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https://icahn.mssm.edu/research/resources/deans-cores/transgenic-genome-editing

Core offers services from consultation until delivery of germline-confirmed genetically engineered mouse models (GEMMs). Uses genome editing tools such as CRISPR/Cas9 to rapidly generate GEMMs with diverse genome modifications such as humanization, large insertion, conditional knockout, base substitution and deletion. Animals produced in the CoRE are thoroughly genotyped by our comprehensive genotyping services. Supports model creation via the traditional transgenesis and the gene targeting in the embryonic stem cells. Other services provided by the CoRE include sperm cryopreservation, in vitro fertilization, rederivation and custom embryology supports.

Proper citation: Icahn School of Medicine at Mount Sinai Transgenic and Genome Editing Core Facility (RRID:SCR_027505) Copy   

•   Source: SciCrunch Registry

https://sites.ifi.unicamp.br/lamult/

Gleb Wataghin Institute of Physics (IFGW/UNICAMP) hosts a multi-user equipment facility, the LAMULT – an Open Facility-type Multi-user Laboratory that integrates various scientific instruments within single location.

Proper citation: State University of Campinas Gleb Wataghin Physics Institute LAMULT/IFGW Core Facility (RRID:SCR_027600) Copy   

•   Source: SciCrunch Registry

https://www.igmp.unibe.ch/forschung/core_facilities/translational_research_unit_tru_platform/index_ger.html

Core facility offers researchers access to histological services, tissue visualization, slide scanning, digital image analysis, and next-generation tissue microarrays. Our team processes more than 800 projects per year related to patient tissue, patient-related data, clinical studies, and animal models.

Proper citation: University of Bern Translational Research Unit Platform TRU Core Facility (RRID:SCR_027566) Copy   

•   Source: SciCrunch Registry

https://icahn.mssm.edu/research/genomics-institute/nanocore

Core Facility at the Icahn Genomics Institute (IGI) offers custom-made lipid nanoparticles and RNA technology to develop new therapeutics and nanomedicines.

Proper citation: Icahn School of Medicine at Mount Sinai RNA Nanocore Core Facility (RRID:SCR_027569) Copy   

•   Source: SciCrunch Registry

https://www.liverpool.ac.uk/clinical-directorate/clinical-research/biobanking/liverpool-university-biobank/

Core provides facilities including state of the art 2-D barcoded storage and LIMS, sample processing, histology, automated tissue microarray generation and spatial genomics profiling. Research Tissue Bank provides collection of both adult and paediatric biosamples, and is able to confer project-specific approval for their use.

Proper citation: Liverpool University Biobank Core Facility (RRID:SCR_027601) Copy   

•   Source: SciCrunch Registry

https://www.danforthcenter.org/our-work/core-facilities/data-science/

Core Facility provides infrastructure for high-performance computing and data storage (local and cloud). Services include access and training for use of high-performance computing resources, data analysis and visualization, data integration, statistical analysis, and image analysis.

Proper citation: Donald Danforth Plant Science Center Data Science Core Facility (RRID:SCR_027573) Copy   

•   Source: SciCrunch Registry

http://hpcf.umbc.edu

Facility maintains and administers the chip high performance computing cluster. The chip cluster is built from more than 150 machines featuring Intel CPUs and NVIDIA GPUs.

Proper citation: University of Maryland Baltimore County High Performance Computing Facility (RRID:SCR_027578) Copy   

•   Source: SciCrunch Registry

https://www.bidmc.org/research/core-facilities/clinical-research-coordinator-core

Clinical Research Coordinator Core is available to support and collaborate with investigators and their research teams in all phases of clinical research, providing services that include assisting with the organization, implementation and completion of clinical research studies.

Proper citation: Beth Israel Deaconess Medical Center BIDMC Clinical Research Coordinator Core Facility (RRID:SCR_027579) Copy   

•   Source: SciCrunch Registry

https://flowcytometry.utoronto.ca/

Core offers specialized services supported by research infrastructure, including flow cytometry, imaging mass cytometry (IMC), single-cell genomic sequencing, and dynamic live cell-culture imaging. Our facility is located in the Medical Sciences Building next to Queen’s Park, a central and convenient location for users across the Greater Toronto Area.

Proper citation: University of Toronto Centre for Immune Analytics Core Facility (RRID:SCR_027612) Copy   

•   Source: SciCrunch Registry

https://icahn.mssm.edu/research/advanced-genomics-technology

Core has built technology toolbox with access to and application of novel and existing methods in multitude of genomics technologies. These capabilities span bulk, single-cell, spatial, and in situ genomic sequencing methods, all of which are leveraged to generate complementary cross-platform, orthogonally validated datasets to foster novel discovery and advance clinical applicability using human cohorts and model systems

Proper citation: Icahn School of Medicine at Mount Sinai Center for Advanced Genomics Technology Core Facility (RRID:SCR_027572) Copy   

•   Source: SciCrunch Registry

https://icahn.mssm.edu/research/resources/deans-cores/biorepository-and-pathology

Core supports tissue and body fluid procurement, storage, and tracking from consented and de-identified collections. Pathologists responsible for procurement can be contacted for consultation to determine investigator requirements for human specimens in translational and basic research and then arrange procurement as feasible. Basic histology services include process, embed, and section fixed and frozen tissues (both animal and human), histochemistry, immunohistochemistry, immunofluorescence, in situ hybridization, laser capture microdissection, special stains for routine light microscopic evaluation. Offers full digital scanning capability with our quantitative and qualitative digital image analysis service (HALO), and support DNA/RNA/miRNA extraction from fluids and tissue specimens (both fixed and frozen) for downstream next generation sequencing and other applications.

Proper citation: Icahn School of Medicine at Mount Sinai Biorepository and Pathology Core Facility (RRID:SCR_027604) Copy   

•   Source: SciCrunch Registry

https://icahn.mssm.edu/research/resources/deans-cores/metabolomics

Core provides mass-spectrometry solutions for small-molecule research. Supports experimental design, ensuring proper handling, appropriate controls, and adequate statistical power, and then executes analyses on Thermo Orbitrap IQ-X and Agilent 6495D LC/MS systems and an Agilent 5977C GC/MS system. Using validated methods annotated against a library of 1,000+ compounds, we maximize metabolite and small-molecule coverage. We also offer untargeted profiling for biomarker and novel metabolite and lipid discovery, as well as stable-isotope tracing for measuring substrate utilization. Results are delivered with custom informatics and statistical interpretation for faster, more approachable insights.

Proper citation: Icahn School of Medicine at Mount Sinai Metabolomics Core Facility (RRID:SCR_027540) Copy   

•   Source: SciCrunch Registry

https://gladstone.org/science/stem-cell-core

Core offers a fully functional tissue culture facility with specialized instruments, media, reagents, cell lines, and expertise for new or established researchers to perform cutting-edge stem cell research. In addition, our core provides comprehensive human induced pluripotent stem (iPS) cells related training, consultations, and standard and customized scientific services, including derivation of iPS cells, differentiation of iPS cells and genome editing in iPS cells to stem cell researchers.

Proper citation: Gladstone Institutes Stem Cell Core Facility (RRID:SCR_027543) Copy   

•   Source: SciCrunch Registry

https://www.clf.stfc.ac.uk/Pages/Octopus-new.aspx

Provides expert advice and guidance for collaborative research projects involving the use of fluorescence and electron microscopy. Access to advanced fluorescence and electron microscopes for external users after a peer-review process.

Proper citation: Science and Technology Facilities Council Octopus Core Facility (RRID:SCR_027542) Copy   

•   Source: SciCrunch Registry

http://www.gwgenomics.org

Genomics Core team has expertise in bacterial genomics, computational biology, infectious disease, HIV, population and conservation genetics. Offers NGS services. Capable of supporting projects at any stage, from planning to sample processing to sequencing. keith crandall

Proper citation: George Washington University Milken Institute School of Public Health Genomics Core Facility (RRID:SCR_027546) Copy   

•   Source: SciCrunch Registry

https://pmflow.ca/

Core offers services in Analytical Flow Cytometry, Fluorescence Activated Cell Sorting, consultation and data analysis. Staff provides training, assisted acquisition, consultation, and data analysis upon request.

Proper citation: University Health Network Princess Margaret Flow Cytometry Core Facility (RRID:SCR_027537) Copy   

•   Source: SciCrunch Registry

https://genomique.iric.ca/

Facility offers services, combining expert guidance and technologies including Sanger Sequencing, Next-Generation Sequencing, Single-Cell Sequencing, qPCR, Quantity and Quality of DNA and RNA measurement.

Proper citation: University of Montreal Institute for Research in Immunology and Cancer Genomics Platform Core Facility (RRID:SCR_027674) Copy   

•   Source: SciCrunch Registry

https://www.rcd.tntech.edu/

Core empowers students, faculty, and staff across all disciplines by providing the tools, training, and equipment for advanced computing for more robust, reproducible research with reduced time to results. Manages the campus cluster, and also facilitate access to larger federally-funded clusters at zero cost. Provided data transfer and network performance monitoring services enable researchers and collaborators to move data quickly.

Proper citation: Tennessee Tech University Research Computing and Data Core Facility (RRID:SCR_027555) Copy   

•   Source: SciCrunch Registry

https://www.ladydavis.ca/en/about/core-facilities/flow-cytometry/

Core provides complete flow cytometry analysis and cell sorting services in terms of experimental design, instrumentation, training, technical assistance and scientific guidance from sample preparation to publication.

Proper citation: Lady Davis Institute Flow Cytometry Core Facility (RRID:SCR_027644) Copy   

•   Source: SciCrunch Registry

https://amdl.uhnresearch.ca/

AMDL is a clinical CAP/CLIA accredited molecular diagnostics laboratory at the Princess Margaret Cancer Centre. Supports clinical trials and translational research projects requiring clinical-grade (CAP/CLIA) molecular testing at Princess Margaret Cancer Centre. AMDL works closely with Molecular Diagnostics lab in Toronto General Hospital to transition protocols into clinical tests.

Proper citation: University Health Network Advanced Molecular Diagnostics Laboratory Core Facility (RRID:SCR_027525) Copy   

•   Source: SciCrunch Registry