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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Web application as free reference manager and academic social network to organize your research, collaborate with others online, and discover the latest research. Automatically generate bibliographies, Collaborate easily with other researchers online, Easily import papers from other research software, Find relevant papers based on what you're reading, Access your papers from anywhere online, Read papers on the go with the iPhone app. The software, Mendeley Desktop, offers: * Automatic extraction of document details * Efficient management of your papers * Sharing and synchronization of your library (or parts of it) * Additional features: A plug-in for citing your articles in Microsoft Word, OCR (image-to-text conversion, so you can full-text search all your scanned PDFs), etc The website, Mendeley Web, complements Mendeley Desktop by offering these features: * An online back up of your library * Statistics of all things interesting * A research network that allows you to keep track of your colleagues' publications, conference participations, awards etc * A recommendation engine for papers that might interest you.
Proper citation: Mendeley (RRID:SCR_002750) Copy
Genes to Cognition (G2C) Online is about modern neuroscience. It focuses on cognitive disorders, cognitive processes, and research approaches. Use the dynamic network maps to explore our library of 750+ unique items. Or, use the linear Selected Items menu on top of each map to tour selected content. Read the G2C blog, use simple mapper, or the 3-D brain, an interactive model of the brain. Disorders included in this site: ADHD, Alzheimer's Disease, Autism, Bipolar Disorder, Depression, Schizophrenia Cognitive Processes include: Attention, Language, Learning and Memory, Perception, and Thinking Research Approaches include: Bioinformatics, Ethics, Gene Finding, Model systems, Neuroimaging, Psychology. Navigation: Interact with the dynamic Networks Maps to explore the full catalog of content. Roll-over a node on the map for a preview and click to open the content. Move on to other content by returning to the network map. Each node you visit on the map gets flagged. Follow the Selected Items Subway Line for an overview of a topic. Roll-over a subway node for a preview and click to open the content. Other Features: Most content items include links to Related Items, which allow you to explore further. The Glossary includes over 300 neuroscience keywords. Search for content using keywords or id number. Select a preferred network map to view the content in context. Open/close the History at the lower left to view visited content. Your history is stored until you clear it. Simple Mapper - We developed Simple Mapper to power this web site on the brain. Now, you can use it to organize what comes out of yours! With Simple Mapper create and save concept maps, network diagrams, or flowcharts for personal use or to share with others. 3-D Brain - The G2C Brain is an interactive 3-D model of the brain, with 29 structures that can be rotated in three-dimensional space. Each structure has information on brain disorders, brain damage, case studies, and links to modern neuroscience research. Ideal for students, researchers, and educators in psychology and biology. Also available for download: 3D Brain App for iPhone and iPod Touch!
Proper citation: Genes to Cognition Online (RRID:SCR_002746) Copy
https://github.com/UCSFBiomagneticImagingLab/nutmeg
Software MEG/EEG analysis toolbox for reconstructing neural activation and overlaying it onto structural MR images. Toolbox runs under MATLAB in conjunction with SPM2 and can be used with Linux/UNIX, Mac OS X, and Windows platforms.
Proper citation: NUTMEG (RRID:SCR_002748) Copy
http://www.ualberta.ca/~aprochaz/Index.html
The lab of Arthur Prochazka, whose research focuses on routing electrical current from surface electrodes to deep-lying nerves using implanted conductors. His research mostly focuses on muscle physiology. Current fields of research: * Stimulus Router System: A new family of implanted neuroprostheses. It comprises an implanted lead that picks up some of the current delivered through the skin by a surface stimulator and delivers it to a target nerve via a nerve cuff. The SRS has the advantages of an implanted stimulator: selectivity, reproducibility and convenience, at a fraction of the cost * Bionic Glove: Hand opening and closing stimulator for C5-C6 tetraplegic people. It is based on Functional Electrical Stimulation (FES). * In-home Telerehabilitation: Providing exercise sessions over the internet. * Interactive Receptor Model: An online model explaining muscle spindles and tendon organs. * Spinal Motoneuron Activity During Gait * Robocats: Mathematical models for locomotion. * Rigidity Analyzer: A better means of assessing rigidity. * General Research: Fundamental questions in our field of neurophysiology. * Spinal Cord Microstimulation: Restoring bladder function after spinal cord injury.
Proper citation: Arthur Prochazka Laboratory, University of Alberta (RRID:SCR_002747) Copy
https://code.google.com/p/methylkit/
An R package for DNA methylation analysis and annotation from high-throughput bisulfite sequencing., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: methylKit (RRID:SCR_005177) Copy
http://www.well.ox.ac.uk/~kgaulton/chaos.shtml
A Perl-based system for annotation of variants identified in high-throughput sequencing experiments. Functionality includes annotation of variants with information relating to population genetics, known transcripts, positional records, and sequence motif-based prediction. In addition, annotated variants can be summarized and extracted to facilitate downstream analysis. There is also basic support for gene-based biological annotation, and eventually will include tools for variant and genotype analysis and visualization.
Proper citation: CHAoS (RRID:SCR_005174) Copy
http://anntools.sourceforge.net/
Software tool for annotating single nucleotide substitutions (SNP/SNV), small insertions/deletions (indels), and copy number variations (CNV) calls generated from sequencing and microarray data. Only human genome build 37/hg19 can be annotated at this time.
Proper citation: AnnTools (RRID:SCR_005170) Copy
http://www.uni-konstanz.de/en/welcome/
University in the city of Konstanz in Baden-Württemberg, Germany. Its main campus was opened on the Gießberg in 1972 after being founded in 1966.
Proper citation: University of Konstanz; Baden-Wurttemberg; Germany (RRID:SCR_005171) Copy
http://www.broadinstitute.org/software/pathseq/
A computational tool for the identification and analysis of microbial sequences in high-throughput human sequencing data that is designed to work with large numbers of sequencing reads in a scalable manner. This process is composed of a subtractive phase in which input reads are subtracted by alignment to human reference sequences, and an analytic phase in which the remaining reads are aligned to microbial reference sequences (viral, fungal, bacterial, archaeal) and de novo assembled. PathSeq is currently available in a cloud computing environment via Amazon Web Services The typical approach one would take to pathogen discovery with PathSeq: RNA or DNA is extracted from the tissue of interest and sequencing libraries are constructed to be run on the next-generation DNA sequencing platform of choice. The resulting sequence data is run through the PathSeq pipeline in a cloud computing environment. PathSeq reports potential microbes in the sequence data as well as the complete set of reads that could not be identified as human or microbial sequences.
Proper citation: PathSeq (RRID:SCR_005203) Copy
http://cbrc.kaust.edu.sa/readscan/
A highly scalable parallel software program to identify non-host sequences (of potential pathogen origin) and estimate their genome relative abundance in high-throughput sequence datasets.
Proper citation: READSCAN (RRID:SCR_005204) Copy
http://odin.mdacc.tmc.edu/~xsu1/VirusSeq.html
An algorithmic software tool for detecting known viruses and their integration sites using next-generation sequencing of human cancer tissue. VirusSeq takes FASTQ files (paired-end reads) as input.
Proper citation: VirusSeq (RRID:SCR_005206) Copy
http://smithlab.usc.edu/methpipe/
A computational pipeline for analyzing bisulfite sequencing data.
Proper citation: MethPipe (RRID:SCR_005168) Copy
In the belief that innovation and discovery occur in direct proportion to quality of training, the Life Sciences Research Foundation administers an international program of postdoctoral fellowships in all areas of the life sciences. Since it was established, in 1981, the Foundation has attracted support from a wide variety of sponsors. The mission of the Life Sciences Research Foundation (LSRF) is to establish partnerships between those who support research in the life sciences and academic institutions for their mutual benefit. The simple vehicle for achieving this partnership is a highly competitive postdoctoral fellowship program. Fellowship Eligibility. Three-year fellowships will be awarded on a competitive basis to graduates of medical and graduate schools in the biological sciences holding M.D., Ph.D., D.V.M. or D.D.S. degrees. Awards will be based solely on the quality of the individual applicant''s previous accomplishments, and on the merit of the proposal for postdoctoral research. Persons doing a second postdoc are eligible only if they are transferring to a different supervisor''s laboratory and embarking on a new project not connected to their previous research. All U.S. citizens are eligible to apply with no geographic restriction on the laboratory of their choice. Foreign applicants will be eligible for study in U.S. laboratories. LSRF fellows must carry out their research at nonprofit institutions. LSRF fellows may change projects, laboratories, and/or institutions during the fellowship as long as the eligibility rules listed here are not violated. A person holding a faculty appointment is not eligible to apply for an LSRF fellowship. The LSRF solicits monies from industry, foundations and individuals to support postdoctoral fellowships in the life sciences. Active solicitation of funds continues, for which we need the assistance of all concerned individuals. We recognize that discoveries and the application of innovations in biology for the public''s good will depend upon the training and support of the highest quality young scientists in the very best research environments. LSRF awards fellowships across the spectrum of the life sciences: biochemistry; cell, developmental, molecular, plant, structural, organismic population and evolutionary biology; endocrinology; immunology; microbiology; neurobiology; physiology; virology. Note: There may be no more than one LSRF fellow in any one laboratory at a time.
Proper citation: Life Sciences Research Foundation (RRID:SCR_005115) Copy
http://archive.gersteinlab.org/proj/rnaseq/IQSeq/
Software for integrated Isoform Quanti?cation Analysis based on A Partial Sampling Framework.
Proper citation: IQSeq (RRID:SCR_005238) Copy
http://cran.r-project.org/web/packages/expands/
Software that characterizes coexisting subpopulations (SPs) in a tumor using copy number and allele frequencies derived from exome- or whole genome sequencing input data. The model amplifies the statistical power to detect coexisting genotypes, by fully exploiting run-specific tradeoffs between depth of coverage and breadth of coverage. ExPANdS predicts the number of clonal expansions, the size of the resulting SPs in the tumor bulk, the mutations specific to each SP and tumor purity. The main function runExPANdS provides the complete functionality needed to predict coexisting SPs from single nucleotide variations (SNVs) and associated copy numbers. The robustness of the subpopulation predictions by ExPANdS increases with the number of mutations provided. It is recommended that at least 200 mutations are used as an input to obtain stable results.
Proper citation: ExPANdS (RRID:SCR_005199) Copy
http://compbio.cs.toronto.edu/ireckon/
An algorithm for the simultaneous isoform reconstruction and abundance estimation. In addition to modelling novel isoforms, multi-mapped reads and read duplicates, this method takes into account the possible presence of unspliced pre-mRNA and intron retention. iReckon only requires a set of transcription start and end sites, but can use known full isoforms to improve sensitivity. Starting from the set of nearly all possible isoforms, iReckon uses a regularized EM algorithm to determine those actually present in the sequenced sample, together with their abundances. iReckon is multi-threaded to increase efficiency in all its time consuming steps.
Proper citation: iReckon (RRID:SCR_005232) Copy
The HFSP supports novel, innovative and interdisciplinary basic research focused on the complex mechanisms of living organisms; topics range from molecular and cellular approaches to systems and cognitive neuroscience. A clear emphasis is placed on novel collaborations that bring biologists together with scientists from fields such as physics, mathematics, chemistry, computer science and engineering to focus on problems at the frontier of the life sciences. The Trust provides funding for research regarding complex biological systems. It offers research grants, post doc fellowships, career development fellowships, and short- long- and cross- disciplinary fellowships. HFSP funding programs are strictly project-related and begin at the postdoctoral level. We have no support for PhD students nor for travel grants to scientific meetings. Nor do we provide sponsorship or funds to organizers of scientific meetings. Research Grants Research Grants are awarded for novel collaborations involving extensive collaboration among teams of scientists working in different countries and in different disciplines. Two types of grants are available: Young Investigators Grants and Program Grants. Postdoctoral Fellowships Postdoctoral Fellowships are available for scientists who wish to work in foreign laboratories, with emphasis on individuals early in their careers who wish to obtain training in a different field of research. Fellows who return to their home countries or move to an HFSP member country that is different from the Fellowship host country are eligible to apply for a Career Development Award. Long-Term Fellowships are for scientists with a Ph.D. degree in the life sciences who wish to broaden their experience through postdoctoral training abroad. Cross-Disciplinary Fellowships are intended for postdoctoral fellows with a Ph.D. degree in the physical sciences, chemistry, mathematics, engineering and computer sciences who wish to receive training in biology. Career Development Awards Career Development Awards are for former HFSP Long-Term or Cross-Disciplinary Fellows who return to their home country or move to an HFSP member country that is different from the host country of their HFSP Fellowship. The award provides support for initiating the fellows'' first independent laboratory., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Human Frontier Science Program (RRID:SCR_005112) Copy
http://snpeff.sourceforge.net/
Genetic variant annotation and effect prediction software toolbox that annotates and predicts effects of variants on genes (such as amino acid changes). By using standards, such as VCF, SnpEff makes it easy to integrate with other programs.
Proper citation: SnpEff (RRID:SCR_005191) Copy
http://gmt.genome.wustl.edu/somatic-sniper/current/
Software program to identify single nucleotide positions that are different between tumor and normal (or, in theory, any two bam files). It takes a tumor bam and a normal bam and compares the two to determine the differences. It outputs a file in a format very similar to Samtools consensus format. It uses the genotype likelihood model of MAQ (as implemented in Samtools) and then calculates the probability that the tumor and normal genotypes are different. This probability is reported as a somatic score. The somatic score is the Phred-scaled probability (between 0 to 255) that the Tumor and Normal genotypes are not different where 0 means there is no probability that the genotypes are different and 255 means there is a probability of 1 ? 10(255/-10) that the genotypes are different between tumor and normal. This is consistent with how the SAM format reports such probabilities. It is currently available as source code via github or as a Debian APT package.
Proper citation: SomaticSniper (RRID:SCR_005108) Copy
http://www.braintumorfunders.org/
The Brain Tumor Funders'' Collaborative is a partnership among five private philanthropic and advocacy organizations: American Brain Tumor Association, Brain Tumour Foundation of Canada, Children''s Brain Tumor Foundation, James S. McDonnell Foundation, and Sontag Foundation. This Collaborative promotes research directly relating to brain tumors and offers grants to professors and institutions to conduct research.
Proper citation: Brain Tumor Funders Collaborative (RRID:SCR_005104) Copy
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