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https://education.musc.edu/colleges/medicine/departments/pharmacology/redox-center/cores/analytical-redox-biology-core

Core provides analytical redox biochemistry methods and mentoring support for COBRE junior faculty with goal to advance their research endeavors, publications and fundability. Specific aims are:Provide ROS /RNS identification and quantification, Perform quantitative analysis of ROS/RNS. Provides expertise and technology for in depth biochemical analysis of thiol-centered enzyme activities and define protein:protein interactions.

Proper citation: South Carolina Medical University Analytical Redox Biology Core Facility (RRID:SCR_017955) Copy   

•   Source: SciCrunch Registry

https://education.musc.edu/colleges/medicine/departments/pharmacology/redox-center/cores/cell-and-molecular-imaging-core

Core provides COBRE investigators access and assistance for high end laser scanning confocal/multiphoton/super-resolution microscopy and related imaging techniques. Houses confocal/multiphoton systems: Zeiss LSM 880 NLO Quasar confocal/multiphoton microscope with Fast Airyscan super-resolution detector; Olympus FV1200 silicone oil optics multiphoton microscope configured especially for intravital imaging; Olympus FV10i LIV confocal microscope with water immersion optics for live cell imaging; Zeiss LSM 510 META laser scanning confocal microscope for general purpose imaging of live and fixed specimens; BD CARV II disk-scanning confocal microscope for video rate real-time confocal imaging providing sophisticated imaging technologies, expertise and training.

Proper citation: South Carolina Medical University Cell and Molecular Imaging Core Facility (RRID:SCR_017954) Copy   

•   Source: SciCrunch Registry

https://www.feinberg.northwestern.edu/research/cores/units/structural-bio.html

Core provides equipment, training, technical support, and maintenance of equipment for studying structures of biological macromolecules and materials. Serves with expertise in structural and computational biology. Services offered include Macromolecular Structure Determination and Analysis,Macromolecular crystallography at LS-CAT,Robotics equipment for crystallization experiments,UV crystal imaging capabilities,Software for structure analysis,Graphics facilities for visualization/presentation of molecular structures,Computer servers specialized for structural biology calculationss,Support and Training ,X-ray crystallography, from designing crystallization experiments to structure determination and refinemen,Molecular graphics for analysis and presentation,CryoEM and EM training.Resources Available:Crystallography Art Robbins, Inc. Phoenix and Gryphon crystallization robots,TTP Labtech Dragonfly liquid handler for crystal tray setup,Jansi UVEX UV/Vis microscope/imaging system,Stereomicroscopes (camera equipped, at room temperature and 4 degrees C),Incubators for temperature-controlled crystallization,Coordination of access to LS-CAT for Northwestern University users,CryoEM,JEOL 3200FS TEM equipped with in-column energy filter (omega filter), field emission gun capable of operating at 200 or 300 kV and Gatan K2 Summit Direct Electron Detector,JEOL 1400 with Gatan 4k x 4k Ultrascan CCD camera,Solarus Plasma Cleaner and Pelco easyGlow Discharge Cleaning System,Cressington 308R carbon coater,Gatan Cryoplunge 3 and FEI Vitrobot Mark IV,Gatan 626 cryoholders with 655 Turbo pump stations.Resources available Computational:50+ node cluster running Linux including several single- and multi-GPU nodes,7 Quad-core Intel Xeon 3.4GHz workstations (3D stereo equipped for visualization and model building) 3 Dual Quad-core Intel Xeon 3.5GHz workstations with GPU computing capabilities (3D stereo equipped for visualization, model building, and GPU computing),LTO6 writers for quick data backup,45 tape LTO6 system for continuous data backup,Over 200 Tb of disk storage including RAID systems,10 Gigabit fiber Ethernet connection to APS.Software Crystallography,CCP4 suite,PHENIX,SHARP,SOLVE,HKL2000,XDS,CryoEM,CryoSparc,Relion3,Leginon,cisTEM,Appion,NMR,CNS,FELIX,Aria Modeling, graphics, and simulations,COOT,Pymol,Chimera,APBS,GROMACS,AMBER,VMD/NAMD.

Proper citation: Northwestern University School of Medicine Structural Biology Core Facility (RRID:SCR_017952) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/geologicalsciences/resources/research-facilities/raman-microspectroscopy-lab

Core research facility housed in Department of Geological Sciences for fast, non-destructive characterization and chemical imaging of diverse materials spanning minerals (thin sections and powders), biological samples, fluids, dissolved gases, and much more.

Proper citation: University of Colorado Boulder Raman Microspectroscopy Lab Core Facility (RRID:SCR_019305) Copy   

•   Source: SciCrunch Registry

https://med.virginia.edu/advanced-microscopy-facility/

Advanced Microscopy Facility is microscopy service and shared instrumentation facility in University of Virginia biomedical research community. Pprovides expertise and instrument access for electron and light microscopy imaging technologies as well as image analysis tools and services for basic scientists and clinical researchers within University of Virginia and across Commonwealth.

Proper citation: Virginia University School of Medicine Advanced Microscopy Core Facility (RRID:SCR_018736) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/earthscience/resources/research-facilities/organic-and-isotope-geochemistry-laboratory

Shared analytical facility for multidisciplinary and collaborative research in fields as diverse as biogeochemistry, geobiology, astrobiology, environmental microbiology, paleoceanography, paleoclimatology, and energy, among others.Focuses on extraction, purification, separation, and chemical and isotopic characterization of organic molecules extracted from environmental and culture samples.

Proper citation: University of Colorado Boulder Organic Geochemistry Laboratory Core Facility (RRID:SCR_019301) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/lab/biocore/

Purpose is to connect MCDB, EBIO, and IPHY researchers to campus research resources.

Proper citation: University of Colorado Boulder BioCore Core Facility (RRID:SCR_019302) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/geologicalsciences/resources/research-facilities/u-thhe-thermochronology-lab

Fully equipped (U-Th)/He thermochronology facility.

Proper citation: University of Colorado Boulder CU Thermochronology Research and Instrumentation Lab Core Facility (RRID:SCR_019303) Copy   

•   Source: SciCrunch Registry

http://www.biotech.ufl.edu/cores/gene-expression-genotyping/

Core provides services and consultation on Single Cell RNA-Seq, RNA-Seq, 16s metagenomics and Affymetrix gene expression arrays. High-throughput RNA-seq libraries, 16s libraries and sequencing capture libraries can be done by using Agilent Bravo robot. QuantiGene RNA Assays measure up to 80 gene targets directly with degraded and cross-linked RNA in FFPE tissues and blood, with no RNA purification required.BioRad QX200 AutoDG Droplet Digital PCR System provides absolute quantification of target DNA or RNA molecules with greater precision and sensitivity than qPCR, sensitivity off ddPCR System can facilitate expanded analysis of single cells. Genotyping services include fragment analysis using AB3730, 96 capillary technology, development of microsatellite libraries using Illumina sequence data, and genotyping using mouse tails or ear punches.

Proper citation: University of Florida ICBR Gene Expression and Genotyping Core Facility (RRID:SCR_019145) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/geologicalsciences/resources/research-facilities/earth-systems-stable-isotope-laboratory

Designed to measure relative abundance of stable isotopes of light elements and molecules.

Proper citation: University of Colorado Boulder Earth Systems Stable Isotope Lab Core Facility (RRID:SCR_019300) Copy   

•   Source: SciCrunch Registry

https://www.cardiff.ac.uk/central-biotechnology-services

Core provides facilities including cell analysis and imaging, genomics and bioinformatics, proteins and diagnostics. Services include experimental design advice, sample preparation,data generation,data analysis.

Proper citation: Cardiff University Central Biotechnology Services Core Facility (RRID:SCR_019141) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/lab/biochem-instruments/

Provides access to multitude of instruments and techniques, including EPR, CD and fluorescence spectroscopy, DLS, Sec-MALS, ITC, MST, stopped-flow spectroscopy, chemical quench-flow, imaging systems, centrifuges, scintillation counters, sonicators and more.

Proper citation: Colorado University at Boulder Biochemistry Shared Instruments Pool Core Facility (RRID:SCR_018986) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/facility/biochemistry-cell-culture/

Provides investigators within the Department a user-friendly, shared environment where researchers can advance discovery in diverse areas such as cancer biology, drug discovery, nanomaterial analysis and basic life science. Provides Biosafety Cabinets, CO2 Incubators including viral and variable oxygen (tri-gas) Insect cell incubator and shaker, Large-scale mammalian incubator, Routine mycoplasma testing,FBS testing,Training, In-house media preparation.

Proper citation: Colorado University at Boulder Biochemistry Cell Culture Core Facility (RRID:SCR_018988) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/ecenter/greenlabs

Core provides help to efficiently use of resources by involving individual laboratory members in identifying opportunities for efficiency in their laboratory and promoting efficient behaviors, upgrading inefficient laboratory equipment and techniques, compelling labs to use lab space, fume hoods, and lab equipment resources efficiently and in collaborative manner, developing means to reduce large flow of lab materials into waste stream, promoting green chemistry and chemical re-use where feasible.Core provides instruments including Shared Stirling Ultracold Ultra Low Temperature Freezer and Shared Thermo Scientific Ultracold Ultra Low Temperature Freezer.

Proper citation: Colorado University at Boulder Green Labs Core Facility (RRID:SCR_018989) Copy   

•   Source: SciCrunch Registry

https://www.colorado.edu/facility/cosinc/

Multidisciplinary core research facility and service center, within College of Engineering and Applied Science, that provides access to equipment in areas of micro and nanofabrication, nanomaterials characterization and metrology and offers expertise and advanced hands-on training. Offers common platform for convergence of multiple scientific and engineering disciplines and facilitates collaborative research with strategic partners and information exchange.

Proper citation: Colorado University at Boulder Shared Instrumentation in Nanofabrication and Characterization Core Facility (RRID:SCR_018985) Copy   

•   Source: SciCrunch Registry

http://www.biotech.ufl.edu/cores/proteomics/

Provides service and training in proteomics and mass spectrometry. Services in proteomics, differential proteomics, two dimensional difference gel electrophoresis, isobaric tags for relative and absolute quantitation, tandem mass tags, iodoTMT, stable isotope labeling with amino acids in cell culture, quantification of proteins by label-free LC-MS/MS, and analysis of protein post translational modifications and molecular weight determination. Core offers education, consultation, data processing and reporting, and support of grant application.

Proper citation: University of Florida ICBR Proteomics and Mass Spectrometry Core Facility (RRID:SCR_019151) Copy   

•   Source: SciCrunch Registry

https://biotech.ufl.edu/next-gen-dna/

Core provides platforms including Illumina NextSeq500 and MiSeq, HiSeq3000 and Pacific Biosciences SEQUEL system. Offers free consultation in sequencing technologies including read length, error rate, predominant type of error, data output/run, speed, cost. Services include de novo sequencing of whole genomes, targeted sequencing, transcriptome sequencing, chromatin immunoprecipitation sequencing, methylation analysis and metagenomics.

Proper citation: University of Florida ICBR NextGen DNA Sequencing Core Facility (RRID:SCR_019152) Copy   

•   Source: SciCrunch Registry

https://research.chusj.org/en/Services/Plateformes/Plateforme-d-imagerie-microscopique

Core offers light microscopy instruments, image analysis tools, consultations and training. Platform for imaging by microscopy.

Proper citation: Sainte-Justine University Hospital Research Center Platform for Imaging by Microscopy Core Facility (RRID:SCR_019032) Copy   

•   Source: SciCrunch Registry

http://www.jiamdiffraction.com

Provides users with access to Panalytical XPert3 MRD and Panalytical Empyrean XRD platforms to perform variety of X-ray diffraction experiments including phase identification, phase quantification, crystallite size and microstrain determination, pole figures, residual stress, high-temperature in situ measurements. These instruments are available for both assisted and unassisted use with prior approval.

Proper citation: University of Tennessee JIAM Diffraction Core Facility (RRID:SCR_018677) Copy   

•   Source: SciCrunch Registry

https://www.waksman.rutgers.edu/fermentation

Provides fermentation services. Produces range of bulk biologics including antimicrobials, cosmetic substrates, flavors/fragrances, biopesticides/bioherbicides and plasmid derived proteins, enzymes, growth factors and diagnostics. Exceptions for pathogenic or opportunistic organisms and mammalian and insect cell lines. Includes Material Preparation Laboratory,Fermentation In-Process/Computer Control,Product Recovery and Analytical Services.

Proper citation: Rutgers Waksman Institute of Microbiology Cell and Cell Products Fermentation Core Facility (RRID:SCR_018676) Copy   

•   Source: SciCrunch Registry