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http://eagle-i.itmat.upenn.edu/i/00000138-ba32-e90b-9cd7-d7e280000000

Core facility that provides the following services: Illumina sequencing service, 5500xl sequencing service. The recent boon in high-throughput sequencing technologies has offered enormous potential to applications in genome sequencing, transcriptome profiling, epigenetics, metagenomics, discovery of non-coding RNAs and protein binding sites. A primary mission of PGFI is to lead the development of new genomics technologies at the University of Pennsylvania. In response to the ever growing demand for high-throughput sequencing at Penn, PGFI?s HTS facility was established. In this facility, investigators have access to different types of HTS technology: Illumina?s HiSeq and Applied Biosystem?s SOLiD4 and 5500xl. With two HiSeqs, the facility can provide the latest innovation from Illumina featuring up to 3 billion paired-end reads (up to 100x100 bp reads) per flow cell, 8 lanes per flow cell and 2 flow cells per machine. With the SOLiD4, the facility can provide up to 1.4 billion reads per slide, 50 x 25 bp paired-end reads, up to 8 sectors per slide and 2 flow cells per machine. With the 5500xl, the facility can provide up to 180 Gb or more than 2.8 B reads per run. The 5500xl offers 75 bp fragment runs, 75x35 bp paired-end runs and up to 60 bp x 60 bp mate paired runs with the added bonus of pay-as-you-go sequencing. All platforms offer multiplexing capability. Currently Illumina offers 48 barcodes and Life Technologies offers 96 barcodes. The SOLiD 4 system provides greater than 99.94% accuracy due to 2-base encoding. The 5500xl offers up to 99.99% accuracy utilizing 2-base encoding and Exact Call Chemistry.

Proper citation: Penn High-Throughput Sequencing Facility (RRID:SCR_010015) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-e7cd-3f54-eb5b-b63c80000000

Core facility that provides the following services: Immunohistochemistry (IHC) staining service, Tissue processing and sectioning service, Staining service. The Histology and Gene Expression Core Facility provides expert professional services for members of the Cardiovascular Institute. Services for non- Institute investigators are available on a fee-for-service basis as time permits. The Histology and Gene Expression Core offers all histology-related services include tissue processing, embedding, sectioning, staining, immunocytochemistry and InSitu Hybridization.

Proper citation: Penn Histology and Gene Expression Core (RRID:SCR_010017) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-ba97-298d-9cd7-d7e280000000

Core facility that provides the following services: ELISA AND ELISpot assays, Multi-color flow cytometry immunophenotyping and proliferation assays, Luminex multiplex and Cytometric Bead immunological assays, Peripheral blood mononuclear cell isolation, Intraepithelial lymphocyte isolation from intestinal biopsy, Cryopreservation, Immunological assay training. The Human Immunology Core will provide expertise and instrumentation for the analysis of immune function in patients during treatment with anticancer drugs and immunotherapy. The Core will serve as a central facility for incorporating the newest technologies and performing validated immunology assays for phase I/II clinical studies, while also offering expert scientific and technical consultations to users interested in conducting this kind of innovative research.

Proper citation: Penn Human Immunology Core (RRID:SCR_010018) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000139-5064-ad11-4778-6c3080000000

Core facility that provides the following services: Mass spectrometer access. The Mass Spectrometry Facility is part of the Shared Instrument Facilities of the Department of Chemistry. It provides low and high resolution mass spectra to Penn Chemistry and to other research groups throughout the university community for the determination of elemental composition and purity of a wide variety of compounds. Investigators interested in using the facility are encouraged to call and discuss their project. Usage fees will be quoted at this time. Fees depend upon the instrument involved in the analysis, complexity of the project, training, etc.

Proper citation: Penn Mass Spectrometry Facility (RRID:SCR_010021) Copy   

•   Source: SciCrunch Registry

https://www.bioinformatics.upenn.edu/

Core facility that provides the following services: Desktop sequence analysis tools subscription, Database and web applications support, Genomic-scale sequencing analysis, Sequence analysis application support, Transcript profiling consultation service, Transcript profiling application support, Transcript profiling data analysis, Automating large or repetitive tasks, Web space for biological databases, Bioinformatics/genomics resource identification, and Data storage. The bioinformatics staff of the Penn Molecular Profiling Facility is available to provide experimental design and analytical services to users of the Facility and the basic and biomedical research community. Additional services are provided, including grant support, data management and custom computational projects. This facility provides one-on-one training and hosts instructional workshops. Their goal is to ensure that scientists across the University are able to exploit existing and emerging computational technologies, especially related to their genomics scale datasets.

Proper citation: University of Pennsylvania Molecular Profiling Facility Bioinformatics (RRID:SCR_010022) Copy   

•   Source: SciCrunch Registry

http://alaska.eagle-i.net/i/0000012a-2506-fb41-a68e-378080000000

Core facility that provides the following services: Data storage service, Confidentiality assistance service, Data entry service, Data importing service, Data extraction and monitoring service, ID linkage and tracking service, Quality control services, Database development and maintenance service. The EBC staff provide support for CANHR research projects in all data-related activities, including data entry, the development and management of databases, and generation of data related to field visits, analyses, and research proposals. It provides expertise in statistical and epidemiologic issues and is responsible for training seminars on the preparation of grants and publications.

Proper citation: UAF Epidemiology and Biostatistics Core Laboratory (RRID:SCR_010069) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000136-ad2d-0008-a53f-a15a80000000

Core facility that provides the following services: Free movement behavioral testing data acquisition and analysis service, Small animal vital sign evaluation. The Behavioral Testing Facility was created to facilitate the development of neuroscience research at the Universidad Central del Caribe recognizing the importance of behavioral testing. The facility has two mayor components: A) the equipment infrastructure and B) the technical support division. The facility offers equipment for remote behavior visualization (RBV).

Proper citation: UCC Behavioral Testing Facility (RRID:SCR_010072) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000135-c95d-a6f3-a272-8ee780000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 26,2026. Core facility that provides the following services: Research support, Research Training. The DMSRSU provides study design, data management, quality assurance, and statistical analysis support for UCC researchers. The DMSRSU has a strong infrastructure which includes the following subunits: Data Abstraction and Management; Data Entry; Quality Control; Data Analysis and Consultant; and Administrative and Computer Systems. Each of these subunits consists of experienced professionals readily available to assist researchers and to provide data management and statistical research support to investigators. In addition, the DMSRSU counts on a highly experienced and reliable consulting team.

Proper citation: UCC Data Management and Statistical Research Support Unit (RRID:SCR_010074) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012a-2510-c9ec-c99c-aef680000000

Core facility that provides the following services: Cell cycle analysis with live or dead cells, Apoptosis analysis service, Calcium flux analysis service, Cell population isolation service. The of the goal of the Immunology Core of MCI, which functions as a fee-for-service facility, is to provide the Hawaii community with a service-oriented facility to meet the needs in the FACS research areas. We are equipped with BD FACSAria, BD FACSCalibur, GuavaEAsyCytePlus, Luminex 200, Beckman-Coulter ViCell, CTL-ImmunoSpot�� S5 Core Analyzer, Bio-Rad and BioTek ELx808 ELISA readers and washers, Faxitron compact 43855D x-ray irradiation system, and Faxitron x-ray CP160 for in vivo animal work.

Proper citation: UH Manoa COBRE Molecular and Cellular Immunology Core (RRID:SCR_010075) Copy   

•   Source: SciCrunch Registry

http://alaska.eagle-i.net/i/0000012a-2507-5cac-a68e-378080000000

Core facility that provides the following services: Data quality control and management service. The Nutrition and Physical Activity Core supports multidisciplinary research requiring dietary and/or physical activity assessment, as well as provide nutritional sciences expertise. The NPA Core offers a range of services including high-quality dietary assessment, active collaboration in the design, implementation, and analysis of nutrition-related research. In addition to supporting the needs of CAHNR projects, the NPA Core will also actively promote and foster new research programs investigating the diet of Alaska Natives.

Proper citation: UAF Nutrition and Physical Activity Core (RRID:SCR_010070) Copy   

•   Source: SciCrunch Registry

http://alaska.eagle-i.net/i/0000012a-2507-70de-a68e-378080000000

The primary research of the laboratory aims at understanding the role of Rho-subfamily small GTPases, in particular Rac1A, as pivotal regulators of actin filament dynamics and redox homeostasis in central nervous system (CNS) neurons. A second project addresses neuronal stem cells and their generation, functional integration, and elimination in the adult male wild songbird Junco hyemalis.

Proper citation: UAF Optical and Tissue Culture Core (RRID:SCR_010071) Copy   

•   Source: SciCrunch Registry

http://hawaii.eagle-i.net/i/0000012b-36b7-8cc7-2f73-b43980000000

Core facility that provides the following services: ELISA-based assay service, Luminex based ELISA assay service, Coenzyme Q10 in plasma analysis by HPLC/ECD (oxidized, reduced and total Q10), DNA analysis by HPLC, Phenolic agents from plasma, urine, breast milk, foods analysis by LC/MSMS, Lipid-phase micronutrients in plasma or foods analysis by HPLC/PDA/FD (12 carotenoids, 2 retinoids, 3 tocopherols), Metabolomics analysis by LCMS, Vitamin A and pro-vitamin A in plasma analysis by HPLC/PDA, Vitamin C in plasma, food analysis by HPLC/ECD or PDA, Vitamin D in plasma analysis by LC/MSMS, Vitamin E in plasma analysis by NP-HPLC/PDA/FD (all tocopherols), Vitamin K analysis by LC/MSMS. The Analytical Biochemistry resource was established to support and facilitate collaborative cancer research between the various disciplines at the Center by providing chemical analyses which contribute to understanding chronic diseases in our population. It also assists in the determination of the nature or structure of biological molecules as well as the quantification of those compounds. The facility is equipped with essential instruments needed to perform analytical chemistry, and modern, state-of-the-art technology for difficult-to-measure and ultra-low concentrated compounds.

Proper citation: UH Manoa Analytical Biochemistry Shared Resource (RRID:SCR_010085) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7c77-053b-fbab-3b8480000000

Core facility that provides the following services: Tissue processing and paraffin embedding, Cell processing and paraffin embedding, Cryosectioning service, Paraffin-embedded sectioning, Hematoxylin and eosin staining, Immuno-staining (IHC) of tissue sections, Histological staining service. The Cancer Histology Core is a non-profit, research-oriented resource core supported by the Abramson Cancer Center. It offers all histology-related services to all members of the Abramson Cancer Center with high quality, low cost, fast turnout, and easy interaction. Service will be open to all life sciences investigators at Penn, but priority will be given to full members of the Abramson Cancer Center.

Proper citation: Penn Cancer Histology Core (RRID:SCR_010001) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/00000138-7bcc-1f66-fbab-3b8480000000

Core facility that provides the following services: Antibody screening by ELISA, Cell Culture Training, Production and Purification of Antibodies from Hybridoma Lines, Endotoxin Testing, EBV Transformation, Special media production, Liquid N2 storage, Freezing Cells. Cell Center Services Facility is the service component of the Cell Center, provides training and services in various cell culture and associated procedures including Mycoplasma and Endotoxin testing. The cell culture service includes cell culture at various scales, large scale growth of hybridoma and other cell lines followed by antibody purification by protein G column and the generation of lymphoblastoid cell lines by EBV induced transformation of lymphocytes. In addition, the facility prepares specialized cell culture media, drosophila media, and various molecular biological reagents. Recently cell transfection and selection service has been introduced at the facility.

Proper citation: Penn Cell Center Services Facility (RRID:SCR_010002) Copy   

•   Source: SciCrunch Registry

http://uccaribe.eagle-i.net/i/00000137-035f-9eba-a53f-a15a80000000

Core facility that provides the following services: Image acquisition training. The TEM laboratory provides access to ultrastructural analysis of biological specimens via a Jeol 100 CX transmission electron microscope. The TEM is equipped with AMT 4 MP digital camera to facilitate image acquisition and 3D reconstruction from serial sections. In addition, to conventional EM procedures of in situ and cell culture specimens the laboratory also offers imunnogold labeling and the visualization of fluorescent dyes after photoconversion.

Proper citation: UCC Transmission Electron Microscopy Laboratory (RRID:SCR_010081) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000138-7bdf-33f8-480b-864680000000

This core has several components. The DNA bank receives specimens from various studies, extracts DNA, and provides storage. Quality control, organization, and efficiency are critical. Genotyping services provide the necessary speed, efficiency, and accuracy to perform genomic screens (with standard markers) in as little time as possible.

Proper citation: Vanderbilt DNA Resources Core (RRID:SCR_010176) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000139-c63d-d3da-b341-4bb480000000

The purpose of the Vanderbilt Clinical Research Center is to provide the resources needed by clinical and translational investigators to carry out their research in an environment optimized for safety, comfort and convenience of the patient or volunteer, with the facilities and expertise to provide the most advantageous milieu in which to address the investigator''s experimental requirements. This includes outpatient space, inpatient beds, laboratories, equipment and supplies for clinical research by the faculty of Vanderbilt University, Meharry Medical College, and their collaborating investigators. The use of the center is justified on the basis of the quality and significance of the research and the special need for the Center''s facilities.

Proper citation: Vanderbilt Clinical Research Center (RRID:SCR_010170) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000138-e822-c8d3-dacb-da6080000000

Ascertainment for genetic studies is a crucial and labor-intensive effort. The Genetic Studies Ascertainment Core offers a variety of services to Vanderbilt clinical and basic researchers interested in or currently conducting research involving genetic analysis of complex disorders. We can aid in the development and coordination of individual and family based genetic studies. The faculty and staff have expertise in the issues that need to be considered when setting up a genetic study and are qualified to discuss with individuals issues that might be raised by participation in a genetic study. We can provide services for you or assist you in developing your own program. Study consultations are available to determine cost, time, and personnel needs as well as the best method of ascertainment for your project.

Proper citation: Vanderbilt Genetic Studies Ascertainment Core (RRID:SCR_010179) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000138-7ba8-f7ee-480b-864680000000

VIIBRE''s Automated Biosystems Core (VIIBRE-ABC) provides a powerful technical foundation for the study of dynamic cellular metabolism, signaling, and control, with more than $4.7 million received from the Defense Threat Reduction Agency (DTRA), the National Institute on Drug Abuse (NIDA), the NIH Shared Instrumentation Program, and Vanderbilt University. An important focus of this effort is to explore dynamic host responses to chemical agents, toxins, and microbial pathogens. The ABC comprises two major instruments: a custom Omni-Omics system built around a Waters Synapt G2 UPLC/GC/ESI/nESI Ion Mobility-Mass Spectrometer, and a microfluidics-enabled high-content screening system built around a Perkin Elmer Opera QEHS Automated Confocal Microscopy System.

Proper citation: Vanderbilt Institute for Integrative Biosystems Research and Education Automated Biosystems Core Laboratory (RRID:SCR_010184) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000138-7bb9-c509-480b-864680000000

Core facility that provides the following services: Photolithography Laboratory, Device Fabrication Laboratory, VIIBRE Machine Shop, VIIBRE Electronics Shop. The VIIBRE Microfabrication Core offers facilities and expertise for the design, manufacture, and implementation of micro- and small-scale electronic, mechanical and fluidic devices. Typical products include fluidic networks,pumps and valves, arrays of microfabricated traps for cellular study, implantable devices for in vivo imaging, liquid and gas control systems, biological habitats, environments and microbioreactors, and more.

Proper citation: Vanderbilt Institute for Integrative Biosystems Research and Education Microfabrication Core (RRID:SCR_010186) Copy   

•   Source: SciCrunch Registry