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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://pipeline.lbl.gov/cgi-bin/gateway2
Software tools for comparative genomics.Comprehensive suite of programs and databases for comparative analysis of genomic sequences. There are two ways of using VISTA - you can submit your own sequences and alignments for analysis (VISTA servers) or examine pre-computed whole-genome alignments of different species.
Proper citation: VISTA Browser (RRID:SCR_011808) Copy
Data aggregate that compiles results from bioinformatics analyses across multiple samples into a single report. It is written in Python.
Proper citation: MultiQC (RRID:SCR_014982) Copy
http://bioconductor.org/packages/release/bioc/html/topGO.html
Software package which provides tools for testing GO terms while accounting for the topology of the GO graph. Different test statistics and different methods for eliminating local similarities and dependencies between GO terms can be implemented and applied.
Proper citation: topGO (RRID:SCR_014798) Copy
https://sites.google.com/site/danposdoc/
Software toolkit with various functions for the analysis of nucleosome and protein occupancy by sequencing.
Proper citation: DANPOS2 (RRID:SCR_015527) Copy
https://github.com/HASTE-project
Software toolkit for rapid development of cloud native intelligent data pipelines for scientific data streams. Hierarchical approach to acquisition, analysis, and interpretation of image data. Developed in the project Hierarchical Analysis of Spatial and Temporal Data.
Proper citation: HASTE-project (RRID:SCR_020932) Copy
https://mermaid.readthedocs.io/en/latest/
Registration toolbox written in pyTorch. Supports various image registration methods. Focuses on nonparametric registration approaches including stationary velocity fields and large discplacement diffeomorphic metric mapping models though simple affine registration is also possible. Allows for rapid prototyping of new image registration approaches and similarity measures.
Proper citation: MERMAID (RRID:SCR_020939) Copy
https://github.com/theislab/scvelo
Software package for estimating and analyzing RNA velocities in single cells using dynamical modeling. RNA Velocity using dynamical modeling.
Proper citation: scVelo (RRID:SCR_018168) Copy
https://github.com/Ecogenomics/GtdbTk
Open source software tool for assigning objective taxonomic classifications to bacterial and archaeal genomes based on Genome Database Taxonomy. Designed to work with recent advances that allow metagenome assembled genomes to be obtained directly from environmental samples. Can also be applied to isolate and single cell genomes.
Proper citation: GTDB-Tk (RRID:SCR_019136) Copy
https://www.bioconductor.org/packages/release/bioc/html/ensembldb.html
Software R package to create and use Ensembl based annotation resources.
Proper citation: ensembldb (RRID:SCR_019103) Copy
https://gitlab.com/biomerieux-data-science/clustlasso
Software R package to build predictive signatures of microbial phenotypes. Software package implementing cluster lasso approach.
Proper citation: clustLasso (RRID:SCR_018820) Copy
https://github.com/big-data-lab-team/spot
Open source software tool for file based localization of numerical perturbations in data analysis pipelines. Identifies components in pipeline, at resolution level of system process, that produce different results in different execution conditions.
Proper citation: Spot (RRID:SCR_018915) Copy
https://cran.r-project.org/web/packages/GALLO/vignettes/GALLO.html
Software R package developed for accurate annotation of genes and quantitative trait loci located in regions identified in common genomic analyses performed in livestock, such as Genome Wide Association Studies and transcriptomics using RNA-Sequencing. Allows graphical visualization of gene and QTL annotation results, data comparison among different grouping factors like methods, breeds, tissues, statistical models, studies and QTL enrichment in different livestock species including cattle, pigs, sheep, and chickens.
Proper citation: Genomic Annotation in Livestock for positional candidate LOci (RRID:SCR_019212) Copy
https://github.com/SMI/SmiServices
Software suite of tools for cataloguing and anonymising DICOM files, as used for Scottish Medical Imaging project. Software suite of microservices for loading, anonymising, linking and extracting large volumnes of dicom medical images to support medical research. Platform allows dicom tags extracted from clinical images to be loaded into MongoDB and relational database tables for purposes of generating anonymous linked research extracts including image anonymisation.
Proper citation: SMI Services (RRID:SCR_018881) Copy
https://knights-lab.github.io/MLRepo/
Machine learning repository for microbiome datasets.
Proper citation: ML Repo (RRID:SCR_017079) Copy
http://wpicr.wpic.pitt.edu/WPICCompGen/bars.htm
Software application that is a statistical method that bridges the gap between single-locus and haplotype-based tests of association. It is based on the non-parametric regression techniques embodied by Bayesian Adaptive Regression Splines. (entry from Genetic Analysis Software), THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: BARS (RRID:SCR_009123) Copy
https://simtk.org/home/simvascular
Open source software suite for cardiovascular simulation. It includes code for reading 3D images, segmenting structures, generating models and meshes, and modeling blood flow in deformable vessels. The suite also includes tools for physiologic boundary conditions, fluid structure interaction, and an accurate and efficient finite element Navier-Stokes solver. Commercial components have been used in the simulation process, and for these components, the project attempts to provide interfaces that allow substitution of open source components. The SimVascular project is derived from the ASPIRE2 software project and includes modified portions of PHASTA from RPI/SCOREC.
Proper citation: SimVascular (RRID:SCR_002686) Copy
http://www.nest-simulator.org/
Software tool as simulator for spiking neural network models that focuses on dynamics, size and structure of neural systems rather than on exact morphology of individual neurons. Used for any size spiking neurons networks including models of information processing, models of network activity dynamics, models of learning and plasticity.
Proper citation: NEST Simulator (RRID:SCR_002963) Copy
NIH initiative project to provide full-length open reading frame (FL-ORF) clones for human, mouse, and rat genes, cow. MGC cDNA clones were obtained by screening of cDNA libraries, by transcript-specific RT-PCR cloning, and by DNA synthesis of cDNA inserts. All MGC sequences are deposited in GenBank and clones can be purchased from distributors of IMAGE consortium. With conclusion of MGC project in March 2009, GenBank records of MGC sequences will be frozen, without further updates. Since definition of what constitutes full-length coding region for some of genes and transcripts for which they have MGC clones will likely change in future, users planning to order MGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as the UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view relevant regions of genome (browsers) or gene-related information (Entrez Gene).
Proper citation: Mammalian Gene Collection (RRID:SCR_007024) Copy
http://www.helsinki.fi/~tsjuntun/multidiseq/
A multipoint linkage analysis software which allows Marker-Marker LD (entry from Genetic Analysis Software)
Proper citation: MULTIDISEQ (RRID:SCR_009304) Copy
http://www.stat.sinica.edu.tw/hsinchou/genetics/pooledDNA/mpda.htm
A tool for analyzing hybridization intensity data from microarray-based pooled DNA experiments. MPDA was developed under the software platform, MATLABR, and provided user-friendly interfaces adapted to Windows systems (Windows 98, Windows 2000 and Windows XP). or users without installing software MATLABR, we also developed stand-alone executables generated via the MATLABR compiler. MPDA provides four major functions: (1) Whole-genome DNA amplification/hybridization analysis, (2) Allele frequency estimation, (3) Association mapping, (4) Allelic imbalance detection. Graphic and numerical outputs from MPDA support global and detailed inspection for bulk of genomic data. (entry from Genetic Analysis Software)
Proper citation: MPDA (RRID:SCR_009303) Copy
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