by: Debian is listed by: Resource Information Network is related to: FlyMine is related to: Virtual Fly Brain is related to: AmiGO is related to: Drosophila melanogaster Exon Database is related to: HomoloGene is related to: UniParc at the EBI is related to: UniParc is related to: Gene Ontology is related to: NIH Data Sharing Repositories is related to: GBrowse is related to: Integrated Manually Extracted Annotation is related to: PhenoGO has parent organization: Harvard University; Cambridge; United States has parent organization: University of Cambridge; Cambridge; United Kingdom has parent organization: Indiana University; Indiana; USA has parent organization: University of New Mexico; New Mexico; USA is parent organization of: Drosophila anatomy and development ontologies is parent organization of: Fly Taxonomy is parent organization of: FlyBase Controlled Vocabulary is parent organization of: Drosophila Development Ontology is organization facet of: Alliance of Genome Resources |
Indiana Genomics Initiative ; MRC ; NIH Blueprint for Neuroscience Research ; NIHGRI P41 HG000739; NSF |
PMID:24234449 PMID:22127867 PMID:18948289 PMID:18641940 PMID:18160408 PMID:17099233 PMID:16381917 PMID:15608223 PMID:12519974 PMID:11752267 PMID:11465064 PMID:9847148 PMID:9399806 PMID:9045212 PMID:8594600 PMID:8578603 PMID:7937045 PMID:7925011 |
nif-0000-00558, r3d100010591, OMICS_01649, biotools:flybase | https://bio.tools/flybase, https://doi.org/10.17616/R3903Q | http://flybase.net | SCR_006549 | SciCrunch Registry | flybase A Drosophila Genomic and Genetic Database, FlyBase: A Database of Drosophila Genes and Genomes, FLYBASE, FlyBase: A Database of Drosophila Genes & Genomes, FB | 2026-11-07 11:55:56 | 4234 | ||||
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Psychoactive Drug Screening Program Ki Database Resource Report Resource Website 10+ mentions |
Psychoactive Drug Screening Program Ki Database (RRID:SCR_003281) | Ki DB | data or information resource, data repository, database, service resource, storage service resource | THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 5, 2023. Database of information on the abilities of drugs to interact with an expanding number of molecular targets. It serves as a data warehouse for published and internally-derived Ki, or affinity, values for a large number of drugs and drug candidates at an expanding number of G-protein coupled receptors, ion channels, transporters and enzymes. The query interface is designed to let you search by any field, or combination of them to refine your search criteria. The flexible user interface also provides for customized data mining. The database is regularly updated. If you know of Ki data you would like to add, you can select Direct Ki Entry at the grey panel. If you would like, however, your own data (published or not) added, Send them a Reference at the grey panel, or send an email to Dr. Bryan Roth or Estela Lopez. Most common targets: 5-HT2A, DOPAMINE D1, DOPAMINE D2, 5-HT2C, 5-HT1A, Cholinergic, muscarinic M1, 5-HT Transporter, HISTAMINE H1, 5-HT2B, OPIOID Mu, 5-HT6, adrenergic Beta2, 5-HT7, OPIATE Delta, adrenergic Alpha1A, OPIOID Kappa, 5-HT3, m-AChR, adrenergic Beta1, adrenergic Alpha2A, 5-HT1, Acetylcholinesterase, AChE, Thromboxane A2, n-AChR, Opiate non-selective, CANNABINOID CB1, HERG, Dopamine, cocaine site, adrenergic Alpha2C, M3, Norepinephrine Uptake, Monoamine Oxidase A, Monoamine Oxidase B, 5-HT4, adrenergic Alpha1, 5-HT1E, B1 BRADYKININ, 5-HT2, 5-HT2C-INI, DOPAMINE D4, ANGIOTENSIN AT1, Neurokinin NK1, HISTAMINE H3, Sigma-1, VIP, Dopamine2-like, metabotropic glutamate 5, 5-HT2c VGI, Carbonic Anhydrase Isozymes, CA I, DOPAMINE D2 Long, adrenergic Alpha2, adrenergic Alpha2B, adrenergic Alpha2D, GABA A alpha1, CANNABINOID CB2, adrenergic Alpha1B, 5-HT5a, Melatonin, HISTAMINE H4, NMDA, 5-HT4a, Glucocorticoid, Interleukin 1-beta, Sodium Channel, Benzodiazepine central, Cholinergic, muscarinic M5, Neuropeptide Y1, GABA A alpha5, Galanin R2, Neurokinin NK3, 5-HT1B, M2, DOPAMINE D3, Angiotensin, Dopamine1-like, Neurokinin NK2, adrenergic Beta, Dopamine D1 high, Dopamine D1A, MAP kinase, ADENOSINE A2a, 5-HT7b, Nitrogen oxide synthase - neuronal, Sigma-2, CDK2, Neurotensin 2, DOPAMINE D2 Short, Multidrug Resistance Transporter MDR 1, GABA A Benzodiazepine, VEGF-R2, OPIATE Mu 2, Angiotensin II AT1, HISTAMINE H2, Angiotensin-converting enzyme, ACE, Sigma, beta-amyloid, ADENOSINE, ADENOSINE A2B, Adrenaline, Neurotensin 1 | gpcr, ki, 5-ht transporter, 5-ht2a, dopamine d2, dopamine d1, 5-ht1a, m1, dopamine transporter, opiate mu, histamine h1, adrenergic alpha1, 5-ht7, m2, 5-ht2c, cannabinoid cb1, adrenergic alpha2a, net, 5-ht3, 5-ht2b, adrenergic alpha1a, adrenergic beta1 |
is used by: NIF Data Federation has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA |
NIMH ; Heffter Research Institute |
THIS RESOURCE IS NO LONGER IN SERVICE | nif-0000-01866 | SCR_003281 | SciCrunch Registry | Ki Database, PDSP Ki Database | 2026-11-07 11:54:59 | 19 | ||||||
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RNA Modification Database Resource Report Resource Website 10+ mentions |
RNA Modification Database (RRID:SCR_003535) | RNAmods | data or information resource, data repository, database, service resource, storage service resource | The RNA modification database provides a comprehensive listing of posttranscriptionally modified nucleosides from RNA. Information provided for each nucleoside includes: the type of RNA in which it occurs and phylogenetic distribution; common chemical name and symbol; Chemical Abstracts registry number and index name; chemical structure; initial literature citations for structural characterization or occurrence, and for chemical synthesis. Both the structural diversity and extent of posttranscriptional modification in RNA is remarkable, with 107 different nucleosides presently known in all types of RNA. The discovery of new modified nucleosides as well as increasing knowledge of the array of functional roles of modification, based largely on extensive studies of tRNA, mandates a need for a comprehensive database of RNA nucleosides. The RNA Modification Database is maintained as an extension of the initial version published in mid-1994. The database consists of all RNA-derived ribonucleosides of known structure, including those from established sequence positions, as well as those detected or characterized from hydrolysates of RNA. The information provided permits access to the modified nucleoside literature through provision of both computer-searchable Chemical Abstracts registry numbers and key literature citations. This database also provides an historical record of the initial reports of occurrence, characterization and chemical synthesis of modified nucleosides from RNA. It is our judgement that the total number of RNA nucleosides listed, and the chemical structures reported, are very accurate. However, the distributions listed are in some cases a matter of concern, due primarily to the possibility of inhomogeneity of the RNA isolate and the use of methods of nucleoside identification that are not sufficiently rigorous. Reinvestigation of some of the unusual or single-report source distributions is warranted, and will likely lead to future refinements in the listings. The authors invite comments concerning new entries, errors or omissions and on the format presently used for electronic access to the database. |
has parent organization: University at Albany; New York; USA has parent organization: University of Utah; Utah; USA |
NIGMS GM29812 | PMID:9399834 PMID:9016519 |
nif-0000-03414 | http://medlib.med.utah.edu/RNAmods/ | SCR_003535 | SciCrunch Registry | 2026-11-07 11:55:08 | 24 | |||||||
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HathiTrust Resource Report Resource Website 10+ mentions |
HathiTrust (RRID:SCR_004128) | HathiTrust | book, catalog, community building portal, data or information resource, data repository, database, narrative resource, portal, service resource, storage service resource | A partnership of academic and research institutions, offering a collection of millions of titles digitized from libraries around the world. Their goals are: * To build a reliable and increasingly comprehensive digital archive of library materials converted from print that is co-owned and managed by a number of academic institutions. * To dramatically improve access to these materials in ways that, first and foremost, meet the needs of the co-owning institutions. * To help preserve these important human records by creating reliable and accessible electronic representations. * To enable the digital archive to be accessible to persons who have print disabilities. * To stimulate redoubled efforts to coordinate shared storage strategies among libraries, thus reducing long-term capital and operating costs of libraries associated with the storage and care of print collections. * To create and sustain this public good in a way that mitigates the problem of free-riders. * To create a technical framework that is simultaneously responsive to members through the centralized creation of functionality and sufficiently open to the creation of tools and services not created by the central organization. | library, digital, digital archive | has parent organization: University of Michigan; Ann Arbor; USA | Acknowledgement requested, Free, Exceptions apply - refer to Access and Use statement, Fee to be a partner | nlx_158610 | SCR_004128 | SciCrunch Registry | HathiTrust Digital Library | 2026-11-07 11:55:09 | 28 | |||||||
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scn1a Resource Report Resource Website 10+ mentions |
scn1a (RRID:SCR_006987) | SCN1A Infobase | data or information resource, data repository, database, service resource, storage service resource |
THIS RESOURCE IS NO LONGER IN SERVICE, documented on August 29,2019. Locus-specific database listing variants of the SCN1A gene. To provide a continued platform that is in keeping with the latest data, this web site has been set up where all information can be accessed and downloaded. A Mutation submission form encourages data submissions. Over the past ten years, mutations in voltage-gated sodium channels (Navs) have become closely associated with inheritable forms of epilepsy. One isoform in particular, Nav1.1 (gene symbol SCN1A), appears to be a superculprit, with virtually hundreds of mutations. The associated phenotypes range from benign febrile seizures to extremely serious conditions like Dravet syndrome (a.k.a. severe myoclonic epilepsy in infancy or SMEI). Despite the wealth of information, mutational analyses are cumbersome, owing to inconsistencies among the Nav1.1 sequences to which different research groups refer. Splicing variability is the core problem: Nav1.1 exists in the brain in 3 different isoforms: full-length (2009 AA) as well as two shorter versions that lack 11 or 28 amino acids compared to the former. This online database ?????? SCN1A infobase ?????? establishes a standardized nomenclature for Nav1.1 variants so as to provide a platform from which future mutation analyses can be started without up-front data normalization. |
scn1a, nav1.1, variation, epilepsy, dravet, smei, gefs, locus-specific, mutation, voltage-gated sodium channel, seizure, sodium channel, scn1a mutation | has parent organization: UC Davis School of Medicine; California; USA | private endeavor | PMID:18804930 | THIS RESOURCE IS NO LONGER IN SERVICE | nlx_143761 | http://web.scn1a.info, http://www.scn1a.info | SCR_006987 | SciCrunch Registry | The SCN1A Infobase | 2026-11-07 11:56:19 | 25 | ||||
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Androgen Receptor Gene Mutations Database Resource Report Resource Website 50+ mentions |
Androgen Receptor Gene Mutations Database (RRID:SCR_006887) | AR Mutation DB, AndrogenDB | data or information resource, data repository, database, service resource, storage service resource |
Comprehensive listing of androgen receptor gene mutations published in journals and meetings proceedings. The majority of mutations are point mutations identified in patients with androgen insensitivity syndrome. Information is included regarding the phenotype, the nature and location of the mutations, as well as the effects of the mutations on the androgen binding activity of the receptor. In light of the difficulty in getting new AR mutations published the curator will now accept new mutations that have not been published, provided that it is from a reputable research or clinical laboratory. The database incorporates information on the exon 1 CAG repeat expansion disease, spinobulbar muscular atrophy (SBMA), as well as CAG repeat length variations associated with risk for female breast, uterine endometrial, colorectal, and prostate cancer, as well as for male infertility. The possible implications of somatic mutations, as opposed to germline mutations, in the development of future locus-specific mutation databases (LSDBs) is discussed. The database now provides information on the external genitalia and on sex - of - rearing. Additionally, the new version of the database has an entry to show if pathogenicity has been proven. A pdf and fully searchable version of the Database is available for download. |
genitalia, gene, androgen, androgen insensitivity syndrome, androgen receptor, biochemical property, disease, kinetic property, mutation, phenotype, sex-of-rearing, genotype, FASEB list | has parent organization: McGill University; Montreal; Canada | Androgen insensitivity syndrome | Canadian Institutes of Health Research | PMID:22334387 PMID:15146455 PMID:7937057 |
The community can contribute to this resource | nif-0000-02547, r3d100012038 | https://doi.org/10.17616/R3PH1J | http://www.mcgill.ca/androgendb/ | SCR_006887 | SciCrunch Registry | Androgen Receptor Gene Mutations Database World Wide Web Server | 2026-11-07 11:56:04 | 57 | ||
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PrimerBank Resource Report Resource Website 1000+ mentions |
PrimerBank (RRID:SCR_006898) | PrimerBank | data or information resource, data repository, database, service resource, storage service resource | Database of human and mouse primer pairs for gene expression analysis by polymerase chain reaction (PCR) and quantitative PCR (qPCR). A total of 306,800 primers covering most known human and mouse genes can be accessed from the PrimerBank database, together with information on these primers such as T(m), location on the transcript and amplicon size. For each gene, at least one primer pair has been designed and in many cases alternative primer pairs exist. Primers have been designed to work under the same PCR conditions, thus facilitating high-throughput QPCR. All primers in PrimerBank were carefully designed to ensure gene specificity. All experimental validation data for mouse primers are available from PrimerBank. You can submit your primers. They will be added to the database once they are properly QCd. | electrophoresis, gene expression, quantitative pcr, gel, gene, agarose, algorithm, amplification, human, molecular probe, primer database, mouse, pcr, primer, primer pair, protein, quantification, reaction, secondary structure, polymerase chain reaction, real-time pcr, pcr primer, detection, blast, bio.tools, FASEB list |
is listed by: OMICtools is listed by: bio.tools is listed by: Debian has parent organization: Harvard Medical School; Massachusetts; USA |
NHLBI U01 HL66678 | PMID:22086960 PMID:19906719 PMID:19108745 PMID:14654707 |
Public, Acknowledgement requested, The community can contribute to this resource | nif-0000-21333, OMICS_02323, biotools:primerbank | https://bio.tools/primerbank | SCR_006898 | SciCrunch Registry | PrimerBank: PCR Primers for Gene Expression Detection and Quantification | 2026-11-07 11:56:16 | 1709 | ||||
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dbSNP Resource Report Resource Website 5000+ mentions |
dbSNP (RRID:SCR_002338) | dbSNP | data or information resource, data repository, database, service resource, storage service resource | General database of genetic variations maintained by the NCBI. Database as central repository for both single base nucleotide substitutions and short deletion and insertion polymorphisms. Distinguishes report of how to assay SNP from use of that SNP with individuals and populations. This separation simplifies some issues of data representation. However, these initial reports describing how to assay SNP will often be accompanied by SNP experiments measuring allele occurrence in individuals and populations. Community can contribute to this resource. | insertion, polymorphism, short, deletion, single, nucleotide, genetic, variation, genomics, genotype, disease, allele, microsatellite, marker, multinucleotide, heterozygous, sequence, gold standard, bio.tools |
is used by: ExAc is used by: GEMINI is recommended by: National Library of Medicine is recommended by: NIDDK Information Network (dkNET) is recommended by: NIDDK - National Institute of Diabetes and Digestive and Kidney Diseases is listed by: OMICtools is listed by: re3data.org is listed by: bio.tools is listed by: Debian is related to: Ensembl Variation is related to: GWAS Central is related to: TopoSNP is related to: GWAS Central is related to: dbSNP151 has parent organization: NCBI has parent organization: National Human Genome Research Institute works with: Open Regulatory Annotation Database |
NLM | PMID:21154707 | Free, Freely available | nif-0000-02734, biotools:dbsnp, OMICS_00264, r3d100010652 | http://www.ncbi.nlm.nih.gov/projects/SNP/, https://bio.tools/dbsnp, https://doi.org/10.17616/R3XG81 | SCR_002338 | SciCrunch Registry | dbSNP: Database for Short Genetic Variations, Entrez SNP - Single Nucleotide Polymorphism, SNV Database, NCBI SNV Database, NCBI Short Genetic Variations Database, NCBI Short Genetic Variations, NCBI Single Nucleotide Polymorphism, Entrez SNP, dbSNP, NCBI Short Genetic Variations (SNV) database | 2026-11-07 11:54:37 | 9088 | ||||
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Current Controlled Trials Resource Report Resource Website 1000+ mentions |
Current Controlled Trials (RRID:SCR_002325) | CCT | data or information resource, data repository, database, service resource, storage service resource | Free-to-view clinical trials register of clinical trials worldwide, it allows users to search, register and share information about randomized controlled trials. Publication services are also available via the range of open access peer-reviewed journals published by BioMed Central. Current Controlled Trials is run by an editorial and technical in-house team. It receives advice from an international Advisory Group, including academics, doctors and health care specialists of international renown. The Advisory Group provides valuable guidance on the current activities and possible new directions of Current Controlled Trials' two databases, the metaRegister of Controlled Trials (mRCT) and the International Standard Randomised Controlled Trial Number (ISRCTN) scheme. | controlled trial, health, public health, science, trial, randomized controlled trial, clinical trial, FASEB list |
uses: ISRCTN Registry is related to: ISRCTN Registry is parent organization of: ISRCTN Registry |
Science Navigation Group ; European Union ; administrative fee |
Free and open access | nif-0000-21104 | http://www.webcitation.org/getfile?fileid=6fc2d850dde348335d1ab0b66828190d475a6967 | SCR_002325 | SciCrunch Registry | Current Controlled Trials Ltd | 2026-11-07 11:54:55 | 1471 | |||||
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ENZYME Resource Report Resource Website 100+ mentions |
ENZYME (RRID:SCR_002487) | ENZYME | data or information resource, data repository, database, service resource, storage service resource | A repository of information relative to the nomenclature of enzymes. It is primarily based on the recommendations of the Nomenclature Committee of the International Union of Biochemistry and Molecular Biology (IUBMB) and it describes each type of characterized enzyme for which an EC (Enzyme Commission) number has been provided. These include * EC number * Recommended name * Alternative names (if any) * Catalytic activity * Cofactors (if any) * Pointers to the Swiss-Prot protein sequence entry(ies) that correspond to the enzyme (if any) * Pointers to human disease(s) associated with a deficiency of the enzyme (if any) We believe that the ENZYME database can be useful to anybody working with enzymes and that it can be of help in the development of computer programs involved with the manipulation of metabolic pathways. Available services include downloading ENZYME by FTP as well as report forms for a new ENZYME entry or for an error/update in an existing entry. | enzyme commission, enzyme name, nomenclature, enzyme categories, enzyme classification, enzyme nomenclature, enzyme reaction categories, gold standard |
is used by: LIPID MAPS Proteome Database is used by: Open PHACTS is related to: BRENDA is related to: ExplorEnz is related to: KEGG is related to: MetaCyc is related to: Nomenclature Committee of IUBMB is related to: Enzyme Nomenclature is related to: IntEnz- Integrated relational Enzyme database has parent organization: SIB Swiss Institute of Bioinformatics |
PMID:10592255 | Free, Available for download, Freely available | nif-0000-02803 | http://www.expasy.ch/enzyme/ | SCR_002487 | SciCrunch Registry | Enzyme nomenclature database | 2026-11-07 11:54:41 | 102 |
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