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https://www.research.chop.edu/chop-microbiome-center

Core is sequencing and analytical resource of the PennCHOP Microbiome Program, providing end-to-end solutions for microbiome research. Sequencing lab offers expertise in next-generation DNA sequencing for microbiome studies, working with customers to provide optimized workflows and protocols customized for each study. Provides expertise in bioinformatics and statistical analysis of microbiome data. Develops an analytical plan specific to your project and can integrate microbiome data with other data sources, such as metabolomics or dietary intake information.

Proper citation: Children's Hospital of Philadelphia CHOP Microbiome Center Core Facility (RRID:SCR_028408) Copy   

•   Source: SciCrunch Registry

http://www.lvvc.be

Core provides services in design, construction, and production of custom research grade viral vectors for biomedical research including Adeno-associated viral (AAV) vectors, Retroviral vectors (MLV-based), Lentiviral vectors (LV), Virus-Like Particles (VLPs / Nanoblades).

Proper citation: Catholic University of Leuven Viral Vector Core Facility (RRID:SCR_028527) Copy   

•   Source: SciCrunch Registry

https://research.ncsu.edu/metric/

Molecular Education, Technology and Research Innovation Center (METRIC) is an NC State University-wide Shared Core Research Facility administered by the Office of Research and Innovation. We provide internal and external researchers with access to instrumentation and technical expertise across three primary analytical platforms: Mass Spectrometry: Supports qualitative and quantitative analyses, including high-resolution accurate mass (HRAM) measurements, proteomics, metabolomics, and small molecule analysis. Magnetic Resonance (NMR & EPR): Provides structural and dynamic characterization of molecules in solution. Capabilities include multi-nuclear solution-state NMR and Electron Paramagnetic Resonance (EPR) spectroscopy for studying paramagnetic species, transition metal complexes, and free radicals. X-Ray Diffraction: Offers atomic-level structural determination. The facility is equipped for single-crystal X-ray diffraction of both small molecules (including absolute configuration determination) and macromolecules/proteins.

Proper citation: North Carolina State University NCSU METRIC Core Facility (RRID:SCR_028548) Copy   

•   Source: SciCrunch Registry

https://www.shsu.edu/academics/colleges/science-engineering-technology/biological-sciences/microscopy-core-facility

Core provides specialized imaging services for primarily biological research, with additional applications for materials chemistry, forensic science, and engineering technology. Available instrumentation includes various light microscopes, a laser-scanning confocal, scanning and transmission electron microscopes, and X-ray imaging.

Proper citation: Sam Houston State University SHSU-Microscopy Core Facility (RRID:SCR_028477) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/cag-genotyping-core

Core is equipped with liquid handling technology and experienced staff members. Offers both standard and custom Illumina array project design. With the capacity to process >2300 samples/week and generate >480 million genotypes per day, the genotyping core fully integrates with our Biorepository and Bioinformatics group, offering the collaborator the opportunity for a seamless experience from DNA extraction to data release.

Proper citation: Children's Hospital of Philadelphia CHOP CAG Genotyping Core Facility (RRID:SCR_028400) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/single-cell-technology-core

Core offers services and access to single-cell, spatial and in situ technologies. Provides instruments, experienced research assistants and bioinformaticians to experimental and computational support. Services include 10x Genomics single cell assays, 10x Genomics Visium CytAssist and Visium HD spatial transcriptomics, 10x Genomics Xenium in situ spatial transcriptomics, Vizgen MERSCOPE in situ spatial transcriptomics, NanoString GeoMx Digital Spatial Profiler RNA and protein assays.

Proper citation: Children's Hospital of Philadelphia CHOP Single Cell Technology Core Facility (RRID:SCR_028401) Copy   

•   Source: SciCrunch Registry

https://www.ucl.ac.uk/mathematical-physical-sciences/chemistry/research/technical-services/transmission-electron-microscopy

Core for high resolution imaging and structural analysis of biological specimens, soft matter, and nanomaterials. Used to process samples from solution or powder, allowing researchers to visualize internal structures down to the subnanometer scale. It is critically important that the samples are non-magnetic.

Proper citation: University College London Mathematical and Physical Sciences Transmission Electron Microscopy Core Facility (RRID:SCR_028489) Copy   

•   Source: SciCrunch Registry

https://mcw.ilab.agilent.com/service_center/show_external/4967/cvc_core

Microscopy core managed by Cardiovascular Research Center. Operates as a teach and train service for confocal, slide scanning and general widefield fluorescence imaging.

Proper citation: Medical College of Wisconsin Cardiovascular Research Center CVRC Microscopy Core Facility (RRID:SCR_028523) Copy   

•   Source: SciCrunch Registry

https://mcw.ilab.agilent.com/service_center/show_external/4741/childrens_research_institute_cancer_center_flow_cytometry_shared_resource

Core provides access to analytical cytometers and cell sorters for trained users and operator-assisted cell sorting by appointment during business hours. Assists with protocol and assay development, including sample preparation, selection of antibodies and fluorochromes, proper staining and compensation controls, and selection of appropriate buffers. Offers assistance with data analysis using FlowJo, FCS Express, DIVA and SpectroFlo software is also available by appointment.

Proper citation: Medical College of Wisconsin Children's Research Institute Flow Cytometry Core Facility (RRID:SCR_028480) Copy   

•   Source: SciCrunch Registry

https://medicine.llu.edu/research/core-facilities/advanced-imaging-and-microscopy-core

Core offers microscopy services. Provides three offline analysis systems with Intel Xeon-based processors. Two of these are custom-built Origin computers and the third is a Dell Precision computer. All analysis workstations have the most recent versions of the Fiji build of Image J and RStudio.

Proper citation: Loma Linda University School of Medicine Advanced Imaging and Microscopy Core Facility (RRID:SCR_028455) Copy   

•   Source: SciCrunch Registry

http://NIC.botany.wisc.edu

Core provides services in confocal microscopy (CLSM, including FRET, ion imaging, and colocalization), scanning electron microscopy (SEM, including ESEM for wet samples), SEM prep instrumentation (critical point dryer and sputter coater), epifluorescence microscopy and polarizing microscopy.

Proper citation: University of Wisconsin Madison Newcomb Imaging Center NIC Core Facility (RRID:SCR_028453) Copy   

•   Source: SciCrunch Registry

https://mskcc.sharepoint.com/sites/pub-CoreFacilities/SitePages/Clinical-Grade-Production.aspx?e=nYjsKv

cGMP facility responsible for the bulk product manufacture, purification, and characterization of clinical-grade materials. Offers vialing of sterile investigational products such as peptides, proteins, carbohydrates, and adjuvants. Service also conducts lot release tests which are required for products release for preclinical and investigational use either in-house or with validated contract vendors.

Proper citation: Memorial Sloan Kettering Cancer Center MSKCC Clinical Grade Production Core Facility (RRID:SCR_028454) Copy   

•   Source: SciCrunch Registry

https://www.ouhealth.com/stephenson-cancer-center/cancer-research/cancer-shared-resources-services/tissue-pathology-biospecimen-shared-resource/

Core provides tissue processing, histology and staining services. Services include embedding, sectioning, histochemical staining of mounted slides, immunohistochemical (IHC) staining for paraffin embedded and frozen tissues, immunocytochemical (ICC) staining for cultured cells (as tissue sections or cytospin slides), evaluation of new antibodies for IHC staining, enzyme histochemistry and special staining.Provides defined analyses including RNA / DNA preparation, reverse transcription and cDNA synthesis from total RNA, construction, staining and analysis of tissue microarrays, and construction and analysis of reverse proteomics array from user-defined biospecimens.Core is flexible to accommodate the development of new techniques and expanding its services based on the research requirements of SCC members and other investigators.

Proper citation: University of Oklahoma Health Sciences Center Tissue Pathology and Biospecimen Core Facility (RRID:SCR_028452) Copy   

•   Source: SciCrunch Registry

https://rtsf.natsci.msu.edu/proteomics/index.aspx

Core provides mass spectrometry resources and expertise to assist researchers in the identification and characterization of proteins and peptides. Experiments from simple protein discovery to complex differential proteome profiling, post-translational modification mapping and protein/peptide quantification can be performed using our instrumentation and software.

Proper citation: Michigan State University Proteomics Core Facility (RRID:SCR_028467) Copy   

•   Source: SciCrunch Registry

https://www.research.chop.edu/chop-high-throughput-sequencing-core

Core is service facility providing instrumentation, library preparation, and sequencing services to CHOP, UPenn, and external investigators in genomic, epigenomic and transcriptomic studies.

Proper citation: Children's Hospital of Philadelphia CHOP High Throughput Sequencing Core Facility (RRID:SCR_028398) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/about/research-integrity.html

Core enables and promotes responsible research practices to generate trustworthy data, and to safeguard research data. The service is comprised of 4 pillars; governance, good research practice support, stewardship and knowledge exchange.

Proper citation: Cancer Research UK Scotland Institute Research Integrity Service Core Facility (RRID:SCR_028431) Copy   

•   Source: SciCrunch Registry

https://cores.research.utdallas.edu/imaging-and-histology-core/

Core Facility is located in the Natural Science and Engineering Research Laboratory. Provides support for basic and translational research in biological and interdisciplinary sciences through its instruments. Core has advanced imaging systems including confocal microscopes, high-throughput slide scanner, multiphoton intravital microscope, electron microscopes, and various other optical instruments. Houses workstations equipped with advanced image analysis software such as Imaris and cellSens Dimension. Provides support for processing and embedding of tissue samples, sectioning and slide preparation, and cell culture.

Proper citation: University of Texas at Dallas UTD Imaging and Histology Core Facility (RRID:SCR_028553) Copy   

•   Source: SciCrunch Registry

https://uwhistologyandimaging.org/

Core provides histology, immunohistochemistry, imaging, quantitative image analysis, and pathology consultation services. Offers experience, expertise and instrumentation across all platforms. Through the partnership with the Comparative Pathology Program (CPP), we have board certifies veterinary pathologists on staff who are available for research consultation and collaboration.

Proper citation: University of Washington Histology and Imaging Core Facility (RRID:SCR_028435) Copy   

•   Source: SciCrunch Registry

https://elektronenmikroskopie.charite.de/

Core provides electron microscopy services including Sample preparation from tissues, cell culture, cell suspension; Sample preparation for materials science; Preparation of semi-thin sections; Preparation of ultrathin sections for classical TEM , REM and serial reconstruction;Contrast methods for TEM samples, SEM samples, negative contrast, coating methods for SEM; Classical TEM and REM; Immunogold technique;Tokuyasu freeze-cutting technique; Cryo-substitution; Cryo-electron microscopy; Electron tomography; 3D array tomography; SBF-SEM; Image documentation and digital processing; Technical-preparative adjustments; Provision of infrastructure (sample preparation, electron microscopes, individual user training); Creating image documentation and evaluations; Image processing techniques and quantitative evaluation techniques (Image J, Fiji/TrakEM2, IMOD/3Dmod, Amira 5, ZEN Connect, etc.); Publication consulting.

Proper citation: Charité Berlin University of Medicine Electron Microscopy Core Facility (RRID:SCR_028563) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/about/use-of-animals-in-our-research.html

Core facility provides technical services including transgenic breeding, chemical carcinogenesis treatment, tumourigenicity studies in nude mice and quarantine facilities to allow the import of animals from both Europe and other countries.

Proper citation: Cancer Research UK Scotland Institute Biological Services Core Facility (RRID:SCR_028654) Copy   

•   Source: SciCrunch Registry