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https://www.crukscotlandinstitute.ac.uk/advanced-technologies/deep-phenotyping.html

Core offers comprehensive pathologist-led spatial biology service comprising spatial proteomic, transcriptomic, and multiomic experimental design, including platform and panel selection, assay development, image acquisition, and digital image processing. The facility houses 2x Ventana Discovery Ultra autostainers, 2x 10 x Genomics Xenium platforms, a Lunaphore COMET, an Akoya PhenoImager, an Akoya PhenoCycler, an Olympus VS200 slide scanner and a Visiopharm image analysis suite.

Proper citation: CRUK Scotland Institute Deep Phenotyping Advanced Technology Core Facility (RRID:SCR_027366) Copy   

•   Source: SciCrunch Registry

https://www.crukscotlandinstitute.ac.uk/advanced-technologies/molecular-technology.html

Core provides Next Generation Sequencing (NGS) services and Single Cell services predominantly focussing on single cell RNAseq. Processes samples for variety of cancer associated projects, in both mouse and human derived materials. Offers full end-to-end service, from initial study design and planning, through sample QC, full library preparation, sequencing and data return. Offers range of standard molecular tests covering, plasmid purifications, Sanger sequencing and mycoplasma screening.

Proper citation: Cancer Research UK Scotland Institute Molecular Technology Service Core Facility (RRID:SCR_027368) Copy   

•   Source: SciCrunch Registry

https://www.lsuhs.edu/centers/cardiovascular-diseases-and-sciences/research-resources/core-facilities

Core provides centralized service for performing technically challenging mouse models of cardiovascular disease, such as middle cerebral artery occlusion (MCAO) stroke model, coronary artery ligation model of myocardial ischemia, femoral artery ligation model of peripheral artery disease, and partial carotid artery ligation model of disturbed blood flow.

Proper citation: Louisiana State University in Shreveport Center for Cardiovascular Diseases and Sciences (CCDS) Surgical Models Core Facility (RRID:SCR_027497) Copy   

•   Source: SciCrunch Registry

https://www.lsuhs.edu/centers/cardiovascular-diseases-and-sciences/research-resources/core-facilities

Core provides centralized service for generating AAV particles for cardiovascular studies. The CCDS Virus Production Core offers the production of either pre-made (ex. AAV8-GFP, AAV8 mPCSK9 D377Y) or custom AAVs.

Proper citation: Louisiana State University in Shreveport Center for Cardiovascular Diseases and Sciences (CCDS) Virus Production Core Facility (RRID:SCR_027498) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/cancer/research/shared-resources/bioinformatics/

Georgia Cancer Center's Bioinformatics Core provides expertise in integrative computational based analysis solutions to basic, clinical, and translational research applications. Services include study design, analysis, and interpretation that may involve interaction with industry, government, and regulatory agencies in the areas of Clinical trials, Epidemiology, laboratory studies, in addition to data mining using local and national databases for hypotheses generation and scientific investigation.

Proper citation: Augusta University Bioinformatics Shared Resource Core Facility (RRID:SCR_027372) Copy   

•   Source: SciCrunch Registry

https://www.med.uvm.edu/bsr/home

Core offers bioinformatics and data modeling services. Focuses on support for reproducible, well documented, containerized, nextflow pipelines customized to address the specific research questions and biological systems of the investigators. Offers support from preprocessing -omics data, through data integration and manuscript support, based on grant support or a fee-for-service mechanism. Provides training for students and PIs in the form of individual help, seminars, and workshops.

Proper citation: University of Vermont Bioinformatics Shared Resource Core Facility (RRID:SCR_027493) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/light-microscopy/

Core services include: basic light microscopy (determine appropriate staining protocols and offer training and/or assistance in acquiring transmitted and fluorescent digital images with wide-field microscopes); optical sectioning (training and assistance in the use of confocal and multi-photon microscopes); whole slide scanning (brightfield or fluorescence mode). Laser MicroDissection instruments are available for isolating small areas of tissue or single cells. Total Interference Reflection Fluorescence (TIRF) microscopy is available for visualizing and quantifying cellular events localized at the basal plasma membrane. Live cell and tissue imaging can be done on both wide-field and confocal microscopes equipped with environmental chambers for heat/CO2 control.Investigators have access to Image Processing and Analysis workstations with variety of advanced software for extracting quantitative data from their images. They can also generate images and movies for presentations, grants and publications. Core is home to 2 LI-COR Odyssey, laser-based scanning systems for gels, Westerns, in-cell Westerns, ELISA/FLISA, EMSA/Gel Shift, Protein Detection, etc.

Proper citation: Cleveland Clinic Lerner Research Institute Light Microscopy Core Facility (RRID:SCR_027477) Copy   

•   Source: SciCrunch Registry

https://www.houstonmethodist.org/academic-institute/research/cores/

Core is fee-for-service research laboratory providing internal and external users a wide spectrum of electron microscopy (EM) techniques. As part of the Houston Methodist Research Institute Department of Neurology, we routinely process samples related to the peripheral nervous system but can help with the ultrastructural study of many biological samples.

Proper citation: Houston Methodist HMRI Neurology Electron Microscopy Core Facility (RRID:SCR_027479) Copy   

•   Source: SciCrunch Registry

https://rcgd.isr.umich.edu/research/facilities/zajonc-lab/

Core provides researchers with facilities to conduct experimental research, particularly within the Research Center for Group Dynamics (RCGD) and across the U-M campus. The labs offer adaptable room configurations, specialized software like E-Prime and z-Tree, and shared access to cutting-edge technology, including a new Virtual Reality (VR) Lab, to support a range of interdisciplinary research projects focused on human social behavior and dynamics.

Proper citation: University of Michigan Robert B. Zajonc Experimental Lab Core Facility (RRID:SCR_027478) Copy   

•   Source: SciCrunch Registry

https://chem.vt.edu/analyticalservices/surface-analysis-lab.html

Core offers contemporary surface analysis techniques, featuring the latest PHI VersaProbe III Scanning XPS Microscope, and expertise.

Proper citation: Virginia Tech VT Surface Analysis Laboratory Core Facility (RRID:SCR_027504) Copy   

•   Source: SciCrunch Registry

https://moffitt.org/research-science/shared-resources/molecular-genomics/

Molecular Genomics Core Facility at Moffitt Cancer Center in Tampa, FL offers services to assess gene expression, epigenetic modification and sequence variation. Performs bulk and single cell RNA and DNA sequencing on Illumina platform, NanoString nCounter, GeneChip and Illumina array services.Offers services to discuss your project and timeline for your project.

Proper citation: Moffitt Cancer Center Molecular Genomics Core Facility (RRID:SCR_012333) Copy   

•   Source: SciCrunch Registry

https://www.cores.emory.edu/rbc/

One of the Emory Integrated Core Facilities (EICF), is supported by Emory University School of Medicine and the Georgia Clinical and Translational Science Alliance. We plan, execute, and analyze behavioral experiments examining activity, arousal, coordinated movement, learning and memory, anxiety, depression, seizure susceptibility, reward/reinforcement, and aggression in mice and rats.

Proper citation: Emory University Rodent Behavioral Core (RRID:SCR_012499) Copy   

•   Source: SciCrunch Registry

https://www.mri.psu.edu/materials-characterization-lab

Fully-staffed, open access, analytical research facility at Penn State's Materials Research Institute. Provided services include Surface Analysis (XPS, AFM, AES), Electron Microscopy (TEM, SEM, FIB, EPMA), X-ray Scattering (XRD and SAXS), Molecular Spectroscopy (FTIR, Raman, UV-VIs-NIR), Electrical Testing, Optical Microscopy, Thermal Analysis, Mechanical Testing, and Sample Preparation.

Proper citation: Pennsylvania State University Materials Characterization Lab Core Facility (RRID:SCR_012386) Copy   

•   Source: SciCrunch Registry

https://bcmb.franklin.uga.edu/bff

BFF consists of Fermentation Research Facility, Protein Purification Facility, Monoclonal Antibody Facility and Cell Culture Facility. Provides services covering wide range of biomanufacturing areas, protein expression, purification and antibody discovery.Provides equipment and expertise in biotechnological applications to academic and industry clients.

Proper citation: University of Georgia Bioexpression and Fermentation Core Facility (RRID:SCR_012421) Copy   

•   Source: SciCrunch Registry

https://cbc.arizona.edu/research/support-services/facilities/nuclear-magnetic-resonance-nmr

Interdisciplinary NMR spectroscopy research facility for structural elucidation and study of conformation and dynamics of organic compounds, peptides, oligonucleotides and other small biopolymers.

Proper citation: University of Arizona Nuclear Magnetic Resonance Core Facility (RRID:SCR_012716) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/mspcf/index.html

MSPCF maintains and uses equipment for protein separation and imaging, as well as for sample preparation for mass spectrometry analysis. Offers range of bioinformatics tools for data mining and evaluation. Services include Protein Identification, Protein Interactome Analysis, Protein Post-translational Modifications, Quantitative Mass Spectrometry, Molecular Weight determination.

Proper citation: University of Nebraska Medical Center Mass Spectrometry and Proteomics Core Facility (RRID:SCR_012539) Copy   

•   Source: SciCrunch Registry

https://www.sbpdiscovery.org/biomedical-research/shared-resources/cancer-metabolism

Facility that aims to investigate role of metabolism in cancer on cellular and organismal level, combining in vitro and in vivo analysis. Comprehensive metabolic facility, including stable isotope tracing and flux analysis. Provides analysis of metabolism using specialist instruments and methodologies, together with advice on planning experiments and analyzing data. All instruments and approaches are available on fee-for-service basis to Cancer Center scientists, but alsoto outside users. Samples for most services can be shipped, but Seahorse analyzer users need to be local so they can bring live cells for analysis.

Proper citation: Sanford Burnham Prebys Medical Discovery Institute Cancer Metabolism Core Facility (RRID:SCR_014873) Copy   

•   Source: SciCrunch Registry

http://www.scripps.edu/florida/technologies/cbs/index.html

Core facility that provides access to genome-wide collections of cDNAs and siRNAs that can be used to interrogate cellular models of signal transduction pathways and phenotypes. Services include cell lines, hit-picking clones and various screening sets, and access to equipment.Provides instruments:Analyst Molecular Devices,Embla Molecular Devices, Envision Perkin Elmer, Platemate Matrix, Tecan M200, Wellmate Matrix.

Proper citation: Scripps Research Institute Florida Cell Based High Throughput Screening Core Facility (RRID:SCR_014877) Copy   

•   Source: SciCrunch Registry

https://sbpdiscovery.org/research/shared-resources/flow-cytometry/

Facility that provides access to high-speed cell sorting and analytical flow cytometry. Core allows investigators to have 24-hr/day access to variety of analytical flow cytometers available for independent use. Core staff provide technical expertise and hardware and software training, operate the facility cell sorters, and are available to assist with analysis experiments for those who prefer to have their samples run by an expert cytometrist.

Proper citation: Sanford Burnham Prebys Medical Discovery Institute Flow Cytometry Core Facility (RRID:SCR_014854) Copy   

•   Source: SciCrunch Registry

http://www.uab.edu/shp/drc/animal-physiology-core-links

Core that provides diabetes researches with diabetes related phenotyping in small animal models. Their services offered include the assessment of body composition, energy balance, glucose homeostasis, cardiovascular assessment, imaging, and transgenic animals models.

Proper citation: University of Alabama at Birmingham Diabetes Research Center Animal Physiology Core Facility (RRID:SCR_015110) Copy   

•   Source: SciCrunch Registry