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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Cell Imaging Centre provides services and training for imaging and analysis of live or fixed cells and tissues.Image acquisition equipment and expert consultation for experimental design related to light and electron microscopy are offered, with full technical assistance, from sample processing through image analysis.
Proper citation: University of Alberta Faculty of Medicine and Dentistry Cell Imaging Centre Core Facility (RRID:SCR_019200) Copy
https://www.colorado.edu/lab/massspec/
Offers analytical and instructional expertise in mass spectrometry with practical training and access to instrumentation.Located in room C1B90 of Jennie Smoly Caruthers Biotechnology Building houses six mass spectrometry systems.Instruments are interfaced with chromatographic system in order to separate complex mixture samples. Offers training for open access to some instruments including Thermo ISO LT GCMS, Synapt G2 HDMS, Agilent 6120 LCMS, and 4000 Q-trap QQQ instruments.
Proper citation: Colorado University at Boulder Central Analytical Mass Spectrometry Core Facility (RRID:SCR_018992) Copy
https://brcf.medicine.umich.edu/cores/bioinformatics-core/
Core helps researchers identify and interpret patterns in RNA and DNA by placing sequencing data into biologically meaningful context. Services include experimental design, developing reproducible workflows, analyzing next-generation sequencing data, and supporting manuscript development/publication.
Proper citation: University of Michigan Medical School Bioinformatics Core (RRID:SCR_019168) Copy
https://directory.uchicago.edu/organizations/redirects?utf8=%E2%9C%93&orgs%5Bsub_departmentid%5D=934
Facility to manufacture cell based products and clinical grade reagents for treatment of patients on Phase I, II and III clinical trials. Cleanroom environment for manufacturing and preparing human cells, tissues and tissue based products. CAP Accredited.
Proper citation: University of Chicago Cellular and Tissue Based Processing cGMP Core Facility (RRID:SCR_019201) Copy
National and international arabidopsis germplasm resource.Stores over million genotypes in physical stocks servicing worldwide Arabidopsis community in more than 50 countries. Stocks are provided under identical cost recovery conditions to academic and commercial researchers. Non-transgenic stocks are sent gratis to K-17 institutions and in special cases. Provides seed and information resources to International Arabidopsis Genome Programme and research community. Maintains accessions of Arabidopsis thaliana (and small number of other related species), including Characterized lines, Mapping populations, and Insertion lines. You may browse or search catalog.
Proper citation: University of Nottingham NASC Nottingham Arabidopsis Stock Centre (RRID:SCR_019284) Copy
https://www.med.unc.edu/flowcytometry/
Core provides flow cytometry services to UNCCH research community as well as to others in Research Triangle Park area.Provides help with experimental design, sample acquisition, data analysis, and sorting, training to run analyzers independently at reduced cost, guidance about rigor and reproducibility in all aspects of experimental design, data acquisition, analysis and reporting.
Proper citation: University of North Carolina at Chapel Hill Flow Cytometry Core Facility (RRID:SCR_019170) Copy
https://transgenic.uchicago.edu
Provides investigators with genetically manipulated mice through transgenic technology or embryonic stem cell manipulation. Provides fully operational construction and gene targeting service. Offers annual course in Mouse Handling and Breeding. Provides transgenic plasmid and BAC, CRISPR and TARGATT injections, ES Cell targeting, screening, culture and blastocyst injections, rederivation, breeding and mouse services and consultation on project development.
Proper citation: University of Chicago Transgenic and ES Cell Technology Mouse Core Facility (RRID:SCR_019171) Copy
https://dentistry.musc.edu/research/gcohr
Core offers investigators opportunity to address research questions that require use of gnotobiotic animals. Standard services provide germ free mice (e.g. BALB/c, C57BL/6), deriving new strains of mice into germ free state by caesarean section, tissue collection and/or fluid from mice that have not received treatment or manipulations, exporting germ free mice in sterile transporters to other institutions. Non-Standard Services include maintaining and breeding newly derived germ free mice, administration of specialized diets, administration of compounds as therapeutic or disease-inducing agents, tissue collection and/or fluid from mice that have received treatment or manipulations.
Proper citation: Medical University of South Carolina College of Dental Medicine Gnotobiotic Animal Core Facility (RRID:SCR_018884) Copy
https://www.colorado.edu/chbe/instrument-shop
Provides mechanical and electrical design and fabrication services at CU Boulder.Provides solutions for instructional and research needs for any department or college. Collectively comprised of machine shop and electronics shop, both of which are located in basement level of Jennie Smoly Caruthers Biotechnology Building.
Proper citation: University of Colorado Boulder Chemical and Bio. Engineering instrument and electronics Core Facility (RRID:SCR_019298) Copy
https://med.nyu.edu/research/scientific-cores-shared-resources/applied-bioinformatics-laboratories
Core provides computational analysis for high throughput genomic data, including but not limited to, next generation sequencing data. Our mission is to accelerate scientific discoveries by guiding experimental design, performing robust data quality assessment, and carrying out comprehensive computational analyses. Registration to iLab required.
Proper citation: New York University Grossman School of Medicine Applied Bioinformatics Laboratories Facility (RRID:SCR_019178) Copy
https://www.boisestate.edu/brc/home/
Designed to provide supportive environment for interdisciplinary research and education with opportunities for students and faculty members alike with focus on biomolecules study with emphasis on proteins and protein interactions. Provides instrumentation and facilities for characterization of biomolecules and their role in variety of biomedical and environmental processes. Partnerships between Center and Idaho-BRIN/INBRE, UI, ISU, Boise VA Medical Center, College of Idaho, and Northwest Nazarene University. BRC provides seminars, training workshops, and other networking opportunities.
Proper citation: Boise State University Biomolecular Research Center Core Facility (RRID:SCR_019174) Copy
https://www.ualberta.ca/medicine/research/corefacilities/transgenic-facility/index.html
Core provides mouse transgenic and cryopreservation services including Sperm cryopreservation, Mouse in vitro fertilization, Mouse Rederivation, Transgenic Mouse Generation,DNA microinjection,CRISPR/Cas9-Mediated Genetically Engineered Mouse Production. Core equipment includes Hamilton Thorne Computer-Aided Sperm Analysis System,Sutter Xenoworks Micromanipulator,Sutter Xenoworks Digital Microinjector,Nikon TE2000 inverted microscope,MINC benchtop incubator,Leica M165 dissecting microscope.
Proper citation: University of Alberta Faculty of Medicine and Dentistry Transgenic Core Facility (RRID:SCR_019175) Copy
https://www.unh.edu/research/welcome-university-instrumentation-center
University wide core facility offers NMR,SEM including FIB, EBS, EBSD, Tensile Stage,Confocal,X-Ray Photoelectron Spectroscopy,X-Ray Microscope aka Micro CT, Expert analysis of research and industrial samples,Training in scientific instrument operation and data analysis, Maintenance, repair, and calibration of instruments,Specialty instrument engineering design and application services,Facilitation of access to scientific instruments throughout the university.
Proper citation: University of New Hampshire University Instrumentation Center Core Facility (RRID:SCR_021101) Copy
https://www.lsi.umich.edu/science/centers-technologies/center-structural-biology
Comprehensive structural biology resource.Provides high throughput protein laboratory for protein engineering, protein purification facilities for small- and large-scale protein production, macromolecular crystallization and crystallography laboratories for solving crystal structures of biological molecules, and X-ray facility with access to high energy synchrotron radiation. Provides expert guidance to researchers through every stage of project, collaborating and consulting with researchers who use the facilities. Service categories are Chemical, Material and Protein Characterization, Molecular Biology. Services include Cloning, Crystallization, Differential thermal analysis, Drug development, NMR (small molecule), PCR, Protein crystallography, Protein engineering, Protein production, Structure determination, Xray.
Proper citation: University of Michigan Center for Structural Biology Core Facility (RRID:SCR_021065) Copy
https://cami.northwestern.edu/
Provides access to range of preclinical imaging modalities and support services. These include MRI, nuclear imaging (PET, SPECT, and CT), in vivo bioluminescence and fluorescence imaging, animal housing and prep spaces, and tissue culture. Image analysis services are available, as are software packages (JIM, Amira, Matlab) and a workstation for users to perform their own data analysis. Imaging services can be provided for investigators' own animal models, or animal models can be supplied by the Developmental Therapeutics Core.
Proper citation: Northwestern University Center for Advanced Molecular Imaging Core Facility (RRID:SCR_021192) Copy
https://research.med.psu.edu/core-facilities/zebrafish/
Provides Penn State research community with modern, centralized facility for housing, breeding and performing experiments with zebrafish.Provides physical and intellectual infrastructure for investigators whose research can benefit from use of zebrafish as model system.
Proper citation: Penn State Hershey College of Medicine Zebrafish Functional Genomics Core Facility (RRID:SCR_021199) Copy
https://research.med.psu.edu/core-facilities/mri/
MRI and NMR magnetic resonance imaging facility for animal and human research, providing MRI methodologies and expertise for in vivo studies Laboratory space includes biochemical, electronic and surgical suites, and fully equipped machine shop with (2) 3D printers. MRI Core facility has two MRI systems and EEG MRI-compatible system.3T Siemens PRISMA-Fit scanner equipped with True 2 Channel Tx and 64 Channel Rx. The latest RF coil set including a 64 Channel head coil and software packages with full clinical capability.7T Biospec 70/20 as small animal imaging system (Bruker Biospin, Ettlingen, Germany). Latest Hardware and Software. Avance NEO with Paravision 360. Full sensory fMRI stimulation systems:SenSaVue System for visual and auditory stimulation (Invivo Corp, FL, USA), which includes an LCD visual display, audio system, button response unit and software (E-Prime) for paradigm creation, patient management, protocol planning, precise delivery of brain stimulation, and behavioral analysis.ETT Olfactometer with full-programmable 6 independent channels for odor and trigeminal stimulation (ETT, LLC, Hershey, PA).Olfact Smell Test System (Osmic Enterprises, Inc., Cincinnati, OH) is a computerized instrument to test the smell functions of human subjects. The smell functions that can be tested are odor threshold, odor identification, and odor memory.ETT Gustatometer with full-programmable 7 independent channels for taste stimulation (ETT,LLC, Hershey, PA) Eye Link 1000 Plus system via SR Research: The EyeLink 1000 Plus Host PC performs real-time eye tracking at 250, 500,1000, or 2000 samples per second while computing true gaze position on the display viewed by the participant. The Host PC also performs on-line detection and analysis of eye-motion events such as saccades, blinks, and fixations. In addition to the sample data, these events are stored in a data file on the Host PC. They can be sent through the Ethernet link to the Display PC with a minimal delay or output as analog signals (if the optional analog/digital I/O card is installed). From the Host PC, the operator performs participant setup, monitors their performance, and can communicate with applications running on a Display PC.
Proper citation: Penn State Hershey College of Medicine MRI Core Facility (RRID:SCR_021198) Copy
https://med.psu.edu/core/specimen-processing
Process, store and ship clinical trial samples from IRB approved studies. Collect remnant samples for outside company for instrument correlation, validation and specimen type verification with IRB approved protocol. CLIA Waver for urine pregnancy, urine dipstick results for participant study treatment.
Proper citation: Penn State Hershey College of Medicine Clinical Research Biospecimen Core Facility (RRID:SCR_021194) Copy
https://www.etsu.edu/com/mbcf/
Core provides Genomics, Transcriptomics and Proteomics Services to researchers.
Proper citation: East Tennessee State University Quillen College of Medicine Molecular Biology Core Facility (RRID:SCR_021106) Copy
https://www.coresri.org/facilities?facility_id=16
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on August 19,2022. Core offers contemporary imaging, molecular biology, histology, flow cytometry, cell sorting, and real-time gene expression. Provides technologies and training including specialized microscope facility.
Proper citation: Brown Alpert Medical School Women and Infants Hospital of Rhode Island Kilguss Research Institute Molecular Biology and Imaging Core Facility (RRID:SCR_021348) Copy
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