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http://www.coriell.org/research-services/biobanking/overview/

Dr. Lewis Coriell''s pioneering techniques for characterizing, freezing, and storing cell cultures in liquid nitrogen constitute one of the greatest contributions to modern human research. Today, the Coriell Biobank is regarded as the most diverse collection of cell lines and DNA available to the international research community. In addition to these high-quality biospecimens, Coriell also maintains tissue, plasma, serum, urine, and cerebrospinal fluid. Few organizations have the history of innovations in repository science that have been developed and implemented at Coriell. For nearly 60 years, Coriell has set the standard in biobanking services, including the experimental design, collection, processing, distribution, cryogenic preservation, and information management of human biomaterials used in research. By developing and maintaining biorepositories as national and international resources for the study of human diseases, aging, and neurological disease, Coriell is committed to providing the scientific community with well-characterized, cell cultures and DNA preparations, annotated with rich phenotypic data. The Coriell Biobank has allowed both Coriell scientists, and research investigators around the world, to advance research programs in genetics and cell biology. Since the first repository ����?����������?? a National Institutes of Health collection ����?����������?? was established at Coriell in 1964, hundreds of thousands of cell lines and DNA samples have been distributed to researchers in 64 countries; more than 7,000 peer-reviewed papers have been published citing almost 12,000 biospecimens from the Coriell Biobank. Coriell''s repositories provided support to the Human Genome Project, a worldwide program to map the entire human genome, and to the International HapMap Project, a project providing an efficient tool to identify disease-causing genes. Coriell offers almost 60 years of experience in the banking, cryopreservation, and fail-safe storage of cell lines, DNA, and other biomaterials. The renowned Coriell biobank is ISO9001:2008 certified. Our highly-trained technicians, supported by on-staff scientists with expertise with genomics, provide proficient, individualized care for your biospecimens. From specimen collection, processing, quality control, enterprise level data, and inventory management, through rapid retrieval of specimens and secure shipment, Coriell offers full-service biorepository services.

Proper citation: Coriell Biobank (RRID:SCR_010562) Copy   

•   Source: SciCrunch Registry

http://www.virginhealthbank.com/

Virgin Health Bank was developed to meet the needs of families in the UK who are considering banking their baby''s cord blood stem cells and want the support of an ethically motivated cord blood bank committed to delivering high quality service. We provide an HTA licensed state-of-the-art processing and storage service for parents who would like to store the stem cells from their newborn baby''s umbilical cord blood. * Uniquely we offer you a choice of cord blood banking services; your family can choose from our Family Banking service or our Community Banking service. * We empower UK families to make informed decisions about storing their baby''s cord blood stem cells by providing them with accurate and honest information and do not pressure them into buying our services. * Stem cells from our cord blood bank have been used for transplantation by Doctors in the UK''s National Health Service and we''re proud to operate under a license issued to us by the Human Tissue Authority. If you choose our Family Banking service or our Community Banking you will be informed once your baby''s stem cells have been safely collected, tested and stored. If you have chosen our Community Banking service then we will separate the unit into two elements. Your family''s portion of the unit will be treated in exactly the same way as those in our Family Banking service. It is your family''s and nothing will be done to it or with it without your express written permission. We will test the cells to determine the HLA type. Information on the element of the stem cell unit that you have chosen to donate to the community will be included on an international registry alongside those of others. The registry provides real hope to families and individuals afflicted with diseases where cord blood stems cells are approved for treatment. Doctors use this registry as a resource from which they can request donated cord blood for treatments. These are used in circumstances where a tissue typed, donated unit is required rather than the patient''s own. By contributing to the development of this international registry you maximize the availability of stem cells for the treatment of your family and others. By helping others you also help yourself by helping to develop a community stem cell bank from which your own family may benefit.

Proper citation: Virgin Health Bank (RRID:SCR_008719) Copy   

•   Source: SciCrunch Registry

http://www.stemcure.com/stemcure.php?page=tissue-banking

Stunning scientific discoveries have opened the possibilities for us to preserve our unaltered youth and healthy genome almost indefinitely. To do this, we propose to our clients to allow us to isolate and cryopreserve a small piece of tissue from their body in our unique tissue bank via a simple skin biopsy procedure. Our methods provide 100% assurance that the tissues we preserve will remain viable, healthy and young. We guarantee that these tissues will correspond to the age and physical status from the time when they were collected and can be preserved for many decades to come. In that way we strive to accomplish mankind''s most important dream ������?? to stop the hands of time and reduce the effects of aging. We will bring to a standstill the genetic program that is encoded in our cells that cause us to age and grow older. What is unique about this procedure, from a biological perspective, is that even as a person continues to live longer and get older, at the same time, part of his body remains invariably young. This well-preserved critical piece of tissue contains all the vitally important genetic material that harnesses the potential for invigorating one''s health. It will play an essential role in the rehabilitation and rejuvenation of human beings in the future. Recent studies have shown that certain parts of our skin are the most optimal material to be used for our program. For this purpose we utilize fibroblasts, the cells of the connective tissues located at the bottom side of our epidermis. In order to properly extract fibroblasts from our skin we have to perform a basic skin biopsy procedure. If you decide to participate in our program, StemCure will send to you the standard Tissue Collection Kit. This Kit contains detailed instructions for how your doctor should perform the biopsy procedure, as well as all the necessary components for the collection and transportation of a biopsy sample. StemCure will immediately start processing your biopsy samples once they arrive by overnight shipment to one of our laboratory facilities. We perform this very elaborate procedure because we understand perfectly well that our ultimate goal is not just the preservation of your tissue samples, but rather their subsequent utilization for the production of embryonic stem cells, which is the next stage of our program. Before subjecting the samples of your tissue to freezing, we will use the skin tissue to initiate the growth of the cell culture. After initial testing of the cell culture for viability and physiological activity, we will start its preparation for cyropreservation. StemCure will do everything in its power to ensure that the ������??Youth Genome������?? of our clients is safely protected and will remain a viable source for their healthy disease-free future.

Proper citation: StemCure Tissue Banking (RRID:SCR_010538) Copy   

•   Source: SciCrunch Registry

http://www.med.upenn.edu/molecular/core_culture.shtml

Core facility that maintains a centralized repository of cells and reagents pertinent to digestive, liver and pancreatic disease research. It also provides training for labs in new cell culture (2D and 3D) techniques.

Proper citation: University of Pennsylvania Center for Molecular Studies in Digestive and Liver Diseases Cell Culture Core (RRID:SCR_015621) Copy   

•   Source: SciCrunch Registry

http://livercenter.ucsf.edu/cell-biology-core

Core whose purpose is providing primary and immortalized liver cells for experimental use as well as other material such as human liver cells, primary hepatocytes, and immortalized cell lines.

Proper citation: UCSF Liver Center Cell Biology Core (RRID:SCR_015600) Copy   

•   Source: SciCrunch Registry

http://www.uchicagoddrcc.org/research-cores/integrated-translational-research-core

Core that serves as both a central repository for all the samples and data shared by the other cores and a catalyst for interdisciplinary research.

Proper citation: University of Chicago Digestive Diseases Research Core Center Integrated Translational Research Core (RRID:SCR_015606) Copy   

•   Source: SciCrunch Registry

http://rdocdb.nimh.nih.gov

A database that houses human subjects data related to mental health research. Data from 691 subjects are shared in RDoCdb and data from 100,500 subjects are shared in the NIMH Data Archive. Users can plan for data submission, share data, query data, or share their results related to a publication or finding.

Proper citation: RDoCdb (RRID:SCR_013796) Copy   

•   Source: SciCrunch Registry

https://med.stanford.edu/lucasmri.html

Biomedical technology research center that develops innovative technologies in five core research areas of magnetic resonance imaging and spectroscopy (MRI/MRS): # image reconstruction, fast imaging and radiofrequency (RF) pulse design methods, # R hardware development, # body imaging methods, # neuroimaging methods. # MR spectroscopy methods. In each of these areas, they capitalize on the long-standing, successful partnership and extensive experience in Stanford's Radiology and Electrical Engineering departments to improve and expand imaging technology for use in basic research and clinical care, and to provide cutting edge opportunities to the extramural community for biomedical research with MRI. Over its more than 18 years of existence, CAMRT has been motivated by and has served a wide base of extramurally sponsored collaborators and service users from leading medical and research institutions. Examples of collaborative projects are the development of real-time functional MRI biofeedback methods for neuroscience and clinical applications such as pain remediation, development of methods to mitigate metal artifacts in musculoskeletal imaging, development of novel RF pulses for many applications, and studies of breast cancer with efficient MRS methods.

Proper citation: Richard M. Lucas Center for Imaging (RRID:SCR_001406) Copy   

•   Source: SciCrunch Registry

http://www.bioinfor.com/zoom/general/overview.html

Software to map the Illumina/Solexa reads of 15x coverage of a human genome to the reference human genome in one CPU-day, allowing two mismatches, at full sensitivity.

Proper citation: ZOOM (RRID:SCR_002175) Copy   

•   Source: SciCrunch Registry

http://www.utsouthwestern.edu/education/medical-school/departments/airc/southwestern-nmr-center/index.html

Biomedical technology research center that develops and applies new methods for analysis of metabolic networks in intact tissues, animals and human patients. The importance of understanding abnormal metabolism in common diseases such as cancer, diabetes and heart disease has long been appreciated. Because of constraints in technology, however, much of this research has been conducted in isolated systems where clinical relevance may be uncertain. Progress in magnetic resonance technology provides a foundation for major advances towards new ways of imaging metabolism in patients. These new techniques offer the advantage of imaging biochemical pathways without radiation. The focus of this Resource is to bring these technologies to a level where clinical research is feasible through the development of new MR contrast agents, NMR spectroscopy at high fields, and imaging of hyperpolarized 13C.

Proper citation: Southwestern NMR Center for In Vivo Metabolism (RRID:SCR_001429) Copy   

•   Source: SciCrunch Registry

http://www.mri-resource.kennedykrieger.org/

Biomedical technology research center that provides expertise for the design of quantitative magnetic resonance imaging (MRI) and spectroscopy (MRS) data acquisition and processing technologies that facilitate the biomedical research of a large community of clinicians and neuroscientists in Maryland and throughout the USA. These methods allow noninvasive assessment of changes in brain anatomy as well as in tissue metabolite levels, physiology, and brain functioning while the brain is changing size during early development and during neurodegeneration, i.e. the changing brain throughout the life span. The Kirby Center has 3 Tesla and 7 Tesla state of the art scanners equipped with parallel imaging (8, 16, and 32-channel receive coils) and multi-transmit capabilities. CIS has an IBM supercomputer that is part of a national supercomputing infrastructure. Resources fall into the following categories: * MRI facilities, image acquisition, and processing * Computing facilities and image analysis * Novel statistical methods for functional brain imaging * Translating laboratory discoveries to patient treatment

Proper citation: National Resource for Quantitative Functional MRI (RRID:SCR_006716) Copy   

•   Source: SciCrunch Registry

http://www.velos.com

A commercial software developer.

Proper citation: Velos (RRID:SCR_008408) Copy   

•   Source: SciCrunch Registry

http://www.uzh.ch/keyinst/loreta

Software application which computes cortical three-dimensional distribution of current density of the brain based on the scalp-recorded electric potential distribution. The exact low resolution brain electromagnetic tomography method has the property of exact localization to test point sources, yielding images of current density with exact localization, albeit with low spatial resolution. eLORETA has no localization bias even in the presence of structured noise. Deep structures, such as the anterior cingulate cortex and mesial temporal lobes, can be correctly localized with these methods.

Proper citation: exact Low Resolution Electromagnetic Tomography (RRID:SCR_013830) Copy   

•   Source: SciCrunch Registry

http://www.megimaging.com/

A software program for source imaging Magnetoencephalographic data. Now MEG tools has added Imaged Coherence mapping, Talairach and MNI coordinates, Grainger Causality. MEG Tools also includes MR-FOCUSS, ECD, Beamformers and many other useful MEG tools. This is a Matlab-based software module that is used to image MEG data onto a patient's MRI. This software imports all MEG manufacture's data (4D-Neuroimaging/BTi, CTF and Neuromag/Elekta).

Proper citation: MEG Tools (RRID:SCR_000661) Copy   

•   Source: SciCrunch Registry

http://www.omicsexpress.com/sva.php

Software package to annotate, visualize, and analyze the genetic variants identified through next-generation sequencing studies, including whole-genome sequencing (WGS) and exome sequencing studies. SVA aims to provide the research community with a user-friendly and efficient tool to analyze large amount of genetic variants, and to facilitate the identification of the genetic causes of human diseases and related traits.

Proper citation: SVA (RRID:SCR_002155) Copy   

•   Source: SciCrunch Registry

https://www.synapse.org/ampad

Repository for distribution of various types of molecular data from human, cell-based and animal model biosamples, analytical results and research tools generated through multiple NIA-supported programs. Currently Portal supports AMP-AD Target Discovery and Preclinical Validation and MOVE-AD Consortia and translational center, MODEL-AD.

Proper citation: AMP-AD Knowledge Portal (RRID:SCR_016316) Copy   

•   Source: SciCrunch Registry

https://repository.niddk.nih.gov/study/119

Multi-center randomized clinical trial to determine if the addition of behavioral treatment to drug therapy for the treatment of urge incontinence will make it possible to discontinue the drug and still maintain a reduced number of accidents. The most popular treatments for urge incontinence are drug therapy and behavior therapy, each with its own limitations. In this clinical study, the Urinary Incontinence Treatment Network (UITN) aims to determine differences with the addition of behavioral treatment to drug therapy alone.

Proper citation: Behavior Enhances Drug Reduction of Incontinence (RRID:SCR_001495) Copy   

•   Source: SciCrunch Registry

http://hirisplex.erasmusmc.nl/

An interactive software tool that predicts hair and eye color based on genetics. The website includes both the IrisPlex system and the HIrisPlex system.

Proper citation: HIrisPlex system (RRID:SCR_014058) Copy   

•   Source: SciCrunch Registry

https://www.vicon.com/downloads/software/bodybuilder

Software package for modeling body biomechanics for use with the Vicon motion capture system. Bodybuilder allows users to, among other things, edit and modify trajectories and interpolate broken trajectories, model body segments and joints, create kinematic and kinetic models, and output results to text or file.

Proper citation: Bodybuilder (RRID:SCR_015002) Copy   

•   Source: SciCrunch Registry

http://www.rad.upenn.edu/sbia/

THIS RESOURCE IS NO LONGER IN SERVICE. Documented on June 2, 2023. Software package used to simulate brain images with local growth / atrophy within a prescribed spherical region. Specifically, given an input image and its segmented image, the location of the center of the spherical region, and the radius of that sphere, it simulates new images that have tissue growth or shrinkage within that pre-specified brain region according to given rates (atrophy for rates less than one and growth for rates greater than one). The algorithm uses an iterative procedure that tries to achieve the given level of volumetric change for brain tissues within the region, by seeking a smooth deformation field, whose Jacobian determinants match the prescribed volume change rate within the region. Note that in the current software, the simulation of growth or atrophy for brain tissue requires that the input spherical region has to cover some CSF or background regions.

Proper citation: Atrophy Simulation Package (RRID:SCR_006046) Copy   

•   Source: SciCrunch Registry