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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
Cell imaging system for fast, automated imaging in fixed and live cells. Instrument can rapidly image cells using laser autofocusing, LED light source and CMOS camera.
Proper citation: GE: Healthcare: IN Cell Analyzer 2200 (RRID:SCR_023616) Copy
https://www.ionpath.com/mibiscope/
Imaging platform, enabling phenotypic profiling and spatial analysis of tissue microenvironment. Enables over 40 markers to be visualized simultaneously with single step staining and single step imaging.
Proper citation: Ionpath: MIBIscope System (RRID:SCR_023613) Copy
https://www.htximaging.com/htx-m5-sprayer
Sprayer builds on capabilities of HTX TM-Sprayer providing innovative M5 chassis, high velocity stage and heated sample holder drawer. Sample plate holder is mounted on drawer mechanism to allow easy loading of samples, better protection of user and better alignment of various plate types. New High-Velocity XY stage allows nozzle displacement speed of up to 5,600mm/min and expands process range. Super dry spray can be achieved at high flow rates of solvent further improving instrument performance. E/Z trough gutter design improves chemical containement and is easy to remove and clean. Bulkhead connectors are directly mounted on it to also allow easy access to in line filter.
Proper citation: HTXImaging: M5 Sprayer (RRID:SCR_023733) Copy
https://www.htximaging.com/tm-sprayer
Allows users to adjust both gas flow rate and nozzle velocity to control drying time, preventing analyte delocalization and formation of large matrix crystals, known to create hot spots on MALDI images. Allows to heat matrix solution as it is being applied to their sample. By increasing temperature of matrix solution, absorption of matrix into sample is increased, resulting in greater MALDI image resolution.
Proper citation: HTXImaging: TM-Sprayer (RRID:SCR_023732) Copy
https://www.htximaging.com/htx-m3-sprayer
Sample preparation platform offering automated advanced MALDI matrix sprayer.
Proper citation: HTXImaging: M3+ Sprayer (RRID:SCR_023731) Copy
Mass spectrometer designed for most difficult analytical challenges. Incorporates inventions in ion transmission and control, extended m/z range, and real-time decision making. System suited for proteomics, structural biology, small-molecule, and biopharmaceutical characterization experiments.
Proper citation: Thermo Fisher: Orbitrap Eclipse Tribrid mass spectrometer (RRID:SCR_023618) Copy
Inverted microscope Axio Observer 3 for transmitted light brightfield LED and differential interference contrast. Used for demanding multimodal imaging.
Proper citation: Zeiss: Axio Observer 3 (RRID:SCR_023693) Copy
https://www.akoyabio.com/phenocycler/instrument/
PhenoCycler-Fusion system is integrated platform combining automated, ultrahigh-plex cycling platform, Akoya PhenoCycler, and its high-speed imaging platform, PhenoImager (formerly Phenoptics), into end-to-end, integrated workflow.
Proper citation: Akoya Biosciences: PhenoCycler-Fusion (RRID:SCR_023773) Copy
https://www.nikon.com/company/news/2018/0319_nsim_s_01.html
Microscope enables super solution imaging of live cells at ten times the speed of conventional SIM. Powered by ECLIPSE Ti2-E Inverted Research Microscope, taking advantage of its advanced optics, stability and features.
Proper citation: Nikon: N-SIM S Super Resolution Microscope (RRID:SCR_023803) Copy
https://www.leica-microsystems.com/products/thunder-imaging-systems/p/thunder-imager-3d-live-cell/
Advanced widefield microscope enabling use of 3D specimens with camera based fluorescence microscopes. System ensures low phototoxicity and photobleaching, i.e., higher throughput with optimal conditions.
Proper citation: Leica: Thunder Imager Live Cell system (RRID:SCR_023794) Copy
https://www.ttuhsc.edu/pharmacy/research/documents/Amnis-Imagestream-Manual.pdf
Bench top multispectral imaging flow cytometer designed for the acquisition of up to 12 channels of cellular imagery. It combines per cell information with statistical significance of sample sizes of standard flow cytometry.
Proper citation: Luminex: Amnis ImageStreamX Mk II System (RRID:SCR_018589) Copy
https://timothyspringer.org/files/tas/files/biacore3000-instrument.pdf
Biacore 3000 processing unit is an established, label-free system for detailed studies of biomolecular interactions. The system delivers comprehensive characterization of the interaction, answers questions about the rate constants, affinity, specificity, and determines the active concentration of components. The ability to recover and transfer interaction partners directly to MALDI targets for identification and further characterization makes the system highly applicable to fast identification of unknown interactants.
Proper citation: GE: Biacore 3000 Real Time Biomolecular Interaction Analyzer (RRID:SCR_018044) Copy
Benchtop genetic analyzer. Electrophoresis system for DNA and RNA sample quality control. It can be used for next generation sequencing or Biobank workflow.
Proper citation: Agilent: 4200 TapeStation System (RRID:SCR_018435) Copy
https://www.agilent.com/cs/library/brochures/5990-5596EN.pdf
Agilent 3100 OFFGEL Fractionator performs isoelectric focusing of proteins or peptides in immobilized pH gradient (IPG) gel strips.
Proper citation: Agilent: 3100 OFFGEL Fractionator (RRID:SCR_018433) Copy
http://tools.thermofisher.com/content/sfs/manuals/cms_040970.pdf
Automated PCR instrument for automated amplification of nucleic acids with Polymerase Chain Reaction. It has reaction volumes of up to 50 uL and sample temperature range of 4 to 99.9 C.
Proper citation: Thermo Fisher: Applied Biosystems: GeneAmp 9700 PCR Thermocycler System (RRID:SCR_018436) Copy
Center coordinates ideas and investments to advance and democratize access to Stanford cores, instrumentation, scientific and technical staff, allowing users to perform innovative, rigorous experiments.
Proper citation: Stanford University Community of Shared Advanced Research Platforms (RRID:SCR_022986) Copy
https://www.rankinbiomed.com/product/refurbished-american-optical-860-sliding-micrtome/
THIS REOURCE IS NO LONGER IN SERVICE. Documented on September 29,2023. Sliding microtome used for cutting hard objects such as bone, wood, frozen celloidin, and paraffin preparations. Cutting thickness is adjustable from 1 to 40 microns.
Proper citation: American Optical: 860 Sliding Microtome (RRID:SCR_018434) Copy
https://atagousa.corecommerce.com/PAL-10S-p358.html
Digital hand held pocket refractometer that measures urine specific gravity. It has measurement temperature of 10 to 35 C and sample volume of 0.3ml.
Proper citation: Atago: PAL-10S Pocket Refractometer (RRID:SCR_018439) Copy
https://www.sutter.com/manuals/P-2000_OpMan.pdf
Microprocessor controlled, CO2 laser based micropipette puller.Default configuration allows fabrication of micropipettes for intracellular recording, patch clamping, microinjection and microperfusion.Can store up to 100 separate programs, each consisting of up to 8 command lines. The five parameters set in each command line allow exquisite control of the micropipette taper geometry. Allows the use of wide range of glass diameters from 0.125 to 1.2 mm.
Proper citation: Sutter: P-2000 Laser Micropipette Puller (RRID:SCR_018640) Copy
https://www.ohsu.edu/transgenic-mouse-models-core
Core assists investigators with developing genetically engineered rodent models of human diseases for studying mutant genes and investigating molecular mechanisms underlying pathological processes.
Proper citation: OHSU Animal Model Support Core Facility (RRID:SCR_009994) Copy
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