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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Centralized, coordinated imaging facility.Provides electron and ion beam analytical microscopy instruments.Full service facility from extensive sample preparation laboratories to image processing tools and support.
Proper citation: Ohio State University Center for Electron Microscopy and Analysis Core Facility (RRID:SCR_021294) Copy
https://mcgill.ca/cftrc/platforms/primary-airway-cell-biobank-pacb
Nonprofit facility providing researchers worldwide with standardized, high-quality primary airway cells from normal and large variety of airway diseased donors with different genetic backgrounds, are essential for improving our understanding of CF and other respiratory diseases and for translational research to develop new therapeutic agents.The PACB is certified by the UBC Office of Biobank Education and Research Biobank Certification Program.
Proper citation: McGill University Primary Airway Cell Biobank Core Facility (RRID:SCR_020998) Copy
https://sites.google.com/ucsc.edu/ucsccrisprcore/home
Facility that provides CRISPR services and expertise to facilitate study of gene function. Services include project consultation, sgRNA design and cloning, lentivirus production, custom CRISPR cell line generation and genome wide CRISPR screen.
Proper citation: University of California at Santa Cruz CRISPR Core Facility (RRID:SCR_021207) Copy
https://www.feinberg.northwestern.edu/sites/cam/
Core offers instrumentation and services for study of biological processes at whole animal, tissue, cellular and subcellular levels. This includes light microscopy, electron microscopy and image analysis. Light microscopy offerings include super resolution microscopy (MINFLUX, STED, NSPARC, SORA), fluorescent laser scanning and spinning disk microscopy, fluorescent lifetime imaging, automated high throughput tissue cytometry, atomic force microscopy, laser capture microdissection, mutliphoton imaging, and whole animal bioluminescent and fluorescent imaging. Electron microscopy includes sample prep and imaging for TEM, SEM, platinum replicas, immuno gold and CLEM. We also provide microinjection equipment, chambers for stable live cell observation, and anesthesia equipment. CAM provides training on numerous different instrument platforms, consultation on experiment design, as well as digital image processing and image analysis.CAM is one of two Nikon Imaging Centers in the US, allowing us access and excellent support from Nikon to develop innovative solutions for the cutting edge imaging needs of users.
Proper citation: Northwestern University Feinberg School of Medicine Center for Advanced Microscopy and Nikon Imaging Center Core Facility (RRID:SCR_020996) Copy
Center composes network of core imaging facility locations for advanced optical imaging and basic electron microscopy located within the AHC/Medical School (1-151 Jackson Hall, Minneapolis) and College of Biological Sciences (23 Snyder Hall, St. Paul) on the University of Minnesota Twin Cities Campus.UIC cores serve internal and external research clients in design of imaging experiments, choice of and training on suitable imaging systems, and subsequent image processing, visualization and analysis.Provides advanced imaging systems including macro spectral confocal microscopy,wide-field light and fluorescence microscopy, spinning disk confocal, laser-scanning confocal microscopes, multi photon/Second Harmonic Generation microscopes, total internal reflectance microscope, laser capture micro-dissection, live cell imaging systems, scanning and transmission electron microscopy, whole animal fluorescence, bioluminescence and chemiluminescence imagers, gel, print and film scanners,poster printers, full sample preparation capabilities.
Proper citation: University of Minnesota University Imaging Centers Core Facility (RRID:SCR_020997) Copy
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on December 11, 2025. Interdisciplinary team of engineers and scientists, representing fields of physics, mathematics, and computer science, that combine their expertise in areas such as microscopy, lasers, optoelectronics, applied mathematics, image and signal processing, computer graphics, computer vision, statistics, software engineering, and biophysics, to develop imaging approaches for cell biology. Pioneers in high-resolution 3D imaging using wide-field fluorescence microscopy together with digital image deconvolution, and image visualization and quantitative analysis techniques, especially as applied to statistical analysis of images to determine co-localization of fluorescence markers inside cells.Research includes development and application of light microscopy and imaging in cell biology and biophysics.Developed TESM microscope that combines Total internal reflection fluorescence (TIRF) with Epi-fluorescence Structured illumination to provide new views of trafficking in near plasma membrane domain of cells.Provides custom-built, ultra-high-speed microscope system for imaging dynamics of intracellular calcium channel events, called calcium sparks, that are being found to regulate expanding array of cellular processes. Provides two photon fluorescence microscope for looking deep inside tissue, completing range from molecule to organism. Areas of ongoing technology research include high-speed, high-resolution imaging of live cells and tissues, novel image processing approaches, high-performance computing, and computer graphics.
Proper citation: University of Massachusetts Medical School Biomedical Imaging Group Core Facility (RRID:SCR_021201) Copy
The MIC Live Imaging and Physiology Core is a division of the Microscopy and Imaging Center of the UVM Larner College of Medicine. The Live Imaging and Physiology Core provides a wide range of imaging techniques mainly for live-cell, live-tissue and in-vivo preparations. We maintain a Noran/Prairie Technologies OZ LSCM (laser scanning confocal microscope), a DeltaVision RT restoration microscopy system, a Zeiss/BioRad 2100 dedicated multiphoton LSCM, a Zeiss LSM 7 MP dedicated multiphoton LSCM, a Nikon TIRF (total-internal reflection fluorescence) system, a Nikon/Yokogawa CSU-W1 spinning disk microscopy system, a PTI monochromator system, and a Nikon SMZ-1500 fluorescence stereoscope. Patch-clamp electronics are available for use on most microscope systems, and each system has an integrated perfusion setup.
Proper citation: University of Vermont Larner College of Medicine Microscopy Imaging Center Live Imaging and PhysiologyCore Facility (RRID:SCR_021289) Copy
https://research.utexas.edu/cbrs/cores/bms/
Proteomics and Metabolomics services and collaborative efforts are provided at Biological Mass Spectrometry Facility. We use high resolution Orbitrap mass spectrometers with UPLC at high flow for metabolomics and nanoUPLC for proteomics work. We have Bruker Autoflex for self service MALDI. Our proteomics services are protein ID, quantitation, and modification analysis, with fractionation for deeper coverage and de novo sequencing of mAbs available. We collaborate for customized projects. We have untargeted metabolomics for quantitative or qualitative analysis of extracted metabolites using C18 column.
Proper citation: University of Texas at Austin Biological Mass Spectrometry Proteomics Core Facility (RRID:SCR_021728) Copy
https://www.stowers.org/technology/genome-engineering
Core supports genome engineering using CRISPR technology. Provide services to generate knockouts, insertions, deletions, and point mutations in various organisms. Services for genome engineering include guideRNA design, homology-directed repair template design, production of modified mammalian cell lines, preparation of reagents for delivery to embryos, and mutation detection by targeted deep sequencing. Pooled screening is also coordinated and supported by our team.We acquire, prepare, and validate pooled libraries as an Institute resource. In coordination of our pooled screen workflow, we work with other teams to track the progress of these projects. Once resulting cell populations from the screen are delivered, our team does genomic DNA purification, target amplification, and preparation for NGS. We now offer a TAIL-PCR service to identify the location of random integration events. We have successfully identified locations in killifish, fly, zebrafish, and sea anemone.Team is responsible for maintaining and distributing clone and vector collections for the Institute.
Proper citation: Stowers Institute for Medical Research Genome Engineering Core Facility (RRID:SCR_021729) Copy
Provides short training courses to in service public health practitioners and professionals.Offers teaching, research, and policy advice in public health in Pakistan.
Proper citation: Islamabad Health Services Academy Core Facility (RRID:SCR_021209) Copy
https://www.biotech.cornell.edu/core-facilities-brc/facilities/genomics-facility
Full Service DNA Sequencing and Genotyping facility. Offers Sanger,Fragment Analysis, Illumina, RT and Digital PCR, Single Cell, large projects, sample/library prep and QC.Houses state of the art instruments for all your sequencing needs including, capillary DNA analysis, single cell applications, long read capabilities. We also provide many instruments that can be operated by you for sample preparation and quality control of all sample types.
Proper citation: Cornell University BRC Genomics Core Facility (RRID:SCR_021727) Copy
https://www.unmc.edu/cctr/resources/biobank/index.html
Nebraska Biobank is made up of residual blood samples from volunteer patients. Serum, Plasma, and DNA are recovered from the consented samples and stored for future research studies.Deidentified data from the Electronic Health Record (EHR) such as age range, diagnosis, and medications are linked to the stored samples. Any faculty member from the University of Nebraska system may request samples from the biobank for their research projects but all requests are subject to feasibility and scientific merit review.Offers sample management services to investigators for clinical trials and registries.
Proper citation: University of Nebraska Medical Center Nebraska Biobank Core Facility (RRID:SCR_021024) Copy
https://ibsc.ucsc.edu/facilities/microscopy
Core facility affiliated with Institute for Biology of Stem Cells.Provides imaging instrumentation to biology research community including personalized assistance on various aspects of imaging.Offers assistance in experimental design,training on shared microscopes, image visualization and image analysis.
Proper citation: University of California at Santa Cruz Life Sciences Microscopy Center Core Facility (RRID:SCR_021135) Copy
https://wcmc.corefacilities.org/service_center/show_external/5753/human_immune_monitoring_core_himc
Core provides technology platforms and services for single cell, in situ, and multiomic analysis for cutting edge immunology research and clinical studies to help make impactful discoveries and develop improved treatments for human diseases. Services include Spectral flow cytometry (Cytek Aurora), Imaging mass cytometry (Fluidigm Hyperion), CyTOF mass cytometry (Fluidigm Helios).
Proper citation: Cornell University Weill Medical College Human Immune Monitoring Core Facility (RRID:SCR_021669) Copy
https://www.clemson.edu/centers-institutes/light-imaging/
Core light microscopy facility located on main campus of Clemson University. Offers access to multiple Leica Microsystems instruments, including SP8X LIGHTNING confocal with STED,SPE confocal, DMi8 widefield/TIRF/GSD system,THUNDER model organism imager, LMD6500, M125 stereoscope, and DM750P polarized light microscope.We also house Olympus LEXT OLS4100 optical profiler, GE InCell 2500HS high content screener, and Biorad S3e cell sorter. Offers assistance with equipment selection, image analysis, and sample preparation. Offers prepared slides for 4 color fluorescence imaging and can also prepare custom slides.
Proper citation: Clemson University Light Imaging Core Facility (RRID:SCR_020973) Copy
https://ibsc.ucsc.edu/flow-cytometry-facility/
Facility offers multicolor cell analysis by BD LSRII cell analyzer and single cell sorting by BD Biosciences FACS Aria cell sorter. Provides user training for self-op use of BD FACS LSRII analyzer 3-laser and Self-op and Assisted sorting on BD FACS Aria IIU 5-lasers.
Proper citation: University of California, Santa Cruz IBSC Flow Cytometry Core Facility (RRID:SCR_021149) Copy
https://www.crchudequebec.ulaval.ca/en/services/proteomics/about-us/
Proteomics platform offers sample preparation, protein identification, post-translational modification (PTM) protein analysis, protein quantification (Label Free, Label based and tarteted proteomics by MRM or PRM) by mass spectrometry and statistical or functional bioinformatic analyses.
Proper citation: Laval University Proteomics Platform Core Facility (RRID:SCR_021025) Copy
https://research.med.psu.edu/core-facilities/genome-sciences/
Provides consultation, instrumentation and services in genomic, epigenomic and transcriptomic studies, analysis of candidate SNPs and mRNAs to whole genome, exome, epigenome and transcriptome sequencing. Services are also available for variety of study designs extending from few laboratory samples to large clinical projects involving hundreds or thousands of samples.Bioinformatics service is available for data analysis.Facility receives either tissue, DNA/RNA or customer generated NGS libraries. Samples are processed based on agreement reached during consultations on design of experiment.
Proper citation: Penn State College of Medicine Genome Sciences Core Facility (RRID:SCR_021123) Copy
Offers microscopy imaging services to both internal and external users in the greater Boston area. The facility is equipped for live cell imaging, laser scanning confocal and super resolution microscopy. Common sample types imaged in the facility are live and fixed bacteria, biofilms, embedded soft tissue, cleared tissue, and mineralized tissue and samples can be labelled or label free. One area of expertise is imaging many fluorophores simultaneously using spectral imaging and linear unmixing. In addition to instrument training, we can also provide advice for sample preparation and image analysis. In some cases, we are able to provide full-service imaging for customers.
Proper citation: Forsyth Institute Advanced Microscopy Core Facility (RRID:SCR_021121) Copy
https://medicine.tamu.edu/imil
Core supports research progress and grant development by encouraging researchers to explore advanced imaging modalities and to incorporate them into their existing research programs.Provides technical expertise and cutting edge microscope systems to support research of faculty and staff of Texas A&M University Health Science Center, Texas A&M University, and all other campuses.IMIL includes six microscopy rooms, supporting facilities, and image processing station.Technical staff is available to train and assist with design, implementation, and analysis of experiments as well as assist in troubleshooting.
Proper citation: Texas A&M Health Science Center Integrated Microscopy and Imaging Laboratory Core Facility (RRID:SCR_021637) Copy
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