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https://www.genomics.pitt.edu/

Core is CAP/CLIA-certified facility offering comprehensive next generation sequencing (NGS) and bioinformatics services. Supports flexible workflows from nucleic acid extraction and library preparation to sequencing and custom data analysis. Services include DNA/RNA extraction, quality checks, various types of RNA/DNA library prep, NGS, methylation, proteomics (Illumina IPP), metabolomics, lipidomics, pharmacogenomics, and microarray analysis, with options for end-to-end or modular support. Advanced instrumentation includes Illumina NovaSeq X Plus and 6000 platforms, MiSeqDX, Hamilton , Eppendorf, and Tecan liquid handlers, automated extraction systems, and more. HTGC also provides clinical-grade sequencing.

Proper citation: University of Pittsburgh Health Sciences High Throughput Genomics Core Facility (RRID:SCR_028184) Copy   

•   Source: SciCrunch Registry

https://www.cruk.cam.ac.uk/core-facilities/histopathology/

Core facilitates all aspects of histopathology including processing, embedding, sectioning, histochemical staining, tissue microarray building, immunohistochemistry, in situ hybridisation, whole slide scanning, and image analysis.

Proper citation: Cancer Research UK Cambridge Institute Histopathology and In Situ Hybridisation Core Facility (RRID:SCR_028183) Copy   

•   Source: SciCrunch Registry

https://www.rushu.rush.edu/research-rush-university/rush-core-laboratories/rush-research-bioinformatics-core

Core empowers researchers from genomic, clinical, and basic sciences disciplines at Rush and beyond with cutting-edge bioinformatics resources. Provides guided data analysis and hypothesis-driven research, large-scale data analysis, analytical plan development and results interpretation, algorithm and script development for custom data processing. Provides innovative infrastructure tools, including the Research Private Cloud and scalable cloud-based solutions. Services include customized analytical solutions, data storage and management workflows, training and support for bioinformatics tools.

Proper citation: Rush University Research Bioinformatics Core Facility (RRID:SCR_028185) Copy   

•   Source: SciCrunch Registry

https://www.ou.edu/structuralbiology/cobre-core-facilities/ppc

Offers access to instrumentation, training, and services for protein expression, purification, and biophysical characterization. In addition to instrument access, PPCC personnel offer advice, hands-on training, education, and collaboration. Provides a range of protein purification and characterization equipment.

Proper citation: University of Oklahoma Protein Production and Characterization Core Facility (RRID:SCR_028067) Copy   

•   Source: SciCrunch Registry

https://icv.institutducerveau.org/service/icv-vectorologie/

Vectorology Core Facility (part of the Cellular Engineering and Vectorology platform) provides specialized, high-level expertise, tools, and services for designing, producing, and validating viral vectors used in neuroscience research and gene therapy development. It supports academic and industrial partners by generating modified, safe viral vectors (e.g., AAV, lentivirus) for gene transfer and cellular, including human iPS, engineering.

Proper citation: Paris Brain Institute Vectorology Core Facility (RRID:SCR_028066) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/research-centers/neurosciences/core-services

Core provides access to cost effective instrumentation, software, and scientific consultation. First-come first-serve, fee-for-service core facility with fulltime staff to help users generate rigorous scientific data. Offers two point-scanning confocal microscopes, Nikon A1R and Zeiss LSM900, LSRFortessa X-20 and MACSQuant 10 analytic flow cytometers and 4 laser Sony MA900 cell sorter.

Proper citation: Indiana University School of Medicine Stark Neurosciences Research Institute Flow Cytometry and Microscopy Core Facility (SNRI-FCMCF) (RRID:SCR_028155) Copy   

•   Source: SciCrunch Registry

https://rtsf.natsci.msu.edu/transgenics-crispr/index.aspx

Provides comprehensive CRISPR genome editing and transgenic services for animal models and stem cells, with both end-to-end and modular support for model generation. The core also offers full cryopreservation and cryorecovery services, plus rederivation, import/export assistance, genotyping support, and consultation in genome engineering and reproductive biology.

Proper citation: Michigan State University Transgenic and Genome Editing Core Facility (RRID:SCR_028154) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/advanced-tissue-imaging-shared-resource

Core offers streamlined, multiplexed tissue analysis services including tissue sectioning, staining, imaging, spatial RNA sequencing, analysis and interpretation of results.

Proper citation: Roswell Park Comprehensive Cancer Center Advanced Tissue Imaging Shared Resource ATISR Core Facility (RRID:SCR_028378) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/biorepository-laboratory-services

Core is comprehensive data and biospecimen bank (malignant and normal tissue and their derivatives, blood and bone marrow) for research along with a range of services that accompany biospecimens. Facilitates access to human tissue, blood and bone marrow for investigators with Institutional Review Board (IRB) approved protocols emphasizing translational research. Helps investigators to establish Biospecimen and Data Research (BDR) protocols and supports the submission of grants by providing feasibility analysis, cost estimates and letters of support.

Proper citation: Roswell Park Comprehensive Cancer Center Biorepository and Laboratory Services Shared Resource BLS Core Facility (RRID:SCR_028376) Copy   

•   Source: SciCrunch Registry

https://biotech.rpi.edu/core-facilities/proteomics

Facility provides mass spectrometry-based analytical support.Houses multiple mass spectrometry platforms with complementary ionization capabilities, including EI, APCI, ESI, and MALDI, enabling qualitative and quantitative analysis of diverse sample types across a range of volatility, polarity, and molecular weight. Several systems are coupled with chromatographic separation platforms, allowing complex mixtures to be separated prior to mass spectrometric analysis. Supports research in areas including proteomics, small-molecule analysis, carbohydrate and glycosaminoglycan-related analysis, metabolomics-oriented method development, and drug-discovery-related projects.Particular strength of the Core is the analysis of complex biomolecules, including proteins, peptides, carbohydrates, and heparin/glycosaminoglycan-related samples. The Core works closely with investigators to evaluate feasibility, develop appropriate workflows, and interpret mass spectrometry data in the context of each project.

Proper citation: Rensselaer Polytechnic Institute RPI-Proteomics Core Facility (RRID:SCR_028377) Copy   

•   Source: SciCrunch Registry

https://umaine.edu/core/dna-sequencing/

DNA Sequencing facility provides Sanger sequencing and other services to labs on campus and beyond. Users can choose the degree of in-house processing to accommodate individual needs, providing flexibility for clients of all levels.

Proper citation: University of Maine DNA Sequencing Facility (RRID:SCR_028250) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/biostatistics-statistical-genomics

Core offers services in design, oversight, implementation, analysis, publication, and reporting of scientific studies including articulating study objectives and hypotheses, grant writing, conceiving appropriate cost-effective designs and models for achievement of study objectives, monitoring interim and final analyses, and co-authoring abstracts and manuscripts.

Proper citation: Roswell Park Comprehensive Cancer Center Biostatistics and Statistical Genomics Shared Resource BSGSR Core Facility (RRID:SCR_028371) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/gmp

Core provides clean rooms, cell therapy equipment, manufacturing know-how, capabilities and comprehensive suite of quality assurance and control procedures.

Proper citation: Roswell Park Comprehensive Cancer Center GMP Engineering and Cell Manufacturing Core Facility (RRID:SCR_028373) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/tnc

Core provides services primarily on animal models to enable preclinical testing and translational research, accelerating the development of human neurological therapies. It specializes in neurosurgical procedures in rodents and large animals, specializing in gene/stem cell therapy and device testing.

Proper citation: Emory University Translational Neuroscience Core Facility (RRID:SCR_028301) Copy   

•   Source: SciCrunch Registry

https://www.roswellpark.org/shared-resources/comparative-oncology

Core offers services for preclinical models including barrier facilities with fully automated environmental controls for the housing of research models. Specialized husbandry with trained staff who perform all manipulations inside Biosafety cabinets for maintenance of a pathogen-free environment for models held in micro isolation (MI) housing systems. In addition to housing pre-clinical models in state-of-the-art facilities, COSR provides Specialized Surgical Services and procedural training, consultation in experimental design, irradiation services, in-house hematological testing, genotyping services, design and conduct of pre-clinical toxicological studies.

Proper citation: Roswell Park Comprehensive Cancer Center Comparative Oncology Shared Resource COSR Core Facility (RRID:SCR_028389) Copy   

•   Source: SciCrunch Registry

https://www.pediatrics.pitt.edu/pediatric-clinical-research-services

Core is responsible for overall clinical research management for studies engaging a pediatric population, both grant funded and industry sponsored clinical and translational research studies. For both Children Hospital of Pittsburgh and Magee-Women Hospital, the PCRS group provides comprehensive study engagement and helps investigators enroll research subjects. Services are available in two areas, allowing the group to best meet the needs of Pitt physicians and the patients they serve.

Proper citation: University of Pittsburgh Pediatric Clinical Research Services PCRS Core Facility (RRID:SCR_028302) Copy   

•   Source: SciCrunch Registry

https://www.fredhutch.org/en/research/divisions/translational-science-and-therapeutics-division/translational-pathology.html

Core provides high-plex immunohistochemistry (PhenoCycler/CODEX) on human and mouse FFPE tissues, image analysis (IHC, mIHC, high-plex), and support for collaborative and fee-for-service projects.

Proper citation: Fred Hutch Cancer Center Translational Pathology Core Facility (RRID:SCR_028306) Copy   

•   Source: SciCrunch Registry

https://nrf.aux.eng.ufl.edu/

Core supports and enhance research and education by providing access to characterization and process instrumentation. Expert staff provides the assistance and guidance necessary so that students, faculty, and industry get the most effective and appropriate use of facility resources. NRF facilities encompass 100+ instruments, tools and techniques as well as a 7,000 sq. ft. Class 100-1000 Cleanroom facility. Facilities also include instrumentation that allows characterization of radioactive samples.

Proper citation: University of Florida Nanoscale Research Facility NRF Core Facility (RRID:SCR_028304) Copy   

•   Source: SciCrunch Registry

https://research.manchester.ac.uk/en/equipments/biomolecular-nmr-facility/

Core provides advanced NMR spectroscopy for researching the atomic-level structure, dynamics, and interactions of biological macromolecules. It supports structural biology, biocatalysis, and drug discovery by analyzing proteins, DNA, RNA, and carbohydrates. Includes 800MHz NMR spectrometer with H/F-C-N Cryoprobe.

Proper citation: University of Manchester Biomolecular NMR Core Facility (RRID:SCR_028357) Copy   

•   Source: SciCrunch Registry

https://www.ucl.ac.uk/biosciences/research/research-facilities/molecular-biology/biosciences-anatomy-building-molecular-biology-unit

Facility contains equipment for all basic molecular biology needs. Training and help are provided. Provides molecular biology services ranging from DNA preparations to cloning and mutagenesis projects.

Proper citation: University College London Molecular Biology Core Facility (RRID:SCR_028350) Copy   

•   Source: SciCrunch Registry