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SciCrunch Registry is a curated repository of scientific resources, with a focus on biomedical resources, including tools, databases, and core facilities - visit SciCrunch to register your resource.
https://medicine.iu.edu/service-cores/facilities/histology
Provides histological and histomorphometric services for basic science (non-clinical) research. Mineralized (plastic embedded), soft tissue (paraffin embedded), and cryopreserved specimens can be processed by the facility. Histology Core is core facility of the Indiana Center for Musculoskeletal Health and part of the Bone and Body Composition Core of the Indiana Clinical Translational Sciences Institute (CTSI). Histology Core provides histological services for basic science (non-clinical) research. Both mineralized (plastic embedded) and soft tissue (paraffin embedded) specimens can be prepared by the facility.
Proper citation: Indiana University School of Medicine Histology and Histomorphometry Core Facility (RRID:SCR_025556) Copy
https://medicine.iu.edu/research-centers/neurosciences/Core-Services/Electrophysiology-Core
Electrophysiology Core performs rodent brain slice electrophysiological recordings to measure brain cell function.
Proper citation: Indiana University School of Medicine Electrophysiology Core Facility (RRID:SCR_025546) Copy
Provides study design and data analysis for health-related research, including grant or protocol development, sample size and power calculations, data management, data analysis, and scientific writing. Support can range from hourly support on a short-term project to including a biostatistician on a long-term grant collaboration.
Proper citation: Indiana University Bloomington Biostatistics Consulting Center Core Facility (RRID:SCR_025530) Copy
https://birck.research.purdue.edu/
Nanofabrication cleanroom, bio-pharma clean room, nanometrology laboratories, nanomanufacturing laboratories, microelectronics and microfuidics fabrication and testing laboratories, 3D cell culture and tissue chip laboratories.
Proper citation: Purdue University Birck Nanotechnology Center Core Facility (RRID:SCR_025532) Copy
https://medschool.cuanschutz.edu/immunology-and-microbiology/core-labs/gemm-core
Core provides full-service mouse genetic engineering support to researchers.Helps to select model for your research program, design and build any requisite constructs and reagents, and produce live mice. The most popular requests are for CRISPR-based gene edited mice and transgenic mice. Services include creation of engineered alleles for knockouts, conditional knockouts, SNP knockins, tag and marker insertions, deletions of up to 300kb, duplications, and transgenic alleles. These novel mouse models have been made on a wide spectrum of genetic background strains, including but not limited to C57BL/6J, C57BL/6N, NOD, BALB/cJ, FVB/Crl, NSGS, various 129 substrains, collaborative cross strains, and on mice that are already genetically modified. Breeding and genotyping program supports breeding to establish germline transmission and can also create cohorts for investigators. Provides strain cryopreservation, rederivation and rescue services, as well as cryostorage.
Proper citation: University of Colorado Anschutz Medical Campus Genetically Engineered Murine Models Core Facility (RRID:SCR_025491) Copy
https://mpimagingcore.weebly.com/
Imaging Core provides equipment and services available to all UM researchers. Offers training and assistance in range of light microscope techniques including spinning disk confocal, super resolution imaging, lightsheet imaging of cleared organ and stereology systems. Offers image analysis software (Imaris neuroscience package) including 3D image rendering, surface creation, spot detection and filament tracing.
Proper citation: University of Miami The Miami Project Imaging Core Facility (RRID:SCR_025492) Copy
https://medicine.iu.edu/research-centers/computational-biology-bioinformatics/bioinformatics-core
Bioinformatics Core provides advanced computation and informatics approaches to analyze large and complex biological datasets. Core offers services including Next Generation Sequence Data Analysis; Microarray Data Analysis; Proteomics Data Analysis;Multi-omics Data Integration;Statistical Genetics;Pharmacokinetics/Pharmacodynamics Data Analysis; Drug Absorption, Disposition, Metabolism, Elimination and Transportation Prediction, and Drug Exposure Prediction;Public Domain Database Access and Custom Data Annotation.
Proper citation: Indiana University School of Medicine Bioinformatics Core Facility (RRID:SCR_025526) Copy
https://medicine.iu.edu/biostatistics
Core collaborates with investigators in the planning, statistical design, data management, and analysis of health related clinical, laboratory and epidemiological research projects. Grant development assistance is provided without charge.
Proper citation: Indiana University School of Medicine Biostatistics and Health Data Science Core Facility (RRID:SCR_025528) Copy
https://indianactsi.org/servicecores/core/60/
Core provides following services: Brachial artery flow-mediated dilation; Brachial artery nitroglycerin-mediated dilation; Carotid artery intima media thickness.
Proper citation: Indiana University School of Medicine Human Vascular Imaging Core Facility (RRID:SCR_025558) Copy
https://vet.purdue.edu/ctr/histology/
Full service histology laboratory that provides general histology, immunohistochemistry, frozen sectioning, decalcified and undecalcified bone histology, and slide digitization services. Board certified veterinary pathologists are also available for consultation.
Proper citation: Purdue University Histology Research Laboratory Core Facility (RRID:SCR_025559) Copy
https://medicine.iu.edu/service-cores/facilities/electron-microscopy
Offers cryo-electron microscopy, transmission electron microscopy, and scanning electron microscopy. Provides technical services to help design and then implement experiments needing each type of microscopy.
Proper citation: Indiana University School of Medicine Center for Electron Microscopy Core Facility (RRID:SCR_025587) Copy
Core develops and uses gene-targeting technology to investigate pathophysiological roles of genes of blood coagulation, anticoagulation, and fibrinolytic pathways in hemostasis, with associated relevance to embryonic development, cancer, infection, and inflammation.
Proper citation: University of Notre Dame Keck Center for Transgene Research Core Facility (RRID:SCR_025588) Copy
Provides access and training for confocal and super-resolution light microscopy systems with support for experimental design and data visualization.
Proper citation: Indiana University Bloomington Light Microscopy Imaging Center Core Facility (RRID:SCR_025597) Copy
Core supports research in chemistry, biochemistry, molecular biology, engineering and related fields. The MRRC operates six solution-state NMR spectrometers (400 to 800 MHz), a solid-state 300 MHz NMR instrument, and an X-band EPR spectrometer. Most instruments are equipped with sample changers for increased sample throughput.
Proper citation: Notre Dame University Magnetic Resonance Research Center Core Facility (RRID:SCR_025599) Copy
https://research.med.psu.edu/core-facilities/pulmonary-immunology-physiology/
Core provides development and testing of small animal models to be used for pre-clinical pulmonary research. BSL2 facility that allows the assessment of pulmonary function related to airway hyper-responsiveness, ventilation-induced lung injury, postnatal lung development, airway remodeling, chronic inflammation, allergy, environmental exposures and infection. Services offered include oxygen profiling, infection and treatment; ability to deliver, measure and test pre-clinical potential of therapeutic interventions via aerosol; and housing of small animals.
Proper citation: Penn State College of Medicine Pulmonary Immunology and Physiology Core Facility (RRID:SCR_025624) Copy
Neuroimaging facility that enables cutting-edge neuroscience research and training using non-invasive imaging methodologies, including both MRI and EEG.
Proper citation: Indiana University Bloomington Imaging Research Core Facility (RRID:SCR_025564) Copy
https://medicine.iu.edu/internal-medicine/specialties/infectious-diseases/research/support-services
Performs clinical research studies including evaluation of new molecular technologies for diagnosis of wide array of sexually transmitted and newly emerging pathogens, developing novel assays to meet the needs of individual research collaborators, and tailoring services to successfully meet study objectives. The laboratory has the capability to identify and type human papillomavirus.
Proper citation: Indiana University School of Medicine Infectious Diseases Laboratory Core Facility (RRID:SCR_025565) Copy
https://medicine.iu.edu/service-cores/facilities/immunohistochemistry
Immunohistochemistry Research Lab specializes in assisting researchers with histologic and immunohistochemical labeling of cells or tissue sections as well as collaborations with surgical pathologists.
Proper citation: Indiana University School of Medicine Immunohistochemistry Research Lab Core Facility (RRID:SCR_025566) Copy
https://biotech.unl.edu/single-cell/
Facility provides access to Chromium iX platform from 10X Genomics. This allows user to barcode single cells or nuclei and process them for single cell RNA-seq, single nucleus ATAC-seq or single nucleus Multiome ATC + Gene Expression protocols.
Proper citation: University of Nebraska Lincoln Single Cell Genomics Core Facility (RRID:SCR_025609) Copy
https://medicine.iu.edu/internal-medicine/research/centers/biological-microscopy
Provides researchers with access to laser-scanning confocal, 2-photon and epi-fluorescence microscopes. Personnel train individual researchers to use all imaging systems and provide expert help in design, conduct and analysis of imaging studies. As necessary, center personnel can also be hired to conduct microscopy studies for laboratories lacking necessary expertise.
Proper citation: Indiana University School of Medicine Center for Biological Microscopy Core Facility (RRID:SCR_025568) Copy
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