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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
LONI Visualization Tool
 
Resource Report
Resource Website
LONI Visualization Tool (RRID:SCR_000765) LONI Viz, LONI_Viz, LOVE software resource, data visualization software, software application, data processing software A versatile 1D, 2D and 3D data viewer geared for cross-platform visualization of stereotactic brain data. It is a 3-D viewer that allows volumetric data display and manipulation of axial, sagittal and coronal views. It reads Analyze, Raw-binary and NetCDF volumetric data, as well as, Multi-Contour Files (MCF), LWO/LWS surfaces, atlas hierarchical brain-region labelings ( Brain Trees). It is a portable Java-based software, which only requires a Java interpreter and a 64 MB of RAM memory to run on any computer architecture. LONI_Viz allows the user to interactively overlay and browse through several data volumes, zoom in and out in the axial, sagittal and coronal views, and reports the intensities and the stereo-tactic voxel and world coordinates of the data. Expert users can use LONI_Viz to delineate structures of interest, e.g., sulcal curves, on the 3 cardinal projections of the data. These curves then may be use to reconstruct surfaces representing the topological boundaries of cortical and sub-cortical regions of interest. The 3D features of the package include a SurfaceViewer and a full real-time VolumeRenderer. These allow the user to view the relative positions of different anatomical or functional regions which are not co-planar in any of the axial, sagittal or coronal 2D projection planes. The interactive part of LONI_Viz features a region drawing module used for manual delineation of regions of interest. A series of 2D contours describing the boundary of a region in projection planes (axial, sagittal or coronal) could be used to reconstruct the surface-representation of the 3D outer shell of the region. The latter could then be resliced in directions complementary to the drawing-direction and these complementary contours could be loaded in all tree cardinal views. In addition the surface object could be displayed using the SurfaceViewer. A pre-loading data crop and sub-sampling module allows the user to load and view practically data of any size. This is especially important when viewing cryotome, histological or stained data-sets which may reach 1GB (109 bytes) in size. The user could overlay several pre-registered volumes, change intensity colors and ranges and the inter-volume opacities to visually inspect similarities and differences between the different subjects/modalities. Several image-processing aids provide histogram plotting, image-smoothing, etc. Specific Features: * Region description DataBase * Moleculo-genetic database * Brain anatomical data viewer * BrainMapper tool * Surface (LightWave objects/scenes) and Volume rendering tools * Interactive Contour Drawing tool Implementation Issues: * Applet vs. Application - the software is available as both an applet and a standalone application. The former could be used to browse data from within the LONI database, however, it imposes restrictions on file-size, Internet connection and network-bandwidth and client/server file access. The later requires a local install and configuration of the LONI_Viz software * Extendable object-oriented code (Java), computer architecture independent * Complete online software documentation is available at http://www.loni.ucla.edu/LONI_Viz and a Java-Class documentation is available at http://www.loni.ucla.edu/~dinov/LONI_Vis.dir/doc/LONI_Viz_Java_Docs.html brain, atlas, visualization, gene mapping, atlas application, magnetic resonance, surface analysis is listed by: NeuroImaging Tools and Resources Collaboratory (NITRC)
is listed by: Biositemaps
has parent organization: Laboratory of Neuro Imaging
Aging NIA P50 AG16570;
NLM 2R01 LM05639-06;
NIA K08 AG100784;
NCRR 2 P41 RR13642;
NIMH 5 P01 MN52176;
NSF DUE 0442992;
NCRR U52 RR021813
PMID:16598642 Free, Available for download, Freely available nif-0000-23313 http://www.nitrc.org/projects/incf_loni-viz http://www.loni.ucla.edu/Software/LOVE SCR_000765 LONI Visualization Environment, LONI Viz environment, LOVE 2026-08-03 09:31:08 0
GlimmerHMM
 
Resource Report
Resource Website
500+ mentions
GlimmerHMM (RRID:SCR_002654) GlimmerHMM software resource, source code A gene finder based on a Generalized Hidden Markov Model (GHMM). Although the gene finder conforms to the overall mathematical framework of a GHMM, additionally it incorporates splice site models adapted from the GeneSplicer program and a decision tree adapted from GlimmerM. It also utilizes Interpolated Markov Models for the coding and noncoding models . Currently, GlimmerHMM's GHMM structure includes introns of each phase, intergenic regions, and four types of exons (initial, internal, final, and single). gene, hidden markov model is related to: Glimmer
has parent organization: Johns Hopkins University; Maryland; USA
NIH ;
NLM R01-LM06845;
NLM R01-LM007938
PMID:15145805 Free, Available for download, Freely available nlx_156092 SCR_002654 GlimmerHMM - Eukaryotic Gene-Finding System 2026-08-03 09:32:04 576
The NINDS Human Cell and Data Repository (NHCDR)
 
Resource Report
Resource Website
10+ mentions
The NINDS Human Cell and Data Repository (NHCDR) (RRID:SCR_016319) NHCDR tissue bank, biomaterial supply resource, material resource Cell sources currently include fibroblasts and/or induced pluripotent stem cells for Alzheimer's Disease, Amyotrophic Lateral Sclerosis (ALS), Ataxia-telangiectasia, Frontotemporal Lobar Degeneration (FTD), Huntington's Disease, Parkinson's Disease, and healthy controls. Cell sources, including isogenic cell lines for current and new diseases covered by the NINDS will be added over the next several years. Stem, cell, fibroblast, plutipotent, isogenic is used by: NIH Heal Project
is recommended by: National Library of Medicine
is listed by: re3data.org
works with: Cellosaurus
Alzheimer's Disease, Amyotrophic Lateral Sclerosis (ALS), Ataxia-telangiectasia, Frontotemporal Lobar Degeneration (FTD), Huntington's Disease, Parkinson's Disease NLM ;
NINDS
Restricted https://nindsgenetics.org/ SCR_016319 NINDS Human Cell and Data Repository (NHCDR) 2026-08-03 09:36:22 16
Midas Platform
 
Resource Report
Resource Website
10+ mentions
Midas Platform (RRID:SCR_002186) Midas data management software, software toolkit, software resource, software application Open-source toolkit that enables the rapid creation of tailored, web-enabled data storage and provides a cohesive system for data management, visualization, and processing. At its core, Midas Platform is implemented as a PHP modular framework with a backend database (PostGreSQL, MySQL and non-relational databases). While the Midas Platform system can be installed and deployed without any customization, the framework has been designed with customization in mind. As building one system to fit all is not optimal, the framework has been extended to support plugins and layouts. Through integration with a range of other open-source toolkits, applications, or internal proprietary workflows, Midas Platform offers a solid foundation to meet the needs of data-centric computing. Midas Platform provides a variety of data access methods, including web, file system and DICOM server interfaces, and facilitates extending the methods in which data is stored to other relational and non-relational databases. data storage, data analysis, visualization, multimedia, digital archiving, processing has parent organization: Kitware NLM ;
NIH ;
NCI
PMID:18560078 Apache License, v2, Simplified BSD License, BSD License nlx_154696 SCR_002186 Midas Platform - The Multimedia Digital Archiving System 2026-08-03 09:31:47 42
MEDI
 
Resource Report
Resource Website
100+ mentions
MEDI (RRID:SCR_015668) software resource, software application, standalone software Medication indication software for primary and secondary uses of electronic medical record (EMR) data. MEDI was created based on multiple commonly used medication resources (RxNorm, MedlinePlus, SIDER 2, and Wikipedia ) and by leveraging both ontology and natural language processing (NLP) techniques. ensemble medication indication, electronic medical record, emr NLM 1 R01 LM 010685 PMID:23576672 Free, Available for download SCR_015668 MEDI (MEDication Indication), MEDication Indication, MEDI--an Ensemble MEDication Indication Resource 2026-08-03 09:36:04 215
MetaMap
 
Resource Report
Resource Website
100+ mentions
MetaMap (RRID:SCR_015031) text-mining software, software resource, software application Program to map biomedical text to the UMLS Metathesaurus and to discover Metathesaurus concepts referred to in text based on symbolic, natural-language processing and computational-linguistic techniques. text mining, biomedical text NLM Free, Account required SCR_015031 MetaMap 2016, MetaMap 2016v2 2026-08-03 09:35:43 337
Gene Atlas
 
Resource Report
Resource Website
10+ mentions
Gene Atlas (RRID:SCR_008089) Geneatlas data or information resource, atlas, database This website allows visitors to search for genes of interest based on their spatial expression patterns in the Postnatal Day 7 mouse brain. Geneatlas provides two searching tools: A graphical interface for customized spatial queries; A textual interface for querying annotated structures. Geneatlas is the product of a collaboration between researchers at Baylor College of Medicine, Rice University, and University of Houston. gene, brain, mouse, protein, spatial expression, molecular neuroanatomy resource, FASEB list has parent organization: University of Houston; Texas; USA
has parent organization: Baylor University; Texas; USA
Burroughs Wellcome Fund ;
NLM 5T15LM07093;
NCRR P41RR02250
nif-0000-10987 SCR_008089 2026-08-03 09:33:52 47
SHRINE
 
Resource Report
Resource Website
1+ mentions
SHRINE (RRID:SCR_006293) SHRINE software resource, source code, software application Software providing a scalable query and aggregation mechanism that enables federated queries across many independently operated patient databases. This platform enables clinical researchers to solve the problem of identifying sufficient numbers of patients to include in their studies by querying across distributed hospital electronic medical record systems. Through the use of a federated network protocol, SHRINE allows investigators to see limited data about patients meeting their study criteria without compromising patient privacy. This software should greatly enable population-based research, assessment of potential clinical trials cohorts, and hypothesis formation for followup study by combining the EHR assets across the hospital system. In order to obtain the maximum number of cases representing the study population, it is useful to aggregate patient facts across as many sites as possible. Cutting across institutional boundaries necessitates that each hospital IRB remain in control, and that their local authority is recognized for each and every request for patient data. The independence, ownership, and legal responsibilities of hospitals predetermines a decentralized technical approach, such as a federated query over locally controlled databases. The application comes with the SHRINE Core Ontology but it can be used with any ontology, even one that is disease specific. The Core Ontology is designed to enable the widest range of studies possible using facts gathered in the EMR during routine patient care. SHRINE allows multiple ontologies to be used for different research purposes on the same installed systems. software network, clinical database, data sharing, clinical, medical record, federated, platform, network is related to: i2b2 Cross-Institutional Clinical Translational Research project
is related to: i2b2 Research Data Warehouse
has parent organization: Harvard Medical School; Massachusetts; USA
Informatics for Integrating Biology and the Bedside ;
NLM 5 U54 LM008748;
NCRR 1 UL1 RR025758-01
PMID:19567788 Available under a BSD3 Open unspecified license Software license. nlx_151949 SCR_006293 Shared Health Research Informatics NEtwork 2026-08-03 09:33:02 8
tTFtarget
 
Resource Report
Resource Website
1+ mentions
tTFtarget (RRID:SCR_025631) data or information resource, database Transcription factor target database. Platform consolidating both computationally predicted and experimentally validated binding sites between transfer RNA-derived fragments and target genes or transcripts across multiple organisms. Transcription factor target, validated binding sites, transfer RNA-derived fragments, target genes, multiple organisms, NLM R01LM014087;
NSF
DOI:10.1093/nar/gkad815 Free, Freely available SCR_025631 tRFtarget 2.0, tRFtarget 1.0 2026-08-03 09:38:49 2
CDEMapper
 
Resource Report
Resource Website
CDEMapper (RRID:SCR_027602) software resource, software application, source code Software Common Data Elements (CDEs) mapping tool to bridge the gap between local data elements and National Institutes of Health (NIH) CDEs. Elasticsearch and Large Language Model (LLM)-powered mapping tool designed for biomedical and clinical researchers to efficiently map study variables to the NIH Common Data Elements (CDEs). It integrates essential and advanced services into a user-centered mapping workflow, allowing users to choose different mapping strategies based on their project's needs.Used for enhancing National Institutes of Health common data element use with large language models. mapping, map study variables, NIH Common Data Elements, map study variables to NIH Common Data Elements, NLM U24LM013755 PMID:40332956 Free, Available for download, Freely available https://github.com/BIDS-Xu-Lab/CDE-Mapping-Tool SCR_027602 CDEMapper 2.0 2026-08-03 09:39:13 0

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