Tools   Select Another Resource Report Type

https://www.umass.edu/ials/core-facilities/electron-microscopy

EM Core Facility offers instrumentation and training for range of Electron Microscopy applications. Instrumentation includes Thermofisher Tundra cryo-TEM, Tecnai T12 TEM, Magellan 400 SEM, JEOL JEM-2200FS, Vitrobot Mark IV, (cryo)microtomes, and other auxiliary equipment.

Proper citation: University of Massachusetts Amherst Electron Microscopy Core Facility (RRID:SCR_027853) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/cancer/research/shared-resources/biostatistics/

Core provides biostatistical review of grant applications, offering clear, practical feedback on feasibility and statistical rigor to investigators and review panels. We support investigators across the research lifecycle, from grant proposal development and clinical protocol design to laboratory, animal, and epidemiologic study planning. Services also include short-term consultations, study monitoring, data analysis, manuscript preparation, and responses to peer review.

Proper citation: Augusta University GCC Biostatistics Core Facility (RRID:SCR_027784) Copy   

•   Source: SciCrunch Registry

https://fralinlifesci.vt.edu/core-services/flow-cytometry.html

Facility offers traditional data acquisition, analysis, and cell sorting as well as imaging cytometry. Provided equipment includes: BD FACSAria Fusion: A cell sorter that can also be used as an analyzer, it is equipped with 488nm, 640nm, and 405nm excitation sources and is equipped to analyze up to fifteen parameters simultaneously. The Fusion is capable of processing up to 70,000 events per second and sorting up to four different cell populations at once. It is also equipped with an Automatic Cell Deposition Unit (ACDU) that allows sorting of cells into plates or onto slides; Amnis ImageStream MarkII: this imaging cytometer combines the speed and objectivity of flow cytometry with the detailed imagery of microscopy to allow you to objectively and quantitatively describe biological processes based on cell size, shape, and fluorescence location, texture, and signal intensity.This open platform enables new methods of research and improves traditional flow and imaging based applications. It is equipped with 405nm, 488nm, and 642nm excitation sources and is able to analyze up to twelve parameters simultaneously. It has 20X, 40X, and 60X objective lenses and Enhanced Depth of Field technology. It can process several thousand cells per second.

Proper citation: Virginia Tech Flow Cytometry Core Facility (RRID:SCR_027816) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/antitumor-assessment

Core provides support for early discovery and in vivo testing of antitumor detection and therapeutic agents. Provides resources, professional and technical expertise, and advisory services related to evaluation of agents with potential diagnostic or therapeutic activity. ATA Core works closely with investigators to establish preclinical models, including Patient-Derived Xenograft (PDX) and Patient-Derived Organoid (PDO) models, for the design and execution of pharmacokinetic (PK), toxicity, and in vivo efficacy studies. Assists investigators in determining the best formulation, administration route, and treatment schedule for each new compound, either alone or in combination with other agents.

Proper citation: Memorial Sloan Kettering Cancer Center Antitumor Assessment Core Facility (RRID:SCR_027795) Copy   

•   Source: SciCrunch Registry

http://pcl.tamu.edu

Core provides instrumentation, systems, software, technical expertise and training for the application of novel protein and molecular biology technologies. Provides training and expertise. Offers protein and amino acid services.

Proper citation: Texas A and M University Protein Chemistry Laboratory Core Facility (RRID:SCR_027711) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/genome-editing-screening

Core Facility provides functional genomics, highthroughput screening (HTS), and high-content screening (HCS) services toward the discovery of novel cancer targets and elucidation of complex, aberrant cellular pathways. Offers assistance and training in range of cloning, customized library design, lentivirus production, assay development, screening, and image analysis considerations to assist researchers in harnessing these powerful target identification tools and drug screening methodologies. Offers CRISPR-mediated transcriptional activation/interference (CRISPRa/CRISPRi) technologies combined with lentivirus delivery systems, customized stable isogenic cell line generation (knockout, HDR-directed knock-in, knockdown, base editing, and prime editing) toward the generation of unique cancer cell line models.

Proper citation: Memorial Sloan Kettering Cancer Center Genome Editing and Screening Core Facility (RRID:SCR_027799) Copy   

•   Source: SciCrunch Registry

https://www.medschool.umaryland.edu/cibr/core/em/

Core is part of the Center for Innovative Biomedical Resources (CIBR) and is located on the 6th floor of Howard Hall. All services, instrumentation, and training courses are available to anyone, academic or private users, with an interest in electron microscopy.EMCIF services are managed by iLab core facility management program. New users must register in iLab to access instrument and EMCIF services.

Proper citation: University of Maryland School of Medicine Baltimore Electron Microscopy Core Imaging Facility (RRID:SCR_027760) Copy   

•   Source: SciCrunch Registry

https://www.immunology.pitt.edu/core-facilities/mouse-embryo-services-mes-core

Core provides services including generation of gene editing mice, transgenic mice, ES cell microinjection into blastocysts to create germline competent chimera, cryopreservation and long-term storage of mouse sperm/embryos, recovery of mouse lines from cryopreserved germplasm, in vitro fertilization for mouse line rescue and re-derivation of pathogen free mouse strains.

Proper citation: University of Pittsburgh Mouse Embryo Services Core Facility (RRID:SCR_027775) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/proteomics-metabolomics-core

Core provides mass spectrometric sequencing and quantitation of peptides and proteins to support basic, translational, and clinical research programs at MSK. Utilizes modern high-resolution mass spectrometry and nanoscale liquid chromatography in conjuction with biochemical processing of samples with the end goal of determining the identity, relative abundance, and presence of post translational modifications from purified components, cell lysates, tissues, and select fluid such as cerebral spinal fluid. Advice is provided by the Core staff to facilitate the design, execution, and analysis of experiments.

Proper citation: Memorial Sloan Kettering Cancer Center Proteomics and Metabolomics Core Facility (RRID:SCR_027811) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/animal-imaging

Core offers suite of animal imaging modalities, including MRI, PET, CT, SPECT, and ultrasound, all commonly used in clinical settings, enhancing the likelihood that findings in animal models will be translatable to human patients. Key instruments include 7.0T and 9.4T MRI systems, PET/MR, PET/CT, SPECT/CT, and advanced ultrasound systems, alongside specialized equipment including a small animal radiation therapy unit and variety of ancillary tools for advanced imaging analysis.

Proper citation: Memorial Sloan Kettering Cancer Center Animal Imaging Core Facility (RRID:SCR_027810) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/structural-biology

Core provides expertise, advanced equipment, and leading software to support structural investigations. Core maintains equipment, including Krios cryogenic electron microscopes and computational resources for data collection, processing, and structure determination. These resources include graphical workstations and high-performance Linux cluster, supporting the analysis of large proteins, complexes, and macromolecular assemblies.Core has access to synchrotron beamlines and cryo-EM facilities.Provides training and assistance to users, collaborates with non-structural MSK groups on projects involving macromolecular crystallization and structure determination, offers modeling expertise and guidance, enabling labs to use available structural data in experiment design and interpretation.

Proper citation: Memorial Sloan Kettering Cancer Center Structural Biology Core Facility (RRID:SCR_027809) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/molecular-cytology

Core delivers specialized histology, microscopy, and cytogenetics services for detection in situ (cells, tissue sections, organoids, and whole mounts) of biomarkers (proteins, glycoproteins, lipids, nucleic acids) and molecular processes in normal and pathological conditions. Performs comprehensive antibody validation on cells and tissues, trains investigators in basic staining principles and assists with experimental assay design and downstream analysis. Core maintains four whole-slide scanners and provides support for quantitative whole-slide analysis. Microscopy and dedicated image analysis staff provide support for simple or complex analysis pipelines.

Proper citation: Memorial Sloan Kettering Cancer Center Molecular Cytology Core Facility (RRID:SCR_027802) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/radiochemistry-molecular-imaging-probes

Core functions include cancer biology, medicine, chemistry, physics, radiochemistry, pharmacology, and engineering.Provides investigators with radionuclides and to incorporate these radionuclides into radiolabeled diagnostic and/or therapeutic pharmaceuticals for both basic research investigations and patient formulations. Core provides services: Cyclotron Radionuclide Production Section, Radiolabeling Section, Development and Clinical Translation Section, and Hyperpolarized Magnetic Resonance Section.

Proper citation: Memorial Sloan Kettering Cancer Center Radiochemistry and Molecular Imaging Probes Core Facility (RRID:SCR_027806) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/stem-cell-research-facility

Core stocks, characterizes, and distributes human pluripotent stem cell (hPSC) lines. Performs variety of hPSC-related applications for the stem cell community at SKI and beyond. We are a part of the Starr Foundation-funded Tri-Institutional Stem Cell Initiative that provides shared stem cell expertise and resources among Memorial Sloan Kettering, Weill-Cornell, and Rockefeller University.

Proper citation: Memorial Sloan Kettering Cancer Center Stem Cell Research Core Facility (RRID:SCR_027808) Copy   

•   Source: SciCrunch Registry

https://www.mskcc.org/research/ski/core-facilities/research-pharmacy

Core is a full-service facility that prepares agents developed by MSK researchers to be used as investigational drugs in preclinical or clinical studies. The Core comprises three principal groups: the Pharmaceutical Product Facility (PPF) for drug formulation/stability and preparation; the Clinical Grade Production (CGP) Facility for bulk product manufacturing, purification, and vialing; and the Pharmacy Investigational Drug Service (PIDS), which develops, procures, prepares, and validates the preparation, packaging, and distribution of investigational drugs for clinical use. Core services include: formulation, analysis, and evaluation of drug release rates; prediction of interactions; and determinations of compatibility and physical stability of medications. Based on the expertise of the RP Core, MSK has been able to bring into early-phase clinical trials multiple types of pharmacologic agents, including traditional small molecules, radiopharmaceuticals, and vaccines.

Proper citation: Memorial Sloan Kettering Cancer Center Research Pharmacy Core Facility (RRID:SCR_027807) Copy   

•   Source: SciCrunch Registry

https://mcity.umich.edu/m-air/

Core for testing advanced air mobility (AAM), focusing on drones and electric aircraft, especially Beyond-Line-of-Sight (BVLOS) autonomous flight, to accelerate innovation and commercialization in the industry. It serves as a real-world "skyway" for researchers and companies to test new technologies like electric vertical takeoff and landing (eVTOL) aircraft, support Michigan Medicine's air transport, and foster aerospace startups, building on U-M's existing robotics and autonomous vehicle testing facilities.

Proper citation: University of Michigan M-Air Core Facility (RRID:SCR_027859) Copy   

•   Source: SciCrunch Registry

https://research.bidmc.org/zebrafish-core/about

Core Facility is a 3,000+ fish tank facility, located in the Slosberg-Landay building, equipped with 48 racks which hold standard sized adult zebrafish tanks, three-rack nursery space for larval fish, and quarantine space containing two stand-alone housing systems. Wild-type lines are maintained inhouse for shared use. Wet lab space is available for breeding and line maintenance; core staff and facility-associated technicians perform daily feeding. The core includes a dedicated procedure room for embryo manipulation.

Proper citation: Beth Israel Deaconess Medical Center BIDMC Zebrafish Research Core Facility (RRID:SCR_027756) Copy   

•   Source: SciCrunch Registry

https://www.augusta.edu/sph/survey-center/

Core offers services including statistical analyses, grant applications, prep for manuscript publications, etc.

Proper citation: Augusta University Statistical Consulting Center Core Facility (RRID:SCR_027755) Copy   

•   Source: SciCrunch Registry

http://mmcri.org/ns/?page_id=221

Core provides viral vector services dedicated to development and production of viral vectors for angiogenesis, stem cell and regenerative medicine and clinical renal research. Viral vectors are produced in dedicated BL2 facility within MMCRI building. Vector systems currently being used include adenovirus, retrovirus and lentivirus. Services Available:Transfection and transduction of gene-specific viral DNA provided by principal investigators;Small, large and custom scale production of adenovirus;retrovirus and lentivirus (2nd and 3rd generation packaging);TCID50 titration of adenovirus;Titration of retrovirus and lentivirus (fluorescence marker or antibiotic resistance);Test for replication competent virus (RCV) in lentivirus preparations.

Proper citation: Maine Medical Center Research Institute Viral Vector Core Facility (RRID:SCR_017882) Copy   

•   Source: SciCrunch Registry

http://mass-spec.stanford.edu

Core mass spec and proteomic services include open access lab for trained users with GC/MS, LC/MS, high resolution LC/MS, and MALDI-TOF instruments, help with intact protein analysis, targeted quantitation, drug discovery support, pathway analysis, protein interactions, FFPE tissue analysis, both labeled and label-free proteomics, and more. Please contact SUMS to discuss these and other custom projects including new application development.

Proper citation: Stanford University Vincent Coates Foundation Mass Spectrometry Laboratory Core Facility (RRID:SCR_017801) Copy   

•   Source: SciCrunch Registry