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Resource Name Proper Citation Abbreviations Resource Type Description Keywords Resource Relationships Related Condition Funding Defining Citation Availability Specification URL Alternate IDs Alternate URLs Old URLs Parent Organization Resource ID Synonyms Record Last Update Mentions Count
nmf
 
Resource Report
Resource Website
10+ mentions
nmf (RRID:SCR_024284) software toolkit, software resource Software R package provides framework to perform Non-negative Matrix Factorization.Used for nonnegative matrix factorization.Implements set of already published algorithms and seeding methods, and provides framework to test, develop and plug new/custom algorithms. Most of the built-in algorithms have been optimized in C++, and the main interface function provides an easy way of performing parallel computations on multicore machines. perform Non-negative Matrix Factorization, nonnegative matrix factorization, is listed by: Debian PMID:20598126 Free, Available for download, Freely available, https://sources.debian.org/src/r-cran-nmf/ SCR_024284 2026-08-05 10:48:02 12
proc
 
Resource Report
Resource Website
10+ mentions
proc (RRID:SCR_024286) software toolkit, software resource Software R tools for visualizing, smoothing and comparing receiver operating characteristic. Partial area under curve AUC can be compared with statistical tests based on U-statistics or bootstrap. Confidence intervals can be computed for (p)AUC or ROC curves. visualizing, smoothing and comparing receiver operating characteristic, is listed by: Debian Free, Available for download, Freely available, OMICS_17528 https://sources.debian.org/src/r-cran-proc/ SCR_024286 2026-08-05 10:48:01 32
psyphy
 
Resource Report
Resource Website
psyphy (RRID:SCR_024289) software toolkit, software resource Software R package useful in analyzing data from psychophysical experiments.Includes functions for calculating d' from several different experimental designs, links for m-alternative forced-choice data to be used with binomial family in glm and self-Start functions for estimating gamma values for CRT screen calibrations. analyzing data from psychophysical experiments, analyzing data, psychophysical experiments, is listed by: Debian Free, Available for download, Freely available, https://sources.debian.org/src/r-cran-psyphy/ SCR_024289 2026-08-05 10:48:01 0
ruby-bio
 
Resource Report
Resource Website
ruby-bio (RRID:SCR_024322) software toolkit, software resource Software tools and libraries for bioinformatics and molecular biology, for the Ruby programming language. BioRuby has components for sequence analysis, pathway analysis, protein modelling and phylogenetic analysis; it supports many widely used data formats and provides easy access to databases, external programs and public web services, including BLAST, KEGG, GenBank, MEDLINE and GO. Ruby programming language, sequence analysis, pathway analysis, protein modelling, phylogenetic analysis, is listed by: Debian Free, Available for download, Freely available, https://sources.debian.org/src/ruby-bio/ SCR_024322 2026-08-05 10:48:01 0
mediana
 
Resource Report
Resource Website
mediana (RRID:SCR_024281) software toolkit, software resource Software R package for clinical trial simulations based on Clinical Scenario Evaluation approach. The package supports broad class of data models, analysis strategies and commonly used evaluation criteria. clinical trial simulations, Clinical Scenario Evaluation approach, is listed by: Debian Free, Available for download, Freely available, https://sources.debian.org/src/r-cran-mediana/ SCR_024281 2026-08-05 10:48:02 0
itertools
 
Resource Report
Resource Website
itertools (RRID:SCR_024282) software toolkit, software resource Software R package for creating iterators, many patterned after functions in the Python itertools module, and others patterned after functions in the 'snow' package. creating iterators, is listed by: Debian Free, Available for download, Freely available, https://sources.debian.org/src/r-cran-itertools/ SCR_024282 2026-08-05 10:48:01 0
optimalcutpoints
 
Resource Report
Resource Website
10+ mentions
optimalcutpoints (RRID:SCR_024283) software toolkit, software resource Software R package to compute optimal cutpoints for diagnostic tests or continuous markers.Used for selecting optimal cutoffs, analysis and diagnostic test accuracy measures. compute optimal cutpoints, selecting optimal cutoffs, analysis and diagnostic test accuracy measures, is listed by: Debian Free, Available for download, Freely available, https://sources.debian.org/src/r-cran-optimalcutpoints/ SCR_024283 2026-08-05 10:48:01 10
rpact
 
Resource Report
Resource Website
rpact (RRID:SCR_024300) software toolkit, software resource Software R package for design and analysis of confirmatory adaptive clinical trials with continuous, binary, and survival endpoints. design and analysis of confirmatory adaptive clinical trials, clinical trials with continuous, binary, survival endpoints, is listed by: Debian Free, Available for download, Freely available, https://sources.debian.org/src/r-cran-rpact/ SCR_024300 2026-08-05 10:48:01 0
shazam
 
Resource Report
Resource Website
10+ mentions
shazam (RRID:SCR_024301) software toolkit, software resource Software R package provides computational framework for analyzing mutations in immunoglobulin sequences. Immunoglobulin Somatic Hypermutation Analysis. computational framework, analyzing mutations, immunoglobulin sequences, is listed by: Debian Free, Available for download, Freely available, OMICS_29370 https://sources.debian.org/src/r-cran-shazam/ SCR_024301 2026-08-05 10:48:01 27
Unicycler
 
Resource Report
Resource Website
100+ mentions
Unicycler (RRID:SCR_024380) software toolkit, software resource Software assembly pipeline for bacterial genomes. Used for resolving bacterial genome assemblies from short and long sequencing reads. Can assemble Illumina only read sets where it functions as SPAdes-optimiser. Can assembly long read only sets for PacBio or Nanopore where it runs miniasm+Racon pipeline. assembly pipeline, bacterial genomes, resolving bacterial genome assemblies, short and long sequencing reads, is listed by: Debian PMID:28594827 Free, Available for download, Freely available, OMICS_14591 https://sources.debian.org/src/unicycler/ SCR_024380 unicycler 2026-08-05 10:48:03 449
tab2mage
 
Resource Report
Resource Website
tab2mage (RRID:SCR_024359) software toolkit, software resource Software package written and supported by ArrayExpress curation team, which aims to ease the process of submitting large microarray experiment datasets to our public repository database. ease process of submitting large microarray experiment datasets, submitting to public repository database, is listed by: Debian Free, Available for download, Freely available, https://sources.debian.org/src/tab2mage/ SCR_024359 Tab2MAGE 2026-08-05 10:48:02 0
GeMoMa
 
Resource Report
Resource Website
100+ mentions
GeMoMa (RRID:SCR_017646) software application, simulation software, software resource Software tool as homology based gene prediction program that predicts gene models in target species based on gene models in evolutionary related reference species. Utilizes amino acid sequence conservation, intron position conservation, and RNA-seq data to accurately predict protein-coding transcripts. Supports combination of predictions based on several reference species allowing to transfer high quality annotation of different reference species to target species. Homology, based, gene, prediction, model, target, evolutionary, related, reference, species, sequence, conservation, intron, position, RNAseq, data, protein, coding, transcript, bio.tools is listed by: bio.tools
is listed by: Debian
works with: GUSHR
PMID:31020559 Free, Available for download, Freely available biotools:gemoma https://bio.tools/gemoma SCR_017646 Gene Model Mapper 2026-08-05 10:46:49 135
MB-GAN
 
Resource Report
Resource Website
1+ mentions
MB-GAN (RRID:SCR_019289) software application, simulation software, software resource Software tool as deep learning simulation framework for simulating realistic microbiome data. Can automatically learn from given microbial abundances and compute simulated abundances that are indistinguishable from it. Metagenomics, deep learning, generative adversarial network, microbiome data simulation, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: University of Texas at Dallas; Texas; USA
DOI:10.1101/863977 Free, Available for download, Freely available biotools:mb-gan https://bio.tools/mb-gan SCR_019289 Microbiome Simulation via Generative Adversarial Network 2026-08-05 10:47:13 1
GNU Octave
 
Resource Report
Resource Website
100+ mentions
GNU Octave (RRID:SCR_014398) programming language, software resource A high-level language, primarily intended for numerical computations. It provides a convenient command line interface for solving linear and nonlinear problems numerically, and for performing other numerical experiments. It may also be used as a batch-oriented language. Octave has extensive tools for solving common numerical linear algebra problems, finding the roots of nonlinear equations, functions written in the Octave language, or by using dynamically loaded modules written in C, C++, Fortran, or other languages., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025. command-line, free software, array programming, programming language, mathematics, reproducible research, is listed by: Debian
is related to: Mastrave modelling library
works with: CoSMoMVPA
works with: Empirical Gramian Framework
DOI:10.1016/j.jprocont.2012.04.006 THIS RESOURCE IS NO LONGER IN SERVICE https://directory.fsf.org/wiki/Octave, https://sources.debian.org/src/octave/ SCR_014398 Octave 2026-08-05 10:46:09 244
CARD
 
Resource Report
Resource Website
100+ mentions
CARD (RRID:SCR_023995) data or information resource, database Comprehensive antibiotic resistance database. Bioinformatic database of resistance genes, their products and associated phenotypes. Antibiotic resistance data, resistance genes and associated phenotypes, resistance genes, phenotypes, is listed by: Debian PMID:31665441 Free, Available for download, Freely available r3d100012727 https://doi.org/10.17616/R3WN59 https://sources.debian.org/src/card-rgi/ SCR_023995 card-rgi, Comprehensive Antibiotic Resistance Database, The Comprehensive Antibiotic Resistance Database 2026-08-05 10:47:56 211
PILGRM
 
Resource Report
Resource Website
1+ mentions
PILGRM (RRID:SCR_004749) PILGRIM data analysis service, production service resource, analysis service resource, service resource PILGRM (the platform for interactive learning by genomics results mining) puts advanced supervised analysis techniques applied to enormous gene expression compendia into the hands of bench biologists. This flexible system empowers its users to answer diverse biological questions that are often outside of the scope of common databases in a data-driven manner. This capability allows domain experts to quickly and easily generate hypotheses about biological processes, tissues or diseases of interest. Specifically PILGRM helps biologists generate these hypotheses by analyzing the expression levels of known relevant genes in large compendia of microarray data. PILGRM is for the biologist with a set of proteins relevant to a disease, biological function or tissue of interest who wants to find additional players in that process. It uses a data driven method that provides added value for literature search results by mining compendia of publicly available gene expression datasets using lists of relevant and irrelevant genes (standards). PILGRM produces publication quality PDFs usable as supplementary material to describe the computational approach, standards and datasets. Each PILGRM analysis starts with an important biological question (e.g. What genes are relevant for breast cancer but not mammary tissue in general?). For PILGRM to discover relevant genes, it needs examples of both genes that you would (positive) and would not (negative) find interesting. Lists of these genes are what we call standards and in PILGRM you can build your own standards or you can use standards from common sources that we pre-load for your convenience. PILGRM lets you build your own literature-documented standards so that processes, disease, and tissues that are not well covered in databases of tissue expression, disease, or function can still be used for an analysis. data mining, gene expression, user directed data mining, bio.tools is listed by: Debian
is listed by: bio.tools
has parent organization: Princeton University; New Jersey; USA
NSF DBI-0546275;
NIGMS R01 GM071966;
NIGMS P50 GM071508;
NCI T32 CA005928
PMID:21653547 nlx_75372, biotools:pilgrm https://bio.tools/pilgrm SCR_004749 Platform for Interactive Learning by Genomics Results Mining 2026-08-06 09:26:13 1
HSSP
 
Resource Report
Resource Website
10+ mentions
HSSP (RRID:SCR_004953) HSSP database, data or information resource HSSP (homology-derived structures of proteins) is a derived database merging structural (2-D and 3-D) and sequence information (1-D). For each protein of known 3D structure from the Protein Data Bank, the database has a file with all sequence homologues, properly aligned to the PDB protein. Homologues are very likely to have the same 3D structure as the PDB protein to which they have been aligned. As a result, the database is not only a database of sequence aligned sequence families, but it is also a database of implied secondary and tertiary structures. Likely secondary structure are carried over from the PDB protein to each homologous protein. Tertiary structure models can be built by fitting the sequence of the homologue as aligned into the 3D template of the protein of known structure. Special software is needed to construct 3D models by homology, such WHATIF by Gert Vriend or MaxSprout by Liisa Holm and Chris Sander. The command rsync can be used to obtain a local copy of the HSSP. We appreciate receiving an Email from people who do so, but there are no strings attached. Everybody can freely download the files, academia and industry alike. If your institute''s firewall doesn''t allow you to use the (preferred) rsync way of obtaining HSSP files, feel free to work with FTP. The files are in that case available from: ftp://ftp.cmbi.ru.nl//pub/molbio/data/hssp/ gold standard, bio.tools is listed by: bio.tools
is listed by: Debian
has parent organization: Radboud University; Nijmegen; The Netherlands
PMID:2017436 biotools:hssp, nlx_91976 https://bio.tools/hssp SCR_004953 Homology-derived Secondary Structure of Proteins, homology-derived structures of proteins, HSSP - Homology derived Secondary Structure of Proteins, HSSP database, HSSP - Homology-derived Secondary Structure of Proteins, Homology derived Secondary Structure of Proteins 2026-08-06 09:26:15 33
STING Report
 
Resource Report
Resource Website
1+ mentions
STING Report (RRID:SCR_005121) STING database, data or information resource Sting Report is a database of amino acid sequences, structures, functions, and parameters. It allows users to easily extract from the Blue Star Sting Database detailed but focused information about an individual amino acid, which belongs to a structure described in a PDB file. The extracted information is presented as a series of GIF images and a table, which are generated by Blue Star Sting modules and contain values of up to 125 sequence/structure/function descriptors/parameters. The HTML page resulting from a query on Sting Report, containing the GIF images and the table, is printable, and can also be composed and visualized at a computer platform with elementary configuration. amino acid, amino acid function, amino acid sequence, amino acid structure, bio.tools is listed by: Debian
is listed by: bio.tools
PMID:15608194 nif-0000-03498, biotools:sting_millenium https://bio.tools/sting_millenium SCR_005121 Blue Star Sting Report 2026-08-06 09:26:17 4
Information Hyperlinked Over Proteins
 
Resource Report
Resource Website
10+ mentions
Information Hyperlinked Over Proteins (RRID:SCR_004829) iHOP service resource, database, data or information resource Information system that provides a network of concurring genes and proteins extends through the scientific literature touching on phenotypes, pathologies and gene function. It provides this network as a natural way of accessing millions of PubMed abstracts. By using genes and proteins as hyperlinks between sentences and abstracts, the information in PubMed can be converted into one navigable resource, bringing all advantages of the internet to scientific literature research. Moreover, this literature network can be superimposed on experimental interaction data (e.g., yeast-two hybrid data from Drosophila melanogaster and Caenorhabditis elegans) to make possible a simultaneous analysis of new and existing knowledge. The network contains half a million sentences and 30,000 different genes from humans, mice, D. melanogaster, C. elegans, zebrafish, Arabidopsis thaliana, yeast and Escherichia coli. phenotype, gene, protein, interaction, pathology, physiology, gene network, network, literature, gene function, text-mining, bio.tools is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
is related to: PubMed
has parent organization: Autonomous University of Madrid; Madrid; Spain
European Union IST-2001- 32688;
European Union QLRT-2001-00015
PMID:15226743 Creative Commons Attribution-NoDerivs License, Works v3 biotools:ihop, nif-0000-00232, OMICS_01185 https://bio.tools/ihop SCR_004829 iHOP - Information Hyperlinked over Proteins 2026-08-06 09:26:15 24
SPOT - Biological prioritization after a SNP association study
 
Resource Report
Resource Website
500+ mentions
SPOT - Biological prioritization after a SNP association study (RRID:SCR_005193) SPOT data analysis service, production service resource, analysis service resource, service resource A web-based tool for using biological databases to prioritize single nucleotide polymorphisms (SNPs) after a genome-wide association study (GWAS). The site allows users to upload a list of SNPs and GWAS P-values and returns a prioritized list of SNPs using the GIN method. Users can specify candidate genes or genomic regions with custom levels of prioritization. The results can be downloaded or viewed in the browser where users can interactively explore the details of each SNP, including graphical representations of the genomic information network (GIN) method. For investigators interested in incorporating biological databases into a post-GWAS SNP selection strategy, the SPOT web tool is an easily implemented and flexible solution. single nucleotide polymorphism, genome-wide association study, linkage disequilibrium, gene, genomic region, p-value, bio.tools, FASEB list is listed by: OMICtools
is listed by: Debian
is listed by: bio.tools
has parent organization: University of Southern California; Los Angeles; USA
PMID:20529875 biotools:spot, OMICS_00189 https://bio.tools/spot SCR_005193 2026-08-06 09:26:22 512

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