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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.chumontreal.qc.ca/en/crchum/core-facilities-and-services/phenotyping-rodents-metabolic
Core facility offers services unique in Canada for study of carbohydrate and energy metabolism in rodents such as routine tolerance tests of glucose, lipids, pyruvate, insulin and metabolic cages.Provides expertise in performing hyperglycemic clamps as well as Hyperinsulinemic-euglycemic clamps. Offers services for research projects carried out at the cellular or tissue level and on animals,complete metabolic phenotyping of genetically modified rodents, evaluation of effect of pharmacological or molecular interventions on carbohydrate and/or energy metabolism in healthy rodent models or in obese or diabetic models.All surgical procedures, metabolic tests, dosing and data analyses are carried out by our staff.
Proper citation: University of Montreal Health Centre Rodent Metabolic Phenotyping Core Facility (RRID:SCR_023574) Copy
https://uclouvain.be/en/research-institutes/irec/cytoflux
Offers tissues dissociation and single cell preparation, analysis and cell sorting under supervision of research logistician.Provides instruments BD FACSCantoII for analysis and BD FACSAriaIII for cell separation and services including Samples preparations and multiparametric panels consultancy, Acquisition and analysis of multiparametric samples, Cell Sorting, Data Analysis.
Proper citation: Catholic University of Louvain Institute of Experimental and Clinical Research Flow Cytomerty Platform Core Facility (RRID:SCR_023664) Copy
Imaging facility of Life Sciences Institute with state-of-the-art fluorescence microscopy equipment. Applications include FLIM, FRET, FRAP, TIRF and high throughput content screening (small molecule and siRNA). Provides access, user training, and technical assistance for super resolution microscopy, confocal microscopy (point laser scanning or spinning disk), high throughput imaging and image deconvolution, 3D reconstruction, and quantitative analysis.
Proper citation: University of British Columbia LSI Imaging Core Facility (RRID:SCR_023783) Copy
BioPolymers, Automated Cellular Infrastructure, Flow, and Integrated Chemistry Materials Innovation Platform is platform dedicated to scalable production of bio-derived building blocks and polymers from yeast, fungi, and bacteria. Automated high-throughput synthesis and characterization of bio-derived polymers aims to accelerate discovery and speed development of new high-performance materials.
Proper citation: University of California BioPACIFIC MIP Core Facility (RRID:SCR_023540) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/genomics/index.html
Provides Next Generation DNA and Sanger sequencing services; single cell genomics assays by 10x Genomics, and Nanostring technology targeted gene expression assays.
Proper citation: University of Nebraska Medical Center UNMC Genomics Core Facility (RRID:SCR_023539) Copy
https://www.vumc.org/diet-body-metabolism-core/welcome
Core provides valid, reliable, appropriate and cost effective methods to investigators that facilitate all types of human research (T1, T2 and T3) and study designs. These methods include 24 hour diet recalls, diet histories, food records/diaries, food frequency questionnaires, observed intakes and weighed intakes of all forms of dietary and nutrient intake (foods, beverages, dietary supplements, liquid nutrition supplements, enteral tube feedings, parenteral support and medications).
Proper citation: Vanderbilt University Medical Center Vanderbilt Diet, Body Composition, and Human Metabolism Core Facility (RRID:SCR_023538) Copy
https://www.cores.emory.edu/iemc/
Core helps investigators use the latest technologies on structural research in their projects. Provides expertise in experimental needs.
Proper citation: Emory University Robert P. Apkarian Integrated Electron Microscopy Core Facility (RRID:SCR_023537) Copy
https://www.bcchr.ca/gut4health
Facilitates microbiome studies for researchers at British Columbia Children Hospital Research Institute and University of British Columbia. Core offers processing and storing biological specimens, and sequencing and analysis of microbial communities for various research studies, including basic science, clinical, translational, and epidemiological projects.
Proper citation: University of British Columbia Gut4Health Microbiome Core Facility (RRID:SCR_023673) Copy
http://www.med.uvm.edu/mricenter/home
Core to perform functional brain imaging studies collaboratively with Department of Radiology utilizing Tesla Phillips Achieva scanner and CNRU experimental image capture and analysis system. Works collaboratively with other laboratories within Psychiatry Department to serve mutual research interests. Collaborates across Neuroscience Consortium with investigators in Departments of Neurology, Anatomy, Psychology, as well as GCRC investigators to further develop brain imaging expertise at UVM. Functional imaging experimental and analysis expertise reside in CNRU-Psychiatry. Technical personnel necessary to operate imaging program including MR physicist, fMRI radiologist, and technicians are employed by Department of Radiology in College of Medicine.
Proper citation: University of Vermont Functional Brain Imaging Core Facility (RRID:SCR_023546) Copy
https://rnainnovation.med.upenn.edu/scientific-groups/mrna-core/
Core focuses on exploring mRNA technology and lipid nanoparticles for various applications including tissue and cell targeting. Offers Optimization and production of in vitro transcribed mRNA, Small scale production of sequence optimized in vitro transcribed mRNA, Incorporation of modified nucleosides to modulate activity, Off the shelf in vitro transcribed mRNA encoding reporter genes or cancer antigens,Labelled mRNA for nanoparticle tracking and microscopy, Encapsulation into commercially available proprietary and non proprietary lipid nanoparticles through LNP core.
Proper citation: University of Pennsylvania Institute for RNA Innovation Engineered mRNA and Targeted Nanomedicine Core Facility (RRID:SCR_023665) Copy
https://www.sdstate.edu/biology-and-microbiology/functional-genomics-core-facility
Core provides access and training on range of instruments in areas of genomics, molecular biology, imaging, and chemical/metabolite analysis to support research on the SDSU campus.
Proper citation: South Dakota State University Functional Genomics Core Facility (RRID:SCR_023786) Copy
https://uclouvain.be/en/technology-platforms/pgen.html
Core provides services including Sequencing (Sanger, NGS); Genotyping (micro array, fragment analysis); Molecular karyotyping (micro array); Bioinformatics (exomes [WES], genomes [WGS], gene panels [panels], transcriptome [RNAseq]). Equipment includes Illumina MiSeq sequencer;Ion Torrent Ion Proton sequencer and an Ion Chef for sample preparation;HPC cluster for bioinformatics processing of NGS data (WES, WGS, panels, RNASeq);Affymetrix microarray platform;Sanger sequencer and fragment analyser;Contracts for outsourcing WES, WGS and RNAseq, according to public procurement regulations;Highlander software, developed in-house, for variant analysis from NGS data.
Proper citation: Catholic University of Louvain Genomics platform Core Facility (RRID:SCR_023707) Copy
https://sqi.northwestern.edu/core-facilities/antec/
Facility houses research equipment for evaluating materials and biological preparations, and offers 3D printing and 3D scientific illustration services. Available instruments include Cytation3 Automated Microscope Plate Reader, BioTek Inc.; Zetasizer Nano ZSP, Malvern Inc.; Lyophilizers FreeZone 6 and 6 Plus, Labconco; Azure300, Chemiluminescent Gel Imager, Azure Biosystems; Real-Time PCR I-cycler CFX-Connect, Bio-Rad Laboratories; Centrifuge Sorvall X1R, ThermoFisher; MCR302 Rheometer, Anton Paar Inc.; Plasma Cleaner, Harrick Plasma; NanoSight300, Malvern Instruments (Evanston); IncuCyte Live Cell Analysis System, Sartorius; Piuma Nanoindenter, Optics 11; Freezer/Mill, SPEX Sample Prep; J-1500 Circular Dichroism Spectrometer, JASCO.
Proper citation: Northwestern University Analytical BioNanoTechnology Equipment Core Facility (RRID:SCR_023706) Copy
https://www.bif.northwestern.edu/
Shared use and training facility. Servies include Confocal Laser Scanning Microscopy, DIC (Differential Interference Contrast Microscopy), FCS (Fluorescence Correlation Spectroscopy), FLIP (Fluorescence-Loss-In-Photobleaching), FRAP (Fluorescence Recovery After Photobleaching),FRET (Fluorescence/ Forster Resonance Energy Transfer),Live-cell Imaging,Phase Contrast Microscopy,Widefield Fluorescence Microscopy,Image Processing and Analysis. Services include poster printing, and specimen preparation. Provides training for most instruments. Instruments include Leica DM6B Fluorescent Microscope (Hogan 5-112), Leica TCS SP8 Confocal Microscope (Hogan 5-128),Leica SP5 II Confocal Microscope (Hogan 5-114),Leica Spinning Disk Confocal Microscope (Hogan 5-113),DeltaVision Deconvolution Microscope (Hogan 5-111),Olympus IX83 Inverted Fluorescent Microscope (Silverman Hall 1-567),Olympus IX53 Inverted Color Microscope (Silverman Hall 1-567), LionHeart Automated Microscope BioTeck (Hogan 5-110).
Proper citation: Northwestern University Biological Imaging Core Facility (RRID:SCR_017767) Copy
Central micro/nano fabrication facility of Northwestern University. Provides range of nanofabrication equipment and technical expertise. Supports research in all areas of science, engineering, medicine, and interdisciplinary fields.
Proper citation: Northwestern University Micro/Nano Fabrication Core Facility (RRID:SCR_017779) Copy
https://sites.northwestern.edu/nucapt/
Facility specializes in high resolution chemical imaging by three dimensional atom probe tomography. APT produces three-dimensional (3D) atom-by-atom elementally and isotopically resolved image with sub-nanometer spatial resolution of sample volume typically 100 x 100 x 300 nm^3, by simultaneous high resolution direct-space imaging and atom-by-atom time of flight mass spectrometry. APT is particularly suited to study nano- or nanostructured materials.
Proper citation: Northwestern University Center for Atom Probe Tomography Core Facility (RRID:SCR_017770) Copy
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