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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
NIS-Elements
 
Resource Report
Resource Website
1000+ mentions
Rating or validation data
NIS-Elements (RRID:SCR_014329) software toolkit, software application, data processing software, data analysis software, software resource Microscope imaging software suite used with Nikon products. NIS-Elements includes software applications for advanced and standard research, documentation, confocal microscopy, and high-content analysis., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. element, microscope imaging software, software suite, nikon is listed by: SoftCite
works with: Nikon: ECLIPSE Ti2 inverted microscope
THIS RESOURCE IS NO LONGER IN SERVICE SCR_014329 Nikon Instruments Software Elements, NIS Elements, Nikon Instruments Software 2026-08-03 09:35:41 3462
IMAGIC
 
Resource Report
Resource Website
100+ mentions
IMAGIC (RRID:SCR_014447) image processing software, software application, data processing software, image analysis software, software resource An image analysis software that can process spectra and other multi-dimensional data-sets. The software package is aimed at processing large data sets from (cryo-) electron microscopy, especially in the field of single particle analyses. This software can be used with light and raster-tunneling microscopes, computer tomographs, FT-IR spectrometers and other signal collecting devices. This resource provides three-dimensional data processing and angular reconstitution modules that allow the three-dimensional reconstruction with point-group symmetry from the two dimensional electron microscopy projections. These models aid in the analysis of the macromolecules. image analysis, spectra, multi-dimensional data, macromolecule, 3d processing, tomograph, spectrometer, software environment is listed by: SoftCite PMID:8742718 Commercial, Account needed for download SCR_014447 2026-08-03 09:35:40 217
Coot
 
Resource Report
Resource Website
10000+ mentions
Coot (RRID:SCR_014222) COOT model, software toolkit, software application, simulation software, data or information resource, software resource Software for macromolecular model building, model completion and validation, and protein modelling using X-ray data. Coot displays maps and models and allows model manipulations such as idealization, rigid-body fitting, ligand search, Ramachandran plots, non-crystallographic symmetry and more. Source code is available. software toolkit, simulation software, model manipulation, protein modeling, bio.tools is used by: PDB-REDO
is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
is related to: MolProbity
has parent organization: MRC Laboratory of Molecular Biology
PMID:15572765 Available for download, Acknowledgement requested biotools:coot http://strucbio.biologie.uni-konstanz.de/ccp4wiki/index.php/Coot, https://bio.tools/coot SCR_014222 Crystallographic Object-Oriented Toolkit 2026-08-03 09:35:33 14789
MolProbity
 
Resource Report
Resource Website
5000+ mentions
MolProbity (RRID:SCR_014226) software resource, web application A structure-validation web application which provides an expert-system consultation about the accuracy of a macromolecular structure model, diagnosing local problems and enabling their correction. MolProbity works best as an active validation tool (used as soon as a model is available and during each rebuild/refine loop) and when used for protein and RNA crystal structures, but it may also work well for DNA, ligands and NMR ensembles. It produces coordinates, graphics, and numerical evaluations that integrate with either manual or automated use in systems such as PHENIX, KiNG, or Coot. web application, consultation, macromolecular structure, structure validation, macromolecular crystallography is listed by: SoftCite
is related to: Phenix
is related to: Coot
has parent organization: Duke University; North Carolina; USA
Howard Hughes Medical Institute Predoctoral Fellowship ;
NIGMS GM-15000;
NIGMS GM-61302
DOI:10.1107/S0907444909042073 Acknowledgement requested, Requires Java and Javascript https://www.phenix-online.org/documentation/reference/molprobity_tool.html SCR_014226 2026-08-03 09:35:38 6313
LSM Image Examiner
 
Resource Report
Resource Website
1000+ mentions
Rating or validation data
LSM Image Examiner (RRID:SCR_014344) data management software, software resource, software application Software used to compile images obtained from the Zeiss LSM 510 confocal microscope. The browser can be used for general image archiving and handling and interactive measurement in labs and workgroups. Features include orthogonal sectioning, 3D cut function, 3D view with calculation of single projections, and interactive measurement functions in the overlay dialog, such as scale bar, distance, and area. data management software, image archive, image management, interactive measurement is listed by: SoftCite Available for download http://www.zeiss.com/microscopy/en_us/website/downloads/lsm-image-browser.html http://lsm-image-examiner.software.informer.com SCR_014344 LSM Image Browser 2026-08-03 09:35:41 1508
MassLynx
 
Resource Report
Resource Website
5000+ mentions
MassLynx (RRID:SCR_014271) data management software, data acquisition software, software application, data processing software, data analysis software, software resource Software which can acquire, analyze, manage, and share mass spectrometry data. MassLynx controls any Waters mass spectrometry system, from sample and solvent management components to mass spectrometer and auxiliary detectors. The software can acquire nominal mass, exact mass, MS/MS and exact mass MS/MS data. The software system also maintains and consolidates all user sample data. Optional Application Manager programs provide additional information for specific MS analyses and data., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. data acquisition software, data analysis software, data management software, mass spectrometry is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE SCR_014271 MassLynx MS Software 2026-08-03 09:35:39 5802
I-TASSER
 
Resource Report
Resource Website
1000+ mentions
I-TASSER (RRID:SCR_014627) software resource, data processing software, software application, data analysis software Web server as integrated platform for automated protein structure and function prediction. Used for protein 3D structure prediction. Resource for automated protein structure prediction and structure-based function annotation. Automated prediction, protein structure prediction, protein function prediction, protein 3D structure, amino acid sequence, alignment, simulation, 3D atomic model, protein, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
has parent organization: University of Michigan; Ann Arbor; USA
has parent organization: University of Kansas; Kansas; USA
NIGMS GM083107;
NIGMS GM084222
DOI:10.1186/1471-2105-9-40
DOI:10.1093/nar/gkv342
PMID:20360767
PMID:18215316
Free, Available for download, Freely available biotools:i-tasser, SCR_018803 https://bio.tools/i-tasser SCR_014627 Iterative Threading Assembly Refinement, Iterative Threading ASSEmbly Refinement 2026-08-03 09:35:33 3702
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) sequence analysis software, software application, data processing software, data analysis software, software resource Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks, https://bio.tools/cufflinks, https://sources.debian.org/src/cufflinks/ SCR_014597 2026-08-03 09:35:48 8838
Minitab
 
Resource Report
Resource Website
5000+ mentions
Minitab (RRID:SCR_014483) software resource, data processing software, software application, data analysis software A statistical software package that allows the user to import data, create graphs, and perform statistical analysis. It can perform basic statistical tests like descriptive statistics, hypothesis tests, confidence intervals, and normality tests as well as regression and ANOVA and quality assessment. data analysis, statistical analysis, hypothesis, confidence, descriptive is listed by: SoftCite SCR_014483 2026-08-03 09:35:30 5778
CVODE
 
Resource Report
Resource Website
50+ mentions
CVODE (RRID:SCR_014696) software resource, data processing software, software application, data analysis software Solver for stiff and nonstiff ordinary differential equation (ODE) systems (initial value problem), given in explicit form y' = f(t,y), based on Adams and BDF methods. It is one of the programs that makes up the Suite of Nonlinear and Differential/Algebraic Equation Solvers (SUNDIALS)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. data analysis software, solver, equation solver, ordinary differential equation, differential equation, stiff, nonstiff is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE SCR_014696 SUNDIALS CVODE 2026-08-03 09:35:49 56
KaleidaGraph
 
Resource Report
Resource Website
1000+ mentions
KaleidaGraph (RRID:SCR_014980) software application, data processing software, data analysis software, software resource, data visualization software Data analysis, graphing, and management application that allows users to import, manipulate, analyze data, and create customized plots. Plots include x-y probability, histogram, box, percentile, horizontal bar, stack bar, column, stack column, polar, and pie. Binned data can be exported to a histogram, step plot, or spike plot. KaleidaGraph works with Windows and Macintosh systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. custom graph, custom plot, publishable graph, publishable plot, data manipulation, curve fitting is listed by: SoftCite THIS RESOURCE IS NO LONGER IN SERVICE SCR_014980 2026-08-03 09:35:58 2788
MedCalc
 
Resource Report
Resource Website
10000+ mentions
MedCalc (RRID:SCR_015044) software resource, data processing software, software application, data analysis software Statistical software for ROC curve analysis. MedCalc performs several statistical tests such as method comparison, method evaluation, reference intervals, and meta-analysis. statistic, statistical analysis, roc curve, reference software is listed by: SoftCite Commercially available, Available for purchase, Trial available SCR_015044 2026-08-03 09:35:43 18070
BoxPlotR
 
Resource Report
Resource Website
100+ mentions
BoxPlotR (RRID:SCR_015629) software application, data processing software, web application, software resource, data visualization software Web tool written in R for generation of box plots with R packages shiny, beanplot4, vioplot, beeswarm and RColorBrewer, and hosted on shiny server to allow for interactive data analysis. Data are held temporarily and discarded as soon as session terminates.Represents both summary statistics and distribution of primary data. Enables visualization of minimum, lower quartile, median, upper quartile and maximum of any data set.Data matrix can be uploaded as file or pasted into application. May be downloaded to run locally or as virtual machine for VMware and VirtualBox. Box plot generation, customized box plot, data, plot, analysis is listed by: SoftCite
is related to: PlotsOfData
is related to: vioplot
Wellcome Trust ;
WTCCB ;
ERC ;
Genome Québec International Recruitment Award
PMID:24481215 Free, Available for download, Freely available SCR_018327 https://github.com/VizWizard/BoxPlotR.shiny SCR_015629 2026-08-03 09:36:03 360
oligo
 
Resource Report
Resource Website
1000+ mentions
oligo (RRID:SCR_015729) software application, data processing software, source code, data analysis software, software resource Software package to analyze oligonucleotide arrays (expression/SNP/tiling/exon) at probe-level. It currently supports Affymetrix (CEL files) and NimbleGen arrays (XYS files). oligonucleotide, microarray gene expression, r, oligonucleotide array, snp, gene expression, probe-level, affymetrix array, cel file, and nimblegen array, xys file, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
CAPES (Coordenação de Aprimoramento Pessoal de Nível Superior) ;
NCRR R01RR021967;
NHGRI P41HG004059
PMID:20688976 Free, Available for download, Runs on Mac OS, Runs on Windows biotools:oligo https://bio.tools/oligo SCR_015729 oligo package 2026-08-03 09:36:24 1749
GeneMarker
 
Resource Report
Resource Website
1000+ mentions
GeneMarker (RRID:SCR_015661) software resource, data processing software, software application, data analysis software Genotype analysis software which enhances the speed, accuracy, and ease of analysis. The software is an alternative to Applied BioSystems Genotyper®, GeneScan®, and other genotype analysis software. genotype, gene analysis is listed by: SoftCite Commercially available, Trial available, Runs on Mac OS, Runs on Windows, Runs on Linux SCR_015661 GeneMarker: The Biologist Friendly Software 2026-08-03 09:36:22 1541
Phobius
 
Resource Report
Resource Website
100+ mentions
Phobius (RRID:SCR_015643) production service resource, web service, analysis service resource, data access protocol, service resource, software resource Web application for combined transmembrane topology and signal peptide prediction. Used for whole genome annotation of signal peptides and transmembrane regions. Predictor is based on hidden Markov model (HMM) that models different sequence regions of signal peptide and different regions of transmembrane protein in series of interconnected states. Signal peptide prediction, whole genome annotation, transmembrane region, protein prediction, transmembrane topology, signal peptide, fasta, hidden markov model is listed by: SoftCite PMID:15111065
PMID:30976793
Freely Available, Free, Available for download SCR_018767 http://phobius.binf.ku.dk/, https://www.ebi.ac.uk/Tools/pfa/phobius/ SCR_015643 PHOBIUS 2026-08-03 09:36:03 498
Fiji
 
Resource Report
Resource Website
10000+ mentions
Fiji (RRID:SCR_002285) Fiji image processing software, software application, data processing software, source code, software resource Software package as distribution of ImageJ and ImageJ2 together with Java, Java3D and plugins organized into coherent menu structure. Used to assist research in life sciences. imaging, microscopy, windows, linux, java, mac osx, bio.tools uses: Fiji/ImageJ
is used by: MuscleJ
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: ImageJ
is related to: SynapseLocator
is related to: Golddigger
is related to: Analyze Spheroid Cell Invasion In 3D Matrix
has parent organization: Max Planck Institute of Molecular Cell Biology and Genetics; Dresden; Germany
has plug in: BioVoxxel Toolbox
has plug in: imctools
has plug in: Big Data Processor
has plug in: Sholl Analysis
has plug in: SAIBR
has plug in: TWOMBLI
PMID:22743772 Free, Available for download, Freely available, Acknowledgement requested SciRes_000137, biotools:Fiji https://github.com/fiji/fiji, https://bio.tools/Fiji SCR_002285 Fiji is just ImageJ 2026-08-03 09:31:45 37202
JCB DataViewer
 
Resource Report
Resource Website
10+ mentions
JCB DataViewer (RRID:SCR_002633) JCB DataViewer data repository, data or information resource, database, image repository, storage service resource, service resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on January 14,2026. A web-based, multi-dimensional image data-viewing application for original microscopy image datasets associated with articles published in The Journal of Cell Biology, a peer-reviewed journal published by The Rockefeller University Press. The JCB DataViewer can host multidimensional fluorescence microscopy images, 3D tomogram data, very large (gigapixel) images, and high content imaging screens. Images are presented in an interactive viewer, and the scores from high content screens are presented in interactive graphs with data points linked to the relevant images. The JCB DataViewer uses the Bio-Formats library to read over 120 different imaging file formats and convert them to the OME-TIFF image data standard. Image data are archived by the Journal and may be freely accessed by readers using the JCB DataViewer. Download of author-provided image data and associated metadata in OME-TIFF format is also possible with author permission, allowing for independent analysis of image data irrespective of acquisition or viewing software. Although the JCB DataViewer is designed to host and facilitate sharing and analysis of original microscopy image data, authors may also upload other types of original image data as supplements to their manuscripts, including histology and electron micrographs and digital scans of gels or blots. microscopy, standardization, data sharing, archiving, data management, metadata standard, visualization, analysis, image collection, histology, electron micrograph, digital scan, gel, blot is listed by: FORCE11
is listed by: SoftCite
is related to: OME-TIFF Format
has parent organization: Rockefeller University; New York; USA
Glencoe Software ;
OME - Open Microscopy Environment
PMID:22869591 THIS RESOURCE IS NO LONGER IN SERVICE nlx_156057, r3d100010895 https://doi.org/10.17616/R3PW4G SCR_002633 2026-08-03 09:32:03 14
CLC Main Workbench
 
Resource Report
Resource Website
10+ mentions
CLC Main Workbench (RRID:SCR_000354) CLC Main Workbench software toolkit, software resource A suite of software for DNA, RNA and protein sequence data analysis. The software allows for the analysis and visualization of Sanger sequencing data as well as gene expression analysis, molecular cloning, primer design, phylogenetic analyses, and sequence data management. sequencing, analysis, cloning, data, management, molecular, gene, genome, dna, rna is listed by: OMICtools
is listed by: SoftCite
Restricted OMICS_01813 SCR_000354 2026-08-02 09:02:51 31
Eigensoft
 
Resource Report
Resource Website
1000+ mentions
Issue
Eigensoft (RRID:SCR_004965) EIGENSOFT software toolkit, software resource EIGENSOFT package combines functionality from our population genetics methods (Patterson et al. 2006) and our EIGENSTRAT stratification method (Price et al. 2006). The EIGENSTRAT method uses principal components analysis to explicitly model ancestry differences between cases and controls along continuous axes of variation; the resulting correction is specific to a candidate marker''s variation in frequency across ancestral populations, minimizing spurious associations while maximizing power to detect true associations. The EIGENSOFT package has a built-in plotting script and supports multiple file formats and quantitative phenotypes. Source code, documentation and executables for using EIGENSOFT 3.0 on a Linux platform can be downloaded. New features of EIGENSOFT 3.0 include supporting either 32-bit or 64-bit Linux machines, a utility to merge different data sets, a utility to identify related samples (accounting for population structure), and supporting multiple file formats for EIGENSTRAT stratification correction. population genetics, genetics, stratification, variation is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
has parent organization: Harvard Medical School; Massachusetts; USA
PMID:17194218
DOI:10.1038/ng1847
OMICS_07868, nlx_93059 https://sources.debian.org/src/eigensoft/ http://genepath.med.harvard.edu/~reich/Software.htm SCR_004965 EIGENSOFT Software 2026-08-02 09:04:06 1225

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