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https://medicine.iu.edu/biostatistics
Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.
Proper citation: Indiana University School of Medicine Biostatistics and Health Data Science Core Facility (RRID:SCR_025528) Copy
https://medicine.iu.edu/service-cores/facilities/genome-editing
Provides access to genome editing technologies by assisting with generation of genetically modified mouse models and cell lines.
Proper citation: Indiana University School of Medicine Genome Editing Center Core Facility (RRID:SCR_025553) Copy
Provides evidence-based services, training, coaching and consultation across range of local community and state stakeholder networks e.g., families, medical providers, school personnel, community organizations. This involvement and integration in addressing the behavioral, educational, and vocational needs of consumers across a range of ages i.e., early childhood through adulthood, functioning and disability types has assisted in: providing consultative expertise related to assessment and intervention with autism spectrum disorder and related developmental e.g., developmental and/or intellectual disabilities or neurodevelopmental disorders; reaching extensive audience for recruitment efforts; facilitating efforts related to community-based mixed methods, clinical trials and other research endeavors e.g., survey development and dissemination, behavioral assessment and intervention related to individuals with ASD/DD/ID across lifespan.
Proper citation: Indiana University School of Medicine HANDS In Autism Interdisciplinary Training and Resource Center Core Facility (RRID:SCR_025554) Copy
https://medicine.iu.edu/service-cores/facilities/histology
Provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility. Histology Core is core facility of the Indiana Center for Musculoskeletal Health and part of the Bone and Body Composition Core of the Indiana Clinical Translational Sciences Institute (CTSI). Histology Core provides histological services for basic science (non-clinical) research. Both mineralized (plastic embedded) and soft tissue (paraffin embedded) specimens can be prepared by the facility.
Proper citation: Indiana University School of Medicine Histology and Histomorphometry Core Facility (RRID:SCR_025556) Copy
https://medicine.iu.edu/service-cores/facilities/electron-microscopy
Offers cryo-electron microscopy, transmission electron microscopy, and scanning electron microscopy. Provides technical services to help design and then implement experiments needing each type of microscopy.
Proper citation: Indiana University School of Medicine Center for Electron Microscopy Core Facility (RRID:SCR_025587) Copy
Core develops and uses gene-targeting technology to investigate pathophysiological roles of genes of blood coagulation, anticoagulation, and fibrinolytic pathways in hemostasis, with associated relevance to embryonic development, cancer, infection, and inflammation.
Proper citation: University of Notre Dame Keck Center for Transgene Research Core Facility (RRID:SCR_025588) Copy
Provides access and training for confocal and super-resolution light microscopy systems with support for experimental design and data visualization.
Proper citation: Indiana University Bloomington Light Microscopy Imaging Center Core Facility (RRID:SCR_025597) Copy
Core supports research in chemistry, biochemistry, molecular biology, engineering and related fields. The MRRC operates six solution-state NMR spectrometers (400 to 800 MHz), a solid-state 300 MHz NMR instrument, and an X-band EPR spectrometer. Most instruments are equipped with sample changers for increased sample throughput.
Proper citation: Notre Dame University Magnetic Resonance Research Center Core Facility (RRID:SCR_025599) Copy
https://research.med.psu.edu/core-facilities/pulmonary-immunology-physiology/
Core provides development and testing of small animal models to be used for pre-clinical pulmonary research. BSL2 facility that allows the assessment of pulmonary function related to airway hyper-responsiveness, ventilation-induced lung injury, postnatal lung development, airway remodeling, chronic inflammation, allergy, environmental exposures and infection. Services offered include oxygen profiling, infection and treatment; ability to deliver, measure and test pre-clinical potential of therapeutic interventions via aerosol; and housing of small animals.
Proper citation: Penn State College of Medicine Pulmonary Immunology and Physiology Core Facility (RRID:SCR_025624) Copy
Neuroimaging facility that enables cutting-edge neuroscience research and training using non-invasive imaging methodologies, including both MRI and EEG.
Proper citation: Indiana University Bloomington Imaging Research Core Facility (RRID:SCR_025564) Copy
https://medicine.iu.edu/internal-medicine/specialties/infectious-diseases/research/support-services
Performs clinical research studies including evaluation of new molecular technologies for diagnosis of wide array of sexually transmitted and newly emerging pathogens, developing novel assays to meet the needs of individual research collaborators, and tailoring services to successfully meet study objectives. The laboratory has the capability to identify and type human papillomavirus.
Proper citation: Indiana University School of Medicine Infectious Diseases Laboratory Core Facility (RRID:SCR_025565) Copy
https://medicine.iu.edu/service-cores/facilities/immunohistochemistry
Immunohistochemistry Research Lab specializes in assisting researchers with histologic and immunohistochemical labeling of cells or tissue sections as well as collaborations with surgical pathologists.
Proper citation: Indiana University School of Medicine Immunohistochemistry Research Lab Core Facility (RRID:SCR_025566) Copy
https://indianactsi.org/servicecores/core/60/
Core provides following services: Brachial artery flow-mediated dilation; Brachial artery nitroglycerin-mediated dilation; Carotid artery intima media thickness.
Proper citation: Indiana University School of Medicine Human Vascular Imaging Core Facility (RRID:SCR_025558) Copy
https://vet.purdue.edu/ctr/histology/
Full service histology laboratory that provides general histology, immunohistochemistry, frozen sectioning, decalcified and undecalcified bone histology, and slide digitization services. Board certified veterinary pathologists are also available for consultation.
Proper citation: Purdue University Histology Research Laboratory Core Facility (RRID:SCR_025559) Copy
https://biotech.unl.edu/single-cell/
Facility provides access to Chromium iX platform from 10X Genomics. This allows user to barcode single cells or nuclei and process them for single cell RNA-seq, single nucleus ATAC-seq or single nucleus Multiome ATC + Gene Expression protocols.
Proper citation: University of Nebraska Lincoln Single Cell Genomics Core Facility (RRID:SCR_025609) Copy
https://medicine.iu.edu/internal-medicine/research/centers/biological-microscopy
Provides researchers with access to laser-scanning confocal, 2-photon and epi-fluorescence microscopes. Personnel train individual researchers to use all imaging systems and provide expert help in design, conduct and analysis of imaging studies. As necessary, center personnel can also be hired to conduct microscopy studies for laboratories lacking necessary expertise.
Proper citation: Indiana University School of Medicine Center for Biological Microscopy Core Facility (RRID:SCR_025568) Copy
https://www.organoids.pitt.edu/
Core has large collection of unique patient-derived organoids (PDOs). Staff provides high-quality training in organoid development and culture, consultation services to assist with experimental design, execution, and data analysis.
Proper citation: University of Pittsburgh Organoid Research Core Facility (RRID:SCR_025698) Copy
http://noncodingrna.org/bioinformatics-unit/
BIDMC Bioinformatics Core is Unit of the Precision RNA Medicine Core and provides support for management, integration and contextual analysis of biological high-throughput data, training on tools, databases and best practice.
Proper citation: Harvard Medical School Beth Israel Deaconess Medical Center Bioinformatics Core Facility (RRID:SCR_025859) Copy
https://www.childrenshospital.org/research/cores/molecular-genetics-core/contact-us
Provides genomic technology services and expertise. Services offered include Nanopore PromethION sequencing, Electronic optical mapping on Nabsys, Optical Genome mapping on Bionano Saphyr, NGS (Illumina-based), Sanger Sequencing, Single cell analysis/RNAseq, Transcriptomic spatial profiling, Gene expression analysis , Droplet Digital PCR & qPCR, Microsatellite/fragment analysis, SNP genotyping , Chromosomal microarray analysis, Sample prep and QC, Project consultation, Bioinformatics support.
Proper citation: Boston Children's Hospital Molecular Genetics Core Facility (RRID:SCR_025866) Copy
https://cryoem.hms.harvard.edu
Joint effort by Harvard Medical School, Dana-Farber Cancer Institute, Boston Childrens Hospital, and Massachusetts General Hospital to provide cryo-EM instrumentation and expertise for Harvard structural biology community. Facility offers consultation and training by staff in specimen preparation, microscope operation, image acquisition, and data analysis.
Proper citation: Harvard Medical School Harvard Cryo-Electron Microscopy Center for Structural Biology Core Facility (RRID:SCR_025841) Copy
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