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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Pathbase
 
Resource Report
Resource Website
10+ mentions
Pathbase (RRID:SCR_006141) Pathbase image repository, data or information resource, data repository, controlled vocabulary, data access protocol, image collection, database, software resource, storage service resource, ontology, service resource, web service Database of histopathology photomicrographs and macroscopic images derived from mutant or genetically manipulated mice. The database currently holds more than 1000 images of lesions from mutant mice and their inbred backgrounds and further images are being added continuously. Images can be retrieved by searching for specific lesions or class of lesion, by genetic locus, or by a wide set of parameters shown on the Advanced Search Interface. Its two key aims are: * To provide a searchable database of histopathology images derived from experimental manipulation of the mouse genome or experiments conducted on genetically manipulated mice. * A reference / didactic resource covering all aspects of mouse pathology Lesions are described according to the Pathbase pathology ontology developed by the Pathbase European Consortium, and are available at the site or on the Gene Ontology Consortium site - OBO. As this is a community resource, they encourage everyone to upload their own images, contribute comments to images and send them their feedback. Please feel free to use any of the SOAP/WSDL web services. (under development) histopathology, photomicrograph, macroscopic, mutant, genetically manipulated, pathology, transgenic, rodent, mpath ontology, mouse pathology ontology, skinbase, genotype, skin, gene, tissue, hair, mutant mouse strain, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
has parent organization: University of Cambridge; Cambridge; United Kingdom
is parent organization of: Mouse Pathology Ontology
Lesion, Mutant mouse strain, Inbred mouse strain North American Hair Research Society ;
Ellison Medical Foundation ;
European Union QLRI-1999-00320;
European Union LSHG-CT-2006-037188;
NCI CA089713;
NCRR RR17436;
NIH AR49288
PMID:20587689
PMID:15623888
PMID:14681470
Except where otherwise noted, Creative Commons Attribution-NonCommercial-ShareAlike License, v3 Unported, Images on the database remain the property of the persons generously allowing their images to be used and are acknowledged within each record. Images should not be modified, Reproduced or disseminated without the express permission of the submitter. biotools:pathbase, nlx_151637 https://bio.tools/pathbase SCR_006141 Pathbase - European mutant mouse pathology database 2026-08-05 10:44:26 11
DARC - Database for Aligned Ribosomal Complexes
 
Resource Report
Resource Website
10+ mentions
DARC - Database for Aligned Ribosomal Complexes (RRID:SCR_006932) DARC data or information resource, database, model, data analysis service, production service resource, service resource, analysis service resource A database for aligned ribosomal complexes that provides a resource for directly comparing the structures. A collection of files deposited in the RCSB protein data bank and the Electron Microscopy Data Bank have been aligned so as to make direct comparison of the structures possible. An easy-to-use, searchable interface allows users to access and download >130 cryo-EM maps and >300 atomic models in the format of brix and pdb files, respectively. The aligned coordinate system substantially simplifies direct visualization of conformational changes in the ribosome, such as subunit rotation and head-swiveling, as well as direct comparison of bound ligands, such as antibiotics or translation factors. ribosomal complex, cryo-electron microscopy, ribosomal particle, atomic model, ribosome, x-ray crystallography, structure, bio.tools uses: Research Collaboratory for Structural Bioinformatics Protein Data Bank (RCSB PDB)
uses: Electron Microscopy Data Bank at PDBe (MSD-EBI)
is listed by: Debian
is listed by: bio.tools
has parent organization: Ludwig-Maximilians-University; Munich; Germany
DFG SFB594;
DFG SFB646;
DFG WI3285/1-1
PMID:22009674 biotools:darc_site, nlx_149452 https://bio.tools/darc_site SCR_006932 The DARC site, Database for Aligned Ribosomal Complexes, Database for Aligned Ribosomal Complexes (DARC), DARC site 2026-08-05 10:44:34 27
PLEXdb - Plant Expression Database
 
Resource Report
Resource Website
10+ mentions
PLEXdb - Plant Expression Database (RRID:SCR_006963) PLEXdb data or information resource, data repository, portal, storage service resource, topical portal, database, data analysis service, production service resource, service resource, analysis service resource PLEXdb (Plant Expression Database) is a unified gene expression resource for plants and plant pathogens. PLEXdb is a genotype to phenotype, hypothesis building information warehouse, leveraging highly parallel expression data with seamless portals to related genetic, physical, and pathway data. The integrated tools of PLEXdb allow investigators to use commonalities in plant biology for a comparative approach to functional genomics through use of large-scale expression profiling data sets. gene expression, plant, plant pathogen, genotype, phenotype, genetic, physical, pathway, plant biology, compare, functional genomics, expression profiling, expression atlas, pathogen, genome, anova, cluster, bio.tools is listed by: Debian
is listed by: bio.tools
is related to: FuncExpression
has parent organization: Iowa State University; Iowa; USA
UniNSF DBI-0543441;
NSF IOS-0922746;
USDA 3625-21000-049-00D
PMID:22084198 biotools:plexdb, r3d100011516, nlx_149236 https://bio.tools/plexdb, https://doi.org/10.17616/R39D13 SCR_006963 PLEXdb - Gene expression resources for plants and plant pathogens, Plant Expression Database 2026-08-05 10:44:34 21
HTSeq
 
Resource Report
Resource Website
5000+ mentions
HTSeq (RRID:SCR_005514) HTSeq data processing software, authoring tool, software application, standalone software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software Python package that provides infrastructure to process data from high-throughput sequencing assays. While the main purpose of HTSeq is to allow you to write your own analysis scripts, customized to your needs, there are also a couple of stand-alone scripts for common tasks that can be used without any Python knowledge. python, high-throughput sequencing assay, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: European Molecular Biology Laboratory
DOI:10.1093/bioinformatics/btu638 THIS RESOURCE IS NO LONGER IN SERVICE biotools:htseq, OMICS_01053 https://bio.tools/htseq http://www-huber.embl.de/users/anders/HTSeq/, https://sources.debian.org/src/python3-htseq/ SCR_005514 HTSeq: Analysing high-throughput sequencing data with Python 2026-08-05 10:44:16 8587
GeneTalk
 
Resource Report
Resource Website
10+ mentions
GeneTalk (RRID:SCR_005231) GeneTalk data or information resource, data repository, narrative resource, portal, community building portal, database, storage service resource, blog, service resource A web-based tool, knowledgebase and community for analysis and interpretation of human variant files. VCFs (Variant Call Formats) are preprocessed and annotated, you can filter them, access all databases and provide your expertise to the community by creating annotations. sequence variant, annotation, exome sequencing, genetic variant, gene, data sharing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:22826540 The community can contribute to this resource, Free, (during beta period) OMICS_00270, biotools:genetalk https://bio.tools/genetalk SCR_005231 GeneTalk - The Professional Network and Online Tool for Geneticists 2026-08-05 10:44:12 29
MUSCLE
 
Resource Report
Resource Website
10000+ mentions
MUSCLE (RRID:SCR_011812) MUSCLE data processing software, software application, image analysis software, alignment software, data analysis software, software resource, data analysis service, production service resource, service resource, analysis service resource Multiple sequence alignment method with reduced time and space complexity.Multiple sequence alignment with high accuracy and high throughput. Data analysis service for multiple sequence comparison by log- expectation. bio.tools is used by: TranslatorX
is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: PREFAB
has parent organization: European Bioinformatics Institute
PMID:15034147
PMID:15318951
DOI:10.1093/nar/gkh340
biotools:muscle, OMICS_00982 https://bio.tools/muscle, http://www.drive5.com/muscle/, https://www.drive5.com/muscle/manual/, https://www.drive5, http://bioconductor.org/packages/release/bioc/html/muscle.html.com/muscle/manual/install.html, https://sources.debian.org/src/muscle/ SCR_011812 MUltiple Sequence Comparison by Log- Expectation 2026-08-05 10:45:37 16137
neXtProt
 
Resource Report
Resource Website
100+ mentions
neXtProt (RRID:SCR_008911) data or information resource, topical portal, portal, database THIS RESOURCE IS NO LONGER IN SERVICE. Documented on April 15,2025. Human protein knowledge platform. Knowledge platform for human proteins selects and filters high throughput data pertinent to human proteins from UniProtKB. Extends UniProtKB/Swiss-Prot annotations for human proteins to include several new data types. Protein, proteomics, sirna, 3d, pathway, variant, protein-protein interaction, protein-drug interaction, bio.tools, FASEB list is listed by: Debian
is listed by: bio.tools
is related to: UniProtKB
has parent organization: SIB Swiss Institute of Bioinformatics
Swiss Commission for Technology and Innovation ;
SIB
PMID:22139911 THIS RESOURCE IS NO LONGER IN SERVICE biotools:nextprot, nlx_151482 https://bio.tools/nextprot SCR_008911 2026-08-05 10:45:10 166
Bioinformatic Harvester IV (beta) at Karlsruhe Institute of Technology
 
Resource Report
Resource Website
1000+ mentions
Bioinformatic Harvester IV (beta) at Karlsruhe Institute of Technology (RRID:SCR_008017) data or information resource, data processing software, data acquisition software, software application, software resource, database Harvester is a Web-based tool that bulk-collects bioinformatic data on human proteins from various databases and prediction servers. It is a meta search engine for gene and protein information. It searches 16 major databases and prediction servers and combines the results on pregenerated HTML pages. In this way Harvester can provide comprehensive gene-protein information from different servers in a convenient and fast manner. As full text meta search engine, similar to Google trade mark, Harvester allows screening of the whole genome proteome for current protein functions and predictions in a few seconds. With Harvester it is now possible to compare and check the quality of different database entries and prediction algorithms on a single page. Sponsors: This work has been supported by the BMBF with grants 01GR0101 and 01KW0013. function, gene, bioinformatics, data, database, human, meta search engine, prediction, protein, bio.tools, FASEB list is listed by: bio.tools
is listed by: Debian
has parent organization: Karlsruhe Institute of Technology; Karlsruhe; Germany
biotools:harvester, nif-0000-10169 https://bio.tools/harvester SCR_008017 Harvester IV 2026-08-05 10:44:53 1480
PLINK/SEQ
 
Resource Report
Resource Website
50+ mentions
PLINK/SEQ (RRID:SCR_013193) software toolkit, software application, software library, software resource An open-source C/C++ library for working with human genetic variation data. The specific focus is to provide a platform for analytic tool development for variation data from large-scale resequencing projects, particularly whole-exome and whole-genome studies. However, the library could in principle be applied to other types of genetic studies, including whole-genome association studies of common SNPs. (entry from Genetic Analysis Software) gene, genetic, genomic, c/c++, r, macos, linux, bio.tools is listed by: Genetic Analysis Software
is listed by: bio.tools
is listed by: Debian
is related to: PLINK
has parent organization: Harvard University; Cambridge; United States
Open unspecified license nlx_154213, biotools:plink-seq https://bio.tools/plink-seq SCR_013193 2026-08-05 10:45:57 77
Gwyddion
 
Resource Report
Resource Website
1000+ mentions
Gwyddion (RRID:SCR_015583) software resource, data processing software, software application, data analysis software Modular program for SPM (scanning probe microscopy) data visualization and analysis. Primarily it is intended for the analysis of height fields obtained by scanning probe microscopy techniques (AFM, MFM, STM, SNOM/NSOM) and it supports a lot of SPM data formats. However, it can be used for general height field and (greyscale) image processing, for instance for the analysis of profilometry data or thickness maps from imaging spectrophotometry. spm data analysis, spm data visualization, height field analysis is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
Czech Metrology Institute Department of Nanometrology DOI:10.2478/s11534-011-0096-2 Open source OMICS_07548 https://sources.debian.org/src/gwyddion/ SCR_015583 2026-08-05 10:46:25 1510
PASA
 
Resource Report
Resource Website
500+ mentions
PASA (RRID:SCR_014656) data processing software, software application, sequence analysis software, data analysis software, software resource Gene structure annotation and analysis tool that uses spliced alignments of expressed transcript sequences to automatically model gene structures. It also incorporates gene structures based on transcript alignments into existing gene structure annotations. It is one component of a larger eukayotic annotation pipeline implemented at the Broad Institute. gene structure, annotation, gene structure analysis tool, spliced alignment, transcript sequence, bio.tools is used by: BRO_annotation
is listed by: Debian
is listed by: bio.tools
DOI:10.1093/nar/gkg770 Available for download biotools:PASA https://bio.tools/PASA SCR_014656 Program to Assemble Spliced Alignments (PASA), Program to Assemble Spliced Alignments 2026-08-05 10:46:10 999
Molecular Dynamics Workflow (BioKepler)
 
Resource Report
Resource Website
1+ mentions
Molecular Dynamics Workflow (BioKepler) (RRID:SCR_014389) data processing software, software application, workflow software, software resource A workflow for running molecular dynamics simulations. It can be used for all-atom molecular dynamic simulations, which involve five steps of minimization, one step of heating, three steps of equilibration, and one or more instances of production. The input is a set of directories that include the MD simulation input scripts, system topology and coordinate files. Output files are list of plots, simulation trajectories, intermediate files, restart files, and the like. workflow, MD, molecular dynamics, simulation, software, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: bioKepler
has parent organization: University of California at San Diego; California; USA
NIGMS P41GM103426 Requires Linux biotools:ambergpumdsimulation http://nbcr.ucsd.edu/data/downloads/workflows/, https://bio.tools/ambergpumdsimulation SCR_014389 Molecular Dynamics Workflow, AmberGPUMDSimulation, Molecular Dynamics Workflow Software, Amber GPUMD Simulation 2026-08-05 10:46:05 1
Computational Structural Biology Toolbox
 
Resource Report
Resource Website
Computational Structural Biology Toolbox (RRID:SCR_016065) CSB software toolkit, software library, software resource Software package as an application framework and a Python class library. It is designed for reading, storing and analyzing biomolecular structures in a variety of formats with rich support for statistical analyses. software, library, Python, reading, storing, analysis, biomolecular, variety, statistical, analysis, bioinformatic is listed by: Debian
is listed by: OMICtools
Deutsche Forschungsgemeinschaft (DFG) grant HA 5918/1-1;
Max Planck Society
PMID:22942023 Free, Available for download OMICS_09827 https://sources.debian.org/src/csb/ SCR_016065 Computational Structural Biology Toolbox (CSB), CSB Toolbox 2026-08-05 10:46:32 0
HiC-Pro
 
Resource Report
Resource Website
100+ mentions
HiC-Pro (RRID:SCR_017643) data processing software, software application, workflow software, software resource Software tool as optimized and flexible pipeline for Hi-C data processing. Used to process Hi-C data, from raw fastq files, paired end Illumina data, to normalized contact maps. Hi-C, data, raw, fastq, file, paired, Illumina, normalized, contact, map, bio.tools is listed by: Debian
is listed by: bio.tools
France Genomique National infrastructure ;
Labex Deep ;
European Research Coucil ;
ERC Advanced Investigator award ;
European Commission ;
ABS4NGS project ;
National Human Genome Research Institute ;
Paris Alliance of Cancer Research Institutes ;
Howard Hughes Medical Institute
PMID:26619908 Free, Available for download, Freely available biotools:hic-pro https://bio.tools/hic-pro SCR_017643 2026-08-05 10:46:52 206
OrthoFinder
 
Resource Report
Resource Website
1000+ mentions
OrthoFinder (RRID:SCR_017118) software resource, data processing software, software application, data analysis software Software Python application for comparative genomics analysis. Finds orthogroups and orthologs, infers rooted gene trees for all orthogroups and identifies all of gene duplcation events in those gene trees, infers rooted species tree for species being analysed and maps gene duplication events from gene trees to branches in species tree, improves orthogroup inference accuracy. Runs set of protein sequence files, one per species, in FASTA format. comparative, genomic, analysis, find, orthogroup, ortholog, infer, gene, tree, duplicate, accuracy, protein, sequence, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Bill and Melinda Gates Foundation ;
UKAID
PMID:26243257
DOI:10.1101/466201
Free, Available for download, Freely available biotools:OrthoFinder, OMICS_09733, BioTools:OrthoFinder https://bio.tools/OrthoFinder, https://bio.tools/OrthoFinder, https://bio.tools/OrthoFinder SCR_017118 OrthoFinder2, OrthoFinder 2026-08-05 10:46:50 2899
tximport
 
Resource Report
Resource Website
50+ mentions
tximport (RRID:SCR_016752) software resource, data processing software, software application, data analysis software Software R package for importing pseudoaligned reads into R for use with downstream differential expression analysis. Used for import and summarize transcript level estimates for transcript and gene level analysis. pseudoaligned, reads, R, differential, expression, analysis, gene, transcript, bio.tools is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
works with: edgeR
works with: DESeq2
SNSF 143883;
European Commission ;
NCI T32 CA009337
DOI:10.12688/f1000research.7563.1 Free, Available for download, Freely available biotools:tximport https://bioconductor.org/packages/tximport/, https://bioconductor.org/packages/devel/bioc/vignettes/tximport/inst/doc/tximport.html, https://github.com/F1000Research/tximport, https://bio.tools/tximport https://zenodo.org/record/35123#.W_w3behKiM8 SCR_016752 tximport v1.4.0 2026-08-05 10:46:39 91
Nephele
 
Resource Report
Resource Website
10+ mentions
Nephele (RRID:SCR_016595) web application, software resource, data analysis service, production service resource, service resource, analysis service resource Cloud based platform for simplified, standardized and reproducible microbiome data analysis. Allows users to process microbiome datasets through pipelines of existing software tools. microbiome, datasets, process, analyze, metagenome, sequencing, data, bio.tools uses: mothur
uses: QIIME
uses: biobakery
uses: A5-miseq
is listed by: NIAID
is listed by: bio.tools
is listed by: Debian
has parent organization: OCICB
NIH Department of Health and Human Services GS35F0373X PMID:29028892 Free, Available for download, Freely available biotools:nephele https://github.com/niaid/Nephele, https://bio.tools/nephele SCR_016595 2026-08-05 10:46:41 27
scanpy
 
Resource Report
Resource Website
100+ mentions
scanpy (RRID:SCR_018139) software resource, data processing software, software application, data analysis software Software Python tool for large scale single cell gene expression data analysis. Integrates analysis possibilities of established R-based frameworks, provides pre processing, visualization, graph-drawing and diffusion maps, clustering, identification of marker genes for clusters via differential expression tests and pseudo temporal ordering via diffusion pseudo time. Large scale, single cell, gene expression, data analysis, R, pre processing, visualization, graph drawing, diffusion map, clustering, marker gene, differential expression test, bio.tools uses: BBKNN
is used by: triku
is used by: MUON
is listed by: Debian
is listed by: bio.tools
is related to: Anndata
has plug in: infercnvpy
Helmholtz Postdoc Programme ;
German Research Foundation
PMID:29409532 Free, Available for download, Freely available biotools:scanpy, BioTools:scanpy https://icb-scanpy.readthedocs-hosted.com/en/stable/, https://bio.tools/scanpy, https://bio.tools/scanpy, https://bio.tools/scanpy SCR_018139 Single Cell Analysis in Python 2026-08-05 10:47:00 221
Drop-seq tools
 
Resource Report
Resource Website
50+ mentions
Drop-seq tools (RRID:SCR_018142) software resource, data processing software, software application, data analysis software Software Java tools for analyzing Drop-seq data. Used to analyze gene expression from thousands of individual cells simultaneously. Analyzes mRNA transcripts while remembering origin cell transcript. Simultaneous analysis, Drop-seq data, gene expression, thousands individual cells is listed by: Debian
has parent organization: Broad Institute
Stanley Center for Psychiatric Research ;
MGH Psychiatry Residency Research Program ;
Stanley-MGH Fellowship in Psychiatric Neuroscience ;
Stewart Trust Fellows Award ;
Simons Foundation ;
NHGRI P50 HG006193;
Klarman Cell Observatory ;
NIMH U01 MH105960;
NIMH R25 MH094612;
NICHD F32 HD075541;
NSF ECS 0335765;
NSF DMR 1310266;
NSF DMR 1420570
PMID:26000488 https://sources.debian.org/src/drop-seq-tools/ SCR_018142 Droplet sequencing tools, Droplet sequencing data analysis software tools 2026-08-05 10:46:57 94
DrivAER
 
Resource Report
Resource Website
1+ mentions
DrivAER (RRID:SCR_019076) software resource, data processing software, software application, data analysis software Software tool as method for identification of driving transcriptional programs based on AutoEncoder derived Relevance scores. Infers relevance scores for transcriptional programs with respect to specified outcomes of interest in single-cell RNA sequencing data, such as psuedotemporal ordering or disease status.Used for manifold interpretation in scRNA-seq data. Manifold interpretation, scRNAseq data, relevance scores infering, transcriptional program, psuedotemporal ordering, disease status, data, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:drivaer https://bio.tools/drivaer SCR_019076 Driving transcriptional programs using AutoEncoder based Relevance scores 2026-08-05 10:47:09 1

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