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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.

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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
zAlign
 
Resource Report
Resource Website
zAlign (RRID:SCR_024360) aligment software Software tool as local sequence aligner intended for use with large biological DNA sequences, with more than 1 Millions of base pairs. sequence aligner, large biological DNA sequences, is listed by: Debian Free, Available for download, Freely available, OMICS_21299 https://sources.debian.org/src/zalign/ SCR_024360 zalign 2026-08-01 12:08:16 0
mzMatch
 
Resource Report
Resource Website
1+ mentions
mzMatch (RRID:SCR_000543) software toolkit, software resource A software to provide small tools for common processing tasks for LC/MS data. It is an extension to the metabolomics analysis pipeline mzMatch.R. The software is modular, open source, platform independent and written in Java. metabolomics, analysis, java, tool, peak extraction, filtering, normalization, derivative detection, identification, bio.tools is listed by: OMICtools
is listed by: bio.tools
is listed by: Debian
has parent organization: SourceForge
PMID:23162054 Free, Available for download, Freely available, biotools:mzmatch, OMICS_02642 https://bio.tools/mzmatch SCR_000543 2026-08-02 09:02:53 5
Bioinformatics Toolkit
 
Resource Report
Resource Website
100+ mentions
Bioinformatics Toolkit (RRID:SCR_010277) software toolkit, software resource A platform that integrates a great variety of tools for protein sequence analysis. Many tools are developed in-house, and serveral public tools are offered with extended functionality. Most frequently used tools HHpred Sensitive protein homology detection and structure prediction by HMM-HMM-comparison. Starting from a query sequence, HHpred builds a multiple sequence alignment using HHblits and turns it into a profile HMM. This is then compared it with a database of HMMs representing proteins with known structure (e.g. PDB, SCOP) or annotated protein families (e.g. PFAM, SMART, CDD, COGs, KOGs). The output is a list of closest homologs with alignments. HHpred can also build 3d homology models using the identified templates in the PDB database. It can optimize template picking and query-template alignments for homology modeling. The HHblits software is part of the open source package HHsuite. HHblits Remote homology detection method based on iterative HMM-HMM comparison. HHblits can build high-quality MSAs starting from single sequences or from MSAs. It transforms these into a query HMM and iteratively searches through uniprot20 or nr20 databases by adding significantly similar sequences from the previous search to the updated query HMM for the next search iteration. Compared to PSI-BLAST, HHblits is faster, up to twice as sensitive and produces more accurate alignments. The HHblits software is part of the open source package HHsuite. Quick2d Quick2D gives you an overview of secondary structure features like alpha-helices, extended beta-sheets, coiled coils, transmembrane helices and disorder regions. Predictions by PSIPRED, JNET, Prof(Rost), Prof(Ouali), Coils, MEMSAT2, HMMTOP, DISOPRED2 and VSL2. Modeller A Program for Comparative Protein Structure Modelling by Satisfaction of Spatial Restraints. Coils/PCoils This server compares a single sequence (COILS) or a sequence alignment (PCOILS) to a database of known coiled-coils and derives a similarity score. The program then calculates the probability that the sequence will adopt a coiled-coil conformation. PSI-Blast Search with an amino acid sequence against protein databases for locally similar sequences. Similar to ProteinBLAST but more sensitive. PSI-BLAST first performs a BLAST search and builds an alignment from the best local hits. This alignment is then used as a query for the next round of search. After each successive round the search alignment is updated. bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: OMICtools
DOI:10.1038/NMETH.1818 nlx_156936, OMICS_28407, biotools:bioinformatics_toolkit https://bio.tools/bioinformatics_toolkit, https://sources.debian.org/src/hhsuite/ SCR_010277 2026-08-02 09:05:41 235
VISTA Browser
 
Resource Report
Resource Website
50+ mentions
VISTA Browser (RRID:SCR_011808) software toolkit, software resource Software tools for comparative genomics.Comprehensive suite of programs and databases for comparative analysis of genomic sequences. There are two ways of using VISTA - you can submit your own sequences and alignments for analysis (VISTA servers) or examine pre-computed whole-genome alignments of different species. Comparative genomics tools, genomic sequences, comparative analysis, bio.tools, FASEB list is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: Lawrence Berkeley National Laboratory
Office of Biological and Environmental Research ;
Office of Science ;
US Department of Energy ;
NHLBI
PMID:15215394 Free, Freely available OMICS_00948, biotools:vista http://genome.lbl.gov/vista/index.shtml, https://bio.tools/vista SCR_011808 VISTA, vista 2026-08-02 09:06:03 87
HTQC
 
Resource Report
Resource Website
10+ mentions
HTQC (RRID:SCR_006448) HTQC software toolkit, software resource A software toolkit including statistics tool for illumina high-throughput sequencing data, and filtration tools for sequence quality, length, tail quality, etc.. c++, illumina, command-line is listed by: OMICtools
is listed by: Debian
has parent organization: SourceForge
PMID:23363224
DOI:10.1186/1471-2105-14-33
GNU General Public License, v3 OMICS_01052 https://sources.debian.org/src/htqc/ SCR_006448 HTQC - Quality control and filtration for illumina sequencing data 2026-08-02 09:04:55 42
Eagle
 
Resource Report
Resource Website
50+ mentions
Eagle (RRID:SCR_015991) software toolkit, software resource Software package for statistical estimation of haplotype phase either within a genotyped cohort or using a phased reference panel in large scale sequencing. The package includes Eagle1 (to harness identity-by-descent among distant relatives to rapidly call phase using a fast scoring approach) and Eagle2 (to analyze a full probabilistic model similar to the diploid Li-Stephens model used by previous HMM-based methods. hmm, hidden markov model, statistic, estimation, haplotype, phase, reference, panel, sequencing, algorithm, analysis, probability is listed by: Debian
is listed by: OMICtools
has parent organization: Broad Institute
NHGRI R01 HG006399;
NIMH R01 MH101244;
NHGRI F32HG007805;
Wellcome Trust WT098051;
Austrian Science Fund J-3401;
NHGRI HG007022;
NHLBI HL117626;
Fannie and John Hertz Foundation ;
NCRR S10 RR028832;
NWO 480-05-003;
Dutch Brain Foundation
PMID:27694958
PMID:27270109
Free, Available for download, Freely available OMICS_14099, SCR_017262 https://sources.debian.org/src/bio-eagle/, https://github.com/poruloh/Eagle, https://data.broadinstitute.org/alkesgroup/Eagle/downloads/ SCR_015991 Bio-eagle, Eagle1, Eagle2 2026-08-02 09:07:16 51
MultiQC
 
Resource Report
Resource Website
1000+ mentions
MultiQC (RRID:SCR_014982) data access protocol, software resource Data aggregate that compiles results from bioinformatics analyses across multiple samples into a single report. It is written in Python. bioinformatics, data aggregate, python, open source, html report, bio.tools is listed by: Debian
is listed by: bio.tools
is listed by: OMICtools
Science for Life Laboratory ;
National Genomics Infrastructure
PMID:27312411
DOI:10.1093/bioinformatics/btw354
Open source, Available for download biotools:multiqc, OMICS_12426 https://github.com/ewels/MultiQC https://pypi.python.org/pypi/multiqc, https://bio.tools/multiqc, https://sources.debian.org/src/multiqc/ SCR_014982 2026-08-02 09:07:05 3098
topGO
 
Resource Report
Resource Website
1000+ mentions
topGO (RRID:SCR_014798) software toolkit, software resource Software package which provides tools for testing GO terms while accounting for the topology of the GO graph. Different test statistics and different methods for eliminating local similarities and dependencies between GO terms can be implemented and applied. r, go, go graph, local similarities, software tool, software package, bio.tools is listed by: bio.tools
is listed by: Debian
is listed by: SoftCite
works with: Gene Ontology
is hosted by: Bioconductor
Available for download biotools:topgo https://bio.tools/topgo SCR_014798 2026-08-02 09:06:40 2839
DANPOS2
 
Resource Report
Resource Website
100+ mentions
DANPOS2 (RRID:SCR_015527) software toolkit, software resource Software toolkit with various functions for the analysis of nucleosome and protein occupancy by sequencing. nucleosome analysis, protein analysis, protein occupancy, bio.tools uses: Dpos
is listed by: bio.tools
is listed by: Debian
Available for download, Different versions are available for download biotools:danpos https://bio.tools/danpos SCR_015527 DANPOS 2026-08-02 09:06:57 111
HASTE-project
 
Resource Report
Resource Website
1+ mentions
HASTE-project (RRID:SCR_020932) software toolkit, software resource Software toolkit for rapid development of cloud native intelligent data pipelines for scientific data streams. Hierarchical approach to acquisition, analysis, and interpretation of image data. Developed in the project Hierarchical Analysis of Spatial and Temporal Data. Intelligent data pipelines development, intelligent spatial hierarchies, temporal information hierarchies, distributing data, data streams, image data hierarchical approach, image data, hierarchical analysis, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Freely available biotools:haste_toolkit https://bio.tools/haste_toolkit SCR_020932 HASTE Toolkit, Hierarchical Analysis of Spatial and TEmporal data, Hierarchical Analysis of Spatial and Temporal Data 2026-08-02 09:08:01 1
MERMAID
 
Resource Report
Resource Website
MERMAID (RRID:SCR_020939) software toolkit, software resource Registration toolbox written in pyTorch. Supports various image registration methods. Focuses on nonparametric registration approaches including stationary velocity fields and large discplacement diffeomorphic metric mapping models though simple affine registration is also possible. Allows for rapid prototyping of new image registration approaches and similarity measures. Image registration, nonparametric registration, rapid prototyping, new image registration, bio.tools is listed by: bio.tools
is listed by: Debian
is related to: Jupyter Notebook
Free, Available for download, Freely available biotools:MERMAID https://github.com/uncbiag/mermaid/blob/master/docs/source/index.rst, https://bio.tools/MERMAID SCR_020939 iMagE Registration via autoMAtIc Differentiation 2026-08-02 09:08:01 0
scVelo
 
Resource Report
Resource Website
100+ mentions
scVelo (RRID:SCR_018168) software toolkit, software resource Software package for estimating and analyzing RNA velocities in single cells using dynamical modeling. RNA Velocity using dynamical modeling. RNA veloscity, analysis, single cell, dynamic modeling, bio.tools is listed by: Debian
is listed by: bio.tools
Free, Available for download, Freely available biotools:scVelo https://scvelo.readthedocs.io/, https://bio.tools/scVelo SCR_018168 scvelo, single-cell RNA Velocity generalized to transient cell states 2026-08-02 09:07:46 199
GTDB-Tk
 
Resource Report
Resource Website
50+ mentions
GTDB-Tk (RRID:SCR_019136) software toolkit, software resource Open source software tool for assigning objective taxonomic classifications to bacterial and archaeal genomes based on Genome Database Taxonomy. Designed to work with recent advances that allow metagenome assembled genomes to be obtained directly from environmental samples. Can also be applied to isolate and single cell genomes. Assigning objective taxonomic classifications, bacterial genome, archaeal genome, Genome Database Taxonomy, metagenome assembled genome, environmental sample, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Available for download, Freely available biotools:GtDb-tk https://bio.tools/GTDB-Tk SCR_019136 GTDB-Tk v1.3.0, Genome Database Taxonomy-Tk 2026-08-02 09:07:57 79
ensembldb
 
Resource Report
Resource Website
10+ mentions
ensembldb (RRID:SCR_019103) software toolkit, software resource Software R package to create and use Ensembl based annotation resources. Ensembl based annotation, Ensembl, annotation, create annotation, use annotation, bio.tools is listed by: bio.tools
is listed by: Debian
PMID:30689724 Free, Available for download, Freely available biotools:ensembldb https://github.com/jorainer/ensembldb, https://bio.tools/ensembldb SCR_019103 ensembldb v2.6.8 2026-08-02 09:08:05 10
clustLasso
 
Resource Report
Resource Website
1+ mentions
clustLasso (RRID:SCR_018820) software toolkit, software resource Software R package to build predictive signatures of microbial phenotypes. Software package implementing cluster lasso approach. Predictive signatures, microbial phenotype, cluster lasso approach, build predictive signature, phenotype, data, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Freely available biotools:clustlasso https://bio.tools/clustlasso SCR_018820 2026-08-02 09:07:53 1
Spot
 
Resource Report
Resource Website
100+ mentions
Spot (RRID:SCR_018915) software toolkit, software resource Open source software tool for file based localization of numerical perturbations in data analysis pipelines. Identifies components in pipeline, at resolution level of system process, that produce different results in different execution conditions. Numerical perturbation, reproducibility, numerical differences, operating systems, neuroimaging pipeline stability, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Freely available, Available for download DOI:10.5281/zenodo.3873219, biotools:spottool https://bio.tools/spottool SCR_018915 Spot: File-based localization of numerical perturbations in data analysis pipelines 2026-08-02 09:07:54 141
Genomic Annotation in Livestock for positional candidate LOci
 
Resource Report
Resource Website
10+ mentions
Genomic Annotation in Livestock for positional candidate LOci (RRID:SCR_019212) GALLO software toolkit, software resource Software R package developed for accurate annotation of genes and quantitative trait loci located in regions identified in common genomic analyses performed in livestock, such as Genome Wide Association Studies and transcriptomics using RNA-Sequencing. Allows graphical visualization of gene and QTL annotation results, data comparison among different grouping factors like methods, breeds, tissues, statistical models, studies and QTL enrichment in different livestock species including cattle, pigs, sheep, and chickens. QTLs, multi-omics integration, qtl annotation, gene annotation, datamining, qtl enrichment analysis, livestock, bio.tools is listed by: CRAN
is listed by: bio.tools
is listed by: Debian
has parent organization: University of Guelph; Ontario; Canada
Free, Freely available biotools:genomic_annotation_in_livestock_for_positional_candidate_loci_gallo https://bio.tools/genomic_annotation_in_livestock_for_positional_candidate_loci_gallo SCR_019212 2026-08-02 09:08:06 14
SMI Services
 
Resource Report
Resource Website
1+ mentions
SMI Services (RRID:SCR_018881) SMI Services software toolkit, software resource Software suite of tools for cataloguing and anonymising DICOM files, as used for Scottish Medical Imaging project. Software suite of microservices for loading, anonymising, linking and extracting large volumnes of dicom medical images to support medical research. Platform allows dicom tags extracted from clinical images to be loaded into MongoDB and relational database tables for purposes of generating anonymous linked research extracts including image anonymisation. Database management system, anonymising DICOM files, cataloguing DICOM files, medical image, DICOM medical image, image anonymisation, bio.tools is listed by: bio.tools
is listed by: Debian
Free, Freely available biotools:smi_services https://bio.tools/smi_services SCR_018881 Scottish Medical Imaging Services 2026-08-02 09:07:53 1
psych
 
Resource Report
Resource Website
10+ mentions
psych (RRID:SCR_021744) software toolkit, software resource Software R package for multivariate analysis and scale construction using factor analysis, principal component analysis, cluster analysis and reliability analysis.Procedures for Psychological, Psychometric, and Personality Research. Used for personality, psychometric theory and experimental psychology. Psychological research procedure, Psychometric research procedure, Personality research procedure, factor analysis, principal component analysis, cluster analysis, reliability analysis is listed by: CRAN
is listed by: Debian
Free, Available for download, Freely available https://personality-project.org/r/psych/, https://sources.debian.org/src/r-cran-psych/ SCR_021744 2026-08-02 09:08:16 43
Mammalian Gene Collection
 
Resource Report
Resource Website
10+ mentions
Mammalian Gene Collection (RRID:SCR_007024) MGC cell repository, material resource, biomaterial supply resource NIH initiative project to provide full-length open reading frame (FL-ORF) clones for human, mouse, and rat genes, cow. MGC cDNA clones were obtained by screening of cDNA libraries, by transcript-specific RT-PCR cloning, and by DNA synthesis of cDNA inserts. All MGC sequences are deposited in GenBank and clones can be purchased from distributors of IMAGE consortium. With conclusion of MGC project in March 2009, GenBank records of MGC sequences will be frozen, without further updates. Since definition of what constitutes full-length coding region for some of genes and transcripts for which they have MGC clones will likely change in future, users planning to order MGC clones will need to monitor for these changes. Users can make use of genome browsers and gene-specific databases, such as the UCSC Genome browser, NCBI's Map Viewer, and Entrez Gene, to view relevant regions of genome (browsers) or gene-related information (Entrez Gene). cell line, cdna, frozen, clone, vector, gene, open reading frame, sequence, expressed sequence tag, bio.tools, FASEB list is listed by: One Mind Biospecimen Bank Listing
is listed by: bio.tools
is listed by: Debian
is related to: One Mind Biospecimen Bank Listing
is related to: NIDDK Information Network (dkNET)
is related to: ATCC
is related to: GenBank
is related to: Invitrogen Clones
is related to: Open Biosystems
is related to: Zebrafish Gene Collection
has parent organization: National Cancer Institute
NIH Blueprint for Neuroscience Research Free, Freely available biotools:mammalian_gene_collection, nif-0000-00195 https://bio.tools/mammalian_gene_collection SCR_007024 Mammalian Gene Collection 2026-08-04 09:41:44 46

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