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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
SNAVI
 
Resource Report
Resource Website
SNAVI (RRID:SCR_000091) software resource Desktop application for analysis and visualization of large-scale cell signaling networks. standalone software, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Google Code
PMID:19154595 Free, Available for download, Freely available biotools:snavi, OMICS_04122 https://bio.tools/snavi SCR_000091 Signaling Networks Analysis and Visualization 2026-08-01 12:01:08 0
Megraft
 
Resource Report
Resource Website
Megraft (RRID:SCR_000240) Megraft software resource A software package to graft ribosomal small subunit (16S/18S) fragments onto full-length sequences for accurate species richness and sequencing depth analysis in pyrosequencing-length metagenomes. windows, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:22824070 Free, Available for download, Freely available biotools:megraft, OMICS_02161 https://bio.tools/megraft SCR_000240 2026-08-01 12:01:14 0
VARiD
 
Resource Report
Resource Website
VARiD (RRID:SCR_000241) VARiD software resource Software using a Hidden Markov Model for SNP (single nucleotide polymorphism) and indel identification with AB-SOLiD color-space as well as regular letter-space reads. c, single nucleotide polymorphism, indel, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Toronto; Ontario; Canada
PMID:20529926 Free, Available for download, Freely available OMICS_02163, biotools:varid https://bio.tools/varid SCR_000241 2026-08-01 12:01:12 0
TAPIR: target prediction for plant microRNAs
 
Resource Report
Resource Website
10+ mentions
TAPIR: target prediction for plant microRNAs (RRID:SCR_000237) TAPIR Web server designed for prediction of plant microRNA targets. prediction of plant microRNA targets, microrna, target, fasta, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: Ghent University; Ghent; Belgium
has parent organization: VIB; Flanders; Belgium
PMID:20430753 biotools:tapir, OMICS_04004 https://bio.tools/tapir SCR_000237 2026-08-01 12:01:10 10
SODOCK
 
Resource Report
Resource Website
1+ mentions
SODOCK (RRID:SCR_000193) software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on July 31,2025. An optimization algorithm based on particle swarm optimization (PSO) for solving flexible protein-ligand docking problems. particle swarm optimization, protein, ligand, docking, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: National Chiao Tung University; Hsinchu; Taiwan
PMID:17186483 THIS RESOURCE IS NO LONGER IN SERVICE biotools:sodock, OMICS_01606 https://bio.tools/sodock SCR_000193 2026-08-01 12:01:12 1
Quant
 
Resource Report
Resource Website
Quant (RRID:SCR_000267) software resource A software tool for the proteomics community that may help improving analysis of proteomic experimental data. standalone software, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:17584939 Free, Available for download, Freely available OMICS_02504, biotools:quant https://bio.tools/quant SCR_000267 2026-08-01 12:01:10 0
PeptideProphet
 
Resource Report
Resource Website
1+ mentions
PeptideProphet (RRID:SCR_000274) software resource Software that automatically validates peptide assignments to MS/MS spectra made by database search programs such as SEQUEST. standalone software, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: SourceForge
PMID:12403597 Free, Available for download, Freely available OMICS_02520, biotools:peptideprophet https://bio.tools/peptideprophet SCR_000274 2026-08-01 12:01:10 4
GraphProt
 
Resource Report
Resource Website
10+ mentions
GraphProt (RRID:SCR_005842) GraphProt software resource Software for modeling binding preferences of RNA-binding proteins from high-throughput experiments such as CLIP-seq and RNAcompete. sequence-binding preference, structure-binding preference, rna-binding protein, high-throughput sequencing, clip-seq, rnacompete, rna, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Freiburg; Baden-Wurttemberg; Germany
PMID:24451197 Free, Public OMICS_02252, biotools:graphprot https://bio.tools/graphprot SCR_005842 2026-08-01 12:03:02 36
Cascade
 
Resource Report
Resource Website
50+ mentions
Cascade (RRID:SCR_005861) Cascade software resource R software package to study, predict and simulate the diffusion of a signal through a temporal gene network. It predicts changes in gene expressions after a biological perturbation in the network and provides graphical outputs that allow monitoring the spread of a signal through the network., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. r, windows, gene expression, perturbation, network, diffusion, signal, temporal gene network, gene regulatory network, gene, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Strasbourg; Strasbourg; France
PMID:24307703 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02249, biotools:cascade http://www-math.u-strasbg.fr/genpred/spip.php?rubrique4, https://bio.tools/cascade SCR_005861 2026-08-01 12:03:00 92
BiNGO: A Biological Networks Gene Ontology tool
 
Resource Report
Resource Website
500+ mentions
BiNGO: A Biological Networks Gene Ontology tool (RRID:SCR_005736) BiNGO software resource The Biological Networks Gene Ontology tool (BiNGO) is an open-source Java tool to determine which Gene Ontology (GO) terms are significantly overrepresented in a set of genes. BiNGO can be used either on a list of genes, pasted as text, or interactively on subgraphs of biological networks visualized in Cytoscape. BiNGO maps the predominant functional themes of the tested gene set on the GO hierarchy, and takes advantage of Cytoscape''''s versatile visualization environment to produce an intuitive and customizable visual representation of the results. Platform: Windows compatible, Mac OS X compatible, Linux compatible, Unix compatible gene ontology, gene, ontology, statistical analysis, term enrichment, biological network, plugin, bio.tools is listed by: Gene Ontology Tools
is listed by: bio.tools
is listed by: Debian
is related to: Gene Ontology
is related to: Cytoscape
has parent organization: Ghent University; Ghent; Belgium
PMID:15972284 Open unspecified license - Free for academic use nlx_149196, biotools:bingo https://bio.tools/bingo SCR_005736 Biological Networks Gene Ontology 2026-08-01 12:02:58 790
h5vc
 
Resource Report
Resource Website
1+ mentions
h5vc (RRID:SCR_006039) h5vc software resource Software package that contains functions to interact with tally data from Next-Generation Sequencing (NGS) experiments that is stored in HDF5 files. next-generation sequencing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
PMID:24451629 GNU General Public License, v3 or newer biotools:h5vc, OMICS_02243 http://www.ebi.ac.uk/~pyl/h5vc/, https://bio.tools/h5vc SCR_006039 h5vc - Scalable nucleotide tallies with HDF5, h5vc - Managing alignment tallies using a hdf5 backend 2026-08-01 12:03:03 2
IRanges
 
Resource Report
Resource Website
50+ mentions
IRanges (RRID:SCR_006420) IRanges software resource Software tool for computing and annotating genomic ranges.Provides efficient low-level and highly reusable S4 classes for storing ranges of integers, RLE vectors (Run-Length Encoding), and, more generally, data that can be organized sequentially (formally defined as Vector objects), as well as views on these Vector objects. Efficient list-like classes are also provided for storing big collections of instances of the basic classes. All classes in the package use consistent naming and share the same rich and consistent Vector API as much as possible. Annotating genomic ranges, computing genomic ranges, genomic ranges, storing ranges of integers, bio.tools is used by: riboWaltz
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:23950696 Free, Available for download, Freely available OMICS_01163, biotools:iranges https://bio.tools/iranges SCR_006420 Infrastructure for manipulating intervals on sequences 2026-08-01 12:03:09 77
VICUNA
 
Resource Report
Resource Website
10+ mentions
VICUNA (RRID:SCR_006302) VICUNA software resource A de novo assembly program targeting populations with high mutation rates. c++, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Broad Institute
PMID:22974120 biotools:vicuna, OMICS_02162 https://bio.tools/vicuna SCR_006302 2026-08-01 12:03:08 26
MSIsensor
 
Resource Report
Resource Website
100+ mentions
MSIsensor (RRID:SCR_006418) MSIsensor software resource A C++ software program for automatically detecting somatic and germline variants at microsatellite regions. It computes length distributions of microsatellites per site in paired tumor and normal sequence data, subsequently using these to statistically compare observed distributions in both samples. c++, somatic variant, germline variant, microsatellite, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
Tumor, Normal PMID:24371154 Copyrighted, See LICENSE biotools:msisensor, OMICS_02192 https://bio.tools/msisensor SCR_006418 2026-08-01 12:03:08 156
TSSer
 
Resource Report
Resource Website
TSSer (RRID:SCR_006419) TSSer software resource A computational pipeline to analyze differential RNA sequencing (dRNA-seq) data to determine transcription start sites genome-wide. differential rna sequencing, transcription start site, rna-seq, genome, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Basel; Basel; Switzerland
PMID:24371151 GNU General Public License biotools:tsser, OMICS_02191 https://bio.tools/tsser SCR_006419 TSSer: a computational pipeline to identify transcription start sites in bacterial genomes 2026-08-01 12:03:11 0
COHCAP
 
Resource Report
Resource Website
10+ mentions
COHCAP (RRID:SCR_006499) COHCAP software resource An algorithm to analyze single-nucleotide resolution methylation data (Illumina 450k methylation array, targeted BS-Seq, etc.). It provides QC metrics, differential methylation for CpG Sites, differential methylation for CpG Islands, integration with gene expression data, and visualization of methylation values. java, perl, s/r, java swing, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: SourceForge
PMID:23598999 Acknowledgement requested, Attribution Assurance License biotools:cohcap, OMICS_00595 https://bio.tools/cohcap SCR_006499 City of Hope CpG Island Analysis Pipeline, COHCAP - City of Hope CpG Island Analysis Pipeline 2026-08-01 12:03:09 18
FLUX CAPACITOR
 
Resource Report
Resource Website
1+ mentions
FLUX CAPACITOR (RRID:SCR_006651) FLUX CAPACITOR software resource Software to recontruct abundances of known transcript forms from RNAseq data. The algorithm works by distributing the reads mapping to a given exonic region (or splice junction) among the transcripts including the exon (or splice junction). The input is the annotation of a reference transcriptome and reads from RNAseq technologies aligned to the genome. From the reference annotation, splicing graphs are produced and reads are mapped to corresponding edges in these graphs according to the position where they align in the genomic sequence. The resulting graph with edges labelled by the number of reads can be interpreted as a flow network where each transcript representing a transportation path from its start to its end and consequently each edge a possibly shared segment of transportation along which a certain number of reads per nucleotide -- i.e., a flux -- is observed. Given a density function of reads along a transcript, the expected participation of each transcript in an edge under consideration can be estimated. The basic idea is to cast back from these latter participations and the observed number of reads - allowing for a certain amount of noise - to the original transcript abundancies. To do so, a linear constraint is formalized for each edge, and an optimal solution for the complete set of constraints is found by a standard linear program solver. bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
PMID:20220756 biotools:the_flux_capacitor, OMICS_01293 https://bio.tools/the_flux_capacitor SCR_006651 The FLUX CAPACITOR, FluxCapacitor 2026-08-01 12:03:14 2
iontree
 
Resource Report
Resource Website
iontree (RRID:SCR_002813) software resource Software package that provides utility functions to manage and analyse MS2/MS3 fragmentation data from ion trap mass spectrometry. It was designed for high throughput metabolomics data with many biological samples and a large numer of ion trees collected. Tests have been done with data from low-resolution mass spectrometry but could be readily extended to precursor ion based fragmentation data from high resoultion mass spectrometry. standalone software, mac os x, unix/linux, windows, r, mass spectrometry, metabolomics, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
PMID:24958264 Free, Freely available, Available for download OMICS_02656, biotools:iontree https://bio.tools/iontree SCR_002813 iontree: Data management and analysis of ion trees from ion-trap mass spectrometry 2026-08-01 12:08:11 0
mzMatch
 
Resource Report
Resource Website
1+ mentions
mzMatch (RRID:SCR_000543) software toolkit, software resource A software to provide small tools for common processing tasks for LC/MS data. It is an extension to the metabolomics analysis pipeline mzMatch.R. The software is modular, open source, platform independent and written in Java. metabolomics, analysis, java, tool, peak extraction, filtering, normalization, derivative detection, identification, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23162054 Free, Available for download, Freely available, biotools:mzmatch, OMICS_02642 https://bio.tools/mzmatch SCR_000543 2026-08-02 09:02:53 5
Bioinformatics Toolkit
 
Resource Report
Resource Website
100+ mentions
Bioinformatics Toolkit (RRID:SCR_010277) software toolkit, software resource A platform that integrates a great variety of tools for protein sequence analysis. Many tools are developed in-house, and serveral public tools are offered with extended functionality. Most frequently used tools HHpred Sensitive protein homology detection and structure prediction by HMM-HMM-comparison. Starting from a query sequence, HHpred builds a multiple sequence alignment using HHblits and turns it into a profile HMM. This is then compared it with a database of HMMs representing proteins with known structure (e.g. PDB, SCOP) or annotated protein families (e.g. PFAM, SMART, CDD, COGs, KOGs). The output is a list of closest homologs with alignments. HHpred can also build 3d homology models using the identified templates in the PDB database. It can optimize template picking and query-template alignments for homology modeling. The HHblits software is part of the open source package HHsuite. HHblits Remote homology detection method based on iterative HMM-HMM comparison. HHblits can build high-quality MSAs starting from single sequences or from MSAs. It transforms these into a query HMM and iteratively searches through uniprot20 or nr20 databases by adding significantly similar sequences from the previous search to the updated query HMM for the next search iteration. Compared to PSI-BLAST, HHblits is faster, up to twice as sensitive and produces more accurate alignments. The HHblits software is part of the open source package HHsuite. Quick2d Quick2D gives you an overview of secondary structure features like alpha-helices, extended beta-sheets, coiled coils, transmembrane helices and disorder regions. Predictions by PSIPRED, JNET, Prof(Rost), Prof(Ouali), Coils, MEMSAT2, HMMTOP, DISOPRED2 and VSL2. Modeller A Program for Comparative Protein Structure Modelling by Satisfaction of Spatial Restraints. Coils/PCoils This server compares a single sequence (COILS) or a sequence alignment (PCOILS) to a database of known coiled-coils and derives a similarity score. The program then calculates the probability that the sequence will adopt a coiled-coil conformation. PSI-Blast Search with an amino acid sequence against protein databases for locally similar sequences. Similar to ProteinBLAST but more sensitive. PSI-BLAST first performs a BLAST search and builds an alignment from the best local hits. This alignment is then used as a query for the next round of search. After each successive round the search alignment is updated. bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
DOI:10.1038/NMETH.1818 nlx_156936, OMICS_28407, biotools:bioinformatics_toolkit https://bio.tools/bioinformatics_toolkit, https://sources.debian.org/src/hhsuite/ SCR_010277 2026-08-02 09:05:41 235

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