Tools   Select Another Resource Report Type

http://www.cs.gsu.edu/~serghei/?q=drut

Software for Discovery and Reconstruction of Unannotated Transcripts in Partially Annotated Genomes from High-Throughput RNA-Seq Data.

Proper citation: DRUT (RRID:SCR_004351) Copy   

•   Source: SciCrunch Registry

http://www.sanger.ac.uk/resources/software/act/

A free tool for displaying pairwise comparisons between two or more DNA sequences. It can be used to identify and analyze regions of similarity and difference between genomes and to explore conservation of synteny, in the context of the entire sequences and their annotation. It is based on the software for Artemis, the genome viewer and annotation tool. ACT runs on UNIX, GNU/Linux, Macintosh and MS Windows systems. It can read complete EMBL and GENBANK entries or sequences in FASTA or raw format. Other sequence features can be in EMBL, GENBANK or GFF format.

Proper citation: ACT: Artemis Comparison Tool (RRID:SCR_004507) Copy   

•   Source: SciCrunch Registry

http://compbio.cs.wayne.edu/software/squeezambler/

Software to sequence and de novo assemble all distinct genomes present in a microbial sample with a sequencing cost and computational complexity proportional to the number of genome types, rather than the number of cells.

Proper citation: Squeezambler (RRID:SCR_004385) Copy   

•   Source: SciCrunch Registry

https://www.tgen.org/research/research-divisions/neurogenomics/supplementary-data/sniper-hd-improved-genotype-calling-accuracy.aspx#.UjmeKb5OKM8

Improved genotype calling accuracy by an expectation-maximization algorithm for high-density SNP arrays.

Proper citation: SNiPer-HD (RRID:SCR_004383) Copy   

•   Source: SciCrunch Registry

http://sourceforge.net/projects/vanator-cvr/

A Perl pipeline utilising a large variety of common alignment, assembly and analysis tools to assess the metagenomic profiles of Illumina deep sequencing samples. The emphasis is on the discovery of novel viruses in clinical and environmental samples.

Proper citation: Vanator (RRID:SCR_004370) Copy   

•   Source: SciCrunch Registry

http://www.csd.uwo.ca/~ilie/BOND/

Software program to compute highly specific DNA oligonucleotides, for all the genes that admit unique probes, while running orders of magnitude faster than the existing programs.

Proper citation: Basic OligoNucleotide Design (RRID:SCR_004492) Copy   

•   Source: SciCrunch Registry

http://cran.r-project.org/web/packages/RJaCGH/index.html

Software for Bayesian analysis of CGH microarrays fitting Hidden Markov Chain models.

Proper citation: RJaCGH (RRID:SCR_008381) Copy   

•   Source: SciCrunch Registry

http://www.cerc.utexas.edu/OnlineCall/

A fast basecalling scheme for Illumina''s Next Generation sequencing machines, specifically designed for GAII.

Proper citation: OnlineCall (RRID:SCR_008263) Copy   

•   Source: SciCrunch Registry

http://bioinfo.cipf.es/isacghtrac

Software to analyze CNV that will now normalize arrays CGH and it will visually integrate different genome annotations.

Proper citation: IsaCGH (RRID:SCR_008375) Copy   

•   Source: SciCrunch Registry

http://seqpig.sourceforge.net/

A software library for Apache Pig for the distributed analysis of large sequencing datasets on Hadoop clusters.

Proper citation: SeqPig (RRID:SCR_008548) Copy   

•   Source: SciCrunch Registry

http://mothra.ornl.gov/cgi-bin/cat/cat.cgi

A repository of tools for analysis and annotation of CAZYmes (Carbohydrate Active enZYmes).

Proper citation: CAT (RRID:SCR_008421) Copy   

•   Source: SciCrunch Registry

http://www.broadinstitute.org/scientific-community/science/programs/cancer/ultrasome

An efficient methodology for detecting and delineating gains and losses of chromosomal material in DNA copy-number data.

Proper citation: Ultrasome (RRID:SCR_008465) Copy   

•   Source: SciCrunch Registry

http://pga.mgh.harvard.edu/oligopicker/

Software to help selecting up to five oligo probes for each of the DNA sequences you provided for microarray spotting.

Proper citation: OligoPicker (RRID:SCR_008720) Copy   

•   Source: SciCrunch Registry

http://dc.crs4.it/projects/biodoop

A suite of parallel bioinformatics applications based upon a popular open-source Java implementation of MapReduce, Hadoop.

Proper citation: Biodoop (RRID:SCR_008711) Copy   

•   Source: SciCrunch Registry

http://code.google.com/p/drgap/

Designed to identify Driver Genes and Pathways in cancer genome sequencing studies.

Proper citation: DrGaP (RRID:SCR_008670) Copy   

•   Source: SciCrunch Registry

http://www.broadinstitute.org/cancer/cga/invex/

A permutation-based method (written in Python) for ascertaining genes with a somatic mutation distribution showing evidence of positive selection for non-silent mutations.

Proper citation: InVEx (RRID:SCR_008734) Copy   

•   Source: SciCrunch Registry

http://bioinformatics.wistar.upenn.edu/isoformex

Software that estimates transcript expression levels and gene expression levels from mRNA-Seq data. Technically speaking, IsoformEx parses bowtie alignment files in a project directory (e.g. ~yourid/isoformex/xxx, where xxx is the project name) and generates two files: (1) xxx/xxx_transcript_1.txt: expression levels of all transcripts, (2) xxx/xxx_gene_1.txt: expression levels of all genes.

Proper citation: IsoformEx (RRID:SCR_005235) Copy   

•   Source: SciCrunch Registry

http://code.google.com/p/aldex/

RNA-seq tool that uses the Dirichlet distribution and a transformation to identify genes that exhibit small within-condition and large between-condition variance.

Proper citation: aldex (RRID:SCR_005110) Copy   

•   Source: SciCrunch Registry

http://www.broadinstitute.org/cancer/cga/absolute

Software to estimate purity / ploidy, and from that compute absolute copy-number and mutation multiplicities. When DNA is extracted from an admixed population of cancer and normal cells, the information on absolute copy number per cancer cell is lost in the mixing. The purpose of ABSOLUTE is to re-extract these data from the mixed DNA population. This process begins by generation of segmented copy number data, which is input to the ABSOLUTE algorithm together with pre-computed models of recurrent cancer karyotypes and, optionally, allelic fraction values for somatic point mutations. The output of ABSOLUTE then provides re-extracted information on the absolute cellular copy number of local DNA segments and, for point mutations, the number of mutated alleles.

Proper citation: ABSOLUTE (RRID:SCR_005198) Copy   

•   Source: SciCrunch Registry

http://www.qcmg.org/bioinformatics/tiki-index.php

A single nucleotide variant caller optimised for identifying somatic variants in low cellularity cancer samples.

Proper citation: qSNP (RRID:SCR_005105) Copy   

•   Source: SciCrunch Registry