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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www2.jabsom.hawaii.edu/mousecore/
Core provides murine echocardiography, blood pressure determinations, surgical procedures and phlebotomy, as well as assistance with mouse husbandry and genotyping.
Proper citation: Hawaii University School of Medicine Mouse Phenotyping Core Facility (RRID:SCR_017753) Copy
Research oriented service laboratory providing informatics support to research community. Services include data analysis and mining in proteomics, genomics and chemistry, systems biology approaches such as pathway, network and interaction analyses, large scale statistical and machine learning studies, protein structure, function and stability prediction, sequence and domain analyses,d esign and implementation of relational databases and software programs, consultation on experimental design involving data acquisition, management and analysis, report, grant, and manuscript preparation.
Proper citation: Kansas University at Lawrence Applied Bioinformatics Laboratory Core Facility (RRID:SCR_017751) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/mgec/index.html
Core Facility provides expertise and advice for experimental design of transgenic or gene knockout experiments, including DNA construct production and genotyping assays, makes reagents available for generation of transgene or gene targeting constructs, and performs all experimental aspects, which include pronuclear injection of transgene constructs, generation of recombinant mouse ES cells, blastocyst injection, and embryo transfer surgeries, for generation or rederivation of genetically manipulated mouse strains. Transgenic founder mice or chimeric animals with targeted alleles are then transferred to individual investigator for analysis.
Proper citation: Nebraska University Medical Center Mouse Genome Engineering Core Facility (RRID:SCR_017755) Copy
http://www.dartmouth.edu/emlab/
Provides electron microscopy services for faculty, staff and students of Dartmouth College community, including College, Thayer School of Engineering, Dartmouth Medical School, and Dartmouth-Hitchcock Medical Center. Provides training about how to use instruments and service assistance available for those unable to spend time on microscopes, and for processing of biopsy samples from DHMC.
Proper citation: Darthmouth College Electron Microscope Core Facility (RRID:SCR_017754) Copy
http://www.med.unc.edu/csb/unc-peptides
Core offers services for: High quality synthetic peptides, stable isotope labeled peptides, peptides with PTM and fluorescent and affinity tags, synthesis of peptide libraries. Analysis of synthetic peptides. Purification, lyophilization and aliquoting of synthetic peptides.
Proper citation: North Carolina University at Chapel Hill School of Medicine High Throughput Peptide Synthesis and Array Core Facility (RRID:SCR_017837) Copy
https://www.med.unc.edu/csb/mx/
Core provides support and infrastructure necessary to initiate and successfully complete structural biology or structural chemistry project. Offers services in Crystallization,X-Ray DiffractionData Collection,Structure Determination and Refinement.
Proper citation: North Carolina University at Chapel Hill School of Medicine Macromolecular X-Ray Crystallography Core Facility (RRID:SCR_017839) Copy
Core provides services and houses samples collected over the last 30 years. Biorepository processes, archives, and retrieves biological samples for genomic research. Offers variety of sample processing options including but not limited to automated DNA extraction using Autogen FLEXSTAR+ instrument, automated DNA/RNA extraction using Qiagen QIASymphony, peripheral blood mononuclear cell (PBMC) isolation, serum, plasma and buffy coat isolation, creation of blood cards, DNA/RNA quantitation and qualitation, whole genome amplification, cell-line lymphoblast immortalization and primary fibroblast tissue culture. Offers sample solutions tos uit customized needs.Services also include DNA/RNA Extraction,Sample archiving, retrieval and allocation,Unique and custom labels printing,DNA/RNA quantitation and qualitation,Tissue culture,Whole genome amplification.
Proper citation: University of Miami Hussman Institute for Human Genomics Biorepository Core Facility (RRID:SCR_017816) Copy
http://bioimaging.dbi.udel.edu
Microscopy facility that houses equipment including confocal microscopes: LSM780 confocal microscope (Located at CBBI),LSM880 confocal microscope (Located at DBI 117),electron microscopes and their accessory instrumentation:Thermo Scientific Apreo VS SEM microscope,Hitachi S-4700, Leica EM ACE600 and Tousimis Autosamdri-815B,CX7 high content analysis system. Our staff has technical expertise across different microscopy platforms and methodologies.
Proper citation: University of Delaware BioImaging Center Core Facility (RRID:SCR_017814) Copy
https://chemistry.as.miami.edu/research-facilities/mass-spectrometry-laboratory/index.html
Core provides two mass spectrometers at UM Department of Chemistry, Bruker MicroQ-TOF ESI, and Agilent Technologies 5975C GC/MS with autosampler.
Proper citation: Miami University Mass Spectroscopy Laboratory Core Facility (RRID:SCR_017819) Copy
http://www.kumc.edu/mspc.html/
Core provides access to mass spectrometry based proteomics applications, customizes mass spectrometry designs that fit individual needs. Used for general proteomics evaluations and protein identification designs, quantitation techniques, hydrogen/deuterium exchange, and oxidative footprinting. Equipment includes Orbitrap Fusion Lumos.
Proper citation: Kansas University Medical Center Mass Spectrometry/Proteomics Core Facility (RRID:SCR_017818) Copy
http://www.umassmed.edu/QHS/QMC.aspx?linkidentifier=id&itemid=90142
Provides University of Massachusetts Medical School investigators with clinical research support in biostatistics, experimental design, and data management.
Proper citation: Massachusetts University Medical School Quantitative Methods Core (RRID:SCR_017786) Copy
Provides system for Splicing isoform Annotation. This LISA platform allows high throughput annotation and functional analysis of Alternate Splicing in humans.
Proper citation: Quebeck Sherbrooke University Genomic Core Facility (RRID:SCR_017785) Copy
http://www.ubnextgencore.buffalo.edu
Core sequencing services include Illumina Sequencers, Single-Cell RNA-Seq,Single-Cell Immune Profiling,Single-Cell ATAC-Seq,Linked-Read Sequencing. Provides bioinformatic analysis including Single-Cell RNA Analysis,Linked-Read Genome Analysis,ChIP-Seq Analysis Package,RNA-Seq Analysis Package,miRNA Analysis Package,Custom Project Requests,A La Carte Bioinformatics. Provides services including QX100 Droplet Digital PCR Machine (Biorad),Nucleic acid extractions from bio-specimens, Sample QC,Realtime PCR.
Proper citation: Buffalo University Genomics and Bioinformatics Core Facility (RRID:SCR_017784) Copy
https://www.danforthcenter.org/scientists-research/core-technologies/tissue-culture-transformation
Facility operates as full service facility delivering transgenics and cell cultures to researchers and self service facility providing high quality space for researchers to use for their own specific project needs. Services available include transformations and cell/ tissue culture in many different plant species, project consultation, training workshops, self-service hood usage and offering high quality growth space. Facility staff has developed portfolio of transformation and tissue culture systems such as: Setaria, tobacco, petunia, tomato, Arabidopsis, soybean, Indian mustard, maize, rice and various different cell cultures. Within the facility, researchers have also produced cassava, sweet potato, and potato. Transformation systems will be added, developed, inherited, or modified as needed.
Proper citation: Donald Danforth Plant Science Center Tissue Culture and Transformation Core Facility (RRID:SCR_017783) Copy
https://www.aicjanelia.org/about
Facility provides imaging methods and instruments, microscopes that reveal biological processes in three-dimensional detail and behavior of single molecules in high resolution. Welcomes proposals with high-risk/high-gain projects. AIC will cover lodging and basic experimental cost for scientists whose proposals have been accepted to come to Janelia to perform their experiments.
Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Advanced Imaging Center Core Facility (RRID:SCR_017823) Copy
http://cpl.med.miami.edu/services/
Full service veterinary reference laboratory directed by members of faculty of University of Miami Miller School of Medicine. Offers clinical pathology and histopathology services to meet needs of avian, exotic, lab animal, and wildlife veterinarians. Services include Acute Phase Protein Laboratory. Provides recent diagnostic testing developments which may not yet be available in other veterinary diagnostic testing environments.
Proper citation: Miami University Veterinary Clinical Pathology Laboratory Core Facility (RRID:SCR_017822) Copy
http://microscopy.stanford.edu
Provides high resolution, light and electron microscopy technologies for imaging and analyzing molecular and structural organization of cells, tissue and bioengineered materials. Operates two sites at Stanford University: SOM Beckman Center CSIF and SOE Shriram Center CSIF.
Proper citation: Stanford University Cell Sciences Imaging Core Facility (RRID:SCR_017787) Copy
http://hihg.med.miami.edu/cgt/genotyping
Core provides services in analyzing genetic variation, performing genome-wide association studies, conducting non-human genotyping. Offers flexible platforms from low to high throughput, tailored to research needs. Specializes in Illumina Genotyping Arrays and TaqMan Allelic Discrimination Assays, with fully automated processing using Tecan EVOs and BioMek liquid handlers and Genologics LIMS for reliable data tracking.Applications include: GWAS – Identify genetic variants linked to traits and diseases; PRS Analysis – Assess genetic risk for complex diseases; Pharmacogenomics – Study genetic factors in drug response; Population Genetics – Explore ancestry and genetic diversity; CNV Analysis – Detect large-scale genomic variations; Methylation Analysis.
Proper citation: University of Miami Hussman Institute for Human Genomics Genotyping Core Facility (RRID:SCR_017820) Copy
http://www.protein.iastate.edu
Core offers protein/peptide sequencing, large and small scale peptide synthesis (Fmoc), matrix assisted laser desorption/ionization (MALDI) mass spectrometry, SDS-PAGE/electroblotting, 2-D gel electrophoresis, isoelectric focusing (IEF), in-gel and solution digestion, tandem mass spectrometry (LC-MS/MS), ion mobility mass spectrometry (IM-MS), digital image acquisition and analysis using Typhoon imaging system and 2D gel documentation/analysis system, and semi-preparative, analytical and micro-analytical high performance liquid chromatography (HPLC). MALDI, HPLC, SDS-PAGE/blotting, IEF, 2D gel electrophoresis, 2D gel documentation/analysis and Typhoon imaging system are all available for user operation after appropriate training.
Proper citation: Iowa State University Office of Biotechnology Protein Core Facility (RRID:SCR_017780) Copy
https://wertheim.scripps.ufl.edu/cores-and-technologies/genomics-core/
Core provides services in Next Generation Sequencing (NGS), library preparation, consultation on sample preparation and procedures.
Proper citation: Herbert Wertheim University of Florida Scripps Institute for Biomedical Innovation and Technology Genomics Core Facility (RRID:SCR_017827) Copy
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