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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
Probalign
 
Resource Report
Resource Website
10+ mentions
Probalign (RRID:SCR_013332) Probalign software resource, image analysis software, alignment software, data processing software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software that uses partition function posterior probability estimates to compute maximum expected accuracy multiple sequence alignments. Computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities.Produces accurate alignments on long and heterogeneous length datasets containing protein repeats. is used by: eProbalign
is listed by: OMICtools
is listed by: Debian
has parent organization: New Jersey Institute of Technology; New Jersey; USA
PMID:16954142
DOI:10.1093/bioinformatics/btl472
THIS RESOURCE IS NO LONGER IN SERVICE OMICS_00985 https://sources.debian.org/src/probalign/ SCR_013332 Probalign: multiple sequence alignment using partition function posterior probabilities 2026-08-06 09:28:07 16
NGSmethDB
 
Resource Report
Resource Website
1+ mentions
NGSmethDB (RRID:SCR_012847) NGSmethDB storage service resource, service resource, data repository, data or information resource, database A dedicated database for the storage, browsing and data mining of whole-genome, single-base-pair resolution methylomes. bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:20965971 OMICS_01844, biotools:ngsmethdb https://bio.tools/ngsmethdb SCR_012847 NGSmethDB - A database for NGS single-cytosine-resolution DNA methylation data 2026-08-06 09:28:04 9
GenomeView
 
Resource Report
Resource Website
10+ mentions
GenomeView (RRID:SCR_012968) GenomeView database, data or information resource, software resource A next-generation stand-alone genome browser and editor initiated in the BSB group at VIB and currently developed at Broad Institute. is listed by: OMICtools PMID:22102585 OMICS_00913 SCR_012968 2026-08-06 09:28:02 36
TopHat
 
Resource Report
Resource Website
5000+ mentions
Rating or validation data
TopHat (RRID:SCR_013035) sequence analysis software, software resource, alignment software, image analysis software, data analysis software, data processing software, software application Software tool for fast and high throughput alignment of shotgun cDNA sequencing reads generated by transcriptomics technologies. Fast splice junction mapper for RNA-Seq reads. Aligns RNA-Seq reads to mammalian-sized genomes using ultra high-throughput short read aligner Bowtie, and then analyzes mapping results to identify splice junctions between exons.TopHat2 is accurate alignment of transcriptomes in presence of insertions, deletions and gene fusions. align, RNA-Seq, read, cDNA, sequencing, transcriptomics, fast, splice, junction, mapper, exon, analysis, bio.tools uses: Bowtie
is used by: CIRCexplorer
is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: HISAT2
has parent organization: University of Maryland; Maryland; USA
has parent organization: University of California at Berkeley; Berkeley; USA
has parent organization: Johns Hopkins University; Maryland; USA
has parent organization: University of Washington; Seattle; USA
works with: GeneScissors
NHGRI R01 HG006102;
NHGRI R01 HG006677
PMID:23618408
PMID:19289445
DOI:10.1093/bioinformatics/btp120
Free, Available for download, Freely available biotools:tophat, OMICS_01257 https://github.com/infphilo/tophat, https://bio.tools/tophat, https://sources.debian.org/src/tophat/ http://tophat.cbcb.umd.edu/ SCR_013035 tophat, TopHat1, Tophat2 2026-08-06 09:28:03 9575
MitoBreak
 
Resource Report
Resource Website
10+ mentions
MitoBreak (RRID:SCR_012949) MitoBreak storage service resource, service resource, data repository, data or information resource, database Database with curated datasets of mitochondrial DNA (mtDNA) rearrangements. Users may submit new mtDNA rearrangements. mitochondrial dna rearrangement, mitochondrial dna, deletion, duplication, linear, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
PMID:24170808 Free, The community can contribute to this resource biotools:mitobreak, OMICS_01640 https://bio.tools/mitobreak SCR_012949 2026-08-06 09:28:02 10
minfi
 
Resource Report
Resource Website
100+ mentions
minfi (RRID:SCR_012830) minfi software resource, data analysis software, data processing software, data visualization software, software application Software tools for analyzing and visualizing Illumina''s 450k array data. Illumina, array data, Analyze Illumina Infinium DNA methylation arrays, DNA methylation array, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: SWAN
has parent organization: Bioconductor
PMID:28035024 Free, Available for download, Freely available biotools:minfi, OMICS_00799, BioTools:minfi https://bio.tools/minfi, https://bio.tools/minfi, https://bio.tools/minfi SCR_012830 2026-08-06 09:28:04 390
affy
 
Resource Report
Resource Website
1000+ mentions
affy (RRID:SCR_012835) Affy data analysis software, software application, software resource, data processing software Software R package of functions and classes for the analysis of oligonucleotide arrays manufactured by Affymetrix. Used to process probe level data and for exploratory oligonucleotide array analysis. analysis, oligonucleotide, array, Affymetrix, process, probe, data, function, bio.tools is listed by: OMICtools
is listed by: Bioconductor
is listed by: Debian
is listed by: bio.tools
is listed by: SoftCite
is related to: affydata
is related to: R Project for Statistical Computing
is related to: OMICtools
Danish Biotechnology Instrument Center PMID:14960456 Free, Available for download, Freely available BioTools:affy, OMICS_00740, biotools:affy https://bio.tools/affy, https://sources.debian.org/src/r-bioc-affy/ SCR_012835 Affymetrix, analysis of Affymetrix GeneChip data at the probe level, analysis of Affymetrix GeneChip data 2026-08-06 09:28:04 2996
AcroMine
 
Resource Report
Resource Website
AcroMine (RRID:SCR_013196) service resource, data access protocol, web service, software resource An acronym dictionary which can be used to find distinct expanded forms of acronyms from MEDLINE. This freely available service can be used through your browser or by integrating it with your applications using the ReSTful service. Acromine identifies abbreviation definitions by assuming a word sequence co-occurring frequently with a parenthetical expression to be a potential expanded form. Applied to the whole MEDLINE (9,635,599 abstracts), the implemented system extracted 68,007 abbreviation candidates and recognized 467,402 expanded forms. The current Acromine achieves 99% precision and 82-95% recall on our evaluation corpus that roughly emulates the whole MEDLINE. acronym, abbreviation, disambiguation, computational linguistics, text mining is listed by: FORCE11
is listed by: OMICtools
has parent organization: University of Manchester; Manchester; United Kingdom
JISC ;
BBSRC ;
EPSRC
PMID:20360059
PMID:17050571
Free, Public OMICS_01169, nif-0000-10215 SCR_013196 Acromine 2026-08-06 09:28:05 0
Cufflinks
 
Resource Report
Resource Website
5000+ mentions
Cufflinks (RRID:SCR_014597) sequence analysis software, software resource, data analysis software, data processing software, software application Software tool for transcriptome assembly and differential expression analysis for RNA-Seq. Includes script called cuffmerge that can be used to merge together several Cufflinks assemblies. It also handles running Cuffcompare as well as automatically filtering a number of transfrags that are likely to be artifacts. If the researcher has a reference GTF file, the researcher can provide it to the script to more effectively merge novel isoforms and maximize overall assembly quality. transcriptome, rna-seq, rna seq, cuffmerge, cufflink, cuffcompare, transfrags, artifacts, gtf file, transcriptome assembly, expression analysis, bio.tools, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
is listed by: SoftCite
works with: GeneScissors
is hosted by: GitHub
DOI:10.1038/nbt.1621 Acknowledgement requested, Source code available on GitHub biotools:cufflinks, OMICS_01304, SCR_013307 https://github.com/cole-trapnell-lab/cufflinks, https://bio.tools/cufflinks, https://sources.debian.org/src/cufflinks/ SCR_014597 2026-08-06 09:28:23 8838
Prokka
 
Resource Report
Resource Website
1000+ mentions
Prokka (RRID:SCR_014732) sequence analysis software, software resource, data analysis software, data processing software, software application THIS RESOURCE IS NO LONGER IN SERVICE. Documented on February 28,2023. Software tool for the rapid annotation of prokaryotic genomes. It produces GFF3, GBK and SQN files that are ready for editing in Sequin and ultimately submitted to Genbank/DDJB/ENA. A typical 4 Mbp genome can be fully annotated in less than 10 minutes on a quad-core computer, and scales well to 32 core SMP systems., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. annotation, prokaryote, genome, prokaryotic genome, sequence analysis software, annotation software, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
DOI:10.1093/bioinformatics/btu153 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_04220, biotools:prokka https://bio.tools/prokka, https://sources.debian.org/src/prokka/, https://sources.debian.org/src/prokka/ SCR_014732 2026-08-06 09:28:27 4876
SeaView
 
Resource Report
Resource Website
1000+ mentions
SeaView (RRID:SCR_015059) sequence analysis software, software resource, data analysis software, data processing software, data visualization software, software application Graphical user interface for multiple sequence alignment and molecular phylogeny. SeaView also generates phylogenetic trees. sequence alignment, molecular phylogeny, phylogenetic tree, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
PMID:19854763
DOI:10.1093/molbev/msp259
Free, Available for download OMICS_08908, biotools:seaview https://bio.tools/seaview, https://sources.debian.org/src/seaview/ SCR_015059 2026-08-06 09:28:28 1777
Bustools
 
Resource Report
Resource Website
10+ mentions
Bustools (RRID:SCR_018210) data analysis software, software application, software resource, data processing software Software tool for manipulating BUS files for single cell RNA-Seq datasets. Used to error correct barcodes, collapse UMIs, produce gene count or transcript compatibility count matrices, and is useful for many other tasks. Single cell RNAseq workflow, single cell RNAseq dataset, error correct barcode, collapse UMI, produce gene count, produce transcript compatibility count matrice is listed by: Debian
is listed by: OMICtools
works with: kb_python
DOI:10.1101/673285 Free, Available for download, Freely available OMICS_33004 https://sources.debian.org/src/bustools/ SCR_018210 2026-08-06 09:29:18 18
Minimap2
 
Resource Report
Resource Website
1000+ mentions
Minimap2 (RRID:SCR_018550) software resource, image analysis software, alignment software, data processing software, software application Software tool as pairwise alignment for nucleotide sequences. Alignment program to map DNA or long mRNA sequences against large reference database. Versatile pairwise aligner for genomic and spliced nucleotide sequences. Pairwise alignment, nucleotide sequence, map DNA sequence, map mRNA sequence, reference database, spliced nucleotide sequence, bio.tools, FASEB list is used by: D-GENIES
is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
NHGRI R01 HG010040 PMID:29750242 Free, Available for download, Freely available OMICS_31658, biotools:minimap2 https://bio.tools/minimap2, https://sources.debian.org/src/libminimap2-dev/ SCR_018550 2026-08-06 09:29:20 1325
Phyutility
 
Resource Report
Resource Website
10+ mentions
Phyutility (RRID:SCR_018545) data analysis software, software application, software resource, data processing software Command line program that performs analyses or modifications on both trees and data matrices. Software phyloinformatics tool for trees, alignments and molecular data. Used for summarizing and manipulating phylogenetic trees, manipulating molecular data and retrieving data from NCBI. Data matrice analysis, data matrice modification, phyloinformatics, phylogenetic tree, alignment, molecular data manipulation, data analysis is listed by: Debian
is listed by: OMICtools
is listed by: SoftCite
is related to: NCBI
NSF Cyberinfrastructure for Phylogenetic Research EF 0331654 PMID:18227120 Free, Freely available OMICS_21687 https://sources.debian.org/src/phyutility/ SCR_018545 2026-08-06 09:29:27 42
SNPAAMapper
 
Resource Report
Resource Website
SNPAAMapper (RRID:SCR_002012) SNPAAMapper software application, data processing software, software resource THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2025. A downstream variant annotation program that can effectively classify variants by region (e.g. exon, intron, etc), predict amino acid change type (e.g. synonymous, non-synonymous mutation, etc), and prioritize mutation effects (e.g. CDS versus 5?UTR, etc). Major features: * The pipeline accepts the VCF (Variant Call Format) input file in tab-delimited format and processes the vcf input file containing all cases (G5, lowFreq, and novel) * The variant mapping step has the option of letting users select whether they want to report the bp distance between each identified intron variant and its nearby exon * The pipeline can deal with VCF files called by different SAMTools versions (0.1.18 and older ones) and also offers flexibility in dealing with vcf input files generated using SAMTools with two or three samples * The spreadsheet result file contains full protein sequences for both ref and alt alleles, which makes it easier for downstream protein structure/function analysis tools to take single nucleotide polymorphism, amino acid, variant, annotation, exon, intron, mutation, next-generation sequencing, perl, downstream analysis, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Michigan Medical School; Michigan; USA
PMID:24250114 THIS RESOURCE IS NO LONGER IN SERVICE OMICS_01922, biotools:snpaamapper https://bio.tools/snpaamapper SCR_002012 SNPAAMapper - A SNP Amino Acid Mapping tool 2026-08-06 09:25:35 0
Canadian College of Medical Geneticists
 
Resource Report
Resource Website
1+ mentions
Canadian College of Medical Geneticists (RRID:SCR_003013) CCMG portal, data or information resource, organization portal National voluntary specialty organization that serves its members, governments and public by Certifying individuals who provide medical genetics services, Establishing professional and ethical standards of medical genetics services, Establishing standards of medical genetics training, Providing professional and public education, Informing public policy. Canada, medical genetics, medical, genetics, medical genetics services is listed by: OMICtools THIS RESOURCE IS NO LONGER IN SERVICE OMICS_06305 SCR_003013 2026-08-06 09:25:46 2
HTqPCR
 
Resource Report
Resource Website
50+ mentions
HTqPCR (RRID:SCR_003375) HTqPCR software application, data processing software, software resource Software package for the analysis of Ct values from high throughput quantitative real-time PCR (qPCR) assays across multiple conditions or replicates. The input data can be from spatially-defined formats such ABI TaqMan Low Density Arrays or OpenArray; LightCycler from Roche Applied Science; the CFX plates from Bio-Rad Laboratories; conventional 96- or 384-well plates; or microfluidic devices such as the Dynamic Arrays from Fluidigm Corporation. HTqPCR handles data loading, quality assessment, normalization, visualization and parametric or non-parametric testing for statistical significance in Ct values between features (e.g. genes, microRNAs). data import, differential expression, gene expression, microtitre plate assay, multiple comparison, preprocessing, quality control, visualization, qpcr, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Bioconductor
has parent organization: European Bioinformatics Institute
PMID:19808880 Free, Available for download, Freely available biotools:htqpcr, OMICS_02314 https://bio.tools/htqpcr SCR_003375 HTqPCR - Automated analysis of high-throughput qPCR data 2026-08-06 09:25:52 74
NeuroMab
 
Resource Report
Resource Website
1000+ mentions
NeuroMab (RRID:SCR_003086) NeuroMab portal, data or information resource, organization portal A national mouse monoclonal antibody generating resource for biochemical and immunohistochemical applications in mammalian brain. NeuroMabs are generated from mice immunized with synthetic and recombinant immunogens corresponding to components of the neuronal proteome as predicted from genomic and other large-scale cloning efforts. Comprehensive biochemical and immunohistochemical analyses of human, primate and non-primate mammalian brain are incorporated into the initial NeuroMab screening procedure. This yields a subset of mouse mAbs that are optimized for use in brain (i.e. NeuroMabs): for immunocytochemical-based imaging studies of protein localization in adult, developing and pathological brain samples, for biochemical analyses of subunit composition and post-translational modifications of native brain proteins, and for proteomic analyses of native brain protein networks. The NeuroMab facility was initially funded with a five-year U24 cooperative grant from NINDS and NIMH. The initial goal of the facility for this funding period is to generate a library of novel NeuroMabs against neuronal proteins, initially focusing on membrane proteins (receptors/channels/transporters), synaptic proteins, other neuronal signaling molecules, and proteins with established links to disease states. The scope of the facility was expanded with supplements from the NIH Blueprint for Neuroscience Research to include neurodevelopmental targets, the NIH Roadmap for Medical Research to include epigenetics targets, and NIH Office of Rare Diseases Research to include rare disease targets. These NeuroMabs will then be produced on a large scale and made available to the neuroscience research community on an inexpensive basis as tissue culture supernatants or purified immunoglobulin by Antibodies Inc. The UC Davis/NIH NeuroMab Facility makes NeuroMabs available directly to end users and is unable to accommodate sales to distributors for third party distribution. Note, NeuroMab antibodies are now offered through antibodiesinc. antibody, brain, channel, disease-related protein, k channel subunit, mab, mammalian, membrane protein, monoclonal antibody, mouse, neuronal monoclonal antibody, neuronal protein, neuronal signaling molecule, reagent, receptor, research reagent, synaptic protein, transporter is used by: NIF Data Federation
is listed by: OMICtools
has parent organization: University of California at Davis; California; USA
NINDS ;
NIMH ;
NIH Blueprint for Neuroscience Research ;
NIH Roadmap for Medical Research ;
Office of Rare Diseases Research ;
Antibodies Inc.
Free, Freely available grid.482686.6, nif-0000-00175 https://ror.org/00fyrp007 SCR_003086 UCDavis/NIH NeuroMab Facility, antibodies.inc, antibodiesinc.com, antibodiesinc 2026-08-06 09:25:47 1810
MicroVigene
 
Resource Report
Resource Website
100+ mentions
MicroVigene (RRID:SCR_002820) image analysis software, software application, data processing software, software resource Automated software program for image analysis based on microarray based image application. Various output styles are available, including image overlay with warping and registration and scattered correlation plot with 2D or 3D spot profile. Outputs can be formatted in text, xml, excel, or custom format. image analysis, array image application, microarray image analysis is listed by: OMICtools Free, Freely available, Available for download OMICS_00845 SCR_002820 2026-08-06 09:25:44 102
NanoStringNorm
 
Resource Report
Resource Website
100+ mentions
NanoStringNorm (RRID:SCR_003382) NanoStringNorm software application, data processing software, software resource Software package for normalizing, diagnostics and visualization of NanoString nCounter data. Key features include an extensible environment for method comparison and new algorithm development, integrated gene and sample diagnostics, and facilitated downstream statistical analysis. normalization, nanostring ncounter, mirna, mrna, r, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Ontario Institute for Cancer Research
PMID:22513995 Free, Available for download, Freely available OMICS_02308, biotools:nanostringnorm https://www.rdocumentation.org/packages/NanoStringNorm/versions/1.2.1.1/topics/NanoStringNorm SCR_003382 NanoStringNorm: Normalize NanoString miRNA and mRNA data 2026-08-06 09:25:52 134

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