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https://case.edu/medicine/cddrcc/cores/

Collection of four cores: the biorepository core, for clinical specimen storage; the Histology/Imaging Core, for tissue preparation and sectioning; the Mouse Models Core, for education and training on various mouse modeling techniques; and the Clinical Component of the Administrative Core, for clinical study design consultation.

Proper citation: Cleveland Digestive Diseases Research Core Facilities (RRID:SCR_015216) Copy   

•   Source: SciCrunch Registry

https://www.bcm.edu/research/centers/digestive-disease/core-facilities/functional-genomics-and-microbiome

Core whose services include consultation in the choice of genomics methodologies to be applied to research problems being addressed by Digestive Diseases Center members, training in the conduct of functional genomics and metagenomics relevant to GI research, providing mammalian gene expression, cytokine/transcription factor/signaling pathway arrays, and gut microbial profiling/metagenomics to DDC members at discounted prices, and conducting periodic workshops and disseminating information about new technologies available in the Core and to obtain feedback on needed technologies / services.

Proper citation: Texas Medical Center Digestive Diseases Center Functional Genomics and Microbiome (RRID:SCR_015214) Copy   

•   Source: SciCrunch Registry

http://diabetesresearch.med.umich.edu/Core_MCDTR_Intervention.php

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Core that provides assistance to the Michigan Center for Diabetes Translational Research. Its three main services are consultation on content development and technologies, consultation about evidence for translatable diabetes interventions, and providing access to patient-centered health platforms.

Proper citation: Michigan Center for Diabetes Translational Research Intervention and Technology Research Core (RRID:SCR_015170) Copy   

•   Source: SciCrunch Registry

http://diabetesresearchcenter.dom.wustl.edu/immunology-of-type-1-diabetes-core/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core facility that provides logistic support to investigators examining autoimmune or type 1 diabetes mellitus (T1DM) or other endocrine autoimmunities. Its main purpose is to foster fundamental studies on T1DM through support for acquisition and use of diabetogenic strains of mice, islet isolation, and distribution of cells and antibodies relevant for immunological studies of T1DM.

Proper citation: Washington University School of Medicine Diabetes Research Center Immunology of Type 1 Diabetes Core (RRID:SCR_015143) Copy   

•   Source: SciCrunch Registry

http://diabetesresearchcenter.dom.wustl.edu/cell-and-tissue-imaging-core/

Core facility which provides researchers access to and technological support for advanced cellular microscopy and tools.

Proper citation: Washington University School of Medicine Diabetes Research Center Cell and Tissue Imaging Core (RRID:SCR_015140) Copy   

•   Source: SciCrunch Registry

https://www.vumc.org/vdrc/cores-hmpg

Core facility that provides a range of animal model systems to investigators working in the areas of diabetes and metabolism. It also offers surgical and experimental services, with limited analytical capacity in blood glucose and serology. The Human Metabolic Physiology and Genomics Core evolved from the Metabolic Physiology Shared Resource.

Proper citation: Vanderbilt Diabetes Research and Training Center Metabolic Physiology Shared Resource (RRID:SCR_015150) Copy   

•   Source: SciCrunch Registry

http://www.ucdenver.edu/academics/colleges/PublicHealth/research/centers/CAIANH/cdtr/Pages/National-Resource-Core.aspx

Purpose is to assemble, focus, mobilize, provide, monitor, and evaluate resources necessary to stimulate, carry out, and translate the outcomes of diabetes prevention and management research.

Proper citation: Center for American Indian and Alaska Native Diabetes Translational Research National Resource (RRID:SCR_015151) Copy   

•   Source: SciCrunch Registry

https://diabetes.med.umich.edu/affiliated-centers/michigan-diabetes-research-center-mdrc/cores/molecular-genetics

Core that provides services related to the application of genetic methodologies to research related to diabetes. Services include generation of targeted genetic mouse models, using CRISPR/Cas9 system in mouse or rat embryos, generation of specialty viral vectors, specialty viral reagents, and specialty mouse models.

Proper citation: Michigan Diabetes Research Center Molecular Genetics Core Facility (RRID:SCR_015119) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/idom/drc/cores/fgc.html

Core which offers experiment planning, sample preparation, quality assessment, library construction, DNA sequencing, and data analysis services to DRC members. Its services also include RNAseq, microRNAseq, GroSeq, CLIP-seq, nucleosome mapping, ATAC-Seq, ChIPseq, Exome sequencing, whole genome and targeted methylome analysis, hydroxymethyl DIP, and single cell RNAseq.

Proper citation: Penn Diabetes Research Center Functional Genomics Core (RRID:SCR_015121) Copy   

•   Source: SciCrunch Registry

https://joslinresearch.org/drc-cores/Induced-Pluripotent-Stem-Cell-Core

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 6,2024. Core that maintains a centralized facility for the generation and propagation of reprogrammed iPS cells for use in molecular and cellular pathologies underlying diabetes and its complications.

Proper citation: Joslin Diabetes Center Induced Pluripotent Stem Cell Core (RRID:SCR_015120) Copy   

•   Source: SciCrunch Registry

http://drtc.bsd.uchicago.edu/islet-cell-biology-core-about/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on November 7,2024. Core which provides services and hands-on training in the isolation and functional characterization of pancreatic islets from normal and diabetic humans and mice. It also maintains a repository of insulinoma cell lines for distribution. It puts emphasis on facilitating studies of primary islet cells and it has developed many unique tools and techniques for carrying such studies including novel animals models, biophysical methods and a library of adenovirus-based expression constructs for studying beta-cell function.

Proper citation: University of Chicago Diabetes Research and Training Center Islet Cell Biology Core (RRID:SCR_015132) Copy   

•   Source: SciCrunch Registry

https://diabetes.med.umich.edu/partners/michigan-diabetes-research-center-mdrc/cores/clinical

Clinical Core of the Michigan Diabetes Research Center (MDRC) provides expertise and services to support basic biomedical research, research focused on the translation of basic science findings into early phase clinical trials, and the testing of treatments related to diabetes in human subjects.

Proper citation: Michigan Diabetes Research Center Clinical Core Facility (RRID:SCR_015139) Copy   

•   Source: SciCrunch Registry

https://diabetescenters.org/cores/ucsd-ucla-genomics-and-epigenetics-core

Core which provides Diabetes Research Center investigators access to high-throughput sequencing, data acquisition and analysis. Its main services include Sample QC and Processing, Illumina Platform Library Preparation and Sequencing, and Expression microarrays (RNA, microRNA).

Proper citation: University of California San Diego - University of California Los Angeles Diabetes Research Center Genomics and Epigenetics Core Facility (RRID:SCR_015097) Copy   

•   Source: SciCrunch Registry

https://www.iths.org/resources/directory/listing/drc-quantitative-and-functional-proteomics-core-university-of-washington

Core facility that provides the powerful tools of modern mass spectrometry and complex data set analysis to Diabetes Research Center investigators to permit structural identification and quantitation of proteins involved in diabetes and its complications.

Proper citation: University of Washington Diabetes Research Center Quantitative and Functional Proteomics Core Facility (RRID:SCR_015131) Copy   

•   Source: SciCrunch Registry

http://cihd.cores.utah.edu/mgd/

Core facility which provides custom TALEN and Crispr-Cas9 DNA nucleases to induce targeted mutations in a genomic region of interest. It also provides hardware, reagents, and expertise for optimizing and performing HRMA for genes of interest.

Proper citation: Center for Iron and Heme Disorders at the University of Utah Mutation Generation and Detection Core (RRID:SCR_015339) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/csibd/cores/clinical.aspx

Core whose objective is to provide an infrastructure that facilitates the translation of basic research findings into the clinic. Its services include consultation, training, and education, biospecimen services, and facilitating data collection and analysis.

Proper citation: Center for the Study of Inflammatory Bowel Disease Clinical Core (RRID:SCR_015227) Copy   

•   Source: SciCrunch Registry

http://www.cancer.iu.edu/research-trials/facilities/angiobiocore/index.shtml

Core facility which conducts validated and reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders.

Proper citation: Indiana University Cooperative Center of Excellence in Hematology Angiogenesis Core (RRID:SCR_015345) Copy   

•   Source: SciCrunch Registry

http://www.massgeneral.org/csibd/cores/morphology.aspx

Core that provides CSIBD investigators with the technical support, expertise and access to instrumentation necessary for their morphological and cell biological studies related to IBD. These services include routine tissue fixation and processing for light microscopy, imaging flow cytometry, perfusion-fixation of organs, conventional electron microscopy, low temperature embedding in Lowicryl HM20, and immunocytochemistry.

Proper citation: Center for the Study of Inflammatory Bowel Disease Morphology Core (RRID:SCR_015228) Copy   

•   Source: SciCrunch Registry

http://medicine.yale.edu/labmed/ycceh/cores/core_d/index.aspx

Core facility which provides expertise, technical assistance, and mice for human-into-mouse xenotransplantation studies. Mouse models include MITRG-SKI (KnockIn) mice that express human cytokines and huSIRPa from the endogenous murine loci in the Rag-/- IL-2Ry -/- background. It also offers training and technical assistance in the study of hematopoiesis and benign hematologic questions in mice.

Proper citation: Yale Cooperative Center of Excellence in Hematology Animal Modeling Core (RRID:SCR_015349) Copy   

•   Source: SciCrunch Registry

http://www.mayo.edu/research/centers-programs/center-cell-signaling-gastroenterology-c-sig/cores-services/clinical-core

Core facility which supports faculty research by facilitating access to human biospecimens. Its services include centralized access to participating Mayo Clinic GI biobanks and other institutional biospecimen resources, de-identified, phenotypic and demographic data, and coordination of fresh tissue acquisition from surgical pathology.

Proper citation: Mayo Clinic Center for Cell Signaling in Gastroenterology Clinical Core (RRID:SCR_015229) Copy   

•   Source: SciCrunch Registry