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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Non-profit research center dedicated to the study of the human genome. Expert staff and pioneering programs in the fields of personalized medicine, cell biology, cytogenetics, genotyping, and biobanking drive our mission. The emerging field of personalized medicine draws upon a person's genomic information to tailor treatments and prescription drug dosing to optimize health outcomes. The Coriell Personalized Medicine Collaborative (CPMC) research study is seeking to understand the usefulness of genetic risk and pharmacogenomics in clinical decision-making and healthcare management. Coriell has a distinguished history in cell biology. We are building upon this expertise by playing an important role in induced pluripotent stem (iPS) cell research. These powerful cells, which can be made from skin cells or blood, are revolutionizing the way human disease is studied and how drugs are developed. The decline of neurons afflicted with Alzheimer's disease or pancreatic cells fighting diabetes can be studied in a Petri dish. By proving efficacy within the diseased environment prior to clinical trial, drugs can move through the pipeline quicker to reach patients sooner. In addition to pioneering cutting-edge research initiatives, Coriell offers custom research services including cell culture, cytogenetic analyses, and molecular biology to the scientific community. Furthermore, Coriell's Genotyping and Microarray Center is one of the nation's largest centers, with high-throughput DNA analysis systems from Illumina and Affymetrix. The Center is CLIA-certified in 48 states.
Proper citation: Coriell Institute for Medical Research (RRID:SCR_003043) Copy
Software platform designed to facilitate common management and productivity tasks for neuroimaging and associated data.
Proper citation: XNAT - The Extensible Neuroimaging Archive Toolkit (RRID:SCR_003048) Copy
https://biolincc.nhlbi.nih.gov/home/
Repository that serves to coordinate searches across data and biospecimen collections from participants in numerous clinical trials and epidemiologic studies and to provide an electronic means for requests for additional information and the submission of requests for collections. The collections, comprising data from more than 80 trials or studies and millions of biospecimens, are available to qualified investigators under specific terms and conditions consistent with the informed consents provided by the individual study participants. Some datasets are presented with studies and supporting materials to facilitate their use in reuse and teaching. Datasets support basic research, clinical studies, observational studies, and demonstrations. Researchers wishing to apply to submit biospecimen collections to the NHLBI Biorepository for sharing with qualified investigators may also use this website to initiate that process.
Proper citation: Biologic Specimen and Data Repository Information Coordinating Center (BioLINCC) (RRID:SCR_013142) Copy
Web application to discover resources available at participating networked universities. This distributed platform for creating and sharing semantically rich data is built around semantic web technologies and follows linked open data principles.
Proper citation: Eagle I (RRID:SCR_013153) Copy
http://www.chw.edu.au/research/groups/oncology/research_groups/paediatric/
Not yet vetted by NIF curator
Proper citation: Westmead Paediatric Tumour Bank (RRID:SCR_013087) Copy
Database that contains the complete entries of human ARE-containing full-length mRNAs.
ARED is further clustered into five groups depending on the number of motifs in the ARE stretch. Groups 1-4 contain five, four, three and two pentameric (AUUUA) repeats, respectively, while Group 5 contains only one repeat within the 13-bp pattern. Clustering was performed in such a way that, for example, Group 1 included not only exact five or more continuous ARE pentamers but also those with 10% ambiguity, so that a stretch of NUUUAUUUAUUUAUUUAUUUN would fall in this category. This process was verified by a phylogenic tree relationship using Clustal-W alignment of ARE stretches and their variations. As could be expected, this analysis showed that the lower the number of ARE motifs in a group, the higher the number of sequences that were included, and apparently the more functionally diverse the corresponding ARE-genes.
Proper citation: Adenylate Uridylate-rich-Rich Element-Containing mRNA Database (RRID:SCR_013107) Copy
http://www.csiro.au/resources/ASPREE-Biobank-Info-Sheet.html
Not yet vetted by NIF curator
Proper citation: ASPREE Healthy Ageing Biobank (RRID:SCR_013073) Copy
http://methycancer.psych.ac.cn/
Database to study interplay of DNA methylation, gene expression and cancer that hosts both highly integrated data of DNA methylation, cancer-related gene, mutation and cancer information from public resources, and the CpG Island (CGI) clones derived from our large-scale sequencing. Interconnections between different data types were analyzed and presented. Search tool and graphical MethyView are developed to help users access all the data and data connections and view DNA methylation in context of genomics and genetics data. The search tool and graphical MethyView are developed to help users access all the data and data connections and view DNA methylation in context of genomics and genetics data. As part of the Cancer Epigenomics Project in China, MethyCancer serves as a platform for sharing data and analytical results from the Cancer Genome/Epigenome Project in China with colleagues all over the world.
Proper citation: MethyCancer (RRID:SCR_013399) Copy
http://epsf.bmad.bii.a-star.edu.sg/cube/db/html/home.html
Cube-DB is a database of pre-evaluated conservation and specialization scores for residues in paralogous proteins belonging to multi-member families of human proteins. Protein family classification follows (largely) the classification suggested by HUGO Gene Nomenclature Committee. Sets of orhtologous protein sequences were generated by mutual-best-hit strategy using full vertebrate genomes available in Ensembl. The scores, described on documentation page, are assigned to each individual residue in a protein, and presented in the form of a table (html or downloadable xls formats) and mapped, when appropriate, onto the related structure (Jmol, Pymol, Chimera).
Proper citation: Cube-DB (RRID:SCR_013233) Copy
http://www.nitrc.org/projects/cmind_2014/
A database that contains brain imaging data collected on 3T MRI scanners from over 200 normally developing healthy children from birth to 18 years. The imaging data stored in the C-MIND database are DTI, HARDI, 3DT1W, 3DT2W, concurrent ASL-BOLD scans during two language tasks (Stories and Sentence-Picture Matching), Resting State fMRI and Baseline ASL scans.
Proper citation: C-MIND Database (RRID:SCR_014094) Copy
A standardized database for childrens disease classification and annotation. It is also an information exchange platform.
Proper citation: Pediatrics Annotation and Medicine (RRID:SCR_014417) Copy
Center for high-throughput DNA sequence generation and the accompanying analysis. The sequence data generated by the center's machines are analyzed in a complex bioinformatics pipeline, and the data are deposited regularly in the public databases at the National Center for Biotechnology Information (NCBI).
Proper citation: Baylor College of Medicine Human Genome Sequencing Center (RRID:SCR_013605) Copy
http://www.nitrc.org/projects/imeka_tracto
A diffusion MRI service that handles the processing of diffusion data from raw data to structural connectivity. They provide high angular resolution (HARDI) reconstruction from DTI data with at least 20 gradient directions acquisitions.
Proper citation: Imeka Tractography Service (RRID:SCR_014124) Copy
Ratings or validation data are available for this resource
A collaborative research project that supports nPOD approved diabetes investigators by freely providing rare and difficult-to-obtain tissues from type 1 and type 2 diabetes donors. Interested researchers are encouraged to apply to obtain nPOD tissues, or to request access to analyze cases in the nPOD Online Pathology site. Interested donors can contact nPOD directly for more information.
Proper citation: Network for Pancreatic Organ Donors with Diabetes (RRID:SCR_014641) Copy
http://www.socialstyrelsen.se/rarediseases
A database which contains detailed information rare diseases. The information is produced in collaboration with leading medical specialists and patient associations. New disease descriptions are added continuously and the texts are updated on a regular basis. Both the common names and the technical names for diseases are provided.
Proper citation: Swedish Information Centre for Rare Diseases (RRID:SCR_014571) Copy
http://web.stanford.edu/group/barres_lab/brain_rnaseq.html
Database containing RNA-Seq transcriptome and splicing data from glia, neurons, and vascular cells of cerebral cortex. Collection of RNA-Seq transcriptome and splicing data from glia, neurons, and vascular cells of mouse cerebral cortex. RNA-Seq of cell types isolated from mouse and human brain.
Proper citation: Brain RNA-Seq (RRID:SCR_013736) Copy
http://www.bloomberg.com/research/stocks/private/snapshot.asp?privcapId=30808
THIS RESOURCE IS NO LONGER IN SERVCE, documented September 2, 2016.
Proper citation: LifeCell Corporation (RRID:SCR_013593) Copy
http://www.med.umich.edu/mgpc/cores/vivo.htm
Core facility that consists of the following 4 distinct programs: In Vivo Small Animal Studies Program, Organoid/Enteroid Modeling Program, Biospecimens Banking Service, and Clinical Design and Statistics.
Proper citation: University of Michigan Center for Gastrointestinal Research In Vivo Animal and Human Studies Core (RRID:SCR_015608) Copy
http://www.nitrc.org/projects/ipa-spect_templ/
Template for p-[(123)I]iodo-L-phenylalanine( IPA)-SPECT in MNI-coordinates. This template was obtained from 12 human subjects in an NITRC study.
Proper citation: p-[(123)I]iodo-L-phenylalanine (IPA)-SPECT template in MNI-coordinates (RRID:SCR_015848) Copy
http://www.uchicagoddrcc.org/research-cores/tissue-and-cell-analysis-core
Core whose services include anatomic pathology review of human and experimental animal tissues as well as consultation in the best approaches for such analyses, cost-effective and high quality processing and staining of formalin-fixed paraffin-embedded tissues, and making collections of human tissue and imaging technologies available to researchers.
Proper citation: University of Chicago Digestive Diseases Research Core Center Tissue and Cell Imaging Core (RRID:SCR_015607) Copy
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