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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://www.ncbi.nlm.nih.gov/projects/gap/cgi-bin/study.cgi?study_id=phs000674.v1.p1
Human genetics data from an immense (78,000) and ethnically diverse population available for secondary analysis to qualified researchers through the database of Genotypes and Phenotypes (dbGaP). It offers the opportunity to identify potential genetic risks and influences on a broad range of health conditions, particularly those related to aging. The GERA cohort is part of the Research Program on Genes, Environment, and Health (RPGEH), which includes more than 430,000 adult members of the Kaiser Permanente Northern California system. Data from this larger cohort include electronic medical records, behavioral and demographic information from surveys, and saliva samples from 200,000 participants obtained with informed consent for genomic and other analyses. The RPGEH database was made possible largely through early support from the Robert Wood Johnson Foundation to accelerate such health research. The genetic information in the GERA cohort translates into more than 55 billion bits of genetic data. Using newly developed techniques, the researchers conducted genome-wide scans to rapidly identify single nucleotide polymorphisms (SNPs) in the genomes of the people in the GERA cohort. These data will form the basis of genome-wide association studies (GWAS) that can look at hundreds of thousands to millions of SNPs at the same time. The RPGEH then combined the genetic data with information derived from Kaiser Permanente''s comprehensive longitudinal electronic medical records, as well as extensive survey data on participants'' health habits and backgrounds, providing researchers with an unparalleled research resource. As information is added to the Kaiser-UCSF database, the dbGaP database will also be updated.
Proper citation: Resource for Genetic Epidemiology Research on Adult Health and Aging (RRID:SCR_010472) Copy
Provides services including sequencing library preparation and sequencing on Illumina MiSeq and NovaSeq 6000 platforms. Supports single cell sequencing on 10X Genomics Chromium Controller. Provides Illumina Infinium Beadchips, which includes variety of whole genome genotyping arrays as well as Infinium MethylationEPIC BeadChip.
Proper citation: University of California at San Diego Institute for Genomic Medicine Genomics Center Core Facilitiy (RRID:SCR_022740) Copy
Supports leading edge research with free access to advanced computing hardware and software.
Proper citation: University of Pittsburgh Center for Research Computing Core Facility (RRID:SCR_022735) Copy
https://github.com/goehringlab/saibr_fiji_plugin
Software application as platform independent protocol and FIJI plug-in to correct for autofluorescence using standard filter sets and illumination conditions. Spectral autofluorescence correction method based on simple 2- or 3-Channel images implemented in Python and Fiji. Used for performing spectral autofluorescence correction on biological images.
Proper citation: SAIBR (RRID:SCR_024804) Copy
https://github.com/KummerLab/SEQUIN
Analysis software for identification of synaptic loci from 3D image datasets.
Proper citation: SEQUIN:Synaptic Evaluation and QUantification by Imaging Nanostructure (RRID:SCR_026029) Copy
https://github.com/malonge/RagTag
Collection of software tools for scaffolding and improving modern genome assemblies. Reference-based scaffolder. Used for fast and flexible genome assembly scaffolding and improvement.
Proper citation: RagTag (RRID:SCR_027293) Copy
https://github.com/ReproNim/reproschema
Software standardized framework for creating, sharing, and reusing cognitive and clinical assessments. Standardized form generation and data collection schema to harmonize results by design across projects. Used for enhancing research reproducibility through standardized survey data collection.
Proper citation: ReproSchema (RRID:SCR_027848) Copy
https://cephalopod.team/histotomography/Octo9/
Resource serves as a 'Digital Specimen' for Digital Organismal Biology, providing interactive Neuroglancer-based visualization and 3D segmentation masks for major organ systems, including the digestive, respiratory, vascular, and nervous systems. It specifically annotates novel neural tracts including the Intermediate Longitudinal Tracts (iLT) and Arm-to-Arm U-Tracts (AAUT) as well as ~300 additional tissue and organ level segmentations. Provides high-resolution (0.7 µm isotropic), whole-organism microCT reconstruction of an intact hatchling Octopus bimaculoides.
Proper citation: Octopus bimaculoides Histotomography Blueprint (RRID:SCR_027759) Copy
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