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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://www.cincinnatichildrens.org/research/cores/cardio-imaging
Offers imaging techniques using imaging and measurement tools. Offers consulting services ranging from educational seminars to assistance with grant and industry funding support.
Proper citation: Cincinnati Children's Hospital Cardiovascular Imaging Core Facility (RRID:SCR_022626) Copy
https://www.ohsu.edu/xd/research/research-cores/elemental-analysis/index.cfm
Provides highly sensitive elemental quantification, including sample preparation, data analysis, and experimental guidance, through Inductively Coupled Plasma Mass Spectrometry (ICP-MS) technology.
Proper citation: Oregon Health and Science University Elemental Analysis Core Facility (RRID:SCR_022746) Copy
Connects industry members with Penn State research community of artificial intelligence and machine learning researchers and their students to solve real world problems and seize market opportunities.
Proper citation: Penn State University Center for Applications of Artificial Intelligence and Machine Learning to Industry Core Facility (RRID:SCR_022867) Copy
https://www.ohsu.edu/knight-cardiovascular-institute/center-radiochemistry-research
Provides access to tools for imaging with short lived radionuclides, data analysis and is integrated with campus centers SARIC and nuclear medicine clinic for quantitative imaging of these tracers in vivo that provides spatial and temporal data in order to improve our basic understanding of biochemical pathways, disease processes and help select personalized treatments that enhance clinical care. Highlights of our center include On-campus capacity to develop and produce radiopharmaceuticals to address specific research questions using in-vivo, real-time imaging;PET/CT, SPECT/CT (and soon PET/MRI) imaging capability to quantify organ perfusion, assess metabolic pathways, receptor function and density, and measure pharmacodynamics.Applications are directed toward range of models, ranging from small animals to non-human primates, to humans.
Proper citation: Oregon Health and Science University Center for Radiochemistry Research Core Facility (RRID:SCR_022745) Copy
https://www.ohsu.edu/biophysics-core
Core services including ensurance that purified proteins and other biomolecules of interest are uncompromised in terms of their structure and stability. Facilitates analyses of catalytic activities and functional interactions.Examines thermodynamic and kinetic parameters for association between proteins and small molecules.Facilitates hypothesis generation through coalescence of experimental data and computational modeling.Assists in setting up protein crystallization assays.
Proper citation: Oregon Health and Science University Biophysics Core Facility (RRID:SCR_022744) Copy
https://www.cincinnatichildrens.org/research/divisions/b/bmi/resource-service
Provides computational resources, services, and support to investigators including clinical research informatics, application and technology development, and bioinformatics analyses.
Proper citation: Cincinnati Children's Hospital Biomedical Informatics Core Facility (RRID:SCR_022622) Copy
https://www.dental.upenn.edu/research/core-facilities/tissue-processing-laboratory/
Laboratory is located in Room 429 of the Levy Building.Services include tissue processing; H&E staining, trichrome, and other staining; creation of frozen sections; and deparaffinization. Provides cryostat for use by investigators within Penn Dental Medicine; cryostat training is available for a fee. Investigators requiring the services of the Tissue Processing Laboratory should contact the facility to arrange a meeting to set up the appropriate protocols. Special handling, specimen orientation, and any unique aspects of the tissue being processed will be discussed at that time; in some instances, it may be advantageous for the investigator to be present initially when the specimens are being oriented in the hot paraffin prior to the actual sectioning.
Proper citation: University of Pennsylvania School of Dental Medicine Tissue Processing Laboratory Core Facility (RRID:SCR_022863) Copy
https://www.med.unc.edu/genomics/about/
Full service sequencing facility to assist with genetic and genomic research. Part of Integrated Genomics Cores. Offers comprehensive library services, NextGen sequencing and alternative technologies including long reads. Offers library preparations and multiple sequencing platforms including MiSeq, HiSeq, NovaSeq, NextSeq, BioNano, Oxford Nanopore. Services also include using techniques and data analyses via sister core BARC.
Proper citation: UNC School of Medicine Integrated Genomics Cores High Throughput Sequencing Core Facility (RRID:SCR_022620) Copy
https://www.ohsu.edu/xd/research/research-cores/bdp.cfm
Core provides designing studies and developing statistical analysis plans in clinical trials, clinical and community based intervention studies, laboratory experiments, and observational studies.Provides expertise in traditional and modern statistical methods.Can help with trial design and analysis, epidemiologic analysis, sample size and power, high dimensional data analysis, risk prediction, complex survey analysis, time-to-event and longitudinal models, and statistical simulation,data management and wrangling, analytic variable coding and data set creation, research database design, data visualization, manuscript preparation, statistical programming, and much more.
Proper citation: Oregon Health and Science University Biostatistics and Design Program Core Facility (RRID:SCR_022741) Copy
https://advancedimaging.vetmed.ucdavis.edu/
Fluorescence microscopy facility with two Leica confocal microscopes, one with superresolution capability,second with multi-photon imaging capability, and Zeiss Lightsheet microscope. Facility offers consultation, training, and support.
Proper citation: University of California at Davis Veterinary Medicine Advanced Imaging Core Facility (RRID:SCR_022862) Copy
https://www.cincinnatichildrens.org/research/divisions/c/critical/medialab
Develops high quality video and animation to enhance medical education.
Proper citation: Cincinnati Children's Hospital Critical Care Media Lab Core Facility (RRID:SCR_022629) Copy
https://www.cincinnatichildrens.org/research/cores/translational-core-laboratory/viral-vector-core
Provides research grade retroviral, lentiviral and adeno associated virus vectors. Offers generation of stable producer lines, and non-GMP quality control testing including vector titer by functional assay FACS or PCR, endotoxin, mycoplasma, and USP sterility testing.Provides standard packaging plasmids, the investigator provides the viral vector to be used for the production run.
Proper citation: Cincinnati Children's Hospital Viral Vector Core Facility (RRID:SCR_022641) Copy
Provides facilities and expertise to support clinical assay development from technology developed in academic laboratories.Provides assay development and testing support for early phase clinical trials with focus on cell and gene therapy.
Proper citation: Cincinnati Children's Hospital Translational Trial Development and Support Laboratory Core Facility (RRID:SCR_022640) Copy
https://www.cincinnatichildrens.org/service/p/pathology/mass-spectrometry
Provides analytical resource focusing on application of mass spectrometry and allied chromatographies to analysis of small molecules, generally of less than 1,000 daltons molecular weight, in complex clinical and biological samples.
Proper citation: Cincinnati Children's Hospital Mass Spectrometry Core Facility (RRID:SCR_022638) Copy
https://research.wayne.edu/proteomics
Protein identification and proteome analysis using Orbitrao Eclipse,Fusion and Q Exactive LC-MS/MS platforms. Affinity selection for phosphopeptides with analysis using HCD, CID and ETD. Validation and quantitation of proteins using MRM with a TSQ Vantage triple quad.
Proper citation: Wayne State University Proteomics Core Facility (RRID:SCR_022879) Copy
https://www.cincinnatichildrens.org/service/c/clinical-trials/biobank
Provides access to services for standardized and centralized acquisition, processing, storage and distribution of biospecimens for research.
Proper citation: Cincinnati Children's Hospital Discover Together Biobank Core Facility (RRID:SCR_022632) Copy
https://www.cincinnatichildrens.org/research/cores/imaging
Provides access to advanced analytical imaging and image post-processing methods for collaborators involved in basic and clinical research.
Proper citation: Cincinnati Children's Hospital Imaging Research Center Core Facility (RRID:SCR_022631) Copy
https://www.med.uvm.edu/vigr/mpsf
Provides support for design, execution, and analysis of experiments involving Next Generation Sequencing through access and use of Illumina HiSeq 1500. Sequencer performs wide range of analysis including target preparation for RNAseq, Exome Seq, ChIP seq, Methyl Seq, whole genome sequencing, and small RNA sequencing.Core is involved in all aspects of Nanopore sequencing.
Proper citation: University of Vermont Larner College of Medicine Advanced Genome Technologies Massively Parallel Sequencing Core Facility (RRID:SCR_022696) Copy
https://www.janelia.org/support-team/flow-cytometry
Provides range of instrumentation and expertise for cell sorting and analysis that can support experimental needs related to single cells, cell line production, biosensor development, and dye analysis. Offers expertise in flow cytometry experimental design, operation of instruments, distribution of raw data and sort reports, interpretation of results, and preparation of graphics for presentation and publication.
Proper citation: Howard Hughes Medical Institute at Janelia Research Campus Flow Cytometry Shared Resource Core Facility (RRID:SCR_022690) Copy
https://www.fredhutch.org/en/research/shared-resources/core-facilities/therapeutic-products.html
Provides facilities and services in process development and manufacturing of Good Manufacturing Practice grade biologic and cellular therapeutic products for Phase 1/2 clinical trials. Supports the translation of ideas from academic laboratories to clinical trials.
Proper citation: Fred Hutchinson Cancer Center Therapeutic Products Core Facility (RRID:SCR_022725) Copy
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