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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.cores.emory.edu/rbc/
One of the Emory Integrated Core Facilities (EICF), is supported by Emory University School of Medicine and the Georgia Clinical and Translational Science Alliance. We plan, execute, and analyze behavioral experiments examining activity, arousal, coordinated movement, learning and memory, anxiety, depression, seizure susceptibility, reward/reinforcement, and aggression in mice and rats.
Proper citation: Emory University Rodent Behavioral Core (RRID:SCR_012499) Copy
https://www.mri.psu.edu/materials-characterization-lab
Fully-staffed, open access, analytical research facility at Penn State's Materials Research Institute. Provided services include Surface Analysis (XPS, AFM, AES), Electron Microscopy (TEM, SEM, FIB, EPMA), X-ray Scattering (XRD and SAXS), Molecular Spectroscopy (FTIR, Raman, UV-VIs-NIR), Electrical Testing, Optical Microscopy, Thermal Analysis, Mechanical Testing, and Sample Preparation.
Proper citation: Pennsylvania State University Materials Characterization Lab Core Facility (RRID:SCR_012386) Copy
https://bcmb.franklin.uga.edu/bff
BFF consists of Fermentation Research Facility, Protein Purification Facility, Monoclonal Antibody Facility and Cell Culture Facility. Provides services covering wide range of biomanufacturing areas, protein expression, purification and antibody discovery.Provides equipment and expertise in biotechnological applications to academic and industry clients.
Proper citation: University of Georgia Bioexpression and Fermentation Core Facility (RRID:SCR_012421) Copy
https://www.unmc.edu/vcr/cores/vcr-cores/mspcf/index.html
MSPCF maintains and uses equipment for protein separation and imaging, as well as for sample preparation for mass spectrometry analysis. Offers range of bioinformatics tools for data mining and evaluation. Services include Protein Identification, Protein Interactome Analysis, Protein Post-translational Modifications, Quantitative Mass Spectrometry, Molecular Weight determination.
Proper citation: University of Nebraska Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_012539) Copy
https://cbc.arizona.edu/research/support-services/facilities/nuclear-magnetic-resonance-nmr
Interdisciplinary NMR spectroscopy research facility for structural elucidation and study of conformation and dynamics of organic compounds, peptides, oligonucleotides and other small biopolymers.
Proper citation: University of Arizona Nuclear Magnetic Resonance Core Facility (RRID:SCR_012716) Copy
http://www.uab.edu/shp/drc/animal-physiology-core-links
Core that provides diabetes researches with diabetes related phenotyping in small animal models. Their services offered include the assessment of body composition, energy balance, glucose homeostasis, cardiovascular assessment, imaging, and transgenic animals models.
Proper citation: University of Alabama at Birmingham Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015110) Copy
https://www.sbpdiscovery.org/biomedical-research/shared-resources/cancer-metabolism
Facility that aims to investigate role of metabolism in cancer on cellular and organismal level, combining in vitro and in vivo analysis. Comprehensive metabolic facility, including stable isotope tracing and flux analysis. Provides analysis of metabolism using specialist instruments and methodologies, together with advice on planning experiments and analyzing data. All instruments and approaches are available on fee-for-service basis to Cancer Center scientists, but alsoto outside users. Samples for most services can be shipped, but Seahorse analyzer users need to be local so they can bring live cells for analysis.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Cancer Metabolism Core Facility (RRID:SCR_014873) Copy
http://www.scripps.edu/florida/technologies/cbs/index.html
Core facility that provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes. Services include cell lines, hit-picking clones and various screening sets, and access to equipment.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.
Proper citation: Scripps Research Institute Florida Cell Based High Throughput Screening Core Facility (RRID:SCR_014877) Copy
https://sbpdiscovery.org/research/shared-resources/flow-cytometry/
Facility that provides access to high-speed cell sorting, analytical flow cytometry, imaging flow cytometry, and validated immune profiling spectral antibody panels. Core staff provide technical expertise in experiment design, data analysis, hardware and software training, operate the facility cell sorters, and are available to assist with analysis experiments for those who prefer to have their samples run by an expert cytometrist.
Proper citation: Sanford Burnham Prebys Medical Discovery Institute Flow Cytometry Core Facility (RRID:SCR_014854) Copy
https://nbcc.lunenfeld.ca/facilities/flow-cytometry
Core provides flow cytometry analyzers and cell sorters, with specialty in image-based flow cytometry and cell sorting.Services include unassisted and full-service cell sorting, training on theory and on instruments, consultation on experiment design, protocol development, data analysis, manuscript preparation and grant submission. Applications include image-based analysis powered by machine learning on the Amnis ImageStream; image-based cell sorting using the BD BACS Discover S8; cell sorting for a variety of applications including multi-color sort for bulk culture, indexed cell sort into 96-well plates, cell cycle phase sort and primary tissue sorting for RNA or DNA analysis.
Proper citation: Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre Flow Cytometry Core Facility (RRID:SCR_025384) Copy
https://nbcc.lunenfeld.ca/facilities/next-gen-sequencing
Core provides both short and long read sequencing capabilities for analysis of gene function and expression.Facility specializes in functional genomics and single cell biology. Services include consultation, sample preparation (especially for spatial and single cell applications), quality control, sequencing analysis, bioinformatics support, and assistance with grant and publication writing related to the services. Applications include:gene function analysis - pooled CRISPR screening, multiplexed barcode screens; whole genome sequencing - both short- and long-read sequencing; bulk gene expression profiling; single cell biology (single cells and single nuclei); spatial profiling; pathogen detection and profiling.
Proper citation: Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre Next-Generation Sequencing Core Facility (RRID:SCR_025385) Copy
https://sites.dartmouth.edu/cqb/projects-and-cores/data-analytics-core/
Core offers statistical analysis of genomics data. Provides suite of standardized analysis pipelines for common data types like RNA-seq, ATAC-seq, and genome assembly. For more complex datasets, such as single-cell genomics, provides tailored analysis solutions. Core team assists with all project stages, from experimental design to publication support and data management. GDSC hosts several multi-day bioinformatics workshops designed to introduce fundamental concepts for analysis of genomics data.
Proper citation: Dartmouth Genomic Data Sciences Core Facility (RRID:SCR_025383) Copy
https://nbcc.lunenfeld.ca/facilities/high-throughput-screening
Provides instrumentation and expertise for the automation of laboratory processes. Facility has automated screening platforms and accessory equipment to enable flexible and scalable in vitro and in vivo assays including organoids. Services include access to chemical and genome-wide siRNA libraries, assay development and implementation, and data analysis. Applications include drug discovery and lead validation; ELISA-based assays for immune surveillance; protein biomarker discovery using OLINK proteomics technology; multiplexed barcode screening assays.
Proper citation: Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre High-Throughput Screening Core Facility (RRID:SCR_025390) Copy
https://hillmanresearch.upmc.edu/research/shared-resources/cellular-therapies
Hillman/University of Pittsburgh co-managed ACCT Labs are cell therapy labs located in more than 15,000 sq ft of lab space, boasting 12 clean rooms. ACCT labs offer services and expertise including the manufacturing cell therapy products for cancer cell therapy trials. The labs are also responsible for monitoring immune function through cell therapy treatments and processing blood products for a number of clinical trials.
Proper citation: University of Pittsburgh Hillman Cancer Center Advanced Cancer Cellular Therapy (ACCT) Laboratory Core Facility (RRID:SCR_025362) Copy
https://hillmanresearch.upmc.edu/research/facilities/in-vivo-imaging/
Provides novel quantitative imaging techniques that trace biomarkers of molecular events associated with effective cancer therapy.
Proper citation: University of Pittsburgh Hillman Cancer Center In Vivo Imaging Core Facility (RRID:SCR_025360) Copy
https://bioinformatics.sph.harvard.edu/
Provides single point of contact for Harvard researchers interested in bioinformatics support, applying genomic approaches together with established and developing methodologies from epidemiology, environmental health, biostatistics and bioinformatics to improve human health.Services include analysis all types of next-generation sequencing data from RNA-seq and single cell RNA-seq to variant sequencing (exome or whole genome), to ChIP-seq or bisulfite sequencing. Offers bioinformatics training program for Harvard researchers interested in learning basic data skills and analysis of high-throughput sequencing data.
Proper citation: Harvard University Chan School of Public Health Bioinformatics Core Facility (RRID:SCR_025373) Copy
https://mriresearch.med.ubc.ca/
Facility consist of Philips 3.0 Tesla MRI scanner for studies on humans, Bruker small bore 9.4 Tesla MRI scanner, and computing facility for image archival and analysis. Scanners are entirely dedicated to research, and MR scanning is carried out on cost recovery basis. The scanners were selected to cater to a very broad range of in vivo applications and the Imaging Centre staff is trained to support any research projects that the scanners can accommodate.
Proper citation: University of British Columbia MRI Research Core Facility (RRID:SCR_025374) Copy
https://www.ncl.ac.uk/bioimaging/
Light microscopy core facility at Newcastle University based in the Faculty of Medical Sciences, providing services, access, training and support for light microscopy.
Proper citation: Newcastle University Bioimaging Unit Core Facility (RRID:SCR_025354) Copy
https://hillmanresearch.upmc.edu/research/facilities/biostatistics/
Provides statistical and computational methods for design, execution, analysis, and reporting of cancer-related research studies and trials including biomarker analysis and grant development.
Proper citation: University of Pittsburgh Hillman Cancer Center Biostatistics Core Facility (RRID:SCR_025355) Copy
https://hillmanresearch.upmc.edu/research/facilities/cancer-genomics/
Supports genomics and transcriptomics platforms including nucleic acid extraction, sample QC, next-generation library preparation and sequencing. Specializes in paraffin-embedded tissue samples.
Proper citation: University of Pittsburgh Hillman Cancer Center Cancer Genomics Core Facility (RRID:SCR_025357) Copy
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