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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
A collection of web tools designed to assist with the analysis of DNA microarray data and results. RACE performs probe level data preprocessing, quality checks, normalization, and visualization for Affymetrix GeneChips. In addition, it performs clustering and differential analysis of normalized expression levels or ratios for arbitrary platforms, and estimates the false discovery rates in lists of potentially regulated genes. A Gene Ontology (GO)-term analysis assists in the biological interpretation of gene lists. The user can customize each analysis request; upon submission the analysis is executed in a fully automated way., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: RACE (RRID:SCR_010950) Copy
http://www.imtech.res.in/raghava/hslpred/
A support vector machine (SVM)-based method for the prediction of 4 major subcellular localization (cytoplasm, mitochondrial, nuclear and plasma membrane) of human proteins using various features such as i) amino acid composition, ii) dipeptide composition and iii) evolutionary information of proteins.
Proper citation: HSLPred (RRID:SCR_011972) Copy
http://159.149.160.51/pscan_chip_dev/
Web server that, starting from a collection of genomic regions derived from a ChIP-Seq experiment, scans them using motif descriptors like JASPAR or TRANSFAC position-specific frequency matrices, or descriptors uploaded by users, and it evaluates both motif enrichment and positional bias within the regions according to different measures and criteria.
Proper citation: Pscan-ChIP (RRID:SCR_010885) Copy
http://genes.mit.edu/GENSCAN.html
Web server for identification of complete gene structures in genomic DNA.Tool for predicting locations and exon-intron structures of genes in genomic sequences from variety of organisms. Used for prediction of complete gene structures in human genomic DNA.
Proper citation: GENSCAN (RRID:SCR_013362) Copy
http://probalign.njit.edu/probalign/login
Data analysis service that computes maximal expected accuracy multiple sequence alignments from partition function posterior probabilities.
Proper citation: eProbalign (RRID:SCR_013247) Copy
A tool to predict changes in protein stability upon point mutations.
Proper citation: CUPSAT (RRID:SCR_010773) Copy
http://ls-snp.icm.jhu.edu/ls-snp-pdb/
A web tool for genome-wide annotation of human SNPs.
Proper citation: LS-SNP/PDB (RRID:SCR_010774) Copy
http://plantgrn.noble.org/PlantTFcat/
A web-based analysis tool that is designed to identify and categorize plant TF/TR/CR genes from genome-scale protein and nucleic acid sequences by systematically analyzing InterProScan domain patterns in protein sequences., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: PlantTFcat (RRID:SCR_010898) Copy
http://koch.pathogenomics.ca/cgi-bin/pub/arraypipe.pl
A flexible tool for visualizing and analyzing your two-colour microarray slides.
Proper citation: ArrayPipe (RRID:SCR_010934) Copy
http://model.nmr.ru/preddimer/
Prediction tool to reconstruct putative dimer conformations for given sequences of transmembrane protein fragments, which are considered as ideal alpha-helices.
Proper citation: PREDDIMER (RRID:SCR_011963) Copy
http://smithlabresearch.org/software/methbase/
Central reference methylome database created from public BS-seq datasets. Provides methylation level at individual sites, regions of allele specific methylation, hypo- or hyper-methylated regions, partially methylated regions, and detailed meta data and summary statistics.
Proper citation: MethBase (RRID:SCR_017487) Copy
http://snpeff.sourceforge.net/SnpSift.html
Software toolkit for filtering and manipulating annotated files. After annotation, the software's filter function can find relevant genomic variants in large data files.
Proper citation: SnpSift (RRID:SCR_015624) Copy
https://github.com/stamatak/ExaML
Source code for large-scale phylogenetic analyses on whole-transcriptome and whole-genome alignments using supercomputers.
Proper citation: Examl (RRID:SCR_016087) Copy
http://sourceforge.net/projects/phenofam/
A web-based application that performs gene set enrichment analysis (GSEA) by employing structural and functional information on families of protein domains as annotation terms.
Proper citation: PhenoFam (RRID:SCR_000640) Copy
https://github.com/citiususc/veryfasttree
Software tool for speeding up estimation of phylogenetic trees for large alignments through parallelization and vectorization strategies.
Proper citation: VeryFastTree (RRID:SCR_023594) Copy
http://www.bioconductor.org/packages/release/bioc/html/ReadqPCR.html
A software package that provides functions to read raw RT-qPCR data of different platforms.
Proper citation: ReadqPCR (RRID:SCR_000030) Copy
http://mzmatch.sourceforge.net/
A software to provide small tools for common processing tasks for LC/MS data. It is an extension to the metabolomics analysis pipeline mzMatch.R. The software is modular, open source, platform independent and written in Java.
Proper citation: mzMatch (RRID:SCR_000543) Copy
http://faculty.washington.edu/browning/floss/floss.htm
Software application that performs ordered subset analysis using MERLIN's ouput .lod file created with the --perFamily option. Ordered subset analysis uses covariate information to identify a more homogenous subset of families for linkage analysis. The homogeneous subset of families does not need to be specified a priori, and the covariates can include environmental exposures, quantitative traits, or linkage scores at another locus in the genome. The evidence for linkage is evaluated with a permutation test. (entry from Genetic Analysis Software)
Proper citation: FLOSS (RRID:SCR_000836) Copy
http://www.sanger.ac.uk/science/tools/dindel
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 7,2024. Software program for calling small indels from short-read sequence data ("next generation sequence data"). It is currently designed to handle only Illumina data. Dindel takes BAM files with mapped Illumina read data and enables researchers to detect small indels and produce a VCF file of all the variant calls. It has been written in C++ and can be used on Linux-based and Mac computers (it has not been tested on Windows operating systems).
Proper citation: DINDEL (RRID:SCR_001827) Copy
http://sourceforge.net/projects/metabnorm/
Software tool as mixed model normalization method for metabolomics data.Uses normalization approach based on mixed model, with simultaneous estimation of correlation matrix.
Proper citation: metabnorm (RRID:SCR_001266) Copy
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