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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.grnpedia.org/trrust/
TRUSST is reference database of human transcriptional regulatory interactions.TRRUST v2 is manually curated expanded reference database of human and mouse transcriptional regulatory interactions.
Proper citation: Transcriptional Regulatory Relationships Unrevealed by Sentence based Text mining database (RRID:SCR_022554) Copy
https://www.grnpedia.org/trrust/Network_search_form.php
Reference database of human transcriptional regulatory interactions. Manually curated database of human and mouse transcriptional regulatory networks.
Proper citation: TTRUST (RRID:SCR_022490) Copy
Generates, characterises and collects cell lines which are of interest for veterinary research and diagnostics. Collection includes cell lines of farm animals such as cattle, pig, horse, sheep, goat and poultry and other mammals, birds, reptiles, fishes and insects (70 species).Authentication and quality-control tests (tests for contamination with mycoplasms, bacteria, BVDV) of the cultures are done routinely.Cell cultures are provided to scientists of the Friedrich-Loeffler-Institute and other non-commercial institutions worldwide after consultation of a scientific staff member of the CCLV.
Proper citation: Collection of Cell Lines in Veterinary Medicine (RRID:SCR_023182) Copy
Comprehensive resource of neuropeptides, which holds non-redundant neuropeptide entries. Data collected from resources including MEDLINE abstracts, full papers, UniProt,database at www.neuropeptides.nl and Neuropedia. Contains detailed annotations for each entry, including source organisms, tissue specificity, families, names, post-translational modifications, 3D structures and literature references. Amino acid compositions, isoelectric points, molecular weight and other physicochemical properties of peptides are also provided. Search database with keywords such as sequence, name, family, etc.,User friendly web tools like browsing, sequence alignment and mapping are also integrated.Users can submit new entries online. Each new entry is validated before incorporating it.
Proper citation: NeuroPep (RRID:SCR_023102) Copy
Public knowledge base for information on evolutionary timescale of life. Data from thousands of published studies are assembled into searchable tree of life scaled to time.
Proper citation: TimeTree (RRID:SCR_021162) Copy
http://opig.stats.ox.ac.uk/webapps/newsabdab/sabdab/
Database containing all antibody structures available in the PDB, annotated and presented in consistent fashion.Each structure is annotated with number of properties including experimental details, antibody nomenclature (e.g. heavy-light pairings), curated affinity data and sequence annotations. You can use the database to inspect individual structures, create and download datasets for analysis, search the database for structures with similar sequences to your query, monitor the known structural repetoire of antibodies.
Proper citation: Structural Antibody Database (RRID:SCR_022096) Copy
https://grch38.warehouse.cmh.edu/
Database of non identifiable, summary data on all variants identified in Childrens Mercy Genomic Medicine Center, including project data of Genomic Answers for Kids. Database can be searched and viewed with genomic annotations, population database cross references such as ClinVar, gnomAD and dbSNP, ACMG curations and local allele frequency. Variant data are available for bulk download as annotated VCF.
Proper citation: CMH Variant Warehouse (RRID:SCR_021839) Copy
Gene atlas of Type 2 Diabetes Mellitus associated complex disorders. Provides curated and integrated information about genes involved in development and progression of Type 2 Diabetes Mellitus, genes and pathways with evidence for role in diabetes under risk factors including obesity, diet, inflammation, stress and complex disorders that are associated with Type 2 Diabetes Mellitus including atherosclerosis, diabetic retinopathy, diabetic nephropathy, diabetic neuropathy, cardiovascular disease.
Proper citation: T2DiACoD (RRID:SCR_019092) Copy
https://github.com/clinwiki-org/clinwiki
Clinical trials database.
Proper citation: ClinWiki (RRID:SCR_021297) Copy
https://portal.brain-map.org/explore/seattle-alzheimers-disease
Open atlas based on single cell profiling technologies with quantitative neuropathology and deep clinical phenotyping from middle temporal gyrus from neurotypical reference brains and brains from SEA-AD aged cohort that span spectrum of Alzheimer’s disease. Produced via collaboration between Allen Institute for Brain Science, University of Washington Alzheimer Disease Research Center and Kaiser Permanente Washington Health Research Institute.
Proper citation: Seattle Alzheimer Disease Brain Cell Atlas (RRID:SCR_023110) Copy
https://gitlab.com/rosen-lab/white-adipose-atlas
Single cell atlas of human and mouse white adipose tissue.
Proper citation: White Adipose Atlas (RRID:SCR_023625) Copy
Open online platform for single cell RNA-seq. Provides data management and analytics. Used to analyze public and private datasets and you can choose between several best practices workflows and browse existing analyses.
Proper citation: FASTGenomics (RRID:SCR_022898) Copy
https://www.girinst.org/repbase/
Database of repetitive DNA elements.Database of prototypic sequences representing repetitive DNA from different eukaryotic species. Used in genome sequencing projects worldwide as reference collection for masking and annotation of repetitive DNA.
Proper citation: Repbase (RRID:SCR_021169) Copy
https://rdrr.io/cran/WGCNA/man/BrainRegionMarkers.html
Software R package provides matrix of predefined set of marker genes for many regions of the human brain, using data from the Allen Human Brain Atlas.
Proper citation: BrainRegionMarkers (RRID:SCR_023836) Copy
https://github.com/benfulcher/GCEA_FalsePositives
Software toolbox for gene category enrichment analysis false positives available. Used for analysis of statistical biases in Gene Set Enrichment Analysis applied to transcriptomic atlas data.
Proper citation: GCEA_FalsePositives (RRID:SCR_023835) Copy
Open database of polygenic scores and relevant metadata required for accurate application and evaluation. Used for reproducibility and systematic evaluation.
Proper citation: Polygenic Score Catalog (RRID:SCR_023558) Copy
https://github.com/LeonDLotter/ABAnnotate/tree/v0.1.0
Software toolbox for ensemble-based multimodal gene-category enrichment analysis of human neuroimaging data.Performs ensemble-based gene-category enrichment analysis on volumetric human neuroimaging data via brain-wide gene expression patterns derived from Allen Human Brain Atlas. Utilizes nonparametric method using spatial autocorrelation-corrected phenotype null maps for estimation of gene-category null ensembles.
Proper citation: ABAnnotate (RRID:SCR_023833) Copy
Component of Accelerating Medicines Partnership Common Metabolic Diseases being developed at University of California San Diego as part of larger consortium of academic, industry and non-profit institutions worldwide. Resource is based on software developed by ENCODE DCC at Stanford University. Atlas provides epigenomics and other functional genomics data to promote understanding of genetic basis of common metabolic diseases.
Proper citation: Common Metabolic Disease Genome Atlas (RRID:SCR_022983) Copy
https://github.com/BlueBrain/atlas-densities
Software tools to compute densities in context of brain atlases. Used to create BBP Cell Atlas, using Allen Mouse Brain Atlas and collected literature density values.Provides list of volumetric files that provides cell type density estimates for each voxel of mouse brain volume.
Proper citation: Atlas Densities (RRID:SCR_023839) Copy
http://www.meduniwien.ac.at/allfam/
Database for classifying allergenic proteins into protein families.You can browse lists of allergen families restricted by allergen source (plants, animals, fungi, bacteria) and route of exposure (inhalation, ingestion etc.) or search for specific allergens, sources or protein families. Every allergen family entry is linked to description of biochemical properties and allergological significance of family members as well as list of key references related to this family.
Proper citation: AllFam (RRID:SCR_021276) Copy
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