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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.med.unc.edu/marsicolunginstitute/core-facilities/histology-core
Core that provides light microscopy services like prosection, tissue fixation, processing, embedding, sectioning, staining and cover slipping of paraffin, frozen and soft plastic tissue sections, as well as specialized and routine fixation, tissues processing, ultramicrotomy, staining, photomicrograph production, and analysis.
Proper citation: Cystic Fibrosis and Pulmonary Diseases Research and Treatment Center Histology Core (RRID:SCR_015385) Copy
http://bnorc.org/cores/fgb.html
Core provides services to investigators within BNORC and the Boston area looking to expand their research using state-of-the-art genomic applications. This core utilizes technologies and sequencing platforms to help identify the complex molecular mechanisms underlying human disease.
Proper citation: Boston Nutrition and Obesity Research Centers Functional Genomics and Bioinformatics Core (RRID:SCR_015423) Copy
http://www.norch.org/metabolic-phenotyping-core/
Core that provides NORCH investigators with access to model creation and detailed metabolic phenotyping. Its services include: model generation, including genomic targeting and production of metabolically relevant cell types; metabolic characterization of patient-derived, user-provided, or model generated samples; consultation on model development and metabolic characterization projects; and training for Core techniques in model generation and detailed metabolic characterization.
Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Phenotyping Core (RRID:SCR_015429) Copy
http://www.norch.org/metabolic-imaging-core/
Core that links a variety of imaging facilities providing services to NORCH investigators who currently require or plan to conduct human studies using imaging research instrumentation and expertise. Its goal is to provide users with access to imaging technology for in-vivo phenotyping of human tissues for nutrition, obesity and metabolism studies.
Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Imaging Core (RRID:SCR_015426) Copy
http://www.uab.edu/medicine/hrfdcc/cores
Core whose goals are to establish a national resource for clinical data, DNA, and tissue biopsies from human patients with HRFDs, develop algorithms to identify causative genetic mutations in HRFD patients and utilize a suite of new tools to assess the pathogenicity of sequence variants, and expand the portfolio of educational information and tools to encompass the HRFD spectrum of disorders.
Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Hepato-Renal Fibrocystic Diseases Translational Resource (RRID:SCR_015309) Copy
https://www.uab.edu/medicine/cysticfibrosis/about/translational-core
Core that provides human primary nasal airway epithelial cells and bronchial airway epithelial cells, expertise in the nasal potential difference measurement, and a means to understand pathogenesis of cystic fibrosis and other metabolic diseases.
Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Clinical and Translational Core (RRID:SCR_015399) Copy
http://www.uab.edu/medicine/hrfdcc/cores/d
Core goals include to develop in vitro predictive assays to identify and characterize HRFD lead compounds, develop in vivo predictive translational HRFD models to enhance efficacy assessment in preclinical testing, and develop advanced HRFD-specific toxicology and safety screens.
Proper citation: UAB Hepatorenal Fibrocystic Diseases Core Center Therapeutic Screening and Drug Development Resource (RRID:SCR_015314) Copy
https://nyonrc.cumc.columbia.edu/content/molecular-biologymolecular-genetics-core
Core whose goal is to assist investigators in applying the tools and technologies of molecular genetics and genomics to elucidate the molecular-genetic bases of obesity and its comorbidities. Its services include consultation on study design, analysis, and applicable molecular biological techniques and developing and making research tools and reagents.
Proper citation: New York Obesity Nutrition Research Center Molecular Biology and Molecular Genetics Core (RRID:SCR_015436) Copy
http://depts.washington.edu/cfrtc/genomics/
Core provides genomics-based tools, data management and analysis tools, and creates platforms that integrate data from the Clinical and Immunology Cores for human samples and bacterial isolates. Services include consultation and experimental design assistance for using new-generation sequencing technology, data analysis, bioinformatic support, data access and storage, high throughput and new-generation whole-genome sequencing, and RNA-seq analysis of transcriptomes.
Proper citation: University of Washington Genomics Core Cystic Fibrosis Research Translation Center and Research Development Program (RRID:SCR_015404) Copy
http://www.med.upenn.edu/gtp/immunology.shtml
Core facility which provides a variety of assay services to evaluate cell-mediated and humoral responses to in animal models of gene therapies.
Proper citation: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Immunology Core (RRID:SCR_015409) Copy
https://medicine.uiowa.edu/genetherapy/research-cores/cells-and-tissue-core
Core that provides centralized access to non-cystic fibrosis and cystic fibrosis tissue specimens and airway cells used for model systems to assess gene transfer to the airway and pathophysiology in cystic fibrosis.
Proper citation: University of Iowa Center for Gene Therapy Cell Tissue Core (RRID:SCR_015410) Copy
http://www.med.unc.edu/cgibd/cores/biostatistics
Core facility that provides comprehensive statistical and data management services. Its statistical analysis services include study design, power and sample size analysis, randomization, statistical programming, consultation and the development of analysis plans, graphs, figures and reports.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Biostatistics and Data Management Core (RRID:SCR_015616) Copy
http://www.med.unc.edu/cgibd/cores/histology
Core facility that provides a full range of histology services, encompassing routine and specialized grossing, tissue processing, paraffin embedding, microtomy, H&E and special staining, and immunohistochemistry. It also offers image analysis and consultations to CGIBD members and non-members.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Histology Core (RRID:SCR_015614) Copy
http://www.med.upenn.edu/molecular/core_morphology.shtml
Core facility that provides histological services, equipment usage, and technical expertise to digestive and liver research projects.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Molecular Pathology and Imaging Core (RRID:SCR_015618) Copy
http://www.med.upenn.edu/molecular/core_molecular.shtml
Core facility that provides services that will enhance the analysis of both host and microbial biological processes as well as facilitate translation into the clinical arena via human subject research.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Host-Microbial Analytic and Repository Core (RRID:SCR_015620) Copy
https://hddc.hms.harvard.edu/epithelial-cell-and-mucosal-immunology
Core facility that provides the infrastructure, biologic resources, expertise, and training for cross-disciplinary research on epithelial biology and immune function in mucosal surfaces and solid organs of the GI tract.
Proper citation: Harvard Digestive Diseases Center Biomedical CORE C: Epithelial Cell and Mucosal Immunology (RRID:SCR_015588) Copy
Core that uses technologies to facilitate the translation of traditional evidence-based behavioral interventions into effective web- and mobile-based interventions in fields such as obesity and cancer prevention.
Proper citation: University of North Carolina at Chapel Hill Nutrition and Obesity Research Center Communication for Health Applications and Interventions Core (RRID:SCR_015461) Copy
http://livercenter.ucsf.edu/immunology-core
Core that takes advantage of local expertise and resources to enable Center members to analyze cell populations in mouse or human livers. It performs complex analyses on small numbers of human cells, such as those obtained from liver biopsies.
Proper citation: UCSF Liver Center Immunology Core (RRID:SCR_015596) Copy
http://livercenter.ucsf.edu/clinical-translational-core
Core that supports study design to sample procurement and storage, to data analysis and presentation, and also focuses on research involving human subjects.
Proper citation: UCSF Liver Center Clinical & Translational Core (RRID:SCR_015598) Copy
http://livercenter.ucsf.edu/pathology-imaging-core
Core that provides services from routine liver histology to complex microscopy and image analysis.
Proper citation: UCSF Liver Center Pathology & Imaging Core (RRID:SCR_015599) Copy
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