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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
aCGHtool
 
Resource Report
Resource Website
1+ mentions
aCGHtool (RRID:SCR_010915) aCGHtool software resource A software tool for the normalization, visualization, breakpoint detection, and comparative analysis of array-CGH data which allows the accurate and sensitive detection of CNAs. is listed by: OMICtools OMICS_00699 SCR_010915 2026-08-01 12:04:18 1
Agilent Genomic Workbench
 
Resource Report
Resource Website
100+ mentions
Agilent Genomic Workbench (RRID:SCR_010918) Agilent Genomic Workbench software resource A comprehensive design and analysis tool for setting up and interpreting your microarray experiments. is listed by: OMICtools OMICS_00702 SCR_010918 2026-08-01 12:04:18 248
DBChIP
 
Resource Report
Resource Website
1+ mentions
DBChIP (RRID:SCR_010872) DBChIP software resource Detects differential binding of transcription factors with ChIP-seq. is listed by: OMICtools OMICS_00470 SCR_010872 2026-08-01 12:03:59 5
DIME
 
Resource Report
Resource Website
10+ mentions
DIME (RRID:SCR_010874) DIME software resource R-package for identifying differential ChIP-seq based on an ensemble of mixture models. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
biotools:DIME, OMICS_00473 https://bio.tools/DIME SCR_010874 2026-08-01 12:04:18 29
ChIPModule
 
Resource Report
Resource Website
1+ mentions
ChIPModule (RRID:SCR_010877) ChIPModule software resource A software tool for systematic discovery of transcription factors and their cofactors from ChIP-seq data. is listed by: OMICtools OMICS_00477 SCR_010877 ChIPModule: Systematic discovery of transcription factors and their cofactors from ChIP-seq data 2026-08-01 12:04:18 1
CloudBurst
 
Resource Report
Resource Website
CloudBurst (RRID:SCR_010911) CloudBurst software resource A new parallel read-mapping algorithm optimized for mapping next-generation sequence data to the human genome and other reference genomes, for use in a variety of biological analyses including SNP discovery, genotyping, and personal genomics. mapreduce/hadoop, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:19357099 Free OMICS_00657, biotools:cloudburst https://bio.tools/cloudburst SCR_010911 2026-08-01 12:04:00 0
ERNE
 
Resource Report
Resource Website
10+ mentions
ERNE (RRID:SCR_010912) ERNE software resource A short string alignment package whose goal is to provide an all-inclusive set of tools to handle short (NGS-like) reads. is listed by: OMICtools
has parent organization: SourceForge
OMICS_00662 SCR_010912 2026-08-01 12:04:18 46
F-Seq
 
Resource Report
Resource Website
50+ mentions
F-Seq (RRID:SCR_010880) F-Seq software resource A software package that generates a continuous tag sequence density estimation allowing identification of biologically meaningful sites whose output can be displayed directly in the UCSC Genome Browser. is listed by: OMICtools
has parent organization: University of North Carolina at Chapel Hill; North Carolina; USA
OMICS_00482 SCR_010880 2026-08-01 12:04:17 83
ABySS-Explorer
 
Resource Report
Resource Website
1+ mentions
ABySS-Explorer (RRID:SCR_010980) ABySS-Explorer software resource An interactive Java application that employs a novel graph-based representation to display a sequence assembly and associated meta data. is listed by: OMICtools OMICS_00873 SCR_010980 2026-08-01 12:04:18 3
DNPTrapper
 
Resource Report
Resource Website
DNPTrapper (RRID:SCR_010981) DNPTrapper software resource An assembly editing and visualization tool specifically designed for manual analysis and finishing of repeated regions. c++ is listed by: OMICtools
has parent organization: SourceForge
PMID:16549006 OMICS_00881 SCR_010981 2026-08-01 12:04:19 0
Hawkeye
 
Resource Report
Resource Website
1+ mentions
Hawkeye (RRID:SCR_010982) Hawkeye software resource A visual analytics tool for genome assembly analysis and validation, designed to aid in identifying and correcting assembly errors. is listed by: OMICtools
has parent organization: SourceForge
OMICS_00884 SCR_010982 2026-08-01 12:04:19 9
VariationHunter
 
Resource Report
Resource Website
10+ mentions
VariationHunter (RRID:SCR_004865) VariationHunter software resource A software tool for discovery of structural variation in one or more individuals simultaneously using high throughput technologies. structural variation, genome, next-generation sequencing is listed by: OMICtools
is related to: SPLITREAD
has parent organization: Simon Fraser University; British Columbia; Canada
has parent organization: SourceForge
PMID:22048523
PMID:20529927
OMICS_00328 SCR_004865 VariationHunter-CommonLaw 2026-08-01 12:02:48 12
Phymm and PhymmBL
 
Resource Report
Resource Website
10+ mentions
Phymm and PhymmBL (RRID:SCR_004751) Phymm, PhymmBL software resource Software for Phylogenetic Classification of Metagenomic Data with Interpolated Markov Models to taxonomically classify DNA sequences and accurately classify reads as short as 100 bp. PhymmBL, the hybrid classifier included in this distribution which combines analysis from both Phymm and BLAST, produces even higher accuracy. metagenome, sequence, taxonomy, classification, phylogenetic classification, genome, short read is listed by: OMICtools
has parent organization: University of Maryland; Maryland; USA
NLM R01-LM006845 PMID:19648916
PMID:21527926
Open-source license OMICS_01461 SCR_004751 2026-08-01 12:02:44 12
deStruct
 
Resource Report
Resource Website
1+ mentions
deStruct (RRID:SCR_004747) deStruct software resource A software tool for identifying structural variation in tumour genomes from whole genome illumina sequencing. structural variation, genome, genomics is listed by: OMICtools
has parent organization: Google Code
Tumor, Cancer Open unspecified license OMICS_00314 SCR_004747 deStruct - Bioinformatics tool for identifying structural variation in tumour genomes 2026-08-01 12:02:44 7
SLIQ
 
Resource Report
Resource Website
1+ mentions
SLIQ (RRID:SCR_005003) SLIQ software resource Software for simple linear inequalities based Mate-Pair reads filtering and scaffolding. A set of simple linear inequalities (SLIQ) derived from the geometry of contigs on the line that can be used to predict the relative positions and orientations of contigs from individual mate pair reads and thus produce a contig digraph. The SLIQ inequalities can also filter out unreliable mate pairs and can be used as a pre-processing step for any scaffolding algorithm. This tool filters mate pairs and then produces a Directed Contig Graph (contig diGraph). Also provided is a Naive scaffolder that can then produce scaffolds out of the contig diGraph. python, scaffolding, contig position, contig orientation, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:23057825 biotools:sliq, OMICS_00048 https://bio.tools/sliq SCR_005003 Simple linear inequalities, SLiQ: Simple linear inequalities based Mate-Pair reads filtering and scaffolding 2026-08-01 12:02:51 3
cortex var
 
Resource Report
Resource Website
1+ mentions
cortex var (RRID:SCR_005081) cortex_var software resource A tool for genome assembly and variation analysis from sequence data. You can use it to discover and genotype variants on single or multiple haploid or diploid samples. If you have multiple samples, you can use Cortex to look specifically for variants that distinguish one set of samples (eg phenotype=X, cases, parents, tumour) from another set of samples (eg phenotype=Y, controls, child, normal). cortex_var features * Variant discovery by de novo assembly - no reference genome required * Supports multicoloured de Bruijn graphs - have multiple samples loaded into the same graph in different colours, and find variants that distinguish them. * Capable of calling SNPs, indels, inversions, complex variants, small haplotypes * Extremely accurate variant calling - see our paper for base-pair-resolution validation of entire alleles (rather than just breakpoints) of SNPs, indels and complex variants by comparison with fully sequenced (and finished) fosmids - a level of validation beyond that demanded of any other variant caller we are aware of - currently cortex_var is the most accurate variant caller for indels and complex variants. * Capable of aligning a reference genome to a graph and using that to call variants * Support for comparing cases/controls or phenotyped strains * Typical memory use: 1 high coverage human in under 80Gb of RAM, 1000 yeasts in under 64Gb RAM, 10 humans in under 256 Gb RAM genome assembly, variation analysis, sequence, variation, genotype variant, haploid, diploid, snp, indel, inversion, variant, haplotype, de novo assembly, genotyping, variant-calling, population analysis, population assembly is listed by: OMICtools
has parent organization: SourceForge
has parent organization: Wellcome Trust Centre for Human Genetics
PMID:22231483 GNU General Public License, v3, Acknowledgement requested OMICS_00056 SCR_005081 cortex_var - for variant and population assembly 2026-08-01 12:02:54 3
SOPRA
 
Resource Report
Resource Website
10+ mentions
SOPRA (RRID:SCR_005035) SOPRA software resource Software tool to exploit the mate pair/paired-end information for assembly of short reads from high throughput sequencing platforms, e.g. Illumina and SOLiD. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Rutgers University; New Jersey; USA
PMID:20576136 Acknowledgement requested biotools:sopra, OMICS_00049 https://bio.tools/sopra SCR_005035 SOPRA - Statistical Optimization of Paired Read Assembly, Statistical Optimization of Paired Read Assembly 2026-08-01 12:02:48 20
SSPACE
 
Resource Report
Resource Website
100+ mentions
SSPACE (RRID:SCR_005056) SSPACE software resource A stand-alone software program for scaffolding pre-assembled contigs using paired-read data. Main features are: a short runtime, multiple library input of paired-end and/or mate pair datasets and possible contig extension with unmapped sequence reads. scaffolding, contig, genome, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:21149342
DOI:10.1093/bioinformatics/btq683
GNU General Public License, Registration required biotools:sspace, OMICS_00050 https://bio.tools/sspace, https://sources.debian.org/src/sspace/ SCR_005056 2026-08-01 12:02:53 426
HPC-CLUST
 
Resource Report
Resource Website
1+ mentions
HPC-CLUST (RRID:SCR_005052) HPC-CLUST software resource A set of tools designed to cluster large numbers (>1 million) of pre-aligned nucleotide sequences. It performs the clustering of sequences using the Hierarchical Clustering Algorithm (HCA). There are currently three different cluster metrics implemented: single-linkage, complete-linkage, and average-linkage. In addition, there are currently four sequence distance functions implemented, these are: identity (gap-gap counting as match), nogap (gap-gap being ignored), nogap-single (like nogap, but consecutive gap-nogap''s count as a single mismatch), tamura (distance is calculated with the knowledge that transitions are more likely than transversions). One advantage that HCA has over other algorithms is that instead of producing only the clustering at a given threshold, it produces the set of merges occuring at each threshold. With this approach, the clusters can afterwards very quickly be reported for every arbitrary threshold with little extra computation. This approach also allows the plotting of the variation of number of clusters with clustering threshold without requiring the clustering to be run for each threshold independently. Another feature of the way HPC-CLUST is implemented is that the single-, complete-, and average-linkage clusterings can be computed in a single run with little overhead. c++, mpi is listed by: OMICtools
has parent organization: University of Zurich; Zurich; Switzerland
PMID:24215029 OMICS_01446 SCR_005052 2026-08-01 12:02:48 5
M-pick
 
Resource Report
Resource Website
M-pick (RRID:SCR_004995) M-pick software resource A modularity-based clustering software for Operational Taxonomic Unit (OTU) picking of 16S rRNA sequences. The algorithm does not require a predetermined cut-off level, and our simulation studies suggest that it is superior to existing methods that require specified distance or variance levels to define OTUs. 16s rrna sequence, 16s rrna, rrna, sequence, binning is listed by: OMICtools
has parent organization: University of Florida; Florida; USA
OMICS_01447 SCR_004995 M-pick: a modularity-based clustering method for OTU picking 2026-08-01 12:02:51 0

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