Tools   Select Another Resource Report Type

http://eagle-i.itmat.upenn.edu/i/0000013f-8b15-e20f-a468-831a80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024.Core facility that provides the following services: Tissue culture suite access, Biological assay development for screening experiments, High-throughput-screening service, Post-screening studies. The Wistar Molecular Screening Facility is a shared resource facility open to Wistar and non-Wistar scientists. The laboratory operates on a fee-for-service basis, providing expertise in bridging automated technology with the development of innovative, robust biochemical or cell-based assays for high-throughput chemical and functional genomic screens. The laboratory strives to possess the flexibility to accommodate diverse biological systems and a variety of investigator-developed assay types. While service is the primary role of the laboratory, the staff will also develop and implement new technology as needed to fulfill the needs of its users. Education and training is also part of the laboratory''s mission, as trainees apply high-throughput screening experiments to their investigations. The ultimate goal of the laboratory is to enable scientists to apply cutting edge technology and unique resources to discover agents (i.e. small molecules, siRNA) to further study the functions of poorly understood proteins, signaling pathways, and cells in complex biological process relevant to human physiology and disease. The combinations of these activities will provide scientists opportunities to develop new innovative basic and translational research, preliminary data for hypothesis driven research grant applications, and public-private partnerships. The Wistar Molecular Screening Facility was developed with support from the Lankenau Institute for Medical Research, the Commonwealth of Pennsylvania Department of Community and Economic Development Keystone Innovation Zone initiative, The F. M. Kirby Foundation, The CLAWS Foundation, The Florence & Daniel Green Foundation, The McClean Contributionship, From The Heart Foundation, and the Noreen O?Neill Foundation for Melanoma Research.

Proper citation: Wistar Molecular Screening Facility (RRID:SCR_010208) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/histology-core-facility-iu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 30,2024. The Histology Core of the Department of Anatomy and Cell Biology at the Indiana University School of Medicine provides histological services for basic science (non-clinical) research. Both mineralized (plastic embedded) and soft tissue (paraffin embedded) specimens can be prepared.

Proper citation: Indiana University School of Medicine Histology Core Facility (RRID:SCR_011020) Copy   

•   Source: SciCrunch Registry

http://www.tmslab.org/tmscore.php

At the Berenson-Allen Center for Noninvasive Brain Stimulation (CNBS) at Beth Israel Deaconess Medical Center and Harvard Medical School we have three distinct missions: Research, Education and Patient Care. Our research explores brain-behavior relations, brain plasticity and its modulation, employing different noninvasive brain stimulation techniques combined with careful task design, electroencephalography, and functional brain imaging. Educational efforts feature several Continuing Medical Education Courses including a week long intensive course in noninvasive brain stimulation offered 3 times per year. Our clinical program offers noninvasive brain stimulation for treatment of neuropsychiatric disorders such as depression and schizophrenia, epilepsy, and chronic pain. Clinical work also includes studies of central motor conduction time, cortical excitability, and noninvasive cortical mapping.

Proper citation: BIDMC Transcranial Magnetic Stimulation Core (RRID:SCR_011022) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/center-for-nanotechnology-and-molecular-materials-wfu

The Center for Nanotechnology and Molecular Materials at Wake Forest University was founded in 2004 and serves scientists and engineers from both public and private interests in the Piedmont Triad and surrounding communities.

Proper citation: WFU Center for Nanotechnology and Molecular Materials (RRID:SCR_011023) Copy   

•   Source: SciCrunch Registry

http://eagle-i.itmat.upenn.edu/i/0000013f-8bde-1d59-a468-831a80000000

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on May 22,2024.Core facility that provides the following services: Recombinant plasmid DNA engineering, Recombinant protein production via Baculovirus expression systems (BVES), Recombinant protein production in prokaryotic systems, Recombinant protein purification, Retrovirus production service. The Protein Expression Facility is a shared resource laboratory that provides Wistar Cancer Center Members and non-Wistar scientists technical assistance with viral vector preparation and the expression and purification of recombinant proteins. The Facility has greater than 20 years of experience in recombinant protein expression with special expertise in the use of baculovirus expression systems (BVES). The Facility offers the following services: 1. Recombinant plasmid DNA engineering 2. Viral vector production (i.e. baculovirus and retrovirus) 3. Analytical and preparative scale expression of nascent or epitope-tagged recombinant proteins 4. Protein purification These goals are accomplished by a centralized laboratory with dedicated, experienced staff, which enables high-throughput, economy of scale, virus preparation and protein expression services, including quality assurance and control procedures to ensure efficient, consistent production and purification of recombinant proteins and viral vectors. Many recombinant proteins produced by the facility have been used for crystallization efforts, analytical biochemistry studies designed to investigate enzymatic properties, structure-function relationships between protein-protein, protein-nucleic-acid, and protein-small molecule interactions, custom antibody production, experimental cancer vaccines, and development of miniaturized assays for small molecule screening. The facility is supported in part by an NCI Cancer Center Support Grant and a grant from the NIH National Institute of Aging (PO1 AG031862).

Proper citation: Wistar Protein Expression Facility (RRID:SCR_010210) Copy   

•   Source: SciCrunch Registry

https://www.wistar.org/resources/proteomics-metabolomics-facility/

Core facility that provides the following services: In-gel protease digestion service, LC-MS/MS protein identification service, Gel/LC-MS/MS Comprehensive analysis of a subproteome or proteome, MudPIT (LC/LC-MS/MS) analyis?comprehensive analysis of a subproteome or proteome, Reverse phase microbore HPLC peptide mapping service, MALDI mass spectrometry, ESI of intact proteins, Post-translational modification identifications, Custom proteomics database creation, Custom proteomics data analysis, Proteomics methods development. The Wistar Proteomics Facility provides mass spectrometry (MS) and sequence analysis of proteins and peptides at maximum sensitivity using state-of-the-art instruments and methods. The most commonly used services are identifications of either purified proteins or complex protein mixtures, such as sub-proteomes or complete proteomes, using electrospray ionization tandem mass spectrometry (ESI MS/MS). Typically, either individual bands are excised from 1-D SDS gels, or the entire gel lane is analyzed by slicing it into uniform fractions followed by trypsin digestion and nanocapillary HPLC interfaced directly with hybrid ion trap mass spectrometry (Gel/LC-MS/MS). Data is analyzed and filtered to produce low false-positive rates. Several options are available for quantitatively comparing protein changes in related samples, and additional options will be implemented in the future. Complementary services include reverse-phase microbore HPLC peptide mapping with UV detection and mass measurements of intact peptides and proteins using MALDI MS or ESI MS. Posttranslational modification (PTM) analyses including identifications of specific modified residues also are provided, although investigators should recognize that in most cases these studies are quite complex and require substantial effort. These studies, as well as analyses of complex protein mixtures, usually require preparation of custom sequence databases and/or custom data analyses, which can be provided by the facility as needed.

Proper citation: Wistar Proteomics and Metabolomics Core Facility (RRID:SCR_010211) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/abby-and-howard-p-milstein-chemistry-core-facility-cornell

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 11,2025. The Milstein Synthetic Chemistry Core Facility was created through the generosity of Weill Cornell Overseer Howard P. Milstein. The facility provides the equipment and expertise to assist investigators in several areas. Utilizing a newly renovated organic synthesis laboratory, we have the capacity to design and execute efficient and economical chemical syntheses. Additionally, assistance in the purification and identification of unknown metabolites can be provided. The facility primarily serves Weill Cornell Medical College, but can occasionally extend its services to include the tri-institutional academic community.

Proper citation: WCMC Abby and Howard P. Milstein Chemistry Core Facility (RRID:SCR_011025) Copy   

•   Source: SciCrunch Registry

http://xula.eagle-i.net/i/00000135-585e-7c1a-77e4-a45080000000

Core facility that provides the following services: Animal husbandry. To provide the best husbandry and environment for housing, maintaining, and caring for research and laboratory animals used at Xavier University, with in all applicable guidelines, and to assist users by providing information and support for handling and care of animals.

Proper citation: XULA Animal Care Facility (RRID:SCR_010214) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/macromolecular-x-ray-crystallography-facility-isu

The Macromolecular X-ray Crystallography Facility at Iowa State University provides a Rigaku/MSC rotating anode generator for single crystal X-ray diffraction studies, training in crystallography techniques, and a computer lab equipped with crystallography software. Facility services are provided on a fee basis and include consultation on protein purification, crystallization, and crystal optimization, as well as assistance with crystal screening, data collection, data processing, and structure determination and analysis. The following outline is used for general planning of a crystallography project: Protein purification: concentrated protein > 95% pure Crystallization: 3D, mountable crystals Crystal screening: search for high quality, high resolution crystals Data collection: using facility or synchrotron equipment Structure determination: processing, phasing, refinement, modeling, analysis, deposition

Proper citation: ISU Macromolecular X-ray Crystallography Facility (RRID:SCR_011028) Copy   

•   Source: SciCrunch Registry

http://xula.eagle-i.net/i/00000134-f6b4-e33e-77e4-a45080000000

Core facility that provides the following services: Bioassays service, Functional studies service, Gene expression service, Molecular biology service, Mass spectrometry based global scale protein profiling, 2D Gel Electrophoresis, Data analysis services. The RCMI Cell and Molecular Biology Core (CMB Core) provides focused services using cell and molecular biological techniques. It also provides access, upkeep and training on ?state of the art? equipment. Funding by the RMCI allows these services to be offered at minimal cost to users of the core. Technical services and necessary consumable supplies are provided to support cancer research projects at Xavier University. The long term goal of the Cell and Molecular Biology Core is to enhance the overall biomedical research capabilities at Xavier University.

Proper citation: XULA RCMI Cell and Molecular Biology Core (RRID:SCR_010218) Copy   

•   Source: SciCrunch Registry

https://isotope.uark.edu/equipment/

Facility provides high quality stable isotope analysis. Equipment includes Picarro G2201-I Cavity ring-down spectrometer for concentration and carbon isotope measurements of CH4 and CO2 gases, EA IsoLink CN analyzer and Delta V Plus Isotope Ratio Mass spectrometer for Carbon, Nitrogen and Sulphur analysis of solids, Delta V Advantage Isotope Ratio Mass with dual Gas Bench II peripherals, Delta V Advantage Isotope Ratio Mass with dual Gas Bench II peripherals, Shimadzu 2010 Quadrapole GC/MS with FID and liquid and headspace autosampler, Delta V Plus IRMS with TCEA and GC-IsoLink and Triplus RSH autosampler,

Proper citation: University of Arkansas Stable Isotope Lab Core Facility (RRID:SCR_011032) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/chemical-gmp-synthesis-facility

The Chemical GMP Synthesis Facility is a state-of-the-art manufacturing facility for small and large molecule therapeutics for clinical trials. The CGSF provides services for drug discovery, process research, development and early clinical manufacturing of pharmaceutical drug substances (APIs) that meet FDA requirements. www.cityofhope.org/chemicalgmp

Proper citation: Beckman Research Institute Chemical GMP Synthesis Facility (RRID:SCR_012174) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/analytical-instrumentation-facility-ncsu

The NCSU Analytical Instrumentation Facility (AIF) is a North Carolina State University resource for materials characterization. AIF operates a number of major analytical instruments providing quality analyses for all who require it. These instruments are operated and maintained by a professional staff who are experienced in the design and implementation of materials characterization experiments. For those who desire hands on involvement in their analyses, AIF staff trains users to operate analytical instrumentation, design efficient analytical experiments, and properly interpret the resulting data. In addition, AIF staff is involved in the development and/or enhancement of analytical techniques in a continuing effort to provide the level of capabilities required by the ever evolving needs of the NCSU research community. AIF provides short courses as well as formal classroom instruction to insure that NCSU''''s future engineers and scientists can, upon graduation, take with them an understanding of modern analytical techniques and an understanding of the instrumentation required to implement them.

Proper citation: NCSU Analytical Instrumentation Facility (RRID:SCR_012173) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/proteomics-core-iu

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 25,2024. Indiana University School of Medicine Proteomics Core Facility provides protein and proteomic analysis services for protein identification, characterization, and quantification. The Core encourages collaborations that apply the tools of proteomics to cutting-edge biomedical research. Established in 2001, the Core has become a center not only for services but also for collaborative research and development of new technological platforms for proteomic research. The Core is available to Indiana Universities and the wider research community. Over the years, our facility has worked with many pharmaceutical and biotech companies, and developed a number of SOPs for biomarker discovery, mass spec-based protein assays, and biomarker candidate validation. Our major platforms are label-free protein quantification for biomarker discovery and multiple-reaction-monitoring (MRM) for protein assays and biomarker validation. Our goal is to deliver value to our investigators and our community as a world-class proteomics core lab providing services to meet the critical needs of biomedical researchers in life science industries and academia.

Proper citation: Indiana University School of Medicine Proteomics Core (RRID:SCR_011000) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/automatic-weather-station

The Automatic Weather Station is located within the sports grounds of Macquarie University at North Ryde, Sydney, Australia. Its latitude, longitude and elevation are 33 degrees 45 minutes and 55.1 seconds South and 151 degrees 7 minutes and 3.2 seconds East and 66.8 m above mean sea level (accurate to 4.4 m). Access to both real-time and archived data is available and information is provided on what is measured and the instrumentation used. The data recorded at our weather station are archived at 1 minute intervals over the last 7 days, and at 15 minute intervals going back to April 1992.

Proper citation: Macquarie University Automatic Weather Station (RRID:SCR_011080) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/scipac

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on October 30,2023. Our contract antibody service is designed to be highly flexible to ensure we meet the individual needs of our customers. Whether you are looking for a complete start to finish service or simply one aspect such as clone yield optimisation, then SCIPAC can meet your needs. Our service caters for both monoclonal antibodies as well as recombinant antibodies.

Proper citation: SCIPAC (RRID:SCR_012172) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/biomolecular-frontiers-research-centre

The Biomolecular Frontiers Research Centre brings together national and international researchers in the molecular and cellular analysis of living systems.

Proper citation: Macquarie University Biomolecular Frontiers Research Centre (RRID:SCR_011006) Copy   

•   Source: SciCrunch Registry

http://eagle-i.ea.vanderbilt.edu/i/00000138-7be3-69fb-480b-864680000000

Vanderbilt Transgenic Mouse/Embryonic Stem Cell Shared Resource (TMESCSR) provides services that facilitate the generation, storage and regeneration of genetically altered mice.

Proper citation: Vanderbilt Transgenic Mouse/Embryonic Stem Cell Shared Resource (RRID:SCR_010200) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/animal-behaviour-laboratory

Exploring the mechanisms responsible for behaviour of clear functional importance.

Proper citation: MQ Animal Behaviour Laboratory (RRID:SCR_011067) Copy   

•   Source: SciCrunch Registry

http://www.scienceexchange.com/facilities/macquarie-university-centre-for-analytical-biotechnology-mucab

The Centre manages substantial instrumentation resources appropriate for the contemporary study of biomolecules and natural products.

Proper citation: Macquarie University Centre for Analytical Biotechnology (RRID:SCR_011060) Copy   

•   Source: SciCrunch Registry