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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) data processing software, software application, sequence analysis software, data analysis software, software resource Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks, https://bio.tools/cufflinks, https://sources.debian.org/src/cufflinks/ SCR_014597 2026-08-05 10:46:11 8838
libRoadRunner
 
Resource Report
Resource Website
10+ mentions
libRoadRunner (RRID:SCR_014763) software application, simulation software, software resource Simulation engine for systems and synthetic biology to be used with other software applications. It retains the original functionality of RoadRunner but has changes in performance, back-end design, event handling, new C++ API, and stochastic simulation support. simulation engine, simulation software, road runner, roadrunner, systems biology, synthetic biology is listed by: Debian
is listed by: OMICtools
NIGMS GM081070 DOI:10.1093/bioinformatics/btv363 Open source, Available for download OMICS_09368 https://sources.debian.org/src/libroadrunner-dev/ SCR_014763 2026-08-05 10:46:12 11
Prokka
 
Resource Report
Resource Website
1000+ mentions
Prokka (RRID:SCR_014732) data processing software, software application, sequence analysis software, data analysis software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for the rapid annotation of prokaryotic genomes. It produces GFF3, GBK and SQN files that are ready for editing in Sequin and ultimately submitted to Genbank/DDJB/ENA. A typical 4 Mbp genome can be fully annotated in less than 10 minutes on a quad-core computer, and scales well to 32 core SMP systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. annotation, prokaryote, genome, prokaryotic genome, sequence analysis software, annotation software, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1093/bioinformatics/btu153 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04220, biotools:prokka https://bio.tools/prokka, https://sources.debian.org/src/prokka/, https://sources.debian.org/src/prokka/ SCR_014732 2026-08-05 10:46:11 4876
SeaView
 
Resource Report
Resource Website
1000+ mentions
SeaView (RRID:SCR_015059) data processing software, software application, data visualization software, data analysis software, sequence analysis software, software resource Graphical user interface for multiple sequence alignment and molecular phylogeny. SeaView also generates phylogenetic trees. sequence alignment, molecular phylogeny, phylogenetic tree, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:19854763
DOI:10.1093/molbev/msp259
Free, Available for download OMICS_08908, biotools:seaview https://bio.tools/seaview, https://sources.debian.org/src/seaview/ SCR_015059 2026-08-05 10:46:15 1777
GIIRA
 
Resource Report
Resource Website
1+ mentions
GIIRA (RRID:SCR_015507) data processing software, software application, sequence analysis software, data analysis software, software resource Gene prediction method that identifies potential coding regions based on the mapping of reads from an RNA-Seq experiment. gene prediction, rna seq, coding region, potential coding region is listed by: Debian
is listed by: OMICtools
DOI:10.1093/bioinformatics/btt577 Available for download OMICS_07360 http://www.rki.de/EN/Content/Institute/DepartmentsUnits/JuniorGroups/JRG4.html, https://sources.debian.org/src/giira/ SCR_015507 2026-08-05 10:46:25 3
SEER
 
Resource Report
Resource Website
100+ mentions
SEER (RRID:SCR_015499) data processing software, source code, software application, data analysis software, sequence analysis software, software resource Sequence element enrichment analysis tool to perform pan-genome-wide association studies in bacteria. bacterial genome association, sequence element enrichment analysis, kmer enrichment analysis is listed by: Debian
is listed by: OMICtools
is hosted by: GitHub
DOI:10.1038/ncomms12797
DOI:10.1101/038463
Available for download OMICS_21699 https://sources.debian.org/src/seer/ SCR_015499 2026-08-05 10:46:25 463
Parallel-META
 
Resource Report
Resource Website
1+ mentions
Parallel-META (RRID:SCR_000121) software resource, data processing software, software application, data analysis software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Open source pipeline for metagenomic data analysis, which enables efficient and parallel analysis of multiple metagenomic datasets and visualization of results for multiple samples. Can perform rapid data mining among microbial community data for comparative taxonomic and functional analysis. data mining, microbial community data, comparative taxonomics, metagenomic analysis, parallel algorithms is listed by: OMICtools PMID:23046922 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01519 SCR_000121 Parallel META, Parallel Meta 2026-08-05 10:43:06 4
Orphelia
 
Resource Report
Resource Website
1+ mentions
Orphelia (RRID:SCR_000119) software application, simulation software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 23,2022. A metagenomic open reading frame (ORF) finding tool for the prediction of protein coding genes in short, environmental DNA sequences with unknown phylogenetic origin. The resource is based on a two-stage machine learning approach that uses linear discriminants to extract features from the ORFs. An artificial neural network then combines the features and computes a gene probability for each ORF fragment. metagenomic open reading frame, tool, resource, protein, genes, DNA, phyologenetic origin, machine learning, linear discriminates, artificial neural network, computation, scientific computing, fragment is listed by: OMICtools PMID:19429689 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01492 SCR_000119 2026-08-05 10:43:06 2
RefFinder
 
Resource Report
Resource Website
10+ mentions
RefFinder (RRID:SCR_000472) RefFinder analysis service resource, data access protocol, software resource, production service resource, service resource, web service THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 1,2023. Web-based tool for evaluating and screening reference genes from extensive experimental datasets. It integrates major computational programs (geNorm, Normfinder, BestKeeper, and the comparative delta-Ct method) to compare and rank the tested candidate reference genes. Based on the rankings from each program, it assigns an appropriate weight to an individual gene and calculated the geometric mean of their weights for the overall final ranking., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. gene, gene expression, reference gene, web based tool uses: BestKeeper
uses: NormFinder
uses: geNORM
is listed by: OMICtools
has parent organization: East Carolina University; Carolina; USA
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_02321 http://www.leonxie.com/referencegene.php SCR_000472 2026-08-05 10:43:10 45
RSEM
 
Resource Report
Resource Website
50+ mentions
RSEM (RRID:SCR_000262) software resource, data processing software, software application, data analysis software Software package for quantifying gene and isoform abundances from single end or paired end RNA Seq data. Accurate transcript quantification from RNA Seq data with or without reference genome. Used for accurate quantification of gene and isoform expression from RNA-Seq data. quantifying, gene, isoform, abundance, single, end, paired, RNA seq, data, transcript, reference, genome, bio.tools is listed by: OMICtools
is listed by: GitHub
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Wisconsin-Madison; Wisconsin; USA
PMID:21816040 Free, Available for download, Freely available OMICS_01966, OMICS_01287, biotools:rsem, SCR_013027 https://github.com/deweylab/RSEM, https://github.com/deweylab/RSEM/releases, https://bio.tools/rsem, https://sources.debian.org/src/rsem/ SCR_000262 RSEM, RNA-Seq by Expectation-Maximization, RSEM-v1.3.0 2026-08-05 10:43:08 94
PSCBS
 
Resource Report
Resource Website
PSCBS (RRID:SCR_000417) data processing software, software application, sequence analysis software, data analysis software, software resource Software R package for segmentation of allele-specific DNA copy number data and detection of regions with abnormal copy number within each parental chromosome. Both tumor-normal paired and tumor-only analyses are supported. abnormal copy number regions detection, allele specific DNA copy number data segmentation, is listed by: OMICtools
is listed by: Debian
is related to: CRAN
has parent organization: University of California at San Francisco; California; USA
PMID:21666266
DOI:10.1093/bioinformatics/btr329
Free, Available for download, Freely available OMICS_05545 https://sources.debian.org/src/r-cran-pscbs/ SCR_000417 PSCBS: Analysis of Parent-Specific DNA Copy Numbers 2026-08-05 10:43:09 0
BSmooth-align
 
Resource Report
Resource Website
1+ mentions
BSmooth-align (RRID:SCR_000013) data processing software, image analysis software, software application, alignment software, data analysis software, software resource Software statistics and alignment pipeline that performs the alignment of bisulfite sequence reads and tabulates read-level methylation measurements. bisulfite sequence, read-level methylation, bisulfite sequence reads alignment, is listed by: OMICtools Free, Available for download, Freely available OMICS_01846 SCR_000013 2026-08-05 10:43:05 1
Sequence Read Format
 
Resource Report
Resource Website
1+ mentions
Sequence Read Format (RRID:SCR_000132) SRF data or information resource, standard specification, narrative resource, interchange format A generic format for DNA sequence data. The primary motivation for creating SRF has been to enable a single format capable of storing data generated by any DNA sequencing technology. dna sequence, dna sequencing, interchange format is listed by: OMICtools
has parent organization: SourceForge
Public, A C++ implementation of Sequence Read Format is available OMICS_05130 SCR_000132 Sequence Read Format (SRF) 2026-08-05 10:43:06 1
GMATo
 
Resource Report
Resource Website
1+ mentions
GMATo (RRID:SCR_000165) data processing software, software application, sequence analysis software, data analysis software, software resource A software tool used for simple sequence repeats (SSR) or microsatellite characterization. It also facilitates SSR marker design on a genomic scale, microsatellite mining at any length, and comprehensive statistical analysis for DNA sequences in any genome at any size. Analysis parameters are customizable. simple sequence repeat, ssr, microsatellite, genomic, marker design, sequence analysis software is listed by: OMICtools
has parent organization: SourceForge
PMID:23861572 Free, Available for download, Freely available OMICS_00106 SCR_000165 Genome-wide Microsatellite Analyzing Tool, Genome Microsatellite Analyzing Tool, Genome-wide Microsatellite Analyzing Tool (GMATo) 2026-08-05 10:43:07 1
DESeq
 
Resource Report
Resource Website
100+ mentions
DESeq (RRID:SCR_000154) DESeq software resource, data processing software, software application, data analysis software THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 30,2023. Software for differential gene expression analysis based on the negative binomial distribution. It estimates variance-mean dependence in count data from high-throughput sequencing assays and tests for differential expression. gene expression, binomial, differential, negative binomial distribution, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is hosted by: Bioconductor
PMID:20979621
DOI:10.1186/s13059-014-0550-8
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01306, biotools:deseq https://bio.tools/deseq, https://sources.debian.org/src/r-bioc-deseq2/ SCR_000154 2026-08-05 10:43:07 473
POPBAM
 
Resource Report
Resource Website
POPBAM (RRID:SCR_000464) POPBAM software resource, data processing software, software application, data analysis software A tool to perform evolutionary or population-based analyses of next-generation sequencing data. POPBAM takes a BAM file as its input and can compute many widely used evolutionary genetics measures in sliding windows across a genome. next-generation sequencing, evolution, population, bam, genome, evolutionary genetics, c++, short read, sequence alignment, sliding window, command-line, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
has parent organization: University of Rochester; New York; USA
PMID:24027417 Free, Available for download, Freely available biotools:popbam, OMICS_01559 https://bio.tools/popbam http://popbam.sourceforge.net/ SCR_000464 2026-08-05 10:43:10 0
Glide
 
Resource Report
Resource Website
10+ mentions
Glide (RRID:SCR_000187) Glide software application, simulation software, software resource Software package which approximates a complete search of the conformational, orientational, and positional space of the ligand in a given receptor. Used in drug development for predicting protein ligand binding modes and ranking ligands via high throughput virtual screening. ligand, receptor, docking, computation, virtual, screening, drug, discovery is listed by: OMICtools
is listed by: SoftCite
has parent organization: Schrodinger
works with: Ligprep
PMID:18428795 Restricted OMICS_01601 SCR_000187 2026-08-05 10:43:07 15
GASV
 
Resource Report
Resource Website
1+ mentions
GASV (RRID:SCR_000061) GASV software resource, data processing software, software application, data analysis software Software tool for identifying structural variants (SVs) from paired-end sequencing data.GASV distribution includes three components that are typically run in succession: the BAM file of unique paired-read mappings is processed; structural variants are identified by clustering discordant fragments; and a probabilistic algorithm improves the specificity of GASV predictions. paired-end sequencing data, structural variant, probabilistic algorithm, discordant fragment, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
is related to: GASVPro
has parent organization: Brown University; Rhode Island; USA
Burroughs Wellcome Fund ;
Department of Defense Breast Cancer Research ;
ADVANCE Program at Brown University ;
NSF 0548311
PMID:19477992 Free, Available for download, Freely available biotools:gasv, OMICS_01352 http://compbio.cs.brown.edu/projects/gasv/, https://bio.tools/gasv SCR_000061 Geometric Analysis of Structural Variants 2026-08-05 10:43:06 4
rtd
 
Resource Report
Resource Website
rtd (RRID:SCR_000337) software resource, data processing software, software application, data analysis software Reference-free ddRADseq analysis software tools. The pipeline script generates reference-sorted, indexed BAM from uniqued reads from radtag sequencing lanes. standalone software is listed by: OMICtools PMID:22675423 Free, Available for download, Freely available OMICS_03723 SCR_000337 2026-08-05 10:43:09 0
ChIPmeta
 
Resource Report
Resource Website
ChIPmeta (RRID:SCR_000054) software resource, data processing software, software application, data analysis software Software using a Hierarchical hidden Markov model for jointly analyzing ChIP-chip and ChIP-seq datasets. chip-chip, chip-seq, ChIP-chip and ChIP-seq datasets analysis, is listed by: OMICtools Free, Available for download, Freely available OMICS_02172 SCR_000054 ChIPmeta with HHM 2026-08-05 10:43:05 0

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