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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
BIGpre
 
Resource Report
Resource Website
BIGpre (RRID:SCR_006781) BIGpre software resource A quality assessment software package for next-genomics sequencing data. next generation sequencing, genomics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:22289480 GNU General Public License, v3 biotools:bigpre, OMICS_01035 https://bio.tools/bigpre SCR_006781 2026-08-01 12:03:13 0
seqbias
 
Resource Report
Resource Website
10+ mentions
seqbias (RRID:SCR_006832) seqbias software resource Software package that implements a model of per-position sequencing bias in high-throughput sequencing data using a simple Bayesian network, the structure and parameters of which are trained on a set of aligned reads and a reference genome sequence. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
GNU Lesser General Public License OMICS_01237, biotools:seqbias, BioTools:seqbias https://bio.tools/seqbias, https://bio.tools/seqbias, https://bio.tools/seqbias SCR_006832 seqbias - Estimation of per-position bias in high-throughput sequencing data 2026-08-01 12:03:13 30
eDMR
 
Resource Report
Resource Website
10+ mentions
eDMR (RRID:SCR_006960) eDMR software resource Comprehensive differentially methylated regions (DMR) analysis based on bimodal normal distribution model and weighted cost function for regional methylation analysis optimization. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
MIT License biotools:edmr, OMICS_00622 https://bio.tools/edmr SCR_006960 2026-08-01 12:03:25 19
MethylAid
 
Resource Report
Resource Website
50+ mentions
MethylAid (RRID:SCR_002659) software resource Software for visual and interactive quality control of large Illumina 450k data sets. Bad quality samples are detected using sample-dependent and sample-independent controls present on the array and user adjustable thresholds. In depth exploration of bad quality samples can be performed using several interactive diagnostic plots of the quality control probes present on the array. Furthermore, the impact of any batch effect provided by the user can be explored. software package, illumina, mac os x, unix/linux, windows, r, dna methylation, gui, methylation array, microarray, quality control, two channel, visualization, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:25147358 Free, Available for download, Freely available biotools:methylaid, OMICS_05457 http://www.bioconductor.org/packages/release/bioc/html/MethylAid.html, http://shiny.bioexp.nl/MethylAid/, https://bio.tools/methylaid SCR_002659 MethylAid - Visual and interactive quality control of large Illumina 450k data sets, MethylAid: Visual and interactive quality control of large Illumina 450k data sets 2026-08-01 12:01:52 65
libmgf
 
Resource Report
Resource Website
libmgf (RRID:SCR_002664) software resource A flex/bison-based C++ Mascot Generic Format (MGF) parser library. standalone software, c++, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:20334363 Free, Available for download, Freely available OMICS_03343, biotools:libmgf, BioTools:libmgf https://bio.tools/libmgf, https://bio.tools/libmgf, https://bio.tools/libmgf SCR_002664 MGFp, libmgf (formerly MGFp) 2026-08-01 12:02:12 0
ExomeDepth
 
Resource Report
Resource Website
100+ mentions
ExomeDepth (RRID:SCR_002663) software resource Software that calls copy number variants (CNVs) from targeted sequence data, typically exome sequencing experiments designed to identify the genetic basis of Mendelian disorders. software package, unix/linux, mac os x, windows, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: CRAN
PMID:22942019 Free, Available for download, Freely available OMICS_05443, biotools:exomedepth https://bio.tools/exomedepth SCR_002663 2026-08-01 12:01:52 262
libCSAM
 
Resource Report
Resource Website
1+ mentions
libCSAM (RRID:SCR_002766) software resource Contains several C++ codes for compress, decompress, and access each of the fields of any SAM format file. standalone software, c++, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:24728856 Free, Freely available, Available for download OMICS_03750, biotools:libcsam https://bio.tools/libcsam SCR_002766 2026-08-01 12:02:16 1
RopeBWT2
 
Resource Report
Resource Website
10+ mentions
RopeBWT2 (RRID:SCR_002673) software resource A software tool for constructing the FM-index for a collection of DNA sequences. It works by incrementally inserting one or multiple sequences into an existing pseudo-BWT position by position, starting from the end of the sequences. This algorithm can be largely considered a mixture of BCR and dynamic FM-index. Nonetheless, ropeBWT2 is unique in that it may implicitly sort the input into reverse lexicographical order (RLO) or reverse-complement lexicographical order (RCLO) while building the index. standalone software, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: Burrows-Wheeler transform
PMID:25107872 Free, Available for download, Freely available biotools:ropebwt2, OMICS_05300 https://bio.tools/ropebwt2 SCR_002673 2026-08-01 12:02:13 11
NetPathMiner
 
Resource Report
Resource Website
1+ mentions
NetPathMiner (RRID:SCR_002757) software resource Software that implements a flexible module-based process flow for network path mining and visualization, which can be fully inte-grated with user-customized functions. It supports construction of various types of genome scale networks from three different pathway file formats (KGML, SBML and BioPAX), enabling its utility to most common pathway databases. In addition, it provides different visualization techniques to facilitate the analysis of even thousands of output paths. software package, mac os x, unix/linux, windows, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:25075120 Free, Freely available, Available for download biotools:netpathminer, OMICS_05210 https://bio.tools/netpathminer SCR_002757 NetPathMiner: R package for network path mining through gene expression 2026-08-01 12:01:54 3
GATE
 
Resource Report
Resource Website
100+ mentions
GATE (RRID:SCR_002756) data analysis resource Model-based, open source software analysis tool for chromatin states prediction based on time-course epigenetic marks data. It uses a combinatory Finite Mixture model nested with HMM to model the time course marks data in which each single hidden markov model describes the hidden states for a region set across different time points. chromatin state prediction software, time course epigenetic data, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:23033340 Free, Freely available, Available for download OMICS_03065, biotools:gate https://github.com/yu68/GATE, https://bio.tools/gate SCR_002756 Genomic Annotation from Time-couse Epigenomic data, Genomic Annotation from Time-couse Epigenomic data (GATE) 2026-08-01 12:02:16 317
pNovo+
 
Resource Report
Resource Website
1+ mentions
pNovo+ (RRID:SCR_002860) software resource A de novo peptide sequencing algorithm using complementary higher-energy collisional dissociation (HCD) and electron transfer dissociation (ETD) tandem mass spectra. mass spectrometry, proteomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Chinese Academy of Sciences; Beijing; China
PMID:23272783 Free, Freely available biotools.pNovo_3, OMICS_02470 https://bio.tools/pNovo_3 SCR_002860 2026-08-01 12:01:57 7
pairheatmap
 
Resource Report
Resource Website
pairheatmap (RRID:SCR_003109) software resource A software tool to compare two heatmaps and discover patterns within and across groups. In the context of biology, group can be defined based on gene ontology. standalone software, r, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: CRAN
PMID:24016862 Free, Available for download, Freely available biotools:pairheatmap, OMICS_04853 https://www.rdocumentation.org/packages/pairheatmap/versions/1.0.1/topics/pairheatmap SCR_003109 pairheatmap: A tool for comparing heatmaps 2026-08-01 12:02:02 0
MFEprimer
 
Resource Report
Resource Website
10+ mentions
MFEprimer (RRID:SCR_003066) software resource A fast thermodynamics-based software program for checking PCR primer specificity against genomic DNA and mRNA/cDNA sequence databases. standalone software, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22689644 Free, Available for download, Freely available biotools:mfeprimer-2.0, OMICS_02355 https://www.mfeprimer.com/ SCR_003066 MFEprimer-2.0 2026-08-01 12:02:01 19
eQtlBma
 
Resource Report
Resource Website
1+ mentions
eQtlBma (RRID:SCR_003102) software resource Software package that implements Bayesian statistical methods to detect eQTLs jointly in multiple subgroups (e.g. tissues). Key features are to borrow information across subgroups, to explicitly model heterogeneity (qualitatively and quantitatively), and to borrow information across genes to estimate hyper-parameters from the data (empirical Bayes). standalone software, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Chicago; Illinois; USA
PMID:23671422 Free, Available for download, Freely available biotools:eqtlbma, OMICS_04875 https://bio.tools/eqtlbma SCR_003102 2026-08-01 12:02:26 5
Triplex
 
Resource Report
Resource Website
10+ mentions
Triplex (RRID:SCR_003061) software resource Software package that provides functions for identification and visualization of potential intramolecular triplex patterns in DNA sequence. The main functionality is to detect the positions of subsequences capable of folding into an intramolecular triplex (H-DNA) in a much larger sequence. The potential H-DNA (triplexes) should be made of as many canonical nucleotide triplets as possible. The package includes visualization showing the exact base-pairing in 1D, 2D or 3D. software package, mac os x, unix/linux, windows, r, gene regulation, sequence matching, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Bioconductor
PMID:23709494 Free, Available for download, Freely available OMICS_06259, biotools:triplex http://www.fi.muni.cz/~lexa/triplex/, https://bio.tools/triplex SCR_003061 triplex - Search and visualize intramolecular triplex-forming sequences in DNA 2026-08-01 12:02:25 10
bwtool
 
Resource Report
Resource Website
10+ mentions
bwtool (RRID:SCR_003035) software resource A command-line utility for bigWig files designed to read bigWig files rapidly and efficiently, providing functionality for extracting data and summarizing it in several ways, globally or at specific regions. Its functionality is subdivided into subprograms that roughly fall into three categories: data extraction, analysis, and data modification, although e.g. in the case of the matrix program or the sax program, the boundary between data extraction and analysis isn't very strong. The data modification programs all have the behavior that a bigWig is inputted and a new bigWig is outputted. standalone software, unix/linux, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:2448936 Free, Available for download, Freely available biotools:bwtool, OMICS_05125 https://bio.tools/bwtool SCR_003035 2026-08-01 12:02:00 21
SMRT View
 
Resource Report
Resource Website
1+ mentions
SMRT View (RRID:SCR_003029) software resource An open source Genome Browser that visualizes data generated by PacBio Sequencing Systems. * Users can explore and interact with all types of analysis results, including resequencing, De novo, cDNA, and barcoding. * Users can also visualize base modifications, base identification and motifs analysis results. standalone software, unix/linux, mac os x, windows, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
Free, Freely available biotools:smrt_view, OMICS_05137 https://bio.tools/smrt_view SCR_003029 SMRT-View 2026-08-01 12:02:24 9
ProRata
 
Resource Report
Resource Website
1+ mentions
ProRata (RRID:SCR_002988) software resource A quantitative proteomics software program for accurate protein abundance ratio estimation with confidence interval evaluation. standalone software, mass spectrometry, proteomics, stable isotope labeling, quantitative proteomics, proteomics, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
PMID:17037911 GNU General Public License, v3 biotools:prorata, OMICS_02502 https://bio.tools/prorata SCR_002988 ProRata: A quantitative proteomics program for accurate protein abundance ratio estimation with confidence interval evaluation, prorata - Quantitative Proteomics Software 2026-08-01 12:01:59 9
rbsurv
 
Resource Report
Resource Website
1+ mentions
rbsurv (RRID:SCR_001175) rbsurv software resource Software package that selects genes associated with survival. microarray, gene, survival, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
Free, Available for download, Freely available biotools:rbsurv, BioTools:rbsurv, OMICS_02088 https://bio.tools/rbsurv, https://bio.tools/rbsurv, https://bio.tools/rbsurv SCR_001175 rbsurv - Robust likelihood-based survival modeling with microarray data 2026-08-01 12:01:24 1
Sherman
 
Resource Report
Resource Website
100+ mentions
Sherman (RRID:SCR_001294) Sherman software resource Software tool to simulate FastQ files for high-throughput sequencing experiments. It allows the user to introduce various "contaminants" into the sequences, such as basecall errors, SNPs, adapter fragments etc., in order to evaluate the influence of common problems observed in many Next-Gen Sequencing experiments. perl, bisulfite sequencing, high-throughput sequencing, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Babraham Institute
Free, Available for download, Freely available biotools:sherman, OMICS_02041 http://www.bioinformatics.babraham.ac.uk/projects/sherman/ SCR_001294 Sherman - bisulfite-treated Read FastQ Simulator 2026-08-01 12:01:37 122

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