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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
http://nectarmutation.org/main
A database and web application to annotate disease-related and functionally important amino acids in human proteins., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: NECTAR (RRID:SCR_007757) Copy
Database containing several body fluid proteomes, including plasma, urine, and cerebrospinal fluid. Cell lines have been mapped to a depth of several thousand proteins and the red blood cell proteome has also been analyzed in depth. The liver proteome is represented with 3200 proteins. By employing high resolution MS and stringent validation criteria, false positive identification rates in MAPU are lower than 1:1000. Thus MAPU datasets can serve as reference proteomes in biomarker discovery. MAPU contains the peptides identifying each protein, measured masses, scores and intensities using a clickable interface of cell or body parts. Proteome data can be queried across proteomes by protein name, accession number, sequence similarity, peptide sequence and annotation information. More than 4500 mouse and 2500 human proteins have already been identified in at least one proteome. Basic annotation information and links to other public databases are provided in MAPU and we plan to add further analysis tools.
Proper citation: Max Planck Unified Proteome Database (RRID:SCR_007771) Copy
http://bioportal.kobic.re.kr/SNPatETHNIC/
SNP at Ethnos is a catalog of human SNPs and genes that contain human ethnic variation. The database contains the following results for detecting natural selection and population difference: * Neareast Shrunken Centroid Method Score for detecting ethnic difference * Fst * Hudson, Kreitman and Aguade (HKA) test (1987) * Tajima''''s D test (1989) * Fu and Li D test (1993) It also contains copious links to dbSNP, Entrez Gene, GeneCards, OMIM, HGMD, International HapMap SNP at domain, and Haplotter (EHH). You can search by entering a gene symbol or an rs number in the text box at Data Search page. Search results provide above selection analysis data, rs lists corresponding a searched gene, and a genome viewer which contains functional annotation. The data underlying these analyses are from the Phase I HapMap Project.
Proper citation: SNP at Ethnos (RRID:SCR_007940) Copy
Data analysis service that allows to process CEL files from Affymetrix, Inc. GeneChip Gene 1.0 ST Arrays to identify alternative splicing.
Proper citation: Gene Array Analyzer (RRID:SCR_008323) Copy
http://nred.matticklab.com/cgi-bin/ncrnadb.pl
Database of long noncoding RNA expression that integrates annotated expression data from various sources in human and mouse. The database contains both microarray and in situ hybridization data, and supplies a rich tapestry of ancillary information for featured ncRNAs, including evolutionary conservation, secondary structure evidence, genomic context links and antisense relationships.
Proper citation: ncRNA Expression Database (RRID:SCR_008630) Copy
http://centerforaging.duke.edu/index.php?option=com_content&view=article&id=115&Itemid=152
The project has been collecting detailed panel data about the health, disability, demographic, family, socioeconomic, and behavioral risk-factors for mortality and healthy longevity of the oldest old, with a comparative sub-sample of younger elders, to examine the factors in healthy longevity. The baseline survey was conducted in 1998 and the follow-up surveys with replacement to compensate for deceased elders were conducted in 2000, 2002, 2005, and 2008, For each centenarian, one near-by octogenarian (aged 80-89) and one near-by nonagenarian (aged 90-99) of pre-designated age and sex were interviewed. Near-by is loosely defined it could be in the same village or street if available, or in the same town or in the same county or city. The idea was to have comparable numbers of male and female octogenarians and nonagenarians at each age from 80 to 99. In 2002, the study added a refresher sub-sample of 4,845 interviewees aged 65-79, and a sub-sample of 4,478 adult children (aged 35-65) of the elderly interviewees aged 65-110 in eight provinces Comparative study of intergenerational relationships in the context of rapid aging and healthy longevity between Mainland China and Taiwan is possible. At each wave, the longitudinal survivors were re-interviewed, and the deceased interviewees were replaced by additional participants. Data on mortality and health status before dying for the 12,136 elders aged 65-112 who died between the waves were collected in interviews with a close family member of the deceased. The study also included interviews and follow-ups with 4,478 elderly interviewees'''' children aged 35-65. * Dates of Study: 1998-2005 * Study Features: Longitudinal, International * Sample Size: ** 1998: 8,993 ** 2000: 11,199 ** 2002: 16,064 ** 2005: 14,923 Links * Data Archive, http://www.geri.duke.edu/china_study/CLHLS6.htm * ICPSR, http://www.icpsr.umich.edu/icpsrweb/NACDA/studies/03891
Proper citation: Chinese Longitudinal Healthy Longevity Survey (CLHLS) (RRID:SCR_008904) Copy
http://clinicalinformatics.stanford.edu/services/biobank.html
THIS RESOURCE IS NO LONGER IN SERVICE. Documented on March 7th, 2023. An online, searchable record of biospecimen attributes and storage location for the following three biobanks at Stanford: * The Bone Marrow Transplant (BMT) program * The Hematology biospecimen bank is a research sample repository focusing on blood, plasma and bone marrow, primarily from leukemia patients. * Cancer Center Pathology Core: The Stanford Comprehensive Cancer Center Tissue Bank stores research samples of both solid tumor and blood from cancer patients, with an emphasis on prostate. As of November 2009, the system contains data on 50,000 biospecimens stored in multiple banks at Stanford. An anonymous Biospecimen Locator allows Stanford researchers to search the STRIDE Virtual Biospecimen Bank for suitable samples without having to know, or expose, any protected patient-specific information. Having determined that suitable specimens exist in one of the constituent biospecimens banks, the researcher can generate a Web-based request form to obtain additional information from the appropriate bank operator(s). Access to specimens is restricted to Stanford Faculty and Staff or affiliates., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.
Proper citation: STRIDE Virtual Biospecimen Bank (RRID:SCR_008667) Copy
http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/4050?geography=South+Carolina
The Charleston Heart Study (CHS) is a prospective cohort study of 2,283 subjects (1,394 whites, 889 blacks) in which risk factors of coronary disease have been examined for the past 43 years. The CHS began enrolling a random selection of community residents who in 1960 were 35 years of age and older ����?? including men and women, black and white. A unique feature of this cohort is the fact that 102 high socio-economic status (SES) black men were purposefully included. The primary hypothesis of the original study was to investigate racial differences in the manifestation and risk factors for coronary disease. Over the ensuing 40+ years, a variety of outcome measurements were incorporated into the re-examination of the participants, including psychosocial, behavioral, aging and functional measures. Subjects were initially interviewed and examined in 1960 and 1963. Subsequent interviews and examinations took place during the following time periods: 1974-1975, 1984-1985, 1987-1989, and 1990-1991. During the most recent questionnaire (1990-1991), the following topics were examined: general health, smoking, functional disability, physical disability, cardiovascular health, sexual dysfunction, cognitive disability, depression, coffee consumption, medication history, medical history, nutrition, and body image. In addition, serum samples and blood pressure measurements were taken, and a physical exam was performed by a physician. A search of the National Death Index was completed through the year 2000, matching individuals with date and cause of death. Vital status of the CHS study participants through 12-31-2000 is presented below. Dead * White Men 539 (82.5%) * White Women 500 (67.5%) * Black Men 281 (84.4%) * High SES Black Men 59 (57.8%) * Black Women 343 (75.6%) Data Availability: Datasets are stored in the National Archive of Computerized Data on Aging (NACDA) in the ICPSR as Study No. 4050. Data are also available from the Medical University of South Carolina Library; contact a PI, Paul J. Nietert, nieterpj (at) musc.edu for further information. * Dates of Study: 1960-2000 * Study Features: Longitudinal, Minority Oversamples, Anthropometric Measures * Sample Size: 1960: 2,283 (baseline) Link ICPSR, http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/04050
Proper citation: Charleston Heart Study (RRID:SCR_008895) Copy
http://umanitoba.ca/institutes/manitoba_institute_cell_biology/MBTB/Index4.htm
A collection of tissue and related clinical data for breast cancer. The Bank stores three types of information on each case within a secure location in CancerCare Manitoba. This information relates to the tissue, clinical, and follow-up information. Tissue information includes the composition of the tissue, the size and type of tumor. Clinical information includes the patient age, clinical symptoms and the results of clinical tests such as x-rays. Follow-up information includes the type of treatment after surgery and the response to this treatment. The Bank provides an important resource both for breast cancer research at the University of Manitoba and for researchers across Canada and internationally. Researchers are charged to cover the costs of storage and release but no tissue or information is sold. The Bank has supported over 50 research studies on breast cancer across North America and Europe. Information is never released from the Bank with any label that might allow it to be traced to an individual. Information is only released as part of a set of anonymized cases, where each case is labeled by an anonymous tumor bank number and consists of a section of tissue with related information. Researchers can apply to study these cases only through a review process and if they obtain approval for their research project from an institutional ethics review board. If approved, researchers are provided with tissue sections and the related clinical information from a set of typically 100 or more ����??cases����??. These cases are carefully selected from the computer database on the basis of selection criteria such as size and type of tumor that are relevant to the research question under study. During the assessment of each breast biopsy specimen small tissue samples are taken by Pathologists to process and examine under a microscope and these samples are then stored as a ����??clinical archive����??. After all diagnosis has been completed the Bank organizes these tissues and related clinical data into ����??cases����?? for both future research and future clinical purposes and stores these ����??cases����?? in CancerCare Manitoba. All cases are distinguished by a Tumor Bank number but are anonymous due to the absence of any tag that might allow it to be traced to an individual patient.
Proper citation: Manitoba Breast Tumor Bank (RRID:SCR_008723) Copy
A 20 year, 20,000 person, open longitudinal epidemiological study of a cohort town. GAZEL was not constructed to answer a specific question rather it was designed to help analyze a wide range of scientific problems and is accessible to the community of researchers specializing in epidemiology. Translation is not available for all pages. The GAZEL cohort, set up in 1989 by Inserm Unit 88 (subsequently Unit 687), in cooperation with several departments of ��lectricit�� de France-Gaz de France (EDF-GDF), was a public utility firm in France involved in production, transmission and distribution of energy. GAZEL initially included 20 624 volunteers working at EDF-GDF (15 010 men and 5614 women), aged from 35 to 50 years. In accordance with its purpose as a scientific research platform, the GAZEL cohort is permanently open to epidemiologic research teams. Today, more than 50 projects on very diversified themes have been set up in GAZEL by some 20 teams, French, belonging to different bodies, and foreign (Germany, Belgium, Canada, Great Britain, Sweden, Finland, and USA).
Proper citation: Gazel Database (RRID:SCR_008962) Copy
https://bbgre.brc.iop.kcl.ac.uk
A database and associated tools for investigating the genetic basis of neurodisability. It combines phenotype information from patients with neurodevelopmental and behavioral problems with clinical genetic data, and displays this information on the human genome map. Basic access to genetic information (deletions, duplications) relating to participants with neurodevelopmental disorders is provided without an account; access to the full dataset requires an account. The genetic information that is available to view comprises potentially pathogenic copy number variation across the genome, detected by array comparative genome hybridization (aCGH) using a customized 44K oligonucleotide array.
Proper citation: Brain and Body Genetic Resource Exchange (RRID:SCR_008959) Copy
hiPathDB is an integrated pathway database that combines the curated human pathway data of NCI-Nature PID, Reactome, BioCarta and KEGG. In total, it includes 1661 pathways consisting of 8976 distinct physical entities. (2010.03.09) hiPathDB provides two different types of integration. The pathway-level integration, conceptually a simple collection of individual pathways, was achieved by devising an elaborate model that takes distinct features of four databases into account and subsequently reformatting all pathways in accordance with our model. The entity-level integration creates a single unified pathway that encompasses all pathways by merging common components. Even though the detailed molecular-level information such as complex formation or post-translational modifications tends to be lost, such integration makes it possible to investigate signaling network over the entire pathways and allows identification of pathway cross-talks. Another strong merit of hiPathDB is the built-in pathway visualization module that supports explorative studies of complex networks in an interactive fashion. The layout algorithm is optimized for virtually automatic visualization of the pathways.
Proper citation: hiPathDB - human integrated Pathway DB with facile visualization (RRID:SCR_008900) Copy
A cross-national data archive located in Luxembourg that contains two primary databases: the Luxembourg Income Study Database (LIS Database) includes income microdata from a large number of countries at multiple points in time. The newer Luxembourg Wealth Study Database(LWS Database) includes wealth microdata from a smaller selection of countries. Both databases include labor market and demographic data as well. Our mission is to enable, facilitate, promote, and conduct cross-national comparative research on socio-economic outcomes and on the institutional factors that shape those outcomes. Since its beginning in 1983, the LIS has grown into a cooperative research project with a membership that includes countries in Europe, North America, and Australia. The database now contains information for more than 30 countries with datasets that span up to three decades. The LIS databank has a total of over 140 datasets covering the period 1968 to 2005. The primary objectives of the LIS are as follows: * Test the feasibility for creating a database containing social and economic data collected in household surveys from different countries; * Provide a method which allows researchers to use the data under restrictions required by the countries providing the data; * Create a system that allows research requests to be received from and returned to users at remote locations; and * Promote comparative research on the social and economic status of various populations and subgroups in different countries. Data Availability: The dataset is accessed globally via electronic mail networks. Extensive documentation concerning technical aspects of the survey data, variables list, and the social institutions of income provision in member countries are also available to users through the project Website. * Dates of Study: 1968-present * Study Features: International * Sample Size: 30+ Countries Link: * ICPSR: http://www.icpsr.umich.edu/icpsrweb/ICPSR/studies/00150
Proper citation: Luxembourg Income Study (RRID:SCR_008732) Copy
http://www.powmri.edu.au/research/facilities/brain-bank
Not yet vetted by NIF curator
Proper citation: Australian Brain Bank (RRID:SCR_010569) Copy
http://www2.som.uq.edu.au/SOM/RESEARCH/ROYALCHILDRENS/Pages/TumorBank.aspx
Not yet vetted by NIF curator
Proper citation: Queensland Childrens Tumour Bank (RRID:SCR_010575) Copy
An Antibody supplier. Now called Xtant Medical.
Proper citation: Bacterin International, Inc. (RRID:SCR_010579) Copy
As the integral bridge between researcher and patient, ProMedDx helps the world''s leading in-vitro diagnostic and research organizations fulfill the promise of disease eradication and healthier living. From a constantly evolving, high-grade Specimen Bank to a complete range of customized Clinical Services to a secure, state-of-the-art BioStorage, ProMedDx delivers the industry''s most trusted and comprehensive human biological solutions from collection to handling, storage, and transportation. Human biologics such as blood, plasma, urine, and tissue specimens possess crucial clues that can unlock the mystery of disease and lead to life altering treatments. As one of the most respected suppliers of human clinical specimens and patient samples, we are entrusted with a vital role in the advancement of medical research. ProMedDx is proud to further the scientific quest for discovery. That''s why we maintain an inventory of more than 1.8 million high quality healthy, and diseased human clinical specimens collected under IRB, ICH, and GCP guidelines and in adherence with HIPAA privacy regulations. Although our extensive Specimen Bank offers a wide ranging inventory, ProMedDx experts are also poised to help clients with clinical trial services or custom sample collections. ProMedDx has created one of the industry''s most secure, cost-efficient, and state-of-the-art specimen and tissue banks for for the storage of biological specimens. Strategically located between Boston, Massachusetts and Providence, Rhode Island, our on-site facility offers uncompromised Safety & Security. Best-in-class Technology runs our BioStorage facility and our centralized Logistics procedures have set new industry standards in packaging and shipping.
Proper citation: ProMedDx (RRID:SCR_010542) Copy
A commercial organization in regenerative medicine, focused in the areas of bio-active wound healing and soft tissue regeneration.
Proper citation: Organogenesis, Inc. (RRID:SCR_010555) Copy
http://www.ims.u-tokyo.ac.jp/cellpro/cord.html
Not yet vetted by NIF curator
Proper citation: Tokyo Cord Blood Bank (Japanese) (RRID:SCR_010560) Copy
http://ods.od.nih.gov/Research/CARDS_Database.aspx
Database of federally funded research projects pertaining to dietary supplements. CARDS contains projects funded by the United States Department of Agriculture (USDA), the Department of Defense (DOD) and the Institutes and Centers (ICs) of the National Institutes of Health (NIH) beginning with fiscal year 1999, the first year that NIH ICs began reporting research related to dietary supplements. Projects funded by other Federal agencies will be added to CARDS as they become available. The Office of Dietary Supplements (ODS) will post notices on its website and listserv when CARDS updates are completed. Codes assigned to each research project allow the CARDS user to identify: * research related to specific dietary supplement ingredients; for example, vitamin E or St. John''''s wort * the type of study; for example, a Phase III study or an animal study * health outcomes or biological effects; for example, osteoporosis or antioxidant function * whether the research is directly related or indirectly related to dietary supplements. For example, a clinical trial comparing bone density in women given a daily calcium supplement versus a placebo would be classified as directly related to dietary supplements. A study examining the activation of steroid hormone receptors by supplemental vitamin D in cell culture would be classified as indirectly related to dietary supplements because the direct physiological or health effects of vitamin D supplementation are not being studied. A search of the CARDS database can be used to sort and tabulate information for a variety of purposes. For example, a researcher may want to know which ICs at the NIH fund research on herbal supplement ingredients. A consumer may want to know if the Federal government is supporting research on a popular dietary supplement ingredient such as vitamin C.
Proper citation: CARDS Database (RRID:SCR_009011) Copy
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