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https://unclineberger.org/tgl/

Core facility within Lineberger Comprehensive Cancer Center that performs sample processing for the molecular, pathologic, and genomic characterization of patient-derived specimens using high-end instrumentation and state-of-the-art methods. Service offerings include nucleic acid extraction, gene expression profiling, spatial genomics, next-generation sequencing library preparation, and high-throughput sequencing. Protocols leverage the reproducibility and reliability of automated instrumentation to minimize batch effects and processing errors (e.g. sample swaps). These workflows have been continuously optimized over the last decade, with a sample-to-answer historic success rate of ~90% for the >15,000 FFPE samples TGL has processed.

Proper citation: University of North Carolina at Chapel Hill Translational Genomics Lab Core Facility (RRID:SCR_025231) Copy   

•   Source: SciCrunch Registry

http://www.pittbiospecimencore.pitt.edu/

Pitt Biospecimen Core provides human sample procurement in multiple UPMC hospitals across Pittsburgh. Standard operating procedures for procurement and processing are developed for each project in partnership with each study's principal investigator. A rigorous quality assurance program ensures SOP compliance. In addition to specimen banking and pathology consultation, research histology services by expert histology specialists are also available.

Proper citation: University of Pittsburgh Pitt Biospecimen Core Facility (RRID:SCR_025229) Copy   

•   Source: SciCrunch Registry

https://www.ualberta.ca/biological-sciences/services/mf/index.html

Core services include paraffin embedding and histology, epifluorescence microscopy and confocal LSM, SEM and TEM sample prep and imaging.

Proper citation: University of Alberta Biological Sciences Advanced Microscopy Core Facility (RRID:SCR_025329) Copy   

•   Source: SciCrunch Registry

https://nbcc.lunenfeld.ca/facilities/high-res-imaging

Advanced imaging facility for microscopy needs where users have access to technologies in advanced microscopy.Services include consultation on experimental design, advice on appropriate systems, training and support for assisted and unassisted use, as well as help with data analysis and image generation for publications. Applications include Fluorescence and brightfield image acquisition; Whole-slide scanning; Dynamic live-cell imaging; Super-resolution imaging.

Proper citation: Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre Advanced Imaging Core Facility (RRID:SCR_025389) Copy   

•   Source: SciCrunch Registry

https://www.uottawa.ca/research-innovation/transmission-electron-microscopy

Core Facility offers imaging and Transmission Electron Microscopy (TEM) sample processing services, in collaboration with CHEO’s Electron Microscopy Laboratory. Provides comprehensive TEM imaging services, hands-on training for independent instrument use, and expert support in sample preparation and processing.

Proper citation: University of Ottawa Electron Microscopy Core Facility (RRID:SCR_025398) Copy   

•   Source: SciCrunch Registry

https://nbcc.lunenfeld.ca/facilities/high-content-screening

Provides optical imaging and analysis of fixed and live cells. Services include assistance with selecting imaging platform, developing customized imaging assays, training in imaging and data analysis and assistance with image/data preparation for presentations and publications. Applications include Multi-plate based imaging applications; High-resolution cell characterization and sub-cellular localization using IN cell Analyzers;3D Spheroid and Organoid imaging using a Nikon A1R BioPipeline;Live-cell analysis (confluency, growth tracking) using Incucyte - imaging within incubator.

Proper citation: Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre High-Content Screening Core Facility (RRID:SCR_025391) Copy   

•   Source: SciCrunch Registry

https://hillmanresearch.upmc.edu/research/facilities/cytometry/

Supports analytical cytometry and cell sorting. Offers NanoString Digital Spatial Analyzer and nCounter service and support.

Proper citation: University of Pittsburgh Hillman Cancer Center Cytometry Core Facility (RRID:SCR_025361) Copy   

•   Source: SciCrunch Registry

https://louisville.edu/micronano

Expertise resides in micro and nanotechnology, sensors, transducers, microelectromechanical systems (MEMS), advanced materials, biomedical devices, space and governmental applications.Offers SEM and TEM imaging services for biological samples.

Proper citation: University of Louisville Micro/Nano Technology Center Core Facility (RRID:SCR_025359) Copy   

•   Source: SciCrunch Registry

https://nbcc.lunenfeld.ca/facilities/proteomics

Provides mass-spectrometry based identification and quantification of proteins. Facility specializes in functional proteomics with focus on protein proximity and protein interaction mapping. Services include access to reagents, plasmids, sample preparation, mass spectrometry, and data analysis.Applications include: proximity-dependent biotinylation mapping to identify neighboring proteins in cells ,protein-protein interaction mapping,post-translational modification identification (with a focus on phosphorylation),differential protein abundance,chemical proteomics (identifying on- and off-target binding to small molecules or biologics)., THIS RESOURCE IS NO LONGER IN SERVICE. Documented on September 16,2025.

Proper citation: Lunenfeld-Tanenbaum Research Institute Network Biology Collaborative Centre Proteomics Core Facility (RRID:SCR_025375) Copy   

•   Source: SciCrunch Registry

https://hillmanresearch.upmc.edu/research/facilities/cancer-bioinformatics/

Provides bioinformatics support for translational genomics using sequencing, arrays, single cell, and other technologies.

Proper citation: University of Pittsburgh Hillman Cancer Center Cancer Bioinformatic Services Core Facility (RRID:SCR_025356) Copy   

•   Source: SciCrunch Registry

https://vet.purdue.edu/ctr/

Core facilities pre-clinical studies of orthopedic devices intended for animal and human use, clinical studies of treatment and prevention of respiratory diseases in horses and animal clinical trials evaluating the treatment of bladder cancer in Scottish Terriers, an animal model of human bladder cancer.

Proper citation: Purdue University Center for Comparative Translational Research Core Facility (RRID:SCR_025541) Copy   

•   Source: SciCrunch Registry

https://cancer.iu.edu/research/shared-facilities/pmtc/crt.html

Conduct validated and highly reproducible in vitro and in vivo angiogenesis, endothelial, hematopoietic and multi-parametric flow cytometry assays and their role in normal and patient-related hematologic and cardiovascular disorders. The ABC also manages an IncuCyte Zoom and Seahorse XFp.

Proper citation: Indiana University School of Medicine Cellular Response Technologies Core Facility (RRID:SCR_025535) Copy   

•   Source: SciCrunch Registry

https://www.purdue.edu/discoverypark/drug-discovery/resources/cgf/index.php

Provides access to large chemical and CRISPR libraries and state-of-the-art instrumentation in high-throughput screening (HTS) and high content screening (HCS) campaigns to facilitate the identification of chemical or genomic tools to study biological pathways and the discovery of lead agents for the development of novel therapeutics and diagnostic approaches. The facility also provides assistance in assay development

Proper citation: Purdue University Chemical Genomics Core Facility (RRID:SCR_025537) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/service-cores/facilities/proteomics

Provides numerous types of mass-spectrometry based proteomics services, including global proteome quantitation, affinity purification-mass spectrometry, targeted mass spectrometry analysis for precise quantitation, post-translational modification analysis, and a variety of consulting services.

Proper citation: Indiana University School of Medicine Proteome Analysis Core Facility (RRID:SCR_025538) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/research-centers/neurosciences/Core-Services/Electrophysiology-Core

Electrophysiology Core performs rodent brain slice electrophysiological recordings to measure brain cell function.

Proper citation: Indiana University School of Medicine Electrophysiology Core Facility (RRID:SCR_025546) Copy   

•   Source: SciCrunch Registry

https://biostats.indiana.edu/

Provides study design and data analysis for health-related research, including grant or protocol development, sample size and power calculations, data management, data analysis, and scientific writing. Support can range from hourly support on a short-term project to including a biostatistician on a long-term grant collaboration.

Proper citation: Indiana University Bloomington Biostatistics Consulting Center Core Facility (RRID:SCR_025530) Copy   

•   Source: SciCrunch Registry

https://birck.research.purdue.edu/

Nanofabrication cleanroom, bio-pharma clean room, nanometrology laboratories, nanomanufacturing laboratories, microelectronics and microfuidics fabrication and testing laboratories, 3D cell culture and tissue chip laboratories.

Proper citation: Purdue University Birck Nanotechnology Center Core Facility (RRID:SCR_025532) Copy   

•   Source: SciCrunch Registry

https://medschool.cuanschutz.edu/immunology-and-microbiology/core-labs/gemm-core

Core provides full-service mouse genetic engineering support to researchers.Helps to select model for your research program, design and build any requisite constructs and reagents, and produce live mice. The most popular requests are for CRISPR-based gene edited mice and transgenic mice. Services include creation of engineered alleles for knockouts, conditional knockouts, SNP knockins, tag and marker insertions, deletions of up to 300kb, duplications, and transgenic alleles. These novel mouse models have been made on a wide spectrum of genetic background strains, including but not limited to C57BL/6J, C57BL/6N, NOD, BALB/cJ, FVB/Crl, NSGS, various 129 substrains, collaborative cross strains, and on mice that are already genetically modified. Breeding and genotyping program supports breeding to establish germline transmission and can also create cohorts for investigators. Provides strain cryopreservation, rederivation and rescue services, as well as cryostorage.

Proper citation: University of Colorado Anschutz Medical Campus Genetically Engineered Murine Models Core Facility (RRID:SCR_025491) Copy   

•   Source: SciCrunch Registry

https://mpimagingcore.weebly.com/

Imaging Core provides equipment and services available to all UM researchers. Offers training and assistance in range of light microscope techniques including spinning disk confocal, super resolution imaging, lightsheet imaging of cleared organ and stereology systems. Offers image analysis software (Imaris neuroscience package) including 3D image rendering, surface creation, spot detection and filament tracing.

Proper citation: University of Miami The Miami Project Imaging Core Facility (RRID:SCR_025492) Copy   

•   Source: SciCrunch Registry

https://medicine.iu.edu/research-centers/computational-biology-bioinformatics/bioinformatics-core

Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets. Core offers services including Next Generation Sequence Data Analysis; Microarray Data Analysis; Proteomics Data Analysis;Multi-omics Data Integration;Statistical Genetics;Pharmacokinetics/Pharmacodynamics Data Analysis; Drug Absorption, Disposition, Metabolism, Elimination and Transportation Prediction, and Drug Exposure Prediction;Public Domain Database Access and Custom Data Annotation.

Proper citation: Indiana University School of Medicine Bioinformatics Core Facility (RRID:SCR_025526) Copy   

•   Source: SciCrunch Registry