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http://biophysics.com

Instrument that electronically monitors cells grown in tissue culture. It is a real-time, label-free, impedance-based method to study the activities of cells. Used for analysis in cell biological dynamics for cells that do not form tight monolayers such as cancer cell lines. The system supports communication to a PC, allowing data acquisition, analysis, and storage.

Proper citation: ECIS Model (RRID:SCR_016367) Copy   

•   Source: SciCrunch Registry

http://nufab.northwestern.edu

Central micro/nano fabrication facility of Northwestern University. Provides range of nanofabrication equipment and technical expertise. Supports research in all areas of science, engineering, medicine, and interdisciplinary fields.

Proper citation: Northwestern University Micro/Nano Fabrication Core Facility (RRID:SCR_017779) Copy   

•   Source: SciCrunch Registry

http://www.cme.ufpr.br/

Laboratory to support scientific research in system of multi user operation of UFPR. Available equipment in electron microscopy.

Proper citation: Federal University of Parana Center for Electron Microscopy core facility (RRID:SCR_017568) Copy   

•   Source: SciCrunch Registry

https://www.brown.edu/research/facilities/bioimaging/

Core provides equipment and training dedicated to high resolution imaging in life sciences. Facility includes Transmission Electron Microscope, a Scanning Electron Microscope, three Fluorescence Microscopes, Fluorescence Stereomicroscope, four Confocal Laser Scanning Microscopes,Multiphoton Microscope, and software for image analysis.Maintains equipment for sample preparation, including critical point dryer, sputter coater, and microtomes for ultrathin sectioning. Listed within CoresRI.org.

Proper citation: Brown University Leduc Bioimaging Core Facility (RRID:SCR_017861) Copy   

•   Source: SciCrunch Registry

http://xray.facilities.northwestern.edu/

Core provides general purpose x-ray equipment for diffraction and fluorescence studies. Examples of current measurements are: powder diffraction, single-crystal diffraction, thin-film reflectivity, thin-film diffraction, crystal truncation rod scattering, small angle scattering, Laue diffraction, residual stress, pole figures, EDX-ray fluorescence, x-ray standing waves, high-resolution x-ray diffraction, and grazing incidence small angle scattering.

Proper citation: Northwestern University Jerome B. Cohen X-ray Diffraction Core Facility (RRID:SCR_017866) Copy   

•   Source: SciCrunch Registry

http://www.scripps.edu/florida/technologies/xray/contacts.html

Core provides equipment and resources for crystallographic analysis of target macromolecules and small inorganic or organic molecules. Performes crystallization, X-ray diffraction data collection (both in-house and synchrotron sources) processing, phasing, crystallographic refinement, model building, and visualization. Structural data provide information including biological functions, 3D-folding, ligand binding (small molecule or protein), or mutational effect of target macromolecules. Services include Crystallization Screening; Data Collection Service: Diffraction experiments will be performed at in-house X-ray facility as well as synchrotron beam lines; Structure Determination and Analysis: complete data set collected at home or synchrotron will be processed for inorganic, organic, protein or nucleic acid structure determination, model building and crystallographic refinement. Other Structural Biology Related Services: core facility offers thorough analysis of macromolecular structure for publication or grant applications, also provides computational experiments such as homology modeling and in silico ligand docking.

Proper citation: Scripps Research Institute - Florida X ray Crystallography Core Facility (RRID:SCR_017835) Copy   

•   Source: SciCrunch Registry

http://iubemcenter.indiana.edu

Core provides access to electron microscopy equipment and services which includes AFS 2 Freeze Substitution robot,Denton DV502 Carbon Evaporator,JEOL JEM 1010,JEOL JEM 1400plus,JEOL JEM 3200FS,Polaron E5100 sputter coater,Vitrobot Mk3,Wohlwend High Pressure Freezer. Users have to be included on user e-mail lists and have iLab account in order to use core.

Proper citation: Indiana University - Bloomington Electron Microscopy Center Core Facility (RRID:SCR_017845) Copy   

•   Source: SciCrunch Registry

http://www.scripps.edu/florida/technologies/metaboliccore/index.html

Core provides researchers with equipment and expertise required for multi-dimensional imaging of cells and tissues at high resolution and to perform quantitative image analysis. Resources include widefield, confocal, multi-photon, TIRF, super-resolution and electron microscopy, as well as equipment for live cell imaging and image analysis. Services include sample preparation, imaging, molecular localization, and image analysis. Provides training, technical support, sample preparation, imaging assistance, collaboration and consultation.

Proper citation: Scripps Research Institute - Florida Core Microscopy Core Facility (RRID:SCR_017848) Copy   

•   Source: SciCrunch Registry

https://www.brown.edu/research/facilities/structural-biology/

Core provides equipment used for structural modeling in crystals and in solution, using X-ray diffraction and scattering, as well as magnetic resonance.

Proper citation: Brown University Structural Biology Core Facility (RRID:SCR_017900) Copy   

•   Source: SciCrunch Registry

https://www.labx.com/product/sciex-api-5000

Triple quadrupole liquid chromatography mass spectrometer for analysis of bioanalytical samples. It can be used for DMPK and ADME studies.API 5000 LC/MS/MS System delivers the lowest limits of detection for the most demanding DMPK and ADME studies.

Proper citation: SCIEX:: API 5000 Triple Quadrupole Liquid Chromatography Mass Spectrometer System (RRID:SCR_018437) Copy   

•   Source: SciCrunch Registry

http://tools.thermofisher.com/content/sfs/manuals/cms_041850.pdf

Automated peptide synthesizer for chain assembly steps in solid phase peptide synthesis or FastMoc chemistry. Data is based on conductance or ultraviolet UV absorbance of reagent, solutions, and solvents in the synthesis cycle.

Proper citation: Thermo Fisher: Applied Biosystems: 433A Peptide Sequencer (RRID:SCR_018440) Copy   

•   Source: SciCrunch Registry

https://devsci.northwestern.edu/neurodevelopmental-resource-core-services/

Core provides services in support of research, education, and assessment technology related to neurodevelopmental research methods. Services include Scientific Consultation, Workshops and Training,EEG/ERP,Eye-tracking,Clinical and Behavioral Measure Services.Services include Data Collection, Use of Equipment, Experimental Task Creation and Preparation.

Proper citation: Northwestern University DevSci Neurodevelopmental Core Facility (RRID:SCR_017957) Copy   

•   Source: SciCrunch Registry

http://matci.facilities.northwestern.edu

Core offers characterization and sample preparation equipment. Characterization techniques include optical microscopy, thermal imaging, thermal analysis (DSC, TGA), hardness testing (Vicker, Knoop, Rockwell), electronic characterization (Hall Effect, Impedance Spectroscopy, Kelvin Probe, Charge Transport) and rheological characterization. Sample and surface preparation capabilities include mounting (castable mounts, hot pressure mounting, vacuum impregnation), cutting, sectioning and wafer dicing, polishing/grinding, electropolishing, ion beam milling and cross-sectional polishing. Tube and box furnaces are available with temperature range up to 1700C for thermal processing.

Proper citation: Northwestern University Materials Characterization and Imaging Core Facility (RRID:SCR_017947) Copy   

•   Source: SciCrunch Registry

https://www.feinberg.northwestern.edu/research/cores/units/structural-bio.html

Core provides equipment, training, technical support, and maintenance of equipment for studying structures of biological macromolecules and materials. Serves with expertise in structural and computational biology. Services offered include Macromolecular Structure Determination and Analysis,Macromolecular crystallography at LS-CAT,Robotics equipment for crystallization experiments,UV crystal imaging capabilities,Software for structure analysis,Graphics facilities for visualization/presentation of molecular structures,Computer servers specialized for structural biology calculationss,Support and Training ,X-ray crystallography, from designing crystallization experiments to structure determination and refinemen,Molecular graphics for analysis and presentation,CryoEM and EM training.Resources Available:Crystallography Art Robbins, Inc. Phoenix and Gryphon crystallization robots,TTP Labtech Dragonfly liquid handler for crystal tray setup,Jansi UVEX UV/Vis microscope/imaging system,Stereomicroscopes (camera equipped, at room temperature and 4 degrees C),Incubators for temperature-controlled crystallization,Coordination of access to LS-CAT for Northwestern University users,CryoEM,JEOL 3200FS TEM equipped with in-column energy filter (omega filter), field emission gun capable of operating at 200 or 300 kV and Gatan K2 Summit Direct Electron Detector,JEOL 1400 with Gatan 4k x 4k Ultrascan CCD camera,Solarus Plasma Cleaner and Pelco easyGlow Discharge Cleaning System,Cressington 308R carbon coater,Gatan Cryoplunge 3 and FEI Vitrobot Mark IV,Gatan 626 cryoholders with 655 Turbo pump stations.Resources available Computational:50+ node cluster running Linux including several single- and multi-GPU nodes,7 Quad-core Intel Xeon 3.4GHz workstations (3D stereo equipped for visualization and model building) 3 Dual Quad-core Intel Xeon 3.5GHz workstations with GPU computing capabilities (3D stereo equipped for visualization, model building, and GPU computing),LTO6 writers for quick data backup,45 tape LTO6 system for continuous data backup,Over 200 Tb of disk storage including RAID systems,10 Gigabit fiber Ethernet connection to APS.Software Crystallography,CCP4 suite,PHENIX,SHARP,SOLVE,HKL2000,XDS,CryoEM,CryoSparc,Relion3,Leginon,cisTEM,Appion,NMR,CNS,FELIX,Aria Modeling, graphics, and simulations,COOT,Pymol,Chimera,APBS,GROMACS,AMBER,VMD/NAMD.

Proper citation: Northwestern University School of Medicine Structural Biology Core Facility (RRID:SCR_017952) Copy   

•   Source: SciCrunch Registry

https://www.unmc.edu/vcr/cores/vcr-cores/animal-behavior/index.html

Provides investigators with expertise, equipment, and space that is required to conduct innovative acoustic, behavioral, and cognitive research with focus on rigor, reproducibility, and maintaining the highest standards of animal welfare.

Proper citation: University of Nebraska Medical Center Animal Behavior Core Facility (RRID:SCR_018830) Copy   

•   Source: SciCrunch Registry

https://iee.psu.edu/labs/environmental-contaminants-analytical-laboratory

Laboratory is equipped with sample preparation and analysis equipment that support established analytical procedures including:Organic fluorine compounds-PFAS screening: EPA 1621; PFAS targeted and non-targeted analysis: EPA 537.1, EPA 1633; Pharmaceuticals and personal care products: EPA 1694; Agricultural chemicals: pesticides, herbicides-targeted and non-targeted analysis: various methods GC-MS/MS and LC-MS/MS; Volatile organic compounds: EPA 8260D (SW-846); Semivolatile organic compounds: EPA 8270E (SW-846); Dioxins and furans: EPA 23; Total petroleum hydrocarbons: EPA 8440; Microplastics and nanoplastics.

Proper citation: Pennsylvania State University Environmental Contaminants Analytical Laboratory Core Facility (RRID:SCR_026734) Copy   

•   Source: SciCrunch Registry

https://www.etsmtl.ca/laboratoires/lacime/equipement

Core provides equipment for the fabrication and advanced characterization of cyber-physical microdevices, particularly printed cyber-physical microdevices. Provide students and researchers with environment where engineers receive training with advanced skills in the analog, digital and mixed domains.

Proper citation: ÉTS Montréal LaCIME Scientific Platform Core Facility (RRID:SCR_028326) Copy   

•   Source: SciCrunch Registry