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https://pmlivingbiobank.uhnresearch.ca/

Core provides services for the use of Xenograft (PDX) models listed in open global catalogue of PDX models for comprehensive search and attribute filtering support for clinico-pathological and molecular data. Molecular data and visualization of profiled models could be accessed through the institute's portal.

Proper citation: University Health Network Princess Margaret Living PDX Core Facility (RRID:SCR_027523) Copy   

•   Source: SciCrunch Registry

https://www.mdanderson.org/saif

Core provides access to imaging instrumentation and expertise that is necessary to integrate advanced imaging technologies into basic and translational biomedical research. Services include Assistance in experimental design; Developing specialty equipment and innovative procedures for imaging; Preparing animals for studies, inducing and maintaining appropriate anesthesia and immobilization of animals during imaging;Processing and interpreting data for publication or grant preparation.

Proper citation: University of Texas MD Anderson Cancer Center Small Animal Imaging Facility (RRID:SCR_027643) Copy   

•   Source: SciCrunch Registry

https://www.pmgenomics.ca/pmgenomics/

Core is dedicated to providing access to cost-effective and high quality genomics services including standard and custom-tailored DNA sequencing using Illumina technologies, epigenomics, panel-based profiling (Luminex and Nanostring) and functional genomics. Single cell genomics applications on variety of popular platforms.

Proper citation: University Health Network Princess Margaret Genomics Centre PMGC Core Facility (RRID:SCR_027524) Copy   

•   Source: SciCrunch Registry

https://sites.ifi.unicamp.br/gate/gate-ats/criogenia-e-vacuo/

Core produces and supplies liquid helium and nitrogen to the entire IFGW academic community. Laboratory is equipped with helium liquefier from Linde and nitrogen liquefier from Stirling Cryogenics. In addition, it maintains complex support infrastructure essential for production and distribution of cryogenic liquids.

Proper citation: State University of Campinas Gleb Wataghin Physics Institute Criogenia/IFGW Core Facility (RRID:SCR_027638) Copy   

•   Source: SciCrunch Registry

https://pmlivingbiobank.uhnresearch.ca/

Core provides services for the use of patient-Derived tumor Organoid (PDO) model.Organoid models are derived from patient-derived xenograft tissues, primary tumors, and metastatic patient tissues. PMLB organoid repository includes models generated from colorectal, pancreatic, and lung cancer tissues.

Proper citation: University Health Network Princess Margaret Living Biobank PDO Core Facility (RRID:SCR_027530) Copy   

•   Source: SciCrunch Registry

https://bhpc.uhnresearch.ca/

Core provides services including Basic High-Throughput Sequencing Analysis, Advanced Data Analysis, High Performance Computing.

Proper citation: University Health Network Bioinformatics and High Performance Computing HPC Core Facility (RRID:SCR_027532) Copy   

•   Source: SciCrunch Registry

https://sttarr.ca/

Offers services to support studies in medical fields across oncology, cardiology, metabolic diseases, radiotheranostics and more.Helps with study design to final data analysis, including GLP-compliant histopathology services.

Proper citation: University Health Network Spatio-Temporal Targeting and Amplification of Radiation Response Core Facility (RRID:SCR_027531) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/advanced-technologies/mass-spectrometry.html

Core offers proteomics and metabolomics services. Provides support from experimental design to execution, sample processing, data interpretation, and assistance with presentations, manuscript preparation for publication and deposition of data in public repository and data storage on local server. Provides service analysis of post-translational modifications, such as phosphorylation, ubiquitination, acetylation, and others, with precise site localization on either single protein or for entire proteome.Uses Orbitrap Fusion Lumos coupled to Easy-nLC 1200 HPLC system. Facility instruments are operated with various acquisition methods, including classic Data Dependent Analysis (DDA) or more recent Data Independent Analysis (DIA). Acquired data from different methods are used to accurately identify and measure abundance of proteins and peptides employing different quantitation strategies: Label-free, TMT, pulsed-SILAC and Isotope-labelled Iodoacetamide (for Cysteine oxidation).Provides specialized data analysis software like MaxQuant and Mascot for DDA, Spectronaut for DIA of clinical samples and Perseus and Scaffold for data compilation, analysis, and dissemination.

Proper citation: Cancer Research UK Scotland Institute Mass Spectrometry Core Facility (RRID:SCR_027652) Copy   

•   Source: SciCrunch Registry

http://www.aomf.ca

Core offers services in optical microscopy experiments including: confocal, multiphoton, super-resolution, FRAP, FRET, live-cell timelapse, whole-slide scanning, image analysis and more.

Proper citation: University Health Network Advanced Optical Microscopy Core Facility (RRID:SCR_027535) Copy   

•   Source: SciCrunch Registry

https://kdtflow.uhnresearch.ca/

Core offers cell sorting and flow cytometry services. Provided instruments include BD FACS Canto II, Beckman Cytoflex LX, BD FACS ARIA III, AutoMacs Cell Separator.

Proper citation: University Health Network Krembil Discovery Tower Flow Cytometry Core Facility (RRID:SCR_027529) Copy   

•   Source: SciCrunch Registry

https://icahn.mssm.edu/research/resources/deans-cores/cryo

Cryo-Electron Microscopy Core facility at ISM offers EM services with state-of art instruments (Vitrobot for sample preparation, Glacios-2 TEM for imaging biological samples at atomic resolution). We offer single particle analysis (SPA) workflow, imaging drug delivery products (ex: liposomes, LNPs, AAVs..)

Proper citation: Icahn School of Medicine at Mount Sinai Mount Sinai Cryo-EM CoRE Core Facility (RRID:SCR_027649) Copy   

•   Source: SciCrunch Registry

https://chem.vt.edu/analyticalservices/crystallography.html

Core specializes in single-crystal structure determination of small molecules, inorganic materials, and minerals. The facility houses a Rigaku-Oxford Diffraction Synergy Single-Crystal X-ray Diffractometer equipped with both Cu and Mo sources, variable temperature capabilities (90 – 500 K) and the setup to perform high-pressure diamond-anvil studies.

Proper citation: Virginia Tech Crystallography Lab Core Facility (RRID:SCR_027620) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/divisions/public-health-sciences-division/research/collaborative-data-services.html

Core provides data-related support to cancer researchers by offering services like study design consultation, data management, programming, and access to patient data. Its purpose is to help researchers develop and execute studies, manage data, analyze results, and ultimately accelerate cancer research by making large, complex datasets more accessible and usable. CDS team uses evidence-based standards and effective quality assurance procedures from project design to study end. All CDS study staff are HIPAA-compliant and certified in Human Subjects and Good Clinic Practice training.

Proper citation: Fred Hutchinson Cancer Center Collaborative Data Services Core Facility (RRID:SCR_027586) Copy   

•   Source: SciCrunch Registry

https://chem.vt.edu/analyticalservices/chromatograhy.html

Facility enables complete qualitative and quantitative analysis of components within complex sample matrices. Provides services for separating mixtures, and supports critical research across numerous fields, including:Chemistry and Biochemistry, Biology and Medicine, Environmental Science and Toxicology, Food, Nutrition, and Pharmaceutical Development. Provides extraction, separation, detection, and quantification of organic and other complex mixtures from gas, solid, or liquid matrices.

Proper citation: Virginia Tech Department of Chemistry Chromatography Core Facility (RRID:SCR_027622) Copy   

•   Source: SciCrunch Registry

https://www.sharedfacilities.pitt.edu/wpqic

Core is equipped with suite of cryostats and measurement systems for probing electrical, magnetic, and quantum properties at cryogenic temperatures. Sample preparation capabilities include tools for wafer processing, nanomaterial transfer, and inert atmosphere handling. Deposition systems support thin film growth and surface treatment using a variety of techniques. Wirebonding and related sample preparation tools enable precise device packaging and integration, supporting a broad range of experimental workflows in quantum and nanoscale science.

Proper citation: University of Pittsburgh Western Pennsylvania Quantum Information Core Facility (RRID:SCR_027582) Copy   

•   Source: SciCrunch Registry

https://www.bwhneurosciences.org/neurotechnology-studio/

Offers advanced instrumentation and expert support to advance understanding of brain function and brain disease by providing researchers with access to cutting-edge technologies. Provides access to advanced instrumentation for optical microscopy, genomics, metabolic imaging and other technologies, as well as image analysis software. Provides expert support and training, data quality and interpretation.

Proper citation: Brigham and Women’s Hospital NeuroTechnology Studio Core Facility (RRID:SCR_027687) Copy   

•   Source: SciCrunch Registry

https://www.uc.pt/viravector/

Portuguese national research infrastructure which provides expert consultation for the safe and effective use of vector technologies, and offers custom design and production services for multiple viral types to the national research community and other stakeholders.

Proper citation: University of Coimbra ViralVector Core Facility (RRID:SCR_027689) Copy   

•   Source: SciCrunch Registry

https://www.lsuhs.edu/centers/center-for-post-transcriptional-regulation/research-cores

Metabolomics and Machine Learning Core provides metabolite profiling and stable-isotope tracing, molecular modeling, and machine learning to integrate datasets across transcriptomic, proteomic, and metabolomic analysis.

Proper citation: Louisiana State University Health Sciences Center Shreveport Metabolomics and Machine Learning Core Facility (RRID:SCR_027717) Copy   

•   Source: SciCrunch Registry

https://icahn.mssm.edu/research/resources/deans-cores/flow-cytometry

Situated within the Icahn School of Medicine at Mount Sinai, our CoRE provides all members of the Mount Sinai Health System community with the instrumentation, expertise, and education required to incorporate flow cytometry and cell sorting into any research project.

Proper citation: Icahn School of Medicine at Mount Sinai Flow Cytometry CoRE Core Facility (RRID:SCR_027701) Copy   

•   Source: SciCrunch Registry

https://ccg.uni-koeln.de/

Represents central facility and does not operate for profit, engaging in academic research collaborations and service provision on collaborative basis. Provides infrastructure for all kinds of sequencing, gene mapping and whole genome association studies in complex diseases as well as the validation of copy number variations.

Proper citation: University of Cologne Center for Genomics (CCG) Core Facility (RRID:SCR_027822) Copy   

•   Source: SciCrunch Registry