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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.norch.org/metabolic-phenotyping-core/
Core that provides NORCH investigators with access to model creation and detailed metabolic phenotyping. Its services include: model generation, including genomic targeting and production of metabolically relevant cell types; metabolic characterization of patient-derived, user-provided, or model generated samples; consultation on model development and metabolic characterization projects; and training for Core techniques in model generation and detailed metabolic characterization.
Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Phenotyping Core (RRID:SCR_015429) Copy
http://www.norch.org/metabolic-imaging-core/
Core that links a variety of imaging facilities providing services to NORCH investigators who currently require or plan to conduct human studies using imaging research instrumentation and expertise. Its goal is to provide users with access to imaging technology for in-vivo phenotyping of human tissues for nutrition, obesity and metabolism studies.
Proper citation: Nutrition and Obesity Research Centers at Harvard Metabolic Imaging Core (RRID:SCR_015426) Copy
https://www.uab.edu/medicine/cysticfibrosis/about/translational-core
Core that provides human primary nasal airway epithelial cells and bronchial airway epithelial cells, expertise in the nasal potential difference measurement, and a means to understand pathogenesis of cystic fibrosis and other metabolic diseases.
Proper citation: Gregory Fleming James Cystic Fibrosis Research Center Cystic Fibrosis Clinical and Translational Core (RRID:SCR_015399) Copy
https://nyonrc.cumc.columbia.edu/content/molecular-biologymolecular-genetics-core
Core whose goal is to assist investigators in applying the tools and technologies of molecular genetics and genomics to elucidate the molecular-genetic bases of obesity and its comorbidities. Its services include consultation on study design, analysis, and applicable molecular biological techniques and developing and making research tools and reagents.
Proper citation: New York Obesity Nutrition Research Center Molecular Biology and Molecular Genetics Core (RRID:SCR_015436) Copy
http://depts.washington.edu/uwnorc/core-facilities/adipose-tissue-and-obesity-core/
Core that provides affiliated investigators with assistance for in vivo and in vitro studies in both subcutaneous and visceral human adipose tissue. Body and liver fat measurement by DXA and MRI are also provided, as is support for translational studies that assist investigators in the design conduct of clinical obesity research.
Proper citation: University of Washington Nutrition and Obesity Research Center Adipose Tissue and Obesity Core (RRID:SCR_015481) Copy
http://depts.washington.edu/cfrtc/genomics/
Core provides genomics-based tools, data management and analysis tools, and creates platforms that integrate data from the Clinical and Immunology Cores for human samples and bacterial isolates. Services include consultation and experimental design assistance for using new-generation sequencing technology, data analysis, bioinformatic support, data access and storage, high throughput and new-generation whole-genome sequencing, and RNA-seq analysis of transcriptomes.
Proper citation: University of Washington Genomics Core Cystic Fibrosis Research Translation Center and Research Development Program (RRID:SCR_015404) Copy
http://www.med.upenn.edu/gtp/immunology.shtml
Core facility which provides a variety of assay services to evaluate cell-mediated and humoral responses to in animal models of gene therapies.
Proper citation: University of Pennsylvania Center for Molecular Therapy for Cystic Fibrosis Immunology Core (RRID:SCR_015409) Copy
https://medicine.uiowa.edu/genetherapy/research-cores/cells-and-tissue-core
Core that provides centralized access to non-cystic fibrosis and cystic fibrosis tissue specimens and airway cells used for model systems to assess gene transfer to the airway and pathophysiology in cystic fibrosis.
Proper citation: University of Iowa Center for Gene Therapy Cell Tissue Core (RRID:SCR_015410) Copy
http://www.med.unc.edu/cgibd/cores/biostatistics
Core facility that provides comprehensive statistical and data management services. Its statistical analysis services include study design, power and sample size analysis, randomization, statistical programming, consultation and the development of analysis plans, graphs, figures and reports.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Biostatistics and Data Management Core (RRID:SCR_015616) Copy
http://www.med.unc.edu/cgibd/cores/histology
Core facility that provides a full range of histology services, encompassing routine and specialized grossing, tissue processing, paraffin embedding, microtomy, H&E and special staining, and immunohistochemistry. It also offers image analysis and consultations to CGIBD members and non-members.
Proper citation: University of North Carolina Center for Gastrointestinal Biology and Disease Histology Core (RRID:SCR_015614) Copy
http://www.med.upenn.edu/molecular/core_morphology.shtml
Core facility that provides histological services, equipment usage, and technical expertise to digestive and liver research projects.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Molecular Pathology and Imaging Core (RRID:SCR_015618) Copy
http://www.med.upenn.edu/molecular/core_molecular.shtml
Core facility that provides services that will enhance the analysis of both host and microbial biological processes as well as facilitate translation into the clinical arena via human subject research.
Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Host-Microbial Analytic and Repository Core (RRID:SCR_015620) Copy
http://livercenter.ucsf.edu/pathology-imaging-core
Core that provides services from routine liver histology to complex microscopy and image analysis.
Proper citation: UCSF Liver Center Pathology & Imaging Core (RRID:SCR_015599) Copy
A project''s launch partners are three research studies that have an established record crowd-sourcing health data for research studies. One initiatives is the Personal Genome Project, established at geneticist George Church''s Harvard lab, which creates a freely available scientific resource that brings together genomic, environmental and human trait data. These data are donated by volunteers enrolled in a PGP study from our global network. A second partner is the GoViral project, started by researchers at Harvard University and New York University, which enables volunteers to provide easy-to-collect specimens when sick with a respiratory infection, and get confirmation of what type of viral illness they have. By testing samples when symptoms occur, participants can validate symptomatic reports as well as enable a better understanding of the representativeness of self-reported data and symptom profiles for different acute respiratory illnesses. Third on the list is the American Gut project, based at the University of California-San Diego and the University of Chicago, which is studying the vast microbial flora that inhabit the human digestive system from crowd-sourced (and properly sealed) samples of feces or skin swabs.
Proper citation: Open Humans Project (RRID:SCR_013669) Copy
A global health company contributing to the systemic improvement of health care delivery and the health of communities. We are transforming health care by eliminating error, variance and waste for health care providers and consumers around the world. Our solutions optimize processes for health care organizations ranging from single-doctor practices to entire countries, for the pharmaceutical and medical device industries, and for the field of health care as a whole. Our solutions are licensed by more than 9,000 facilities worldwide. We invite you to join us in our quest to make health care become all it should be. Since our company began, we have been committed to transformational change in the vital task of keeping people well. Now more than ever, our focus is on developing the innovations that will help improve the entire health care system. Ultimately, as our CEO Neal Patterson has said, health care is personal. Because in the end, nothing matters more than our health and our families. We''re changing the way people: * Use and share information ** We empower providers to base decisions on best clinical evidence. ** We coordinate care across traditionally fragmented health care systems. ** We provide clinical organizations with the reliability, flexibility and continuous innovation available through cloud-based intelligence. ** We provide contextually relevant information to the right people at the right time. * Pay for health and care ** We believe IT investment must be matched with innovative payment models that are much easier to navigate. ** We are replacing the current, claims-based system with streamlined electronic payments. ** We develop ways to reward people and their providers for proactively achieving positive health goals. * Think about health ** We empower people to actively engage in their health by providing them with a standards-based, lifetime Personal Health Record. ** We are replacing the reactive sick care model with a proactive, personalized plan for health.
Proper citation: Cerner Millenium (RRID:SCR_013581) Copy
http://www.dbmi.pitt.edu/nlpfront
THIS RESOURCE IS NO LONGER IN SERVICE, documented on July 17, 2013. Repository of de-identified clinical reports available for NLP researchers has been designed. Work with the AMIA NLP working group in designing annotation schemas and obtaining annotations, design a repository for shareable annotations, help design and execute a shared task in IE from clinical reports. The University of Pittsburgh NLP Repository contains clinical reports that are available to the community for NLP research purposes and comprises: # Report Repository - one month of de-identified clinical reports from multiple hospitals and # Annotation Repository - annotations performed on reports from the Report Repository. Anyone performing annotations on reports from the NLP Repository is required to deposit their annotations. The Repository contains reports of the following types generated from multiple hospitals during a single month: * History and Physicals * Progress Notes * Consultation Reports * Radiology Reports * Surgical Pathology Reports * Emergency Department Reports * Discharge Summaries * Operative Reports * Cardiology Reports
Proper citation: Open Clinical Report Repository (RRID:SCR_013585) Copy
http://www.fda.gov/Drugs/GuidanceComplianceRegulatoryInformation/Surveillance/AdverseDrugEffects/
Database that contains information on adverse event and medication error reports submitted to FDA. The database is designed to support the FDA's post-marketing safety surveillance program for drug and therapeutic biologic products.
Proper citation: FDA Adverse Event Reporting System Data (RRID:SCR_013718) Copy
http://www.uzh.ch/keyinst/loreta#_NOTES:
A software application which computes images of electric neuronal activity from EEG and MEG. Standard Low Resolution Brain Electromagnetic Tomography, or sLORETA, localizes “test point sources” exactly (under ideal conditions) when estimating electric neuronal generators. This property can be generalized to any source distribution, based on the principles of linearity and superposition. However, it would be noted that sLORETA has very low spatial resolution.
Proper citation: sLORETA (RRID:SCR_013829) Copy
A cancer research center whose goal is to offer innovative technoligies to spur the develpment of new methods of diagnosing and treating cancer. CNIO contains a variety of programs of investigation, including a biotechnology program, a clinical research program, and a molecular oncology program. CNIO also provides services that allow researchers to access and use technologies and tools such as cytogenetics and monoclonal antibodies, and hosts a biomedical biobank.
Proper citation: Spanish National Cancer Research Center (RRID:SCR_014054) Copy
https://www.genome.gov/27550959/undiagnosed-diseases-network-udn/
A network of clinical sites and core laboratories to accelerate discovery and innovate the way medical professionals diagnose and treat patients with previously undiagnosed diseases. It will serve to test whether this type of cross-disciplinary approach to disease diagnosis is feasible to implement in academic medical centers. It also provides clinical training of contemporary genomic approaches in diagnosing disease.
Proper citation: Undiagnosed Diseases Network (RRID:SCR_014415) Copy
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