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https://biofilmlab.org/

Core offers imaging and analysis of intact biofilms to capture with ultimate precision the position, interactions, activity, and identification of microbes in real-time from intact samples. With our broad range of analytical capabilities, we can determine how microbes are interacting and altering their environmental conditions. We provide one-on-one training, method development, proposal writing, troubleshooting and data analysis services to help you meet your biofilm-related analytical and imaging needs.

Proper citation: Montana State University CBE Bioimaging and Analytical Core Facility (RRID:SCR_026519) Copy   

•   Source: SciCrunch Registry

https://resuscitationscience.com/biomarker-assay-instrumentation/

Core provides access to XFe 96 Extracellular Flux Analyzer, seahorse technology, as well as additional services that include technical advice in experimental design, data analysis and basic training. Provides access to electrochemiluminescence immunoassays using MESO QuickPlex SQ 120. You can perform multiplex biomarker and cytokine assays, test for immunogenicity or toxicity, or we can help you develop your own unique assays. Core also provides access to ImageXpress Pico, the next generation of digital microscopy and access to SPECTRAMAX I3X, multi-mode microplate reader.

Proper citation: Beth Israel Deaconess Medical Center Biomarker and Metabolism Research Core Facility (RRID:SCR_026518) Copy   

•   Source: SciCrunch Registry

https://research.vcu.edu/cores/structural-biology/

Provides access to equipment, offering researchers capability to determine 3D structure of macromolecules and macromolecular complexes. Provides services for structure-based drug design, protein-ligand or DNA binding studies, testing mutational effects on target macromolecules, and finding the absolute stereochemistry of chiral compounds. Offers training, technical support, and collaborative opportunities, which are crucial for structural biologists and other researchers studying structure of biological macromolecules and other materials.Core encompasses X-ray crystallography, Cryo-Electron Microscopy (Cryo-EM), and Nuclear Magnetic Resonance (NMR) facilities, and is also closely associated with the School of Pharmacy Molecular Modeling facility.

Proper citation: Virginia Commonwealth University VCU Structural Biology Core Facility (RRID:SCR_026455) Copy   

•   Source: SciCrunch Registry

https://www.lerner.ccf.org/cores/flow-cytometry/

Core provides investigators with resource for quantitative studies of cells, extracellular vesicles, and single-cell gene transcriptome analyses. Offers sample acquisition and analysis, cell sorting, and consultation for experimental design, interpretation and troubleshooting.

Proper citation: Cleveland Clinic Research Flow Cytometry Core Facility (RRID:SCR_026460) Copy   

•   Source: SciCrunch Registry

https://research.vcu.edu/cores/barc/

Core offers comprehensive instrumentation and technical support for all aspects of in vitro and in vivo pre-clinical non-human anatomical and molecular imaging. Studies may be conducted on samples prepared to exhibit characteristic features for a particular imaging modality. Within the intact environment, physiological and pathophysiological activity may be observed through imaging or numerous biological pathways and interactions involved in injury and disease progression, such as traumatic brain injury, cardiac disease, tumorigenesis, and therapeutic interventions.

Proper citation: Virginia Commonwealth University VCU Bioimaging and Applied Research Core Facility (RRID:SCR_026429) Copy   

•   Source: SciCrunch Registry

https://www.mayo.edu/research/core-resources/stem-cell-organoid-core/overview

Core provides researchers with access to high-quality human induced-pluripotent stem cell (iPSC) production, expansion, validation, and quality control services, while strictly adhering to approved protocols, ensuring high-quality standards and consistency throughout the process.

Proper citation: Mayo Clinic Stem Cell and Organoid Core Facility (RRID:SCR_026558) Copy   

•   Source: SciCrunch Registry

https://www.skinresearch.northwestern.edu/cores/stem-core.html

Core provides services in human skin tissue procurement, isolation, and culture of human and murine skin-derived primary cells, 3D organotypic skin cultures, tissue processing, and basic histologic stains. The Core trains researchers in the development and use of these various techniques.

Proper citation: Northwestern University School of Medicine SBDRC Skin Tissue Engineering and Morphology Core Facility (RRID:SCR_026414) Copy   

•   Source: SciCrunch Registry

http://biomicro.mit.edu

Integrated genomics/bioinformatics facility located at MIT. Provides Illumina HiSeq2000, NextSeq500 and MiSeq sequencing instruments as well as PacBio Sequel and Oxford Minion. Provides services in preparing Illumina libraries for high-throughput sequencing samples using several different methods, supports technologies including Agilent BioAnalyzer, AATI Fragment Analyzer, AATI FemtoPulse, Roche LC480 qPCR machines, automated liquid handling through Tecan Evo150s, TTP Labtech Mosquito HV. Supports 10X Chromium and single cell work using NamoCell single cell dispenser and custom oligo synthesis using Dr.Oligo 192. Supports informatics and bioIT tools. Core administers ~2PB of data storage on several platforms, including 600TB Isilon server. Hosts 400 processor Dell cluster and Dell Quad Core 2950 application server for Illumina sequencing and bioinformatic applications. All application servers and storage servers are interconnected by 1gigabyte private networks or by fiber optic lines and are administered by IT staff that are part of the BioMicro Center. Servers are configurable to provide secure data storage for clinical data if required.

Proper citation: Massachusetts Institute of Technology MIT BioMicro Center Core Facility (RRID:SCR_026413) Copy   

•   Source: SciCrunch Registry

https://aiml.rockefeller.edu/

Data Science Platform focuses on Artificial Intelligence, Signal Processing, Computer Vision with the aim of advancing the research of Rockefeller Laboratories. DSP owns and operates fully dedicated computing infrastructure, equipped with state of the art GPUs and large storage capabilities.

Proper citation: Rockefeller University Data Science Platform Core Facility (RRID:SCR_026546) Copy   

•   Source: SciCrunch Registry

http://www.cas.miamioh.edu/cbfg/

Core provides training and equipment. Instruments include Pacific Biosciences VEGA benchtop long-read system, Oxford Nanopore Technologies minION and an Illumina MiSeq Next Generation Sequencing instrumentation, ABI Capillary Electrophoresis Genetic Analyzer (3130xl); an Eppendorf epMotion 5073m NGS liquid handling workstation; Promega MaxwellRSC Nucleic Acid extraction robot; real-time qPCR instruments (Rotor-Gene Q with HRM, Bio-Rad CFX Connect, QuantStudio 7 Flex [384/96 well interchangeable blocks]), and Bio-Rad ddPCR QX200 system, laser Attune NxT Flow Cytometer for analysis, laser BD FACS Melody Flow Cytometer for sorting, UV NanoDrop spectro photometers (ND1000, ND2200), and NanoDrop (ND3300) Fluorospectrophotometer; Promega Quantus, Agilent Bioanalyzer 2100; Covaris M220 Ultrasonic Nucleic Acid Shearer, a Sage BluePippin, seven 96 well gradient capable PCR thermal cyclers, two thermally controlled table top centrifuges capable of accepting 96-well plates used for DNA template preparation; two Eppendorf ThermoMixer C mixing units (384 well PCR to 50 mL tube format), two benchtop micro-centrifuges, Molecular Devices SpectraMax iD5 microplate reader, KTA-FPLC with UV detector and fractions collector, UV-1600PC UV-VIS Spectrophotometer with Sipper module, AlphaInnotechHP Gel Imaging System, Bio-Rad ChemiDoc MP Imaging System, Bio-Rad Dodeca-Cell Criterion PAGE system, several Bio-Rad Mini-Protean Gel Apparatus, Bio-Rad IEF Focusing Cells; numerous power-packs for gel electrophoresis, DNA gel boxes, pipettors, multi-channel pipettors. Provides computers (Linux & Win10), including four Ubuntu O/S based workstations for genome assembly and related bioinformatics analyses. CBFG maintains paid licenses for CLC Genomics Workbench, CLC Main Workbench, BioBam OmicsBox, SnapGene, FlowJo 10, SoftMax 7.1, Biogazelle qBasePLUS, and CANOCO.

Proper citation: Miami University Center for Bioinformatics and Functional Genomics Core Facility (RRID:SCR_026415) Copy   

•   Source: SciCrunch Registry

https://enprc.emory.edu/nhp_genomics_core/index.html

Core offers assistance in experimental design, sample preparation, library prep, sequencing, data analysis and bioinformatics. Provides experience working with non-human primate genomes and other non-standard genomes in addition to the more commonly studied human and mouse genomes. Provides expertise in the use of transcriptomics and genomics to study immune responses and repertoires.Houses Illumina NovaSeq 6000 and Illumina MiSeq.

Proper citation: Emory University EPC Genomics Core Facility (RRID:SCR_026418) Copy   

•   Source: SciCrunch Registry

https://www.skinresearch.northwestern.edu/cores/get-in-core.html

Core provides services and R&D in cell engineering and gene expression modifications by using retro- and lentivirus, adenovirus, adeno-associated virus, shRNA/MIR and CRISPR-Cas9 genome editing methods.

Proper citation: Northwestern University School of Medicine SBDRC Gene Editing, Transduction and Nanotechnology Core Facility (RRID:SCR_026417) Copy   

•   Source: SciCrunch Registry

https://www.skinresearch.northwestern.edu/cores/test-it-core.html

Core provides service, equipment, protocols, and training to help investigators differentiate healthy skin from skin with abnormal immune responses at the cellular and molecular level, to enable biomarker identification as well as to increasing our knowledge of skin immune responses.

Proper citation: Northwestern University School of Medicine SBDRC Translating Experimental Skin Testing with Immune Tracing, Informatics, and Technology Core Facility (RRID:SCR_026419) Copy   

•   Source: SciCrunch Registry

https://www.bidmc.org/research/core-facilities/preclinical-murine-pharmacogenetics-core

Core provides expertise in the design and implementation of preclinical trials to test new drugs, drug combinations and novel therapeutic modalities in mouse models of human diseases.

Proper citation: Beth Israel Deaconess Medical Center Preclinical Murine Pharmacogenetics Core Facility (RRID:SCR_026599) Copy   

•   Source: SciCrunch Registry

http://www.cores.emory.edu/aiec/

Core is supported by the Emory University School of Medicine. Enables large-scale, secure image extraction and de-identification to empower clinical, translational, and AI research.

Proper citation: Emory University AI Image Extraction Core Facility (RRID:SCR_026693) Copy   

•   Source: SciCrunch Registry

https://medresearch.umich.edu/office-research/about-office-research/biomedical-research-core-facilities/flow-cytometry-core

Flow Cytometry Core provides instrumentation, expertise and services. Samples are prepared by individual investigators, who then deliver to the Core for flow cytometric analysis or cell sorting. The Core also provides assistance in grant and publication preparation, publication-quality graphics, and the development of experimental designs.

Proper citation: University of Michigan Medical School BRCF Flow Cytometry Core Facility (RRID:SCR_026697) Copy   

•   Source: SciCrunch Registry

https://web.natur.cuni.cz/sekce-bi/VMCF/

Facility is equipped with range of advanced microscopes, from traditional light microscopes to cutting-edge super-resolution and live cell imaging systems.Provides imaging and analysis services.

Proper citation: Charles University Vinicna Microscopy Core Facility (RRID:SCR_026602) Copy   

•   Source: SciCrunch Registry

https://rna.umich.edu/research/cores/bru-seq-lab/

Core facility provides nascent RNA sequencing using four techniques: Bru-seq, BruChase-seq, BruUV-seq, and BruDRB-seq. This service is all-inclusive, starting with cells and ending with basic data analysis. In addition, users will have access to our exclusive pipeline to perform further data analysis. Our areas of expertise are RNA isolation, cDNA library preparation, and sequencing data analysis.

Proper citation: University of Michigan Bru-Seq Lab Core Facility (RRID:SCR_026726) Copy   

•   Source: SciCrunch Registry

https://www.bcchr.ca/histologycore

Core is a multi-user facility located on the 4th floor in the Translational Research Building (TRB) at A4-132. Histology facility offers services for processing tissue samples, automated equipment for tissue processing, paraffin embedding, micro-sectioning, and staining. Our technicians offer consultation, experimental design, and troubleshooting and work closely with researchers to get the most optimal tissue sections tailored to each project. The facility also provides training on the microtome and paraffin embedder to allow flexibility in workflow.

Proper citation: University of British Columbia BCCHR Histology Core Facility (RRID:SCR_026604) Copy   

•   Source: SciCrunch Registry

https://sites.google.com/umich.edu/cardio-regen-corelab/home?authuser=0&pli=1

Core routinely generates patient-specific human induced pluripotent stem cells (hiPSCs) for basic science research purposes. Focus is on cardiovascular cell differentiation of hiPSCs to generate unlimited supplies of patient specific cardiovascular cells for in vitro research. Basic services include:hiPSC derivation, hiPSC characterization, hiPSC expanstion;hiPSC differentiation to: Cardiomyocytes, Endothelial Cells, Vascular Smooth Muscle Cells, Pancreatic Cells;3D organoids: Cardiac, Pancreatic;Cardiotoxicity Screening-Drug Discovery Projects;Arrhythmia Testing;High Content Time Lapse Imaging.

Proper citation: University of Michigan Cardiovascular Regeneration Core Facility (RRID:SCR_026728) Copy   

•   Source: SciCrunch Registry