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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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On page 44 showing 861 ~ 880 out of 2,024 results
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https://www.mskcc.org/research/ski/core-facilities/mouse-genetics

Core facilitates the use of mouse molecular genetics at MSK for in vivo studies of gene functions germane to cancer. Provides expertise in generation and effective use of genetically engineered mouse (GEM) models—namely, molecular and cell biology, embryo micromanipulation, and reproductive biology. Molecular and cellular biology services cover design and assembly of genome engineering reagents, such as donor transgenes and CRISPR/Cas9; performing all aspects of gene targeting in mouse embryonic stem (ES) cells; identification and verification of alleles carried by a generated GEM model; and establishment of new ES cells from a variety of GEM lines. Provides consultation and training for the design and production of GEM models, ES cell culture and manipulation, and mouse reproduction and genetic crosses.

Proper citation: Memorial Sloan Kettering Cancer Center Mouse Genetics Core Facility (RRID:SCR_027803) Copy   


https://www.mskcc.org/research/ski/core-facilities/pro-cel

Core supports MSK investigators who wish to capture self-reported information from culturally diverse patients, caregivers, clinical staff, and community members. The faculty of the PRO-CEL Core are nationally recognized social and behavioral scientists and community engagement experts who provide technical assistance to all users throughout multiple stages of research, including grant and protocol development, research study assistant and support staff training, and result dissemination. Provides methodological support for clinical trial, behavioral, and population-based research that seeks to engage community or minority populations.

Proper citation: Memorial Sloan Kettering Cancer Center Patient- Reported Outcomes, Community Engagement, and Language Core Core Facility (RRID:SCR_027805) Copy   


https://www.vai.org/research/core-services/spatial-collaborative-services/

Spatial Collaborative Services combines expertise and technology from VAIs Genomics Core and Optical Imaging Core to offer investigators a seamless pipeline for spatial imaging. Services include consultation, histology preparation, sequencing and imaging based spatial platforms.

Proper citation: Van Andel Institute Spatial Collaborative Services Core Facility (RRID:SCR_027861) Copy   


https://www.augusta.edu/research/core/medical-sculpture.php

Department of Medical Illustration’s Medical Sculpture Core advances education and research capabilities in medical sculpture. The space serves as an AU Core Research Lab to provide expertise in medical sculpture, volumetric visualization, and 3D printing. This lab space will offer educational and research opportunities for students to develop medical models such as surgical simulation models and patient education models. The research will improve surgical and medical training and provide insight into materials and technology to improve patient care.

Proper citation: Augusta University Medical Sculpture Core Facility (RRID:SCR_027863) Copy   


https://mic.massgeneralbrigham.org

Core facility that provides microscopy training, imaging solutions, image processing and analysis services, and consultation. Offers imaging techniques and expertise, including spinning disc confocal microscopy, two-photon confocal microscopy, super resolution microscopy, total internal reflection microscopy, wide field microscopy, fluorescence spectroscopy, photo-manipulation techniques (e.g. FRAP, photoablation, optogenetics, and optical tweezers) and live cell imaging.

Proper citation: Massachusetts General Hospital Brigham Center of Excellence for Molecular Imaging Core Facility (RRID:SCR_027865) Copy   


https://mcity.umich.edu/

Core for building and testing mobility innovation is part of the University of Michigan Transportation Research Institute. Helps advance safe and efficient transportation and mobility solutions. Makerspace for mobility and transportation innovators. Offers open-source tools, remote or on-site testing.

Proper citation: University of Michigan MCity Core Facility (RRID:SCR_027857) Copy   


http://www.mtu.edu/mcff

Core facility provides tools for imaging, analysis, environmental testing, and micro/nanofabrication. Offers data, expertise, and hands-on training. From advanced materials to environmental systems, MCFF is the hub where discovery meets precision.

Proper citation: Michigan Technological University Materials Characterization and Fabrication Core Facility (RRID:SCR_027872) Copy   


https://cryo-em.charite.de/en/

Facility for high resolution imaging of biological samples at cryogenic temperatures. Amongst other applications such as single particle data collection, our high-end instrumentation is suited to perform in situ structural biology by combining cryoCLEM, lamella FIB-milling, and cryo-electron tomography.

Proper citation: Charité Berlin University of Medicine Cryo-Electron Microscopy Core Facility (RRID:SCR_027961) Copy   


https://experimentelle-medizin.charite.de/en/transgenic_technologies

Core provides services supporting generation, modification, cryopreservation, and rederivation of genetically modified rodent models for biomedical research, generates genetically modified mouse models via both targeted and random mutagenesis using tools such as CRISPR/Cas9 in zygotes or embryonic stem (ES) cells, provides cryopreservation and rederivation of existing animal models to preserve hygienic integrity. Services for rodent transgenic model development include: Pronuclear Injection and amp; Viral Transgenesis with introduction of genetic constructs into zygotes using microinjection or lentiviral systems; ES Cell-Based Techniques: use of embryonic stem cell manipulation for genetic targeting; Embryo Transfer: transferring manipulated embryos into recipient females; In Vitro Fertilization (IVF): assisted reproductive technology to generate embryos for manipulation or cryopreservation; Cryopreservation: freezing of embryos and sperm for archiving or rederivation of lines as required. Facility’s expertise includes quality control of cryopreserved material to ensure viability upon thawing.

Proper citation: Charité Berlin University of Medicine Transgenic Technologies Core Facility (RRID:SCR_027960) Copy   


http://vcf.charite.de/en

Core provides comprehensive services for generation of viral particles from existing vectors or newly created vectors.

Proper citation: Charité Berlin University of Medicine Viral Core Facility (RRID:SCR_027965) Copy   


https://www.mayo.edu/research/core-resources/precision-mouse-engineering-core/overview

Core generates transgenic and gene-targeted mice for researchers at Mayo Clinic's campuses in Arizona, Florida and Minnesota to enable researchers to observe how genes, or mutant variations of genes, are expressed. Provides services to all Mayo Clinic faculty and staff engaged in research. Also, services are offered to non-Mayo investigators and research collaborators.

Proper citation: Mayo Clinic Precision Mouse Engineering Core Facility (RRID:SCR_027967) Copy   


https://www.mayo.edu/research/core-resources/biomedical-imaging-resource-core/overview

Mayo Clinic's Biomedical Imaging Resource Core in Rochester, Minnesota, focuses on supporting and advancing research in biomedical imaging and visualization sciences. Provides guidance on protocol design, routine image analysis, and custom software and hardware solutions. Also, media and model production resources are available to investigators for the creation of high-quality visualizations and physical models of research data.Core provides services to all Mayo Clinic faculty and staff engaged in research. Also, services may be available on a limited basis to investigators and research collaborators outside Mayo Clinic. Before scheduling, contact the core to design optimal settings for the specified imaging task.

Proper citation: Mayo Clinic Biomedical Imaging Resource Core Facility (RRID:SCR_027968) Copy   


https://www.lsuhs.edu/centers/center-for-post-transcriptional-regulation/research-cores

Core enables generation of genetically defined human iPSC-derived hepatocytes, CRISPR/Cas9 mediated gene editing, and primary mouse hepatocyte isolation.

Proper citation: Louisiana State University Health Sciences Center Shreveport hiPSC and Cell Models Core Facility (RRID:SCR_027946) Copy   


https://health.ucdavis.edu/cancer/research/sharedresources/mouse

Mouse Biology Shared Resource (MBSR) provides knockout, transgenic, and humanized murine cancer models and related services for advancing translational cancer research. Additionally, the MBSR offers services to enhance the use of existing mouse models or to facilitate the development of new mouse models for cancer research, including genetic alteration (e.g., CRISPR/Cas9-mediated gene targeting, transgenesis), surgical manipulation (e.g., patient-derived xenografts (PDX), cell-derived allografts (CDA) and xenografts (CDX)), and environmental challenges (e.g., diet, chemotherapeutic agents). can produce a wide range of allele-speci?c mouse models and offers innovative technologies to phenotype mouse models that mimic human conditions.

Proper citation: UC Davis Health Comprehensive Cancer Center Mouse Biology Shared Resource MBSR Core Facility (RRID:SCR_027912) Copy   


https://cancer.mcw.edu/researchers-and-clinicians/shared-resources/structural-biology-shared-resource-sbsr

SBSR core consists of the Protein Purification unit and the Structure Determination unit. Protein Purification unit produces homogeneous, high-quality proteins well suited for downstream biophysical studies and structure determination. Structure Determination unit employs X-ray crystallography, Cryo-EM, and advanced AI-assisted analytical tools for structure determination and imaging.

Proper citation: Medical College of Wisconsin Cancer Center Structural Biology Shared Resource Core Facility (RRID:SCR_027924) Copy   


https://www.broadinstitute.org/genomics

Facility that generates, analyzes, and interprets high-throughput genomic data to understand the genetic basis of disease. Genomics Platform has played leadership role in the design, data generation, and methods development in support of major genomic resource projects.Through the Broad Clinical Labs (BCL), formerly known as the Clinical Research Sequencing Platform (CRSP), it supports clinical trials, diagnostic testing, and major initiatives, including COVID-19 testing. Offers services including Nucleic Acid Extractions, Single Cell Sequencing (using 10x Genomics products), and GWAS Arrays.

Proper citation: Broad Institute Genomics Platform (RRID:SCR_027987) Copy   


https://www.pm-tumorimmunotherapyprogram.ca/centre-for-integrative-immune-analysis

Core provides specialized, high-dimensional immune profiling for clinical and translational studies. It enables researchers to analyze immune responses using advanced flow cytometry, CyTOF, genomics, and cytokine analysis, helping to improve cancer treatments and patient outcomes.

Proper citation: University Health Network Princess Margaret Cancer Centre Integrative Immune Analysis Core Facility (RRID:SCR_028046) Copy   


https://icv.institutducerveau.org/

Core facility provides infrastructure and services to academic researchers, biotech companies and industry partners that need vectors or cell culture models for their studies. Focuses on generating cell models, genetic modification, viral vector development, and advanced flow cytometry analysis.

Proper citation: Paris Brain Institute Cellular Engineering, Cell Culture and Cytometry Core Facility (RRID:SCR_028048) Copy   


https://ambio.charite.de/en/

Core for advanced fluorescence bioimaging. Provides both the infrastructure and expertise necessary for researchers with diverse backgrounds to efficiently perform advanced fluorescence microscopy imaging projects on the molecular, cellular and tissue level. AMBIO services include individual user training and assistance, and if necessary supervised image acquisition and guidance for data analysis.

Proper citation: Charité Berlin University of Medicine Advanced Medical Bioimaging Core Facility (RRID:SCR_027989) Copy   


https://acewm-aau.org/about-us

Provides technical, on-the-job training to build expertise in water management. Provides research, and training in water science, policy, and management to foster sustainable, community-driven water solutions across Eastern and Southern Africa.

Proper citation: Addis Ababa University Africa Center of Excellence for Water Management Core Facility (RRID:SCR_028132) Copy   



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