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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.biotech.wisc.edu/facilities/brc/home
Facility within UW Biotechnology Center (UWBC) for assisting researchers with their data analysis needs. Helps with variety of common sequencing related projects, DNA-seq, ChIP-Seq, RNA-Seq, 16S metagenomics, and small RNA analyses.
Proper citation: Wisconsin-Madison University Biotechnology Center Bioinformatics Resource Center Core Facility (RRID:SCR_017799) Copy
https://med.psu.edu/core/mass-spectrometry
Core provides mass spectrometry analyses and identification of proteins, peptides, oligonucleotides, carbohydrates and small molecules.Other services include separations of complex protein and/or peptide mixtures; protein expression analysis (iTraq, SILAC, SWATH/DIA label-free); quantitation of protein, cytokine, amino acid and other small-molecule levels; bioinformatics; spot-cutting and robotics; and gel imaging and analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: Penn State College of Medicine Mass Spectrometry and Proteomics Core Facility (RRID:SCR_017831) Copy
http://sites.northwestern.edu/htal/
Core provides expertise and resources for large scale biology. Helps to set up, run, gather data and perform analysis in drug discovery research, biochemistry, cell and organismal biology, functional genomic screening, and synthetic genetic. Works with proteins, nucleic acids, small model organisms, and microbial strains. Provides tissue culture,produces and uses lentivirus particles, screens compound libraries, does experiments for investigators,generates preliminary data to figure out if idea is workable, discusses project development. Services include Macromolecular binding, biochemical, and cell-based assays,High content screening with widefield or confocal optics,Nanoliter liquid handling up to 1536-well density,Whole-plate kinetic assays (ion currents, GPCR signaling),Compound library screening,CRISPR/Cas9 screening (multiplexed libraries),Analysis of large data sets,Fluorescence Thermal Shift assay (measures protein melting),Complex liquid handling work flows.
Proper citation: Northwestern University High Throughput Analysis Laboratory Core Facility (RRID:SCR_017879) Copy
Core provides access to NMR technology. Users can collect their own data, facility staff can do it all for you, or collaborative projects can be developed. Provides training in instrument operation and can offer advice for data analysis or project feasibility. Facility houses two 600 MHz Bruker Avance III spectrometers with cryogenically cooled probes.
Proper citation: University of California San Diego Skaggs School of Pharmacy and Pharmaceutical Sciences NMR Core Facility (RRID:SCR_017919) Copy
Core provides access to advanced chromatographic and mass spectrometry instrumentation. Main analytical focus is quantitative analysis of small molecules (drugs, drug metabololites, endogenous metabolites, xenobiotics and toxicants) and intact large molecules (biologics, intact proteins, and biopolymers like hyaluronan). Provides analytical instruments including Liquid Chromatography and Mass Spectrometry, Microbalances, Quantitative PCR (qPCR or Real-Time PCR), Sample Preparation Aids, Pharmacology Department Shared Instruments.
Proper citation: Kansas University Medical Center Analytical Core Facility (RRID:SCR_017888) Copy
https://www.brown.edu/research/facilities/flow-cytometry-and-sorting/home
Core provides technical assistance to Brown researchers by performing flow cytometry-based analysis and sorting. Facility has 4-laser, 19-parameter BD FACSAria IIIu for flow and sorting applications, as well as 3-laser, 15-parameter BD FACSCelesta equipped with high throughput system for analysis of samples from 96 well plates.
Proper citation: Brown University Flow Cytometry and Sorting Core Facility (RRID:SCR_017886) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/proteomics-laboratory
Core offers specialized expertise for analysis of proteins and peptides using mass spectrometry. Develops new methods and customized approaches for proteomic analysis and suggests experimental strategies and sample preparation prior to mass spectrometry analysis. Services include:comprehensive protein identification ,analysis of affinity purified complexes,characterizing protein post-translational modifications,de novo sequencing,label and label-free quantitation ,multiplexed quantitation global phosphorylation and ubiquitin analysis,analysis of laser-capture microdissected formalin-fixed paraffin-embedded tissue,secretome analysis,crosslinking analysis,disulfide mapping.
Proper citation: New York University School of Medicine Langone Health Proteomics Laboratory Core Facility (RRID:SCR_017926) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/genome-technology-center
Core provides range of services related to genome, epigenome, and transcriptome analysis. Offers technologies including Illumina deep sequencing and sample preparation for variety of applications, including DNA and RNA sequencing (DNA- and RNA-seq), exome sequencing, targeted capture, chromatin immunoprecipitation sequencing (ChIP-seq), methylation sequencing (Methyl-seq), metagenomics, and many others;Automation of Illumina library and targeted capture preps, including 16S ribosomal RNA (rRNA) sequencing;Oxford Nanopore sequencing (long reads);Bio-Rad Droplet Digita polymerase chain reaction (PCR);Nanostring nCounter;Single-cell RNA- and DNA-seq using the C1 Auto Prep System from Fluidigm, and 10x Genomics Chromium System.Provides expertise on strategies to achieve research goals in any field related to genomics, and can tailor bioinformatics analysis to individual project. If you supply us with nucleic acids, we can perform every step required to help you achieve your desired results.
Proper citation: New York University School of Medicine Langone Health Genome Technology Center Core Facility (RRID:SCR_017929) Copy
Core provides liquid chromatography and gas chromatography mass spectrometry instrumentation for selective identification and reproducible quantification of trace-level biomolecules in complex samples. Services include qualitative, quantitative and structural analysis of proteins, lipids, metabolites, pesticides, pharmaceuticals and volatile organic compounds. Tests can be performed as long as molecules of interest are amenable to ionisation technique employed in source of mass spectrometer. Depending on instrument type, samples may be solid, liquid or gas. Mass spectrometry platforms include Liquid Chromatography Mass Spectrometry (LC-MS) and Gas Chromatography Mass Spectrometry (GC-MS). Analysis include volatile organic compounds (odour analysis),pharmacokinetics (bioavailability, bioefficacy),drug development (determining structures of drugs and metabolites),clinical testing (biomarkers discovery and endogenous compounds),genomics (oligonucleotide sequencing) epigenetics (global DNA methylation analysis),environmental research (testing water, soil, food and air quality).
Proper citation: Queensland University of Technology Central Analytical Research Facility (CARF) Proteomics and Small Molecule Mass Spectrometry Core Facility (RRID:SCR_017933) Copy
Open access core facility available to all TAMU users for Metabolomics service and research. Provides different levels of service from drop-off to collaborative projects.Training for TAMU postdoctoral fellows and students to use instrumentation in support of specific projects.Short courses and workshops on advances in metabolomics. Instrumentation for targeted and untargeted metabolomics analysis.Provides mass spectrometers that are coupled to liquid chromatography (LC) or gas chromatography (GC) separation systems.
Proper citation: Texas A&M University Integrated Metabolomics Analysis Core Facility (RRID:SCR_017897) Copy
http://web.mit.edu/flowcytometry/www/
Core provides technical expertise, training and access to instrumentation, enabling and supporting use of flow cytometry techniques. Allows simultaneous multiparametric analysis of many thousands of cells per second, enabling trained researchers to rapidly analyze complex cell populations using benchtop analysis flow cytometers. High-speed assisted cell sorting services provide researchers with fast, objective and quantitative recording of fluorescent signals from individual cells combined with physical separation of cells of particular interest.Services include High-end, staff assisted cell sorting, using four different high speed sorters;Unassisted bench-top analysis available 24/7;Assisted bench-top analysis available by appointment;Extensive training on bench-top analyzers;Extensive training on FACS Aria sorters;Consultation on experimental design and data interpretation.
Proper citation: Massachusetts Institute of Technology Koch Institute Flow Cytometry Core Facility (RRID:SCR_017892) Copy
https://www.brown.edu/research/facilities/bioimaging/
Core provides equipment and training dedicated to high resolution imaging in life sciences. Facility includes Transmission Electron Microscope, a Scanning Electron Microscope, three Fluorescence Microscopes, Fluorescence Stereomicroscope, four Confocal Laser Scanning Microscopes,Multiphoton Microscope, and software for image analysis.Maintains equipment for sample preparation, including critical point dryer, sputter coater, and microtomes for ultrathin sectioning. Listed within CoresRI.org.
Proper citation: Brown University Leduc Bioimaging Core Facility (RRID:SCR_017861) Copy
Core provides Next Generation Sequencing and Bioinformatics services.Services include:RNA assessment using Agilent 2100 Bioanalyzer,Next Generation Sequencing:Single cell RNA-seq,DNA-seq,RNA-seq,miRNA-seq,ChIP-seq,Microbiome (16S rRNA),ATAC-seq,Data Analysis (Partek Flow, Transcription Analysis Console).
Proper citation: London Regional Genomics Centre Core Facility (RRID:SCR_017865) Copy
http://hormone.facilities.northwestern.edu
Core provides hormone analyses for both human and animal studies for scientific community at Northwestern, small rodent metabolic phenotyping resources for diabetes, obesity and other metabolic research.Maintains quality control and standardize internal references for hormone assays.Maintains reference database information on mouse metabolic phenotyping models from Northwestern University community.Services include:Immunoassays for endocrine hormones, assays using technology from Luminex,Lipid and glucose chemical analyeses,Roche Cobas e 411 analyzer employing sophisticated electrochemiluminescence (ECL) technology to deliver excellent low-end sensitivity and broad dynamic range of assays including metabolic and reproductive hormones, thyroid function test, cardiac markers, maternal care, tumor markers and bone turnover markers.,TSE LabMaster Automated Phenotyping system is a state-of-the-art system for studying energy metabolism at whole animal level.
Proper citation: Northwestern University Comprehensive Metabolic Core Facility (RRID:SCR_017871) Copy
http://www.nationwidechildrens.org/genomics
Core performs and analyzes integrated clinical genomic, molecular, microarray, FISH, and cytogenetic analyses to diagnose broad range of inherited diseases and cancer. Serves as centralized clinical testing laboratory for Children Oncology Group leukemia, Wilms tumor, medulloblastoma, and rhabdomyosarcoma studies. Emphasizes collaborative interactions between clinicians, physician-scientists, and basic science investigators to quickly transition cutting edge research results into cutting edge diagnostics, using technology platforms. Services include Whole Exome Sequencing (WES),cytogenetic chromosome analysis,Fluorescence in situ Hybridization,Chromosomal microarray analysis,Molecular Genetic Testing - Inherited Diseases,Molecular Genetic Testing - Cancer.
Proper citation: Steve and Cindy Rasmussen Institute for Genomic Medicine Clinical Laboratory Core Facility at Nationwide Children�s Hospital (RRID:SCR_017840) Copy
http://www.mpi-cbg.de/facilities/profiles/ht-tds.html
Provides expertise in assay development towards high-throughput applications and high content screening services, provides technologies for cell-based screening such as robotic liquid handling stations, plate readers and several automated microscopes. Services include developing complex automated image analysis pipelines and multi-parametric analysis of high content imaging applications.Equipment:Flexible liquid handling work stations Biomek FXp (Beckman), Freedom Evo 200 (TECAN);Multilabel microtiter plate readers Envision (Perkin Elmer), GENios Pro (TECAN);Acoustic dispensing (Labcyte Echo 550);CellVoyager CV7000 automated live cell confocal microscope (Yokogaw);Perkin Elmer OPERA;Operetta widefield microscope (Perkin Elmer);Automated confocal microscopy OPERA (Perkin Elmer);Washers, dispensers;96-well electroporation system (amaxa nucleofector).
Proper citation: Max-Planck-Institute for Molecular Cell Biology and Genetics High Throughput Technology Development Studio Core Facility (RRID:SCR_017842) Copy
http://www.garvan.org.au/research/capabilities/molecular-genetics
Core facility for high throughput services covering the areas of Capillary Sequencing, Mouse Genotyping, SNP Genotyping, Clinical Diagnostic Sequencing, Cell Line Identification, Gene Expression Analysis and DNA/RNA extraction.
Proper citation: Garvan Institute of Medical Research Molecular Genetics Core Facility (RRID:SCR_017849) Copy
http://www.scripps.edu/florida/technologies/metaboliccore/index.html
Core provides researchers with equipment and expertise required for multi-dimensional imaging of cells and tissues at high resolution and to perform quantitative image analysis. Resources include widefield, confocal, multi-photon, TIRF, super-resolution and electron microscopy, as well as equipment for live cell imaging and image analysis. Services include sample preparation, imaging, molecular localization, and image analysis. Provides training, technical support, sample preparation, imaging assistance, collaboration and consultation.
Proper citation: Scripps Research Institute - Florida Core Microscopy Core Facility (RRID:SCR_017848) Copy
http://www.mskcc.org/research/molecular-cytogenetics
Core supports cytogenetic analysis of cells from human and research animal sources. Range of chromosome analysis techniques are ranging from basic G-banded karyotyping, to 24-color Spectral Karyotyping (SKY), as well as Fluorescence in situ Hybridization (FISH) mapping of cloned DNAs.Services include:Karyotype characterization of new cell lines,Confirmation of cell line identity or stability,Karyotype screening of ES cells prior to transgenesis,Mapping of transgene integration sites,Chromosome or locus copy number enumeration,Publication-quality illustrations.Cytogenetic techniques available:Short-term cell culture,Metaphase chromosome preparation,G-banded karyotyping.FISH techniques available:DNA labeling for custom probe generation (for FISH projects),DNA amplification by DOP-PCR,Chromosome painting,FISH mapping (on chromosomes, interphase nuclei or DNA fibers),Tissue FISH (paraffin or frozen sections),Immuno-FISH (DNA FISH combined with fluorescent immunostaining) , Spectral karyotyping (SKY),Q-FISH (measurement of telomere lengths).
Proper citation: Memorial Sloan Kettering Cancer Center Molecular Cytogenetics Core Facility (RRID:SCR_017850) Copy
https://my.ilabsolutions.com/service_center/show_external/4003
Core specializes in cell, protein, and small molecules analysis as well as cell culture techniques. Services include:2-D gel electrophoresis, 2-D DIGE, LC-MS/MS, HPLC, flow cytometry, fluorescence-activated cell sorting (FACS), cell and tissue culture, and immortalization of cell lines. Our staff works closely with investigators to help design, perform, and analyze experiments.Offers training and assistance in flow cytometry, tissue culture, and operation many of our walk-up instruments.Instruments:Cell Sorter: FACS Aria III, BD Biosciences;Flow Cytometers, analyzers:C6, Accuri/BD Biosciences;Novocyte 3000, ACEA Biosciences;software for analysis: FSC Express, DeNovo software;LC-MS/MS: 6460 Triple Quadrupole, Agilent;Typhoon Trio Scanner, GE Lifesciences;Blood Analyzer: Hemavet 950, Drew Scientific.Plate Readers:;Victor Nivo 5F, Perkin Elmer;Luminometer: Centro XS, Berthold.Services:Cell Sorting (FACS);2-D gel electrophoresis/2D-DIGE;LC-MS/MS analysis of compounds; Cell immortilization.
Proper citation: Nemours/A.I.duPont Hospital for Children Cell Science Core Facility (RRID:SCR_017854) Copy
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