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https://www.crukscotlandinstitute.ac.uk/about/research-integrity.html

Core enables and promotes responsible research practices to generate trustworthy data, and to safeguard research data. The service is comprised of 4 pillars; governance, good research practice support, stewardship and knowledge exchange.

Proper citation: Cancer Research UK Scotland Institute Research Integrity Service Core Facility (RRID:SCR_028431) Copy   


https://cores.research.utdallas.edu/imaging-and-histology-core/

Core Facility is located in the Natural Science and Engineering Research Laboratory. Provides support for basic and translational research in biological and interdisciplinary sciences through its instruments. Core has advanced imaging systems including confocal microscopes, high-throughput slide scanner, multiphoton intravital microscope, electron microscopes, and various other optical instruments. Houses workstations equipped with advanced image analysis software such as Imaris and cellSens Dimension. Provides support for processing and embedding of tissue samples, sectioning and slide preparation, and cell culture.

Proper citation: University of Texas at Dallas UTD Imaging and Histology Core Facility (RRID:SCR_028553) Copy   


https://uwhistologyandimaging.org/

Core provides histology, immunohistochemistry, imaging, quantitative image analysis, and pathology consultation services. Offers experience, expertise and instrumentation across all platforms. Through the partnership with the Comparative Pathology Program (CPP), we have board certifies veterinary pathologists on staff who are available for research consultation and collaboration.

Proper citation: University of Washington Histology and Imaging Core Facility (RRID:SCR_028435) Copy   


https://elektronenmikroskopie.charite.de/

Core provides electron microscopy services including Sample preparation from tissues, cell culture, cell suspension; Sample preparation for materials science; Preparation of semi-thin sections; Preparation of ultrathin sections for classical TEM , REM and serial reconstruction;Contrast methods for TEM samples, SEM samples, negative contrast, coating methods for SEM; Classical TEM and REM; Immunogold technique;Tokuyasu freeze-cutting technique; Cryo-substitution; Cryo-electron microscopy; Electron tomography; 3D array tomography; SBF-SEM; Image documentation and digital processing; Technical-preparative adjustments; Provision of infrastructure (sample preparation, electron microscopes, individual user training); Creating image documentation and evaluations; Image processing techniques and quantitative evaluation techniques (Image J, Fiji/TrakEM2, IMOD/3Dmod, Amira 5, ZEN Connect, etc.); Publication consulting.

Proper citation: Charité Berlin University of Medicine Electron Microscopy Core Facility (RRID:SCR_028563) Copy   


https://www.crukscotlandinstitute.ac.uk/about/use-of-animals-in-our-research.html

Core facility provides technical services including transgenic breeding, chemical carcinogenesis treatment, tumourigenicity studies in nude mice and quarantine facilities to allow the import of animals from both Europe and other countries.

Proper citation: Cancer Research UK Scotland Institute Biological Services Core Facility (RRID:SCR_028654) Copy   


https://web.uri.edu/riinbre/core-facility/

Core offers research instrumentation for hands-on use to researchers. Provides molecular biology, analytical, and imaging instruments to serve RI’s biomedical scientists totaling 3800 sq. ft. in the URI College of Pharmacy building.

Proper citation: University of Rhode Island RI-INBRE Centralized Research Core Facility (RRID:SCR_028658) Copy   


https://www.medizin.rwth-aachen.de/cms/medizin/forschung/forschungsinfrastruktur/core-facilities/~qehj/genomics-facility/?lidx=1

Core provides Next Generation Sequencing (NGS) expertise and services including nucleic acid sample extraction, quantification, RT-qPCR and Quality Control (QC), experimental design, advanced data analysis.

Proper citation: RWTH Aachen University Genomics Facility of the Interdisciplinary Center for Clinical Research IZKF Core Facility (RRID:SCR_028662) Copy   


https://www.medizin.rwth-aachen.de/go/id/pupf

Proteomics Facility is the centralized service unit of the Medical Faculty of RWTH Aachen University for the analysis of proteome samples. Offers sample preparation and mass spectrometric analysis, as well as bioinformatic processing of raw data (identification and quantification) of peptides and proteins, along with functional bioinformatic analysis of the resulting datasets.

Proper citation: RWTH Aachen University Proteomics Facility of the Interdisciplinary Center for Clinical Research IZKF Core Facility (RRID:SCR_028663) Copy   


https://www.medizin.rwth-aachen.de/cms/medizin/forschung/forschungsinfrastruktur/core-facilities/~btmfsz/light-microscopy-facility/?lidx=1

Core supports researchers in the use of modern light microscopy systems. Provides advanced optical imaging equipment, technical expertise, and hands-on training for biomedical and clinical research projects. Microscope platforms include confocal and multiphoton microscopy for imaging fluorescently labeled structures to enable the investigation and characterization of cells, tissues, organisms, and biomaterials with high spatial and temporal resolution.

Proper citation: RWTH Aachen University Light Microscopy Facility of the Interdisciplinary Center for Clinical Research IZKF Core Facility (RRID:SCR_028667) Copy   


https://www.cruk.cam.ac.uk/core-facilities/pre-clinical-genome-editing/

Core facility provides genome editing services in vitro and in vivo for translational cancer research. Services span functional genomics (CRISPR screens across cells, organoids and patient-derived xenograft models, integrated with single-cell RNA sequencing), transgenics (embryo manipulation, pronuclear injection, electroporation, cryopreservation, and import/export of genetically modified models), and multimodal pre-clinical trials run through a dedicated Small Animal Hospital using genetically engineered, xenograft and orthotopic models. Offers experimental design consultation to match editing technologies to each research question.

Proper citation: Cancer Research UK Cambridge Institute Pre-Clinical Genome Editing Core Facility (RRID:SCR_028661) Copy   


https://www.umt.edu/genomics-lab/default.php

Core is multi-user and service laboratory that offers comprehensive genetic and genomic services. Provides expert consultation, grant application support, training, and both standard and customized sequencing library preparation. Collaborates on genomics, transcriptomics and epigenomics projects.

Proper citation: University of Montana Genomics Core Facility (RRID:SCR_028659) Copy   


https://bpdf.unl.edu/

Core is dedicated process development and through GMP production facility within the UNL College of Engineering, primary focus on microbial (bacteria, yeast) expression systems. Offers biopharmaceutical process development and biomanufacturing services that transition discoveries to non-clinical studies and Phase I/II and early Phase III clinical trials.

Proper citation: University of Nebraska Lincoln Biological Process Development Facility BPDF Core Facility (RRID:SCR_028634) Copy   


https://parisbraininstitute.org/paris-brain-institute-proteomics-core-facility

Core specializes in advanced analysis of proteins to investigate brain functions and neurological disorders. Provides equipment to study protein structure, interactions, and modifications. Services include Mass Spectrometry and Advanced Analysis, Protein Production and Engineering, Amplification of Misfolding Proteins, Highly Sensitive Multiplexed Immunodetection, Sample Preparation and Fractionation.

Proper citation: Paris Brain Institute Proteomics Core Facility (RRID:SCR_028641) Copy   


https://microscopy.duke.edu/

Core offers confocal and conventional fluorescence microscopes and image analysis resources. Provides access to standard and advanced imaging instrumentation. Imaging services include help with live cells, fixed samples, model organisms, small animals, single molecules or at most points in between.

Proper citation: Duke University Light Microscopy Core Facility (RRID:SCR_028637) Copy   


https://umc.edu/som/Departments%20and%20Offices/SOM%20Departments/Pharmacology%20and%20Toxicology/Research/Clinical-Research-Core.html

Facility promotes and facilitates faculty and student research in biomedical bench science. Provides supports for clinical research, expertise and resources to clinical and translational scientists and trainees. Offers services of clinical research coordinators and BSL2 facilities for the processing, storage or molecular experimentation of human biological samples. In addition, equipment and technical assistance for performing ELISAs, cell proliferation assays, autoantibody assays, nitric oxide (NO) measurements, reactive oxygen species (ROS) determination, proteomics, mitochondrial function, flow cytometry, Western immunoblotting, and cell cytokine secretion profiling are available.

Proper citation: University of Mississippi Medical Center Pharmacology Clinical Research Core Facility (RRID:SCR_028576) Copy   


https://www.crukscotlandinstitute.ac.uk/advanced-technologies/translational-molecular-imaging.html

Core provides expertise in radiochemistry, PET tracer development, preclinical PET and MRI imaging, cancer modelling, and advanced image analysis. Supports translational imaging research, with strengths in molecular imaging, pharmacodynamic biomarker development, and AI-enabled image analytics. Provided instruments include a GE PETtrace 800 cyclotron, radiosynthesis platforms, and small-animal NanoScan PET/MRI system. Services include expertise in both PET and MRI acquisition and analysis, supporting studies in cancer biology, metabolism, and therapy response.

Proper citation: Cancer Research UK Scotland Translational Molecular Imaging Group Core Facility (RRID:SCR_028697) Copy   


https://www.stemcell.columbia.edu/services/stem-cell-core

Multi-center facility at Columbia University Irving Medical Center, created to help users take advantage of up-to-date resources in the stem cell field in a timely and cost-efficient way. Offered services include giving access to quality-controlled pluripotent stem cells and stem cell-derivatives prepared using standardized approaches; genome editing services for the generation of custom-designed cell lines; training sessions and informal interactions between scientists from multiple laboratories working on different stem cell models. Some reagents commonly used in stem cell labs, as mTeSR1 media and irradiated mouse embryonic fibroblasts, are also available at discounted prices for our users. We are connected to Stem Cell COREdinates(link is external and opens in a new window), a consortium of pluripotent stem cell-focused core facilities, which allows us to take advantage of the sharing of the most updated and efficient protocols, expertise, and reagents.

Proper citation: Columbia University Stem Cell Core Facility (RRID:SCR_028575) Copy   


https://aimrc.uark.edu/imaging-and-spectroscopy-core/

Core is a fee-for-use COBRE core that houses multi-photon microscopes and light microscopes that allow high-resolution visualization of cell and tissue structure (mitochondrial networks, collagen structure), metabolic function (optical redox and NADH fluorescence lifetime measurements), and biomolecular composition (autofluorescent metabolic cofactors, lipid deposition).

Proper citation: University of Arkansas AIMRC Imaging and Spectroscopy Core Facility (RRID:SCR_028578) Copy   


https://nuklearmedizin.charite.de/forschung/praeklinische_forschung/

Core provides comprehensive preclinical imaging and radiochemistry services. Expertise covers the entire pipeline from study design to data analysis. Services include preclinical research (mice, rats, CAM assay, zebrafish, slugs) using radionuclide imaging via SPECT/CT and PET/CT, as well as 3T MRI, µCT, radiochemistry, tracer biokinetics, and kinetic modeling.

Proper citation: Charite Berlin University of Medicine Berlin Experimental Radionuclide Imaging Center BERIC Core Facility (RRID:SCR_028573) Copy   


https://institute-genetics-cancer.ed.ac.uk/mass-spectrometry

Core offers proteomics, metabolomics, and lipidomics services.Core specialises in working with precious and low-input samples including single-cell proteomics, deep visual proteomics from FFPE tissue, and integrated multiomics from a single sample. Every project is supported from experimental design through to full bioinformatic analysis and biological interpretation.Proteomics: from bulk expression to single-cell and spatial resolution. Metabolomics: precise identification and isotope tracing of metabolic pathways.Lipidomics: high-accuracy profiling of cellular lipid landscapes and signalling. Speciality: Spatial, Single-Cell and Integrated Multiomics: proteins, metabolites and lipids from the same precious sample.

Proper citation: University of Edinburgh Institute of Genetics and Cancer IGC Mass Spectrometry Core Facility (RRID:SCR_028620) Copy   



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