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| Resource Name | Proper Citation | Abbreviations | Resource Type |
Description |
Keywords | Resource Relationships | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
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ea-utils Resource Report Resource Website 100+ mentions |
ea-utils (RRID:SCR_005553) | ea-utils | software resource | Command-line software tools for processing biological sequencing data. Barcode demultiplexing, adapter trimming, etc. Primarily written to support an Illumina based pipeline - but should work with any FASTQs. | bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools |
DOI:10.2174/1875036201307010001 | MIT License | OMICS_01041, biotools:ea-utils | https://bio.tools/ea-utils, https://sources.debian.org/src/ea-utils/ | SCR_005553 | ea-utils: FASTQ processing utilities | 2026-09-12 12:56:28 | 289 | |||||
|
BSeQC Resource Report Resource Website 1+ mentions |
BSeQC (RRID:SCR_005428) | BSeQC | software resource | A quality control software package specially for bisulfite sequencing experiments. It can comprehensively evaluate the quality of BS-seq experiments and automatically trim nucleotides with potential technical biases. In addition, BSeQC also support removing duplicate reads and keeping one copy of the overlapping segment in paired-end sequencing. | bisulfite sequencing, bisulfite, sequencing | is listed by: OMICtools | Artistic License, GNU General Public License | OMICS_00572 | SCR_005428 | BSeQC: Quality Control of bisulfite sequencing experiments | 2026-09-12 12:56:26 | 6 | |||||||
|
NGSQC Resource Report Resource Website 100+ mentions |
NGSQC (RRID:SCR_005459) | NGSQC | software resource | Software pipeline that provides a set of novel quality control measures for quickly detecting a wide variety of quality issues in deep sequencing data derived from two dimensional surfaces, regardless of the assay technology used. It also enables researchers to determine whether sequencing data related to their most interesting biological discoveries are caused by sequencing quality issues. NGSQC can help to ensure that biological conclusions, in particular those based on relatively rare sequences, are not caused by low quality sequencing., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. | next generation sequencing, quality control |
is listed by: OMICtools has parent organization: University of Michigan; Ann Arbor; USA |
PMID:21143816 | THIS RESOURCE IS NO LONGER IN SERVICE | OMICS_01064 | SCR_005459 | Next Generation Sequencing Quality Control, NGSQC: Next Generation Sequencing Quality Control | 2026-09-12 12:56:26 | 129 | ||||||
|
MSC Resource Report Resource Website |
MSC (RRID:SCR_005450) | MSC | software resource | A classification software for DNA methylation profiling with bisulphite next-generation sequencing data. | classification, dna methylation, bisulfite, next-generation sequencing, methylation, r | is listed by: OMICtools | PMID:24273245 | OMICS_00610 | SCR_005450 | Methylation Status Calling | 2026-09-12 12:56:26 | 0 | |||||||
|
MLML Resource Report Resource Website 1+ mentions |
MLML (RRID:SCR_005449) | MLML | software resource | A software tool to simultaneously estimate hydroxymethylation (5hmC) and methylation (5mC) levels from BS-seq, oxBS-seq and TAB-seq experiments. It generates consistent estimates across experiment types. |
is listed by: OMICtools has parent organization: University of Southern California; Los Angeles; USA |
OMICS_00609 | SCR_005449 | 2026-09-12 12:56:26 | 7 | ||||||||||
|
MethylExtract Resource Report Resource Website 10+ mentions |
MethylExtract (RRID:SCR_005446) | MethylExtract | software resource | A user friendly software tool to generate i) high quality, whole genome methylation maps and ii) to detect sequence variation within the same sample preparation. | bisulfite sequencing, methylation map, methylation, sequence variation, bio.tools |
is listed by: OMICtools is listed by: bio.tools is listed by: Debian has parent organization: University of Granada; Granada; Spain |
Acknowledgement requested | biotools:methylextract, OMICS_00605 | https://bio.tools/methylextract | SCR_005446 | High-Quality methylation maps and SNV calling from BS-Seq experiments | 2026-09-12 12:56:26 | 14 | ||||||
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CpG MPs Resource Report Resource Website |
CpG MPs (RRID:SCR_005441) | CpG_MPs | analysis service resource, data analysis service, production service resource, service resource, software resource | Tool for identification and analysis of CpG methylation patterns of genomic regions from high-throughput bisulfite sequencing data. It may identify the unmethylated and methylated regions for a single sample, the conserved and differential methylation regions with different methylation patterns for paired or multiple samples. It includes four main modules as follows: # Normalization of the sequencing reads of cytosines following guanines; # Identification of the unmethylated (methylated) regions using hotspot extension algorithm; # Identification of conservatively and differentially methylated regionsby combining the combinatorial algorithm for determination of potentially functional regions with the algorithm of analysis of variance (ANOVA) for assess the statistical significance of differentially methylated regions; # Extraction of sequence features and visualization of these potentially functional regions. | genomic methylation pattern, genomic, methylation pattern, java |
is listed by: OMICtools has parent organization: Harbin Medical University; Heilongjiang; China |
OMICS_00596 | SCR_005441 | CpG_MPs: identification of CpG methylation patterns of genomic regions | 2026-09-12 12:56:26 | 0 | ||||||||
|
GobyWeb Resource Report Resource Website 1+ mentions |
GobyWeb (RRID:SCR_005443) | GobyWeb | software resource | Web application that facilitates the management and analysis of high-throughput sequencing (HTS) data. In the back-end, it uses the Goby framework, BWA, STAR, Last, GSNAP, Samtools, VCF-tools, along with a cluster of servers to provide rapid alignment and efficient analyses. GobyWeb makes it possible to analyze hundreds of samples in consistent ways without having to use command line tools. GobyWeb provides tools that streamline frequent data analyses for RNA-Seq, Methyl-Seq, RRBS, or DNA-Seq datasets and to enable teams of investigators to share reads and results of analyses. GobyWeb can be extended for new analyses by developing plugins. | high-throughput sequencing, gene expression, dna methylation, sequencing, bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools has parent organization: Weill Cornell Medical College; New York; USA |
PMID:23936070 | Acknowledgement requested, GNU Lesser General Public License, v3 | OMICS_00601, biotools:gobyweb | https://bio.tools/gobyweb | SCR_005443 | 2026-09-12 12:56:26 | 3 | ||||||
|
Genetic Testing Registry Resource Report Resource Website 10+ mentions |
Genetic Testing Registry (RRID:SCR_005565) | GTR | data or information resource, data repository, database, service resource, storage service resource | Central location for voluntary submission of genetic test information by providers including the test''s purpose, methodology, validity, evidence of the test''s usefulness, and laboratory contacts and credentials. GTR aims to advance the public health and research into the genetic basis of health and disease. GTR is accepting registration of clinical tests for Mendelian disorders, complex tests and arrays, and pharmacogenetic tests. These tests may include multiple methods and may include multiple major method categories such as biochemical, cytogenetic, and molecular tests. GTR is not currently accepting registration of tests for somatic disorders, research tests or direct-to-consumer tests. | genetic, gene, clinical, genetic test, condition, phenotype, disease name, trait, drug, protein, analyte, disease, laboratory, molecular, clinical, genetics, people |
lists: MedGen is listed by: OMICtools has parent organization: NCBI |
The community can contribute to this resource | OMICS_01541, nlx_144654 | SCR_005565 | NIH Genetic Testing Registry, GTR: Genetic Testing Registry | 2026-09-12 12:56:28 | 36 | |||||||
|
QC-Chain Resource Report Resource Website 1+ mentions |
QC-Chain (RRID:SCR_005438) | QC-Chain | software resource | A software package of quality control tools for next generation sequencing (NGS) data, consisting of both raw reads quality evaluation and de novo contamination screening, which could identify all possible contamination sequences. This QC pipeline supplies a fast, easy-to-use, and parallel processing approach to accomplish the comprehensive QC steps, which could be applied widely to almost all kinds of NGS reads, including genomic, transcriptomic and metagenomic data. | next generation sequencing |
is listed by: OMICtools has parent organization: Chinese Academy of Sciences; Beijing; China |
OMICS_01070 | SCR_005438 | 2026-09-12 12:56:26 | 4 | |||||||||
|
PRIMEGENS Resource Report Resource Website 1+ mentions |
PRIMEGENS (RRID:SCR_005474) | PRIMEGENS | analysis service resource, data analysis service, production service resource, service resource, software resource | A Web-based Tool for High-throughput Primer and Probe Design. The program has its different utilities available on its web server. A standalone version is also available. Algorithms: * SSPD - Sequence Specific Primer Design: to design primers for each of the specific sequences given by the user in the query input file against any alternate potential hybridization with any of the sequences given in the database input file. * PSPD - Probe Specific Primer Design: to design primers it selects the gene-specific fragments (probes) to design primer pairs for their PCR amplification. * FSPD Fragment Specific Primer Design: primer design algorithm used when there is a very long query sequence for which multiple primers are required for its amplification. * Check Binding Specificity * Probe Design Only: Probe design algorithm could be used to find sequence-specific probes, which doesn''t show any blast hit against database. Such probe design has been used for targeted sequencing like agilent sure-select technology with next-generation sequencing. | primer design, high-throughput primer, probe, microarray, analysis, blast, hybridization, primer, probe design, dna methylation |
is listed by: OMICtools has parent organization: University of Missouri; Missouri; USA |
DOE ; DOD ; NIH |
PMID:21415011 PMID:18579568 PMID:17951795 PMID:12424113 |
Free for academic use, Commercial use requires license | OMICS_00637, OMICS_02346 | http://digbio.missouri.edu/primegens/ | SCR_005474 | PRIMEGENS-w3, PRIMEGENS - High-throughput Primer and Probe Design, PRIMEGENSw3 | 2026-09-12 12:56:26 | 3 | ||||
|
VDJ Resource Report Resource Website 1+ mentions |
VDJ (RRID:SCR_005475) | software resource | Python package for analysing immune receptor sequences (antibodies and T cell receptors). | standalone software, python | is listed by: OMICtools | PMID:24639495 | Apache License, v2 | OMICS_04064 | SCR_005475 | 2026-09-12 12:56:26 | 3 | ||||||||
|
Bowtie Resource Report Resource Website 10000+ mentions |
Bowtie (RRID:SCR_005476) | alignment software, data analysis software, data processing software, image analysis software, sequence analysis software, software application, software resource | Software ultrafast memory efficient tool for aligning sequencing reads. Bowtie is short read aligner. | sequence, analysis, long, reference, read, alignment, gap, local, pair, end, rna, rnaseq, bio.tools |
is used by: deFuse is used by: Short Read Sequence Typing for Bacterial Pathogens is used by: TopHat is used by: BS Seeker is listed by: OMICtools is listed by: bio.tools is listed by: Debian is listed by: SoftCite is related to: Bowtie 2 has parent organization: Johns Hopkins University; Maryland; USA is required by: RelocaTE |
Amazon Web Services in Education Research ; NHGRI R01 HG006102; NIGMS R01 GM083873 |
PMID:19261174 DOI:10.1186/gb-2009-10-3-r25 |
Free, Available for download, Freely available | biotools:bowtie, OMICS_00653 | https://github.com/BenLangmead/bowtie, https://bio.tools/bowtie, https://sources.debian.org/src/bowtie/ | SCR_005476 | 2026-09-12 12:56:26 | 13799 | ||||||
|
CASHX Resource Report Resource Website 1+ mentions |
CASHX (RRID:SCR_005477) | CASHX | software resource | Software pipeline to parse, map, quantify and manage large quantities of sequence data. CASHX is a set of tools that can be used together, or as independent modules on their own. The reference genome alignment tools can be used with any reference sequence in fasta format. The pipeline was designed and tested using Arabidopsis thaliana small RNA reads generated using an Illumina 1G. |
is listed by: OMICtools has parent organization: Oregon State University; Oregon; USA |
NSF MCB-1231726; NIAI AI43288 |
PMID:19307293 | OMICS_00655 | SCR_005477 | Cache ASsisted Hash Search with Xor logic Pipeline, CASHX Pipeline, Cache ASsisted Hash Search with Xor logic | 2026-09-12 12:56:26 | 4 | |||||||
|
TreQ Resource Report Resource Website |
TreQ (RRID:SCR_005505) | TreQ | software resource | A software read mapper for high-throughput DNA sequencing reads, in particular one to several hundred nucleotides in length, and for large edit distance between sequencing read and match in the reference genome. It can cope particularly well with indels for single-best hit recall of 200nt reads simulated from the human reference genome. TreQ performs best at a running time comparable to BWA at large edit distance settings. | bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools has parent organization: SourceForge has parent organization: Rutgers University; New Jersey; USA |
PMID:22962448 | GNU General Public License | OMICS_00695, biotools:treq | https://bio.tools/treq | SCR_005505 | TreQ: Indel-tolerant Read Mapper | 2026-09-12 12:56:27 | 0 | |||||
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DiProGB Resource Report Resource Website 1+ mentions |
DiProGB (RRID:SCR_005651) | DiProGB | software resource | Genome browser that encodes the genome sequence by physico-chemical dinucleotide properties such as stacking energy, melting temperature or twist angle. Analyses can be performed for the + and ?, as well as for the double strand. | genome, browser, bio.tools |
is listed by: OMICtools is listed by: bio.tools is listed by: Debian is related to: Dinucleotide Property Database |
PMID:19605418 | Free, Freely available | biotools:diprogb, OMICS_00880 | https://bio.tools/diprogb | SCR_005651 | DiProGB - The Dinucleotide Properties Genome Browser, Dinucleotide Properties Genome Browser | 2026-09-12 12:56:29 | 4 | |||||
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MagicViewer Resource Report Resource Website 10+ mentions |
MagicViewer (RRID:SCR_005648) | MagicViewer | software resource | Software to easily visualize the short reads alignment, identify the genetic variation and associate with the annotation information of reference genome. MagicViewer provides a user-friendly interface in which large-scale short reads and sequencing depth can be easily visualized in zoomable images under user definable color scheme through an operating system-independent manner with the implement of Java language. Meanwhile, it holds a versatile genetic variation annotation and visualization interface, providing details of the query options, functional classifications, subset selection, sequence association and primer design. | dna methylation, bisulfite sequencing |
is listed by: OMICtools has parent organization: Wenzhou Medical University; Zhejiang; China |
PMID:20444865 | Free, Public | OMICS_00887 | SCR_005648 | MagicViewer: Integrated Solution for Next-generation Sequencing Data Visualization and Genetic Variation Detection and Annotation | 2026-09-12 12:56:29 | 16 | ||||||
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Bambino Resource Report Resource Website 1+ mentions |
Bambino (RRID:SCR_005649) | Bambino | analysis service resource, data analysis service, production service resource, service resource, software resource | A variant detector and graphical alignment viewer for next-generation sequencing data in the SAM/BAM format, which is capable of pooling data from multiple source files. Bambino may be launched online via Java Web Start or downloaded and run locally. | java, next-generation sequencing, bio.tools |
is listed by: OMICtools is listed by: Debian is listed by: bio.tools has parent organization: National Cancer Institute |
PMID:21278191 | Https://cgwb.nci.nih.gov/goldenPath/bamview/documentation/Bambino_Click-thru-agreement-for-executable_final.txt | OMICS_00876, biotools:bambino | https://bio.tools/bambino | SCR_005649 | Bambino: a variant detector and alignment viewer for next-generation sequencing data in the SAM/BAM format | 2026-09-12 12:56:29 | 5 | |||||
|
WISECONDOR Resource Report Resource Website 10+ mentions |
WISECONDOR (RRID:SCR_005646) | WISECONDOR | software resource | A set of python scripts that detects fetal chromosomal and subchromosomal duplications and deletions in maternal blood samples., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. |
is listed by: OMICtools has parent organization: Netherlands Bioinformatics Centre |
THIS RESOURCE IS NO LONGER IN SERVICE | OMICS_00354 | SCR_005646 | WIthin-SamplE COpy Number aberration DetectOR | 2026-09-12 12:56:29 | 12 | ||||||||
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BS Seeker Resource Report Resource Website 1+ mentions |
BS Seeker (RRID:SCR_005641) | data analysis software, data processing software, sequence analysis software, software application, software resource | Software which performs accurate and fast mapping of bisulfite-treated short reads. Supplementary information and examples are provided on the site. | bisulfite sequencing, sequence analysis software, short read, sequence mapping, bio.tools |
uses: Bowtie is listed by: OMICtools is listed by: bio.tools is listed by: Debian is related to: Bs-Seeker2 has parent organization: University of California at Los Angeles; California; USA |
PMID:20416082 | Free, Available for download, Freely available | OMICS_00578, biotools:bs_seeker | https://bio.tools/bs_seeker | SCR_005641 | Bisulfite Sequence Seeker | 2026-09-12 12:56:29 | 3 |
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