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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.waters.com/waters/en_US/1525-Binary-HPLC-Pump/nav.htm?cid=534310&locale=en_US
Itegrated, high-pressure, binary HPLC pump that feature on-board pulse dampening and efficient mixing. Their pulse-free solvent flow, from analytical to semi-preparative flow rates, makes them best for use with highly sensitive detectors. Designed for use with 2 to 4.6 mm I.D. columns in routine LC and LC/MS applications, these pumps have a programmable flow-rate range of 0.00 to 10.00 mL/min in 0.01 mL increments.
Proper citation: Waters: 1525 Binary HPLC Pump (RRID:SCR_020875) Copy
https://www.waters.com/webassets/cms/support/docs/71500023202rc.pdf
Waters 2996 PDA Detector can be used for in-vitro diagnostic testing to analyze many compounds, including diagnostic indicators and therapeutically monitored compounds. It also describes detector optics and the principles of Spectral Contrast used in the Millennium32 software for analyzing the data from the PDA detector.
Proper citation: Waters: 2996 Photodiode Array Detector (RRID:SCR_020876) Copy
https://mobile.labwrench.com/equipment/22026/zeiss/axioplan-microscope-system
Upright microscopy imaging platform for complex research that is optimized for light transmission and extremely high contrast fluorescence imaging. This complete system comes fully configured for best performance, range and functionality.
Proper citation: Zeiss: Axioplan 2 imaginig system (RRID:SCR_020918) Copy
Light sheet fluorescence microscope for the imaging of large cleared specimens. Lightsheet Z.1 with Clr Plan-Apochromat 20x/1.0 Corr nd=1.38 is used to perform experiments with tissue cleared by Scale medium (Hama et al, Nat Neurosci. 2011), which has a refractive index of n=1.38.
Proper citation: Zeiss: Lightsheet Z.1 Fluorescence Microscope (RRID:SCR_020919) Copy
Visible confocal microscope that acquires the X dimension simultaneously on a line CCD detector while scanning only in the Y dimension. This allows users to increase the speed of image acquisition compared to traditional confocal systems. This system is equipped with two fluorescence detectors and 4 lasers lines at 405nm, 488nm, 561nm and 633nm. It is capable of scanning over 120 FPS for a large field of view.
Proper citation: Zeiss: 5-Live (RRID:SCR_020916) Copy
https://mobile.labwrench.com/equipment/13553/zeiss/auriga-laser
Electron microscope with pulsed laser beam that creates images in high resolution in the nanometre range. This miscroscope allows the user to investigate your samples with X-ray analysis, rework interesting sample positions, and analyze non-conducting material and complex geometries.
Proper citation: Zeiss: Auriga Auriga (RRID:SCR_020914) Copy
https://gitlab.com/PAM-PIE/PAM
Software package for quantitative analysis of fluorescence microscopy and spectroscopy data, with focus on experiments using pulsed interleaved excitation. Open source software package written in MATLAB that offers workflow through its graphical user interface. Framework for integrated analysis of imaging, single-molecule, and ensemble fluorescence data.Supports most types of data collection modalities.
Proper citation: PAM (RRID:SCR_020966) Copy
https://www.olympus-ims.com/en/metrology/ols4100/
Laser scanning digital microscope for non-contact 3D observations and measurements of surface features at 10 nanometer resolutions with fast image acquisition and high-resolution images over wider area. Z-drive moves in steps less than 1nm, accuracy and repeatability guaranteed by Olympus. The system includes 5 objectives: 5x/0.15, 10x/0.30, 20x/0.60, 50x/0.95, and 100x/0.95.
Proper citation: Olympus: LEXT OLS4100 laser confocal microscope (RRID:SCR_020969) Copy
Refirgerated/heated bath circulator that delivers high heating and cooling capacities for rapid heat-up and cool-down times and has electrical requirements of 208/230 V 60 Hz
Proper citation: Thermo Fisher: Ultra-low Temp G50 AC150 208-230 VOLT 60HZ; Refrigerated/Heated Bath Circulator (RRID:SCR_020855) Copy
Refrigerated bath recirculators that is designed for circulating to external applications and has a temperature range of --80�C to +10�C
Proper citation: Thermo Fisher: ULT 180104201600; Bath Recirculator (RRID:SCR_020856) Copy
Recirculating chiller that provides reliable temperature control with a temperature range from -5�C to +90�C
Proper citation: Thermo Fisher: ThermoFlex 5000; Recirculating Chiller (RRID:SCR_020854) Copy
https://www.cityofhope.org/research/beckman-research-institute
Not-for-profit medical research facility located at and partnering with the City of Hope National Medical Center in Duarte, CA, United States.Fields of research include Cancer, Diabetes, Metabolic disorder, HIV/AIDS.
Proper citation: Beckman Research Institute of City of Hope (RRID:SCR_020975) Copy
https://www.miltenyibiotec.com/products/macs-flow-cytometry/software/flowlogic-software.html
Software tool for flow cytometry data analysis by Miltenyi Biotec.
Proper citation: Flowlogic (RRID:SCR_020942) Copy
https://guoweilong.github.io/BS_Seeker2/index.html
Software tool as versatile aligning pipeline for bisulfite sequencing data. Used for mapping bisulfite sequencing data and generating DNA methylomes. Improves mappability over existing aligners by using local alignment. Maps reads from RRBS library by building special indexes with improved efficiency and accuracy. Provides additional function for filtering out reads with incomplete bisulfite conversion, which is useful in minimizing overestimation of DNA methylation levels.
Proper citation: Bs-Seeker2 (RRID:SCR_020948) Copy
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3001096/
Software pipeline to identify MITEs as well as other small Class 2 non autonomous Transposable Elements from genomic DNA data sets. Used for discovering miniature inverted repeat transposable elements from genomic sequences. Can search large genomic data sets including whole genome sequences.
Proper citation: MITE-Hunter (RRID:SCR_020946) Copy
Software package for DNA methylation analysis. Used for context-wise, gene-wise, bin-wise, region-wise and sample-wise analysis and visualizations. Used to improve precision of heterozygous SNV calls and supports allele-specific methylation detection and visualization in bisulfite-sequencing data.
Proper citation: cgmapotools (RRID:SCR_020950) Copy
Portal to build, train and deploy state of the art models powered by reference open source in natural language processing.
Proper citation: Hugging Face (RRID:SCR_020958) Copy
https://github.com/Niinleslie/MesKit
Software R package for dissecting cancer evolution from multi region derived tumor biopsies via somatic mutations. Used for characterizing cancer genomic ITH and inferring history of tumor evolution via implementation of well established computational and statistical methods.
Proper citation: MesKit (RRID:SCR_020959) Copy
https://resources.revvity.com/pdfs/tch-opera-phenix-plus-improved-3d-imaging.pdf
Opera Phenix Plus system for high throughput high content assays, phenotypic screening, assays using complex disease models, such as live cells, primary cells and microtissues, and fast response assays like calcium flux or cardiomyocyte beating.Optical design lets you generate information through confocal imaging and at higher throughput through simultaneous acquisition. Delivers speed without compromising sensitivity. Uses Harmony High Content Imaging and Analysis Software to quantify complex cellular phenotypes. Harmony software is designed for PerkinElmer high content screening systems.
Proper citation: Perkin Elmer: Opera Phenix Plus High Content Screening System (RRID:SCR_021100) Copy
https://www.microscope.healthcare.nikon.com/en_EU/products/inverted-microscopes/eclipse-ti2-series
Inverted microscope delivers unparalleled 25mm field of view. With this FOV, the Ti2 maximizes sensor area of large format CMOS cameras without making compromises, and significantly improves data throughput. Stable, drift free platform designed to meet demands of super resolution imaging with high speed imaging applications. Status of each sensor is automatically recorded during acquisition, providing quality control for imaging experiments and enhancing data reproducibility.
Proper citation: Nikon: ECLIPSE Ti2 inverted microscope (RRID:SCR_021068) Copy
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